Macaca nemestrina (pig-tailed macaque): 105488506 Help Entry 105488506         CDS       T08765                                  Symbol PTK2 Name (RefSeq) focal adhesion kinase 1   KO K05725   focal adhesion kinase 1 [EC:2.7.10.2] Organism mni  Macaca nemestrina (pig-tailed macaque) Pathway mni01522   Endocrine resistance mni04012   ErbB signaling pathway mni04062   Chemokine signaling pathway mni04148   Efferocytosis mni04151   PI3K-Akt signaling pathway mni04360   Axon guidance mni04370   VEGF signaling pathway mni04510   Focal adhesion mni04670   Leukocyte transendothelial migration mni04810   Regulation of actin cytoskeleton mni04935   Growth hormone synthesis, secretion and action mni05100   Bacterial invasion of epithelial cells mni05135   Yersinia infection mni05146   Amoebiasis mni05163   Human cytomegalovirus infection mni05165   Human papillomavirus infection mni05170   Human immunodeficiency virus 1 infection mni05200   Pathways in cancer mni05202   Transcriptional misregulation in cancer mni05205   Proteoglycans in cancer mni05208   Chemical carcinogenesis - reactive oxygen species mni05222   Small cell lung cancer mni05417   Lipid and atherosclerosis mni05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:mni00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     105488506 (PTK2)    04370 VEGF signaling pathway     105488506 (PTK2)    04151 PI3K-Akt signaling pathway     105488506 (PTK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     105488506 (PTK2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     105488506 (PTK2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     105488506 (PTK2)  09150 Organismal Systems   09151 Immune system    04670 Leukocyte transendothelial migration     105488506 (PTK2)    04062 Chemokine signaling pathway     105488506 (PTK2)   09152 Endocrine system    04935 Growth hormone synthesis, secretion and action     105488506 (PTK2)   09158 Development and regeneration    04360 Axon guidance     105488506 (PTK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105488506 (PTK2)    05202 Transcriptional misregulation in cancer     105488506 (PTK2)    05205 Proteoglycans in cancer     105488506 (PTK2)    05208 Chemical carcinogenesis - reactive oxygen species     105488506 (PTK2)   09162 Cancer: specific types    05222 Small cell lung cancer     105488506 (PTK2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     105488506 (PTK2)    05163 Human cytomegalovirus infection     105488506 (PTK2)    05165 Human papillomavirus infection     105488506 (PTK2)   09171 Infectious disease: bacterial    05135 Yersinia infection     105488506 (PTK2)    05100 Bacterial invasion of epithelial cells     105488506 (PTK2)   09174 Infectious disease: parasitic    05146 Amoebiasis     105488506 (PTK2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105488506 (PTK2)    05418 Fluid shear stress and atherosclerosis     105488506 (PTK2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105488506 (PTK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mni01001]     105488506 (PTK2)    01009 Protein phosphatases and associated proteins [BR:mni01009]     105488506 (PTK2) Enzymes [BR:mni01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105488506 (PTK2) Protein kinases [BR:mni01001]  Non-receptor tyrosine kinases   FAK family    105488506 (PTK2) Protein phosphatases and associated proteins [BR:mni01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      105488506 (PTK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Focal_AT FERM_N_2 FERM_C_FAK1 Pkinase FERM_M Kinase-like FERM_F2 Haspin_kinase Motif Other DBs NCBI-GeneID:  105488506 NCBI-ProteinID:  XP_024650728 Ensembl:  ENSMNEG00000035528 LinkDB All DBs Position Unknown AA seq 1126 aa AA seqDB search MLLELAGQEALKPAGAIYMEKSGCSPFPVCWAKEYDRYLASSKIMAAAYLDPNLNHTPNS STKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHK VKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ FTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV LEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGML QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGASQSFIIRPQKEGERALPSIPKL ANSEKQGMRTHAVSVSGVSHCQHKVKKARRFLPLVFCSHDPPSTDEISGDETDDYAEIID EEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKT CKNCTSDSVREKFLQEACKFLEISVELHLIFYLENFMQEETSAKDSSDGFPDESCWDNHG SMCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDC VKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHG VKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI LEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQT NHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTALDLRGI GQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPLDCGD LTPSAGEQKNDWLLCCQLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAP PEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQ YVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH NT seq 3381 nt NT seq  +upstreamnt  +downstreamnt atgttgttggaactggcaggccaagaggccctgaaaccagcaggtgccatctatatggag aaaagcggctgtagtccatttccagtgtgttgggctaaagaatatgacagatacctagca tctagcaaaataatggcagctgcttaccttgaccccaacttgaatcacacaccaaattcg agtactaagactcacctgggtactggtatggaacgttctcctggtgcgatggagcgagta ttaaaggtctttcattattttgaaagcaatagtgagccaaccacctgggccagtattatc aggcatggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa gtaaagcatgtggcctgctatggattccgcctcagtcacctgcggtcagaggaggttcac tggcttcacgtggatatgggcgtctccagtgtgagggagaagtatgagcttgcccaccca ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag tttactgaagataagccaactttgaatttcttctatcaacaggtgaagagcgattatatg ttagagatagctgatcaagtggaccaggaaattgctttgaagttgggttgtctagaaata cggcgatcatactgggagatgcggggcaatgccctagaaaagaagtctaactatgaagta ttagaaaaagatgttggtttaaagcgattttttcctaagagtttactggattctgtcaag gccaaaacactaagaaaactgatccaacaaacatttagacaattcgccaaccttaataga gaagaaagtattctgaaattctttgagatcctgtctccagtctacagatttgataaggaa tgcttcaagtgtgctcttggttcaagctggattatttcagtggaattggcaatcggccca gaagaagggatcagttacctaacggacaagggctgcaatcccacacatcttgctgacttc actcaagtgcagaccattcagtattcaaacagtgaagataaggacagaaaaggaatgcta caactaaaaatagcaggtgcacccgagcctctgacagtgacggcaccatccctaaccatt gcggagaatatggctgacctgatagatgggtattgccggctggtgaatggagcctcgcag tcatttatcatcagaccccagaaagaaggtgaacgggctttgccatcaataccaaagttg gccaacagcgaaaagcaaggcatgcggacacacgccgtctctgtgtcaggagtcagtcac tgccaacataaagttaagaaagctaggcgctttctccctttggtcttctgttcccatgat cctccttctacggatgaaattagtggggacgaaacagatgattatgctgagattatagat gaagaagatacttacaccatgccctcaaaaagctatggaatagatgaagccagggattat gagattcaaagagaaagaatagaacttggacgatgtattggagaaggccaatttggagat gtacatcaaggcgtttatatgagtccagagaatccagctttggcggttgcaattaaaaca tgtaaaaactgtacttcggacagcgtgagagagaaatttcttcaagaagcctgtaagttt ctagaaatttctgtggaactccatttgattttctatctagaaaacttcatgcaagaagag acctcagcaaaggactcttctgatggcttcccagacgaatcctgttgggataatcatgga agcatgtgcacacttggagagctgaggtcgtttttgcaagtaaggaaatacagtttggat ctagcatctttgatcctgtatgcctatcagcttagtacagctcttgcatatctagagagc aaaagatttgtacacagggacattgctgctcggaatgttctggtgtcctcaaatgattgt gtaaaattaggagactttggattatcccgatatatggaagatagtacttactacaaagct tccaaaggaaaattgcctattaaatggatggctccagagtcaatcaattttcgacgtttt acctcagctagtgacgtatggatgtttggtgtgtgtatgtgggagatactgatgcatggt gtgaagccttttcaaggagtgaagaacaatgatgtaatcggtcgaattgaaaatggggaa agattaccaatgcctccaaattgtcctcctaccctctacagccttatgacgaaatgctgg gcctatgaccccagcaggcggcccaggtttactgaacttaaagctcagctcagcacaatc ctggaggaagagaaggctcagcaagaagaacgcatgaggatggagtccagaagacaggcc acagtgtcctgggactccggagggtctgatgaagcgccacccaagcccagcagaccgggt tatcctagtccgaggtccagcgaaggattttatcccagcccacagcacatggtacaaacc aatcattaccaggtttctggctaccctggttcacatggaatcacagccatggctggcagc atctatccaggtcaggcatctcttttggaccaaacagattcatggaatcatagacctcag gagatagcaatgtggcagcccaatgtggaggactctacagcattggacctgcgagggatt gggcaagtgttgccaacccacctgatggaagagcggctaatccgacagcaacaggaaatg gaagaagatcagcgctggctggaaaaagaggaaagatttctgaaacctgatgtgagactc tctcgaggcagtattgacagggaggatggaagtcttcagggtccgcttgattgtggtgat ctcacgccatctgctggagagcagaaaaatgactggcttctgtgttgtcagcttcagccc caggaaatcagcccccctcctactgccaacctggaccggtcaaatgataaggtgtacgag aatgtgacgggcctggtgaaagctgtcatcgagatgtccagtaaaatccagccagcccca ccagaggagtatgtccctatggtgaaggaagtcggcttggccctgaggacgttattggcc actgtggatgagaccattcccctcctaccagccagcacccaccgagagattgagatggca cagaaactattgaactctgacctgggtgagctcatcaacaagatgaaactggcccagcag tatgtcatgaccagtctccagcaagagtacaaaaagcaaatgctgactgctgctcacgcc ctggctgtggatgccaaaaacttactcgatgtcattgaccaagcaagactgaaaatgctt gggcagacgagaccacactga

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