Mycobacterium novum: MNVM_02330
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Entry
MNVM_02330 CDS
T06926
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mnm
Mycobacterium novum
Pathway
mnm00010
Glycolysis / Gluconeogenesis
mnm00020
Citrate cycle (TCA cycle)
mnm00620
Pyruvate metabolism
mnm00785
Lipoic acid metabolism
mnm01100
Metabolic pathways
mnm01110
Biosynthesis of secondary metabolites
mnm01120
Microbial metabolism in diverse environments
mnm01200
Carbon metabolism
mnm01210
2-Oxocarboxylic acid metabolism
Module
mnm_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mnm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MNVM_02330 (aceE)
00020 Citrate cycle (TCA cycle)
MNVM_02330 (aceE)
00620 Pyruvate metabolism
MNVM_02330 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MNVM_02330 (aceE)
Enzymes [BR:
mnm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MNVM_02330 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
BBX11152
UniProt:
A0A7I7JJM1
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Position
229064..231862
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AA seq
932 aa
AA seq
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MTTEAVHQDLGKTPSGTTEADRVRVIREGVASYLPDIDPEETSEWLESFDGLVARSGPAR
ARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFPGDEDIERRYRAWIRWNAAVM
VHRAQRPGVGVGGHISTYASSASLYEVGFNHFFRGKAHPGGGDQIFIQGHASPGIYARAF
LEGRLSTHQLDGFRQEHSHPDGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHY
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLLHVGALEGLDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNVTPDGDYQTYKANDG
GYVRQHFFGRDPRTKALVENLSDQDIWHLKRGGHDYRKVYAAYRAAVEHQGQPTVILAKT
IKGYSLGSYFAGRNATHQMKKFRPQDLKDFRDEMRIPISDAEIEENPYLPPYYHPGEDAP
EIRYLLDRRRALGGFVPQRRTRARALTLPGPEAYAAVKKGSGTQEVATTMATVRVFKELL
RDKEIGTRLVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDAELMLAYKESEVGQILH
EGINEAGSTASFTAVGTSYATHDEPMIPIYIFYSMFGFQRTGDSLWAAADQMARGFILGA
TAGRTTLTGEGLQHADGHSLLLAATNPAVVSYDPAFAFEVAHIIESGLQRMFGENPENVY
FYVTLYNEPYIQPAEPDGFDAEDVAGLLRGIYRYQKAAEPKSHAAQILASGVSMPEALRA
AELLAADWDVAADVWSVTSWGELNRDGVALERERLRHPERPAGEPYVTRALADAAGPVVA
VSDWMRAVPEQIRPWVPGTFVTLGTDGFGFSDTRTAARRYFNTDAESVAVAVLAALARDG
AIDASIPATAADRYQIDDVMAAPEQTSDSGVA
NT seq
2799 nt
NT seq
+upstream
nt +downstream
nt
ttgactaccgaggccgtgcaccaggatctgggcaaaacaccaagcggcacaaccgaagcc
gatcgggtccgagtgatccgcgagggggtggcgtcctacctgcccgacatcgaccccgaa
gagacctccgagtggctggagtccttcgacggcctggtggcccgctccggtccggcacgc
gcccgctacctgatgctgcggctgctcgaacgcgccggcgagcagcgcgtggcgatcccg
gcactcacctcgaccgactacgtcaacaccatcccgaccgaactggagccgtggtttccc
ggcgacgaggacatcgaacgccgttaccgggcgtggatccgctggaatgccgcggtcatg
gtgcatcgcgcccagcggcccggggtcggcgtcggtggtcacatctcgacctacgcatcg
tcggcctcgctctacgaagtcgggttcaaccacttcttccgcggcaaggcccaccccggc
ggcggggaccagatcttcatccagggccacgcctcccccggcatctacgcgcgcgcgttc
ctggagggccggctgagcacccatcagctcgacggcttccggcaggagcacagccatccc
gacggcggcctgccgtcctacccgcacccgcggctgatgccggacttctgggagttcccc
acggtgtcgatggggctgggcccgatgaacgccatctaccaggcgcggttcaaccactac
ctgcacgaccggggcatcaaggacacctccgaccagcacgtgtggtgctttctgggcgac
ggcgagatggacgagccggaaagccgcgggctgctgcacgtcggcgcgctggagggcctg
gacaacctgaccttcgtgatcaactgcaacctgcagcgcctcgacggcccggtgcgcggc
aacggcaagatcatccaggagctggagtcgttcttccgcggcgcgggctggaacgtgatc
aaggtggtgtggggccgcgagtgggacgcactgctgcacgccgaccgggacggcgccctg
gtcaacctgatgaacgtcacccccgacggcgactaccagacctacaaggccaacgacggc
ggctatgtgcggcagcacttcttcggccgcgacccacgcaccaaggcgctggtcgagaac
ctgtccgatcaggacatctggcacctcaagcgcggcgggcatgactaccgcaaggtctac
gccgcctaccgcgcggccgtcgagcaccagggtcagccgacggtgatcctggccaagacc
atcaagggctacagcctcggcagctacttcgccggccgcaacgccacccaccagatgaag
aagttccgcccgcaagacctcaaggacttccgcgacgagatgcgaatccccatctccgac
gccgagatcgaggagaacccgtacctgccