KEGG   Macaca nemestrina (pig-tailed macaque): 105475065
Entry
105475065         CDS       T08765                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase isoform X4
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
mni  Macaca nemestrina (pig-tailed macaque)
Pathway
mni00670  One carbon pool by folate
mni00790  Folate biosynthesis
mni01100  Metabolic pathways
mni01240  Biosynthesis of cofactors
mni01523  Antifolate resistance
mni04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:mni00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    105475065 (DHFR)
   00670 One carbon pool by folate
    105475065 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    105475065 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    105475065 (DHFR)
Enzymes [BR:mni01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     105475065 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 105475065
NCBI-ProteinID: XP_011728321
Ensembl: ENSMNEG00000033103
LinkDB
Position
Unknown
AA seq 298 aa
MAAREQGPAGSASPRPQFPGVCGREPAVTLPCAGAGGGTSPAQIGTRGRGGHNFAPILTA
RSVLTSGLGGAPAAVMVRSLNCIVAVSQNMGIGKNGDLPWPPLRKGGPDWIRIPLFCCAG
GKVADFCPDPAARDHQTGFVNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLK
GRINLVLSRELKEPPQGAHFLARSLDDALKLTEQPELANKVDMIWIVGGSSVYKEAMNHP
GHLKLFVTRIMQDFESDTFLPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
NT seq 897 nt   +upstreamnt  +downstreamnt
atggcagcccgggaacagggccctgccgggagcgcgagcccgcggccgcagttcccaggc
gtctgcgggcgcgagcccgccgtgaccctgccgtgcgccggggcggggggcgggacctcg
cctgcacaaataggaacaagagggcggggcggccacaatttcgcgccaatcttgaccgcg
cgttctgttttaactagcgggctcggaggtgctccagctgctgtcatggttcgttcgcta
aactgcatcgtcgctgtgtcccagaacatgggcatcggcaagaacggggacctgccctgg
ccgccgctcaggaagggtgggcccgactggattcggattccccttttctgctgcgcagga
ggcaaagttgctgatttctgcccggatcctgctgccagagaccaccaaacaggctttgtg
aatgaattcagatatttccagagaatgaccacaacctcttcagtagaaggtaaacagaat
ctagtgattatgggtaagaagacttggttctccattcctgagaagaatcgacctttaaag
ggtagaattaatttagttctcagcagagaactcaaggaacctccacaaggagctcatttt
cttgccagaagtctggatgatgccttaaaacttactgaacaaccagaattagcaaataaa
gtagacatgatttggatagttggtggcagttctgtttataaggaagccatgaatcaccca
ggccatcttaaactatttgtgacaaggatcatgcaagactttgaaagtgacacctttctt
ccagaaattgatttggagaaatataaacttctaccagaatacccaggtgttctctctgat
gtccaagaggagaaaggcattaagtacaaatttgaagtatatgagaagaatgattaa

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