Macaca nemestrina (pig-tailed macaque): 105485304 Help Entry 105485304         CDS       T08765                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism mni  Macaca nemestrina (pig-tailed macaque) Pathway mni04022   cGMP-PKG signaling pathway mni04068   FoxO signaling pathway mni04081   Hormone signaling mni04140   Autophagy - animal mni04152   AMPK signaling pathway mni04211   Longevity regulating pathway mni04213   Longevity regulating pathway - multiple species mni04910   Insulin signaling pathway mni04920   Adipocytokine signaling pathway mni04923   Regulation of lipolysis in adipocytes mni04930   Type II diabetes mellitus mni04931   Insulin resistance mni04932   Non-alcoholic fatty liver disease mni04935   Growth hormone synthesis, secretion and action mni05010   Alzheimer disease mni05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:mni00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     105485304 (IRS2)    04022 cGMP-PKG signaling pathway     105485304 (IRS2)    04152 AMPK signaling pathway     105485304 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     105485304 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     105485304 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105485304 (IRS2)    04923 Regulation of lipolysis in adipocytes     105485304 (IRS2)    04920 Adipocytokine signaling pathway     105485304 (IRS2)    04935 Growth hormone synthesis, secretion and action     105485304 (IRS2)   09149 Aging    04211 Longevity regulating pathway     105485304 (IRS2)    04213 Longevity regulating pathway - multiple species     105485304 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     105485304 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     105485304 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     105485304 (IRS2)    04932 Non-alcoholic fatty liver disease     105485304 (IRS2)    04931 Insulin resistance     105485304 (IRS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  105485304 NCBI-ProteinID:  XP_024649721 Ensembl:  ENSMNEG00000032762 LinkDB All DBs Position Unknown AA seq 1334 aa AA seqDB search MASPPRHGPPGPASGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGTGGDEA TAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE YFAVAAENEQEQEGWYRALTDLVSEGRAAAADAPPTAAPAASCSASLPGALGGSAGAEDT YGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLM NIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPR SKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRT ASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGG ALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSS GSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGGGEFYGYM TMDRPLSHCGRPYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRA TFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALA GSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAATVPPAGPAGPAPTSAAGRTFPAS GGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLLNGDYLNVSPSDAVTTGTPPDF FSAALHAGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQA TPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGLLGQRGRAVRPTRLSLEGLPSLPS MHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTP GTSSDSRQRSPLSDYMNLDFSSPKSPKPGARSGHPVGSLDALLSPEASSPYPPLPPRPSA SPSSSLQPPPPPPPPGELYRLPPASATATVQGPGAASSSDTGDNGDYTEMAFGVAATPPQ PIAAPAKPEAVRVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRR RHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGGVPGGGDEPPTSPR QLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLP PQPQPQPQSPLPQPGDKNSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPANTYASID FLSHHLKEATIVKE NT seq 4005 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgcggcacgggccgcccgggccggcgagcggagacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcacgggcggcgacgaggcg acggcgggaggggggtcggcgccgcagccgccgcggctcgagtactacgagagcgagaaa aagtggcggagcaaggcaggcgcgccgaagcgggtgatcgcgctcgactgctgcctgaac