Macaca nemestrina (pig-tailed macaque): 105475680 Help Entry 105475680         CDS       T08765                                  Symbol IL6 Name (RefSeq) interleukin-6 isoform X1   KO K05405   interleukin 6 Organism mni  Macaca nemestrina (pig-tailed macaque) Pathway mni01521   EGFR tyrosine kinase inhibitor resistance mni01523   Antifolate resistance mni04060   Cytokine-cytokine receptor interaction mni04061   Viral protein interaction with cytokine and cytokine receptor mni04066   HIF-1 signaling pathway mni04068   FoxO signaling pathway mni04151   PI3K-Akt signaling pathway mni04218   Cellular senescence mni04620   Toll-like receptor signaling pathway mni04621   NOD-like receptor signaling pathway mni04623   Cytosolic DNA-sensing pathway mni04625   C-type lectin receptor signaling pathway mni04630   JAK-STAT signaling pathway mni04640   Hematopoietic cell lineage mni04657   IL-17 signaling pathway mni04659   Th17 cell differentiation mni04668   TNF signaling pathway mni04672   Intestinal immune network for IgA production mni04931   Insulin resistance mni04932   Non-alcoholic fatty liver disease mni04933   AGE-RAGE signaling pathway in diabetic complications mni04936   Alcoholic liver disease mni05010   Alzheimer disease mni05020   Prion disease mni05022   Pathways of neurodegeneration - multiple diseases mni05132   Salmonella infection mni05133   Pertussis mni05134   Legionellosis mni05135   Yersinia infection mni05142   Chagas disease mni05143   African trypanosomiasis mni05144   Malaria mni05146   Amoebiasis mni05152   Tuberculosis mni05161   Hepatitis B mni05162   Measles mni05163   Human cytomegalovirus infection mni05164   Influenza A mni05166   Human T-cell leukemia virus 1 infection mni05167   Kaposi sarcoma-associated herpesvirus infection mni05168   Herpes simplex virus 1 infection mni05169   Epstein-Barr virus infection mni05171   Coronavirus disease - COVID-19 mni05200   Pathways in cancer mni05202   Transcriptional misregulation in cancer mni05321   Inflammatory bowel disease mni05323   Rheumatoid arthritis mni05332   Graft-versus-host disease mni05410   Hypertrophic cardiomyopathy mni05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mni00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     105475680 (IL6)    04668 TNF signaling pathway     105475680 (IL6)    04066 HIF-1 signaling pathway     105475680 (IL6)    04068 FoxO signaling pathway     105475680 (IL6)    04151 PI3K-Akt signaling pathway     105475680 (IL6)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     105475680 (IL6)    04061 Viral protein interaction with cytokine and cytokine receptor     105475680 (IL6)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     105475680 (IL6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     105475680 (IL6)    04620 Toll-like receptor signaling pathway     105475680 (IL6)    04621 NOD-like receptor signaling pathway     105475680 (IL6)    04623 Cytosolic DNA-sensing pathway     105475680 (IL6)    04625 C-type lectin receptor signaling pathway     105475680 (IL6)    04659 Th17 cell differentiation     105475680 (IL6)    04657 IL-17 signaling pathway     105475680 (IL6)    04672 Intestinal immune network for IgA production     105475680 (IL6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105475680 (IL6)    05202 Transcriptional misregulation in cancer     105475680 (IL6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105475680 (IL6)    05161 Hepatitis B     105475680 (IL6)    05171 Coronavirus disease - COVID-19     105475680 (IL6)    05164 Influenza A     105475680 (IL6)    05162 Measles     105475680 (IL6)    05168 Herpes simplex virus 1 infection     105475680 (IL6)    05163 Human cytomegalovirus infection     105475680 (IL6)    05167 Kaposi sarcoma-associated herpesvirus infection     105475680 (IL6)    05169 Epstein-Barr virus infection     105475680 (IL6)   09171 Infectious disease: bacterial    05132 Salmonella infection     105475680 (IL6)    05135 Yersinia infection     105475680 (IL6)    05133 Pertussis     105475680 (IL6)    05134 Legionellosis     105475680 (IL6)    05152 Tuberculosis     105475680 (IL6)   09174 Infectious disease: parasitic    05146 Amoebiasis     105475680 (IL6)    05144 Malaria     105475680 (IL6)    05142 Chagas disease     105475680 (IL6)    05143 African trypanosomiasis     105475680 (IL6)   09163 Immune disease    05323 Rheumatoid arthritis     105475680 (IL6)    05321 Inflammatory bowel disease     105475680 (IL6)    05332 Graft-versus-host disease     105475680 (IL6)   09164 Neurodegenerative disease    05010 Alzheimer disease     105475680 (IL6)    05020 Prion disease     105475680 (IL6)    05022 Pathways of neurodegeneration - multiple diseases     105475680 (IL6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105475680 (IL6)    05410 Hypertrophic cardiomyopathy     105475680 (IL6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     105475680 (IL6)    04932 Non-alcoholic fatty liver disease     105475680 (IL6)    04931 Insulin resistance     105475680 (IL6)    04933 AGE-RAGE signaling pathway in diabetic complications     105475680 (IL6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105475680 (IL6)    01523 Antifolate resistance     105475680 (IL6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:mni04052]     105475680 (IL6) Cytokines and neuropeptides [BR:mni04052]  Cytokines   Interleukins    105475680 (IL6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL6 Motif Other DBs NCBI-GeneID:  105475680 NCBI-ProteinID:  XP_011729446 Ensembl:  ENSMNEG00000003406 LinkDB All DBs Position Unknown AA seq 281 aa AA seqDB search MPQGPPLTSPTKSPPGTKEKLYLPSRNPDMNSVSTSKCRKSLALERPAAVEPCVREGCVA QGGLAGGQQQRQAPSCAVSSPRRSLPSGTGAFGPVAFSLGLLLVLPAAFPAPVLPGEDSK DVAAPHSQPLTSSERIDKHIRYILDGISALRKETCNRSNMCESSKEALAENNLNLPKMAE KDGCFQSGFNEDTCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKK VGVSSFPHLGVGEDRLKDSVLDNSGMHCHFQKRRLHVNKKV NT seq 846 nt NT seq  +upstreamnt  +downstreamnt atgccacaaggtcctcctttgacatccccaacaaagagcccaccaggaacgaaagagaag ctctatctgccctccaggaacccagatatgaactccgtctccacaagtaagtgcaggaaa tccctagccctggaacggccagcggcggtcgagccctgtgtgagggaggggtgtgtggcc cagggagggctggcgggcggccagcagcagaggcaggctcccagctgtgctgtcagctca ccccgccgctcgctcccctccggcacaggcgccttcggtccagttgccttctccctgggg ctgctcctggtgttgcctgctgccttccccgccccagtactcccaggagaagattccaaa gatgtagccgccccacacagccagccactgacctcttcagaacgaattgacaaacacatt cggtacatcctcgacggcatctcagccctgagaaaggagacatgtaacaggagtaacatg tgtgaaagcagcaaagaggcactggcagaaaacaacctgaaccttccaaagatggctgaa aaagatggatgcttccaatctggattcaatgaggacacttgcctggtgaaaatcatcact ggtcttttggagtttgaggtatacctagagtacctccagaacaggtttgagagtagtgag gagcaagccagagctgtgcaaatgagtacaaaagtcctgatccagttcctgcagaaaaag gtgggtgtgtcctccttccctcaccttggtgtgggagaagacaggctcaaagacagtgtc ctggacaactcagggatgcattgccacttccaaaagagaaggctacatgtaaacaaaaaa gtctga

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