Macaca nemestrina (pig-tailed macaque): 105493456
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Entry
105493456 CDS
T08765
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
mni
Macaca nemestrina (pig-tailed macaque)
Pathway
mni00061
Fatty acid biosynthesis
mni00620
Pyruvate metabolism
mni00640
Propanoate metabolism
mni01100
Metabolic pathways
mni04152
AMPK signaling pathway
mni04910
Insulin signaling pathway
mni04920
Adipocytokine signaling pathway
mni04922
Glucagon signaling pathway
mni04931
Insulin resistance
mni04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
mni00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
105493456 (ACACB)
00640 Propanoate metabolism
105493456 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
105493456 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
105493456 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
105493456 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
105493456 (ACACB)
04922 Glucagon signaling pathway
105493456 (ACACB)
04920 Adipocytokine signaling pathway
105493456 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
105493456 (ACACB)
04931 Insulin resistance
105493456 (ACACB)
Enzymes [BR:
mni01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
105493456 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
105493456 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
105493456 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
105493456
NCBI-ProteinID:
XP_011759430
Ensembl:
ENSMNEG00000044783
UniProt:
A0A2K6E8E6
LinkDB
All DBs
Position
Unknown
AA seq
2458 aa
AA seq
DB search
MVFLLCLSCLIFSCLTFSWLKIWGKMTDSQPITKSTSEANFILSQEPFPASDNSGETPQR
NGEDHSLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPKNPLSSSDAAPSPELQANRT
GTQGLEAPDTNGLSSSARPQGQQAGSPSKEDRKQANIKRQLMTNFILGSFDDYSSDEDSV
AGSSRESTRKGSRASLGALSLEAALTAGEAETRVSTMRPSMSGLHLVKRGREHKKLDLHR
DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT
PEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL
PELLCKNGVAFLGPPSEAMWALGDKIASTIVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK
IISVPEDVYDQGCVKDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV
QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP
LAIFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL
PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE
GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA
LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL
NVADAMFRTCMTDFLHCLERGQVLPADSLLNIVDVELIYGGIKYILKVARQSLTMFVLIM
NGCHIEIDAHRLNDGGLLLSYNGNSYTTYLKEEVDSYRITIGNKTCVFEKENDPTVLRSP
SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCVVAR
LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPIFSIK
LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP
SQQIATILDCHAATLQRKADREVFFLNTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLHV
EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD
ELTSILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP
ENLKKLIISETTIFDVLPAFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV
VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR
NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREDPIHILNVSIQCADHLEDEALVP
ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL
ELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGAEVTDHRFFIRAIIRHSDLITKEASFEY
LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPLKIEESVRSMVMRYGS
RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF
GNKQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYIYDFPEIFRQALFKLWGSPDKYPK
DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDMIVIGNDITFRIG
SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK
YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL
AYEEIVTISLVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL
GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR
APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE
TRTVEVVVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREKLPLMIFANWRGF
SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA
DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRRDLEGRLK
AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK
QEILRASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQVEDGPRSTIR
ENITYLKHDSVLKTIRGLVQENPEVAVDCVIYLSQHISPAERAQVIHLLSTMDSPAST
NT seq
7377 nt
NT seq
+upstream
nt +downstream
nt
atggtctttcttctttgtctatcttgtctgattttctcctgtctgaccttttcctggtta
aaaatctgggggaaaatgacggactcccagccaatcaccaagagtacatcagaagcaaac
ttcatcctgagccaggagccctttccagcctctgacaactcaggggagacaccgcagaga
aatggggaggaccactctctgcccaagactcccagccaggccgagccagcctcccacaaa
ggccccaaagatgctggtcggcggagaaactccctgccaccctcccaccagaagccccca
aaaaaccccctttcttccagtgacgcagcaccctccccagagctccaagccaacaggacc
gggacacaaggtctggaggccccagataccaatggcctgtcttcctcagccaggccccag
ggccagcaagctggctccccctccaaagaagacaggaagcaggcaaacatcaagaggcag
ctgatgaccaacttcatcctgggctcttttgatgactactcctccgacgaggactctgtt
gccggctcatctcgtgagtctaccaggaagggcagccgggccagcttgggggccctgtcc
ctggaggctgctctgaccgcaggtgaagctgagacccgtgtctccactatgaggccgagc
atgtcgggactccacctggtgaagaggggacgggaacacaagaagctggacctgcacaga
gactttacagtggcttctcccgctgagtttgtcacacgctttggcggggatcgggtcatc
gagaaggtgcttattgccaacaacgggatcgccgccgtgaagtgcatgcgctccatccgc
aggtgggcctatgagatgttccgcaacgagcgggccatccggtttgttgtgatggtgacc
cctgaggaccttaaggccaacgcagagtacatcaagatggcggatcagtacgtccccgtc
ccaggagggcctaataacaacaactatgccaacgtggagctgattgtggacattgccaag
agaatccctgtgcaggcggtgtgggctggctggggccatgcttccgaaaaccctaaactt
ccggagctgctgtgcaagaatggagttgctttcttaggccctcccagtgaggccatgtgg
gccttaggagataagatcgcctccaccattgtcgcccagacgctgcaggtcccaaccctg
ccctggagtggaagcggcctgacagtggagtggacagaagatgatctgcagcagggaaaa
ataatcagtgtcccagaagatgtttatgaccagggttgtgtgaaagacgtagatgagggc
ttggaggcagcagaaaaaattggttttccattgatgatcaaagcttctgaaggtggcgga
gggaagggaatccggaaggctgagagtgcggaggacttcccgatccttttcagacaagta
cagagtgagatcccaggctcgcccatctttctcatgaagctggcccagcatgcccgtcac
ctggaagttcagatcctcgccgaccagtatgggaatgctgtgtctctgtttggtcgcgac
tgctccatccagcggcggcatcagaagattgttgaggaagcaccggccaccattgccccg
ctggccatattcgagttcatggagcagtgtgccgtccgcctggccaagaccgtgggctat
gtgagtgcagggacagtggaatacctctacagccaggacggcagcttccacttcttggag
ctgaatcctcgcttgcaggtggaacatccctgcacggaaatgatcgctgacgtcaatctg
ccggctgcccagctacagatcgccatgggcgtgccactgcaccggctgaaggatatccgg
cttctgtacggagagtcgccatggggagtgactcccatttctttcgaaaccccgtcaaac
cctcccctcgcccgaggtcacgtcattgccgccagaatcaccagtgaaaacccagatgag
gggtttaagccgagctccgggactgtccaggaactgaatttccgcagcagcaagaacgtg
tggggttacttcagtgtggctgctactggaggcctgcatgagtttgcggattcccagttt
gggcactgcttctcctggggagagaaccgggaagaggccatttcgaacatggtggtggct
ttgaaggaactgtccatccgaggtgactttaggaccaccgtggaatacctcattaacctc
ctggagaccgagagcttccagaacaatgacatcgacaccgggtggttggactacctcatt
gctgagaaagtgcaggcggagaaaccggatatcatgcttggggtggtatgcggggccttg
aacgtggcggatgcgatgttcagaacgtgcatgacagatttcttacactgcctggaaagg
ggccaggtcctcccagcggattcactactgaacatcgtagatgtggaattaatttacgga
ggcattaagtacattctcaaggtggcccggcagtctctgaccatgttcgttctcatcatg
aatggctgccacatcgagattgatgcccaccggctgaacgatggggggctcctgctctcc
tacaatgggaacagctacaccacctacctgaaggaagaggttgacagttaccgaattacc
atcggcaataagacatgtgtgtttgagaaggagaatgatcctacggtcctgagatccccc
tcggctgggaagctgacacagtacacagtggaggacgggggccacgttgaggctgggagc
agctacgctgagatggaggtgatgaagatgatcatgactctgaacgtgcaggaaagtggc
cgggtgaagtacatcaagcgtccaggggccgtgctggaagcaggctgcgtggtggccagg
ctggagcttgatgacccttctaaggtccacccggctgaaccgttcacaggagaactccct
gcccagcagacactgcccatccttggagagaaactgcaccaggtcttccacagcgtcctg
gaaaacctcaccaacgtcatgagtggcttttgtctgccggagcccatttttagcataaag
ttgaaggagtgggtgcagaagctcatgatgaccctccggcatccgtcactgccgctgctg
gagctgcaggagatcatgaccagcgtggcaggccgcatcccggcccccgtggagaagtca
gtccgcagggtgatggcccagtatgccagcaacatcacctcggtgctgtgccagttcccc
agccagcagatagccaccatcctggactgccacgcagccaccctgcagcggaaggctgac
cgagaggtcttcttcctcaacacccagagcatcgtgcagttggtccagagataccgcagc
gggatccgcggctatatgaaaacagtggtgttggatctcctgagaagatacttgcatgtc
gagcaccattttcagcaagcccattacgacaagtgtgtgataaacctcagggagcagttc
aagccagacatgtcccaggtgctggactgcatcttctcccacgcacaggtggccaagaag
aaccagctggtgatcatgctgatcgatgagctgtgtggcccagacccttccctatcggac
gagctgacctccatccttaatgagctcactcagctgagcaaaagcgagcactgcaaagtg
gccctcagagcccggcagatcctgattgcctcccacctcccctcctatgagctgcggcac
aaccaggtggagtccattttcctgtctgccattgacatgtacggccatcagttctgcccc
gagaacctcaagaagttaataatttcagaaacaaccatcttcgacgtcctgcctgctttc
ttctatcacgctaacaaagtcgtgtgcatggcatccttggaggtttacgtgcggaggggc
tacatcgcctatgagttaaacagcctgcagcaccggcagctcccggacggcacctgcgtg
gtagaattccagttcatgctgccctcctcccacccaaaccggatgaccgtgcccatcagc
atcaccaaccctgacctgctgaggcacagcacagagctcttcatggacagcggcttctcc
ccactgtgccagcgcatgggggccatggtagccttcaggagattcgaggacttcaccaga
aattttgatgaagtcatctcttgcttcgccaacgtgcccaaagacacccccctcttcagc
gaggcccgcacctccctgtactccgaggatgactgcaagagcctcagagaagaccccatc
cacattctgaatgtgtccatccagtgtgcagaccacctggaggatgaggcactggtgccg
attttacggacgttcgtacagtccaagaaaaatatccttgtggattacggactccgacga
atcacattcctgattgcccaagagaaagaatttcccaagtttttcacattcagagcaaga
gatgagtttgcagaagatcgcatttaccgtcacttggagcctgccctggccttccaactg
gagctcagccggatgcgtaacttcgatctgaccgccgtgccctgtgccaaccacaagatg
cacctttacctgggtgctgccaaggtgaaggaaggggcggaagtgacggaccataggttc
ttcatccgcgccatcatcaggcactcagacctgattacaaaggaagcctccttcgagtac
ctgcagaacgagggtgagcggctgctcctggaggccatggacgagctggaggtggcgttc
aacaacaccagcgtgcgcaccgactgcaaccacatcttcctcaacttcgtgcccactgtc
atcatggaccccttgaagatcgaggagtccgtgcgctccatggttatgcgctacggcagc
cggttgtggaaactccgcgtgctgcaggctgaagtcaagatcaacatacgccagaccacc
accggcagcgctgttcccatccgcctgttcatcaccaatgagtcgggctactacctggac
atcagcctctacaaagaagtgactgactccagatccggaaatatcatgtttcactccttt
ggcaacaagcaagggccccagcacgggatgctgatcaatactccctacgtcaccaaggat
ctgctccaggccaagcgattccaggcccagtccctgggaactacctacatctatgacttc
ccagaaatattcagacaggctctctttaaactgtggggctccccagacaagtatcccaaa
gacatcctgacatacactgaattagtgttggactctcagggccagctggtggagatgaac
cgacttcctggtggaaatgaggtgggcatggtggccttcaaaatgaggtttaagacccag
gagtaccctgaaggacgggacatgatcgtcatcggcaacgatatcacctttcgcatcgga
tcctttggccctggggaggaccttctgtacctgcgggcatctgagatggcccgggcagag
ggcattcccaaaatctacgtggcagccaacagtggcgcccgtattggcatggcagaggag
atcaaacacatgttccacgtggcttgggtggacccagaagacccccacaaaggatttaaa
tacctgtacctgactccccaagactacaccagaatcagctccctgaactctgtccactgt
aaacacatcgaggaaggaggagaatccagatacatgatcacggatatcatcgggaaagat
gatggcttgggcgtggagaatctgaggggctcaggcatgattgctggggagtcctctctg
gcttacgaagagatcgtcaccattagcttggtgacctgccgagcccttgggatcggggcc
tacttggtgaggctgggccagcgagtgatccaggtggagaactctcacatcatcctcacg
ggagcaagtgctctcaacaaggtcctgggaagagaggtctacacatccaacaaccagctg
ggtggcgttcagatcatgcattacaatggcgtttcccacatcaccgtgccagatgacttt
gagggggtttataccattctggagtggctgtcctatatgccaaaggataatcacagccct
gtccctatcatcacacccactgaccccattgacagagaaattgaattcctcccatccaga
gctccctacgacccccggtggatgcttgcaggaaggcctcacccaacgctgaagggaacg
tggcagagcggattctttgaccatggcagtttcaaggaaatcatggcaccctgggcgcag
accgtggtgacaggacgagcaaggcttggggggattcccgtgggagtgattgctgtggag
acgcggactgtggaggtggtggtccctgcagaccctgccaacctggattctgaggccaag
ataattcagcaggcggggcaggtgtggttcccagactcagcctacaaaaccgcccaggcc
atcaaggacttcaaccgggagaagttgcccctgatgatctttgccaactggagggggttc
tccggtggcatgaaagacatgtatgatcaggtgctgaagtttggagcctacatcgtggat
ggcctcagacaatacaaacagcccatcctgatctatatcccaccctatgcggagctccgg
ggaggctcctgggtggtcatagatgccaccatcaacccgctgtgcatagaaatgtatgcg
gacaaagagagcagggggggtgttctggagccagaggggacagtggagattaagttccga
aagaaagatctgataaagtccatgagaaggatcgatccagcttacaagaagctcatggaa
cagctaggggaacctgatctctcagacaaggaccgcagggacctggagggccggctgaag
gctcgcgaggacctgctgctccccatctaccaccaggtggcggtgcagttcgccgacttc
cacgacacgcccggccggatgctggagaagggcgtcatatctgacatcctggagtggaag
accgcgcgcaccttcctgtattggcgtctgcgccgcctcctcctggaggaccaggtcaag
caggagatcctgcgggccagcggggagctgagtcacgtgcacatccagtccatgctgcgc
cgctggttcgtggagacggagggggctgtcaaggcctacctgtgggacaacaaccaggtg
gttgtgcagtggctagaacagcactggcaggtggaggacggcccgcgctccaccatccgc
gagaacatcacgtacctgaagcacgactctgtcctcaagaccatccgaggcctggttcaa
gaaaaccccgaggtggccgtggactgtgtgatatacctgagccagcacatcagcccagct
gagcgggcacaggtcatccacctgctgtctaccatggacagcccggcctccacctga
DBGET
integrated database retrieval system
