Macaca nemestrina (pig-tailed macaque): 105494232 Help Entry 105494232         CDS       T08765                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism mni  Macaca nemestrina (pig-tailed macaque) Pathway mni00230   Purine metabolism mni01100   Metabolic pathways mni01522   Endocrine resistance mni04015   Rap1 signaling pathway mni04020   Calcium signaling pathway mni04022   cGMP-PKG signaling pathway mni04024   cAMP signaling pathway mni04062   Chemokine signaling pathway mni04072   Phospholipase D signaling pathway mni04081   Hormone signaling mni04082   Neuroactive ligand signaling mni04114   Oocyte meiosis mni04211   Longevity regulating pathway mni04213   Longevity regulating pathway - multiple species mni04261   Adrenergic signaling in cardiomyocytes mni04270   Vascular smooth muscle contraction mni04371   Apelin signaling pathway mni04540   Gap junction mni04611   Platelet activation mni04713   Circadian entrainment mni04714   Thermogenesis mni04720   Long-term potentiation mni04723   Retrograde endocannabinoid signaling mni04724   Glutamatergic synapse mni04725   Cholinergic synapse mni04727   GABAergic synapse mni04750   Inflammatory mediator regulation of TRP channels mni04911   Insulin secretion mni04912   GnRH signaling pathway mni04913   Ovarian steroidogenesis mni04914   Progesterone-mediated oocyte maturation mni04915   Estrogen signaling pathway mni04916   Melanogenesis mni04918   Thyroid hormone synthesis mni04921   Oxytocin signaling pathway mni04923   Regulation of lipolysis in adipocytes mni04925   Aldosterone synthesis and secretion mni04926   Relaxin signaling pathway mni04927   Cortisol synthesis and secretion mni04928   Parathyroid hormone synthesis, secretion and action mni04934   Cushing syndrome mni04935   Growth hormone synthesis, secretion and action mni04970   Salivary secretion mni04971   Gastric acid secretion mni04972   Pancreatic secretion mni04976   Bile secretion mni05032   Morphine addiction mni05142   Chagas disease mni05146   Amoebiasis mni05163   Human cytomegalovirus infection mni05166   Human T-cell leukemia virus 1 infection mni05200   Pathways in cancer mni05207   Chemical carcinogenesis - receptor activation mni05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mni00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105494232 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105494232 (ADCY1)    04371 Apelin signaling pathway     105494232 (ADCY1)    04020 Calcium signaling pathway     105494232 (ADCY1)    04072 Phospholipase D signaling pathway     105494232 (ADCY1)    04024 cAMP signaling pathway     105494232 (ADCY1)    04022 cGMP-PKG signaling pathway     105494232 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     105494232 (ADCY1)    04081 Hormone signaling     105494232 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105494232 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     105494232 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105494232 (ADCY1)    04062 Chemokine signaling pathway     105494232 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     105494232 (ADCY1)    04923 Regulation of lipolysis in adipocytes     105494232 (ADCY1)    04912 GnRH signaling pathway     105494232 (ADCY1)    04913 Ovarian steroidogenesis     105494232 (ADCY1)    04915 Estrogen signaling pathway     105494232 (ADCY1)    04914 Progesterone-mediated oocyte maturation     105494232 (ADCY1)    04921 Oxytocin signaling pathway     105494232 (ADCY1)    04926 Relaxin signaling pathway     105494232 (ADCY1)    04935 Growth hormone synthesis, secretion and action     105494232 (ADCY1)    04918 Thyroid hormone synthesis     105494232 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     105494232 (ADCY1)    04916 Melanogenesis     105494232 (ADCY1)    04925 Aldosterone synthesis and secretion     105494232 (ADCY1)    04927 Cortisol synthesis and secretion     105494232 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105494232 (ADCY1)    04270 Vascular smooth muscle contraction     105494232 (ADCY1)   09154 Digestive system    04970 Salivary secretion     105494232 (ADCY1)    04971 Gastric acid secretion     105494232 (ADCY1)    04972 Pancreatic secretion     105494232 (ADCY1)    04976 Bile secretion     105494232 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     105494232 (ADCY1)    04727 GABAergic synapse     105494232 (ADCY1)    04725 Cholinergic synapse     105494232 (ADCY1)    04720 Long-term potentiation     105494232 (ADCY1)    04723 Retrograde endocannabinoid signaling     105494232 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     105494232 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     105494232 (ADCY1)    04213 Longevity regulating pathway - multiple species     105494232 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     105494232 (ADCY1)    04714 Thermogenesis     105494232 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105494232 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     105494232 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105494232 (ADCY1)    05163 Human cytomegalovirus infection     105494232 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     105494232 (ADCY1)    05142 Chagas disease     105494232 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     105494232 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105494232 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105494232 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105494232 (ADCY1) Enzymes [BR:mni01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105494232 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA DUF6594 Motif Other DBs NCBI-GeneID:  105494232 NCBI-ProteinID:  XP_011760836 LinkDB All DBs Position Unknown AA seq 894 aa AA seqDB search MYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK PPDRIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR RIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSF LKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS NVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADL NFFTLKYKHVEREQKYHQLQDEYFTSAVVLTLILAALFGLVYLLIFPQSVAVLLLLVFCI CFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSKPNS SLVVLSSGGQRTALPTLPCESTHHALLCCLVGTLPLAIFFRVSSLPKMILLSGLTTSYIL VLELSGYTRTGGGAVSGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEERED MEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELD GNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAKKSIS SHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNV ASRMDSTGVQGRIQVTEEVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQI RSLGLDRKMGPYGRAGLQGRRPPVCPMPGVSVRAGLPSHSPGQYLSSAAAGKEA NT seq 2685 nt NT seq  +upstreamnt  +downstreamnt atgtatggggtcttcgtgcggattctgactgagcgttcgcagaggaaggcattcctgcag gcccggagctgcattgaggaccgactgaggctggaggatgagaacgagaagcaggagcgg ctcctcatgagcctcctgccccggaacgttgccatggagatgaaggaggacttcctgaag ccccctgacaggattttccacaagatttacatccagaggcacgacaatgtgagcatcctg tttgctgacatcgtgggtttcacgggcttggcatcccagtgcacggcccaggagctggtg aaactcctcaatgagctcttcggcaagtttgacgagttagccacggagaaccactgtcgt cgcatcaagattctcggggactgctactactgcgtgtcaggactcacccagcccaagact gaccatgcccactgctgcgtggagatggggctcgacatgattgataccatcacatccgtg gctgaagccaccgaggtggacctgaacatgcgtgtgggtctgcacacgggcagggtcctc tgtggtgtcctgggcttgcgcaagtggcagtatgacgtgtggtccaatgatgtgaccttg gccaatgtcatggaagccgctggcctgccagggaaggttcatatcacaaagacgacccta gcgtgcttgaatggggactacgaggtagaaccaggttacggacatgagaggaacagtttc ttgaaaactcataacattgaaaccttttttattgtgccatcccatcgccgaaagatattt ccaggcctgattctctcggatataaaaccggccaagaggatgaagttcaagactgtctgc tacctgctggtgcagctcatgcactgccgaaagatgttcaaggccgagatccccttctcc aatgtcatgacctgcgaggacgatgacaagcggagggcgttgagaacagcctcagaaaaa ctcagaaaccgctcatctttttctaccaacgttgtctacaccaccccgggcactcgtgtc aacaggtacatcagccgcctcttagaagcccgccagacagagctggagatggcagacctg aacttctttaccctgaagtacaaacatgtcgaacgggagcaaaagtaccaccagcttcag gacgagtatttcaccagcgctgttgtcctcaccctcatcctggctgccttatttggcctt gtctaccttctaatattcccacagagtgtggccgtcttgctcctgctagtattctgcatc tgcttcctggtggcctgtgtcctgtacctgcacatcacccgggtccagtgttttccaggg tgcctgacgattcagattcgcactgtcctgtgtattttcatagtggtcttaatctactca gtagcccaaggatgtgtggtgggctgcctgccctgggcctggagctccaagcccaacagt tccctggtggtcctttcatctgggggccagcgcacagccctgcccaccctgccctgcgag tctacgcaccatgccctgctctgctgcctggtgggcaccctcccgctagccatatttttt cgggtgtcctccttgccaaaaatgatcctgctgtccgggctcaccacgtcctacatcctc gtactggagctcagcggatacaccaggactgggggtggtgccgtctccgggcgcagctat gagccgattgtggccatcctgctcttctcctgtgcgctggccctgcatgccaggcaggtg gacatcaggctgaggctggactacctctgggccgcacaggcagaggaggagcgagaggac atggagaaggtgaagctggacaacaggcgcatcctcttcaacctcctgccagcccacgtc gcccagcacttcctcatgtccaaccctcggaacatggacctctactaccagtcctactcc caggtgggcgtcatgtttgcctccatccccaactttaatgacttctacatcgagctggac ggcaacaacatgggggtggagtgtctgcggcttctcaacgagatcattgccgactttgac gagctcatggagaaagacttttacaaggacatagagaagatcaagaccattgggagcacc tacatggccgctgtggggctagcgcctacttcggggaccaaggctaagaagtccatctcc tcccacctgagcacgctggcagactttgccattgagatgtttgacgttctggatgaaatc aactaccagtcttacaatgattttgtcctccgagttggcatcaatgttggccccgtggtg gctggagtgattggcgctcgcaggccccagtacgacatctggggaaacacagtcaacgtg gccagtcggatggacagcacaggggtccagggcagaatccaggtgactgaggaagtccac cggctgctgaggagatgcccctaccactttgtgtgccgaggcaaagtcagtgtcaagggc aaaggcgagatgttgacatactttctagaaggcaggactgatggaaacggctcccaaatc aggtccctgggcttggatcggaaaatgggtccatatgggagagctggccttcagggcaga cgtcccccggtgtgccccatgcctggcgtctcagtcagggctgggcttccttcacactcc ccaggccagtatctgtcctctgcagcagctgggaaggaggcttag

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