atcaacaagcgtgccgacgccaagcacaagtacctgatcgccctctacaccaaggacgag tacttcgccgtggccgccgagaacgagcaggagcaggagggctggtaccgcgcgctcacc gacctggtcagcgagggccgcgcggccgccgcagacgcgccccccaccgccgcgcccgcc gcgtcctgcagcgcctctctgcccggcgccctgggcggctctgccggcgccgaggacacc tacgggctggtggcgcccgccacggccgcctaccgcgaggtgtggcaggtgaacctgaag cccaagggtctgggccagagcaagaacctgacgggcgtttaccgtctgtgcctgtcggcg cgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgacgctgcagctcatg aacatccgccgctgcggccactcggacagcttcttcttcatcgaggtgggccgctcggcc gtcacgggtcccggcgagctgtggatgcaggcggatgactcggtggtggcgcagaacata cacgagaccatcctggaggccatgaaggcgctcaaagagctcttcgagttccggccacgc agcaagagccagtcgtcggggtcgtcggccacacaccctatcagcgtccccggcgcgcgc cgccaccaccacctggtcaacctaccccccagccagacgggcttggtgcgccgttcgcgt accgacagcctggccgccaccccgccggcggccaagtgcagctcgtgccgggtgcgcacc gccagcgagggcgacggcggcgcggcggcgggggcagcggccgcgggcgccaggccagtg tcggtggctgggagccccctgagccccgggccagtgcgcgcgcccctgagccgctcgcac accctgagcggcggctgcggcggccgcgggagcaaggtggcgctgctgccggcagggggc gcgctgcagcacagccgctccatgtccatgcctgtggcgcactcgccgcccgccgccacc agccccggctccctgtcgtccagcagcggccacggctcgggctcctacccgccgccgccg ggcccgcacccgcccctgccgcacccactgcaccacggccccggccagcggccctccagc ggcagcgcctccgcctcgggttcccccagcgaccccggcttcatgtccctggacgagtac ggctccagccccggcgacctgcgcgccttctgcagccaccggagcaacacgcccgagtcc atcgcggaaacgccccctgcgcgagacggcagcggcggtggtgagttctacgggtacatg accatggacaggcccctgagccactgtggccgcccctaccgcagggtctcgggagacgcg gcccaggacctggaccgagggctgcgcaagaggacctactccctgaccacgccggcccgg cagcggccggtgccccagccctcctccgcctcgctggatgagtacaccctgatgcgggcc accttctccggcagcgcaggccgcctctgcccgtcctgccccgcgtcctctcccaaggtg gcctaccacccctacccagaggactacggagatatcgagatcggctcccacaggagctcc agcagcaacctgggtgcagacgacggctacatgcccatgacgcctggcgcggccctcgcg ggcagtgggagcggcagctgcaggagcgacgactacatgcccatgagccctgccagcgtg tccgcccccaagcagatcttgcagcccagggccgccgccgctgccgccgccaccgtgccc cctgcggggcctgcggggccagcgcccacctctgcggcgggcaggacattcccggcgagc gggggcggttacaaggccagctcgccggccgagagctctcccgaggacagcgggtacatg cgcatgtggtgcggctccaagctgtccatggagcacgcggacggcaagctgctgctcaac ggggactacctcaacgtgtcccccagcgacgcggtcaccacgggcaccccgcccgacttc ttctccgcagctctgcacgccggcggggagccgctcaggggcgttcctggctgctgctac agctccttgccccgctcctacaaggccccctacacctgcggtggggacagcgaccagtac gtgctcatgagctcccccgtggggcgcatcctggaggaggagcggctggagcctcaggcc acgccagggcccagccaggcggccagcgccttcggggccggccccacgcagcccccgcac cccgtagtgccttcgcccgtgcgacccagcggcggccgccccgagggcctcctgggccag cgcggccgggctgtgcggcccacgcgcctgtccctggaggggctgcccagcctgcccagc atgcacgagtacccactgccgccagagcccaagagccccggcgagtacatcaacatcgac tttggcgagcccggtgcccgcctgtcgccgcccgcgcctcccctgctggcgtcggcggcc tcgtcctcctcgctcttgtccgccagcagcccggcctcgtcgctgggctcaggcaccccg ggcaccagcagcgacagccggcagcgctccccgctctctgactacatgaacctcgacttc agctcccccaagtctcccaagccgggcgcccggagcggccaccccgtgggctccttggac gccctcctgtcccctgaggcctcctccccgtatccgccgctgcccccgcgtccgtccgca tccccgtcgtcgtccctgcagccgccaccgccaccaccgccccccggggagctgtaccgc ttgccccctgcttcggccactgccaccgtccagggcccaggcgccgcctcgtcctcggac accggagacaatggtgactacaccgagatggctttcggtgtggccgccaccccgccgcaa cccatcgcggcccccgcgaagccagaagctgtccgcgtggccagcccgacgtcgggcgtg aagaggctgagcctcatggagcaggtgtcgggggtcgaggccttcctgcaggccagccag cccccggacccccaccgcggcgccaaggtcatccgcgcagacccacaggggggccgccgc cgccacagctccgagaccttctcctccaccacgacggtcacccccgtgtccccgtctttc gcccacaaccccaagcgccacaactcggcctccgtggaaaatgtgtctctcaggaaaagc agcgagggcggcgtgggcggcgtccctggagggggcgacgagccgcccacctcccccaga cagttgcagccggcgccccccttggcaccgcagggccggccttggaccccgggtcagccc gggggcttggtcggttgtcctgggagcggtgggtcaccaatgcgcagagagacctctgcc ggcttccagaatggtctcaactacatcgccatcgacgtgagggaggagcccgggctgcca ccccagccgcagccgcagccgcagtcgccgcttcctcagccgggagacaagaactcctgg ggtcggacccgaagcctcgggggtctcatcagcgctgtgggcgtcggcagcaccggtggc gggtgcggggggccaggtcccggtgccctgccccctgccaacacctacgctagcattgac ttcttgtcccaccacttgaaggaggccaccatcgtgaaagagtga

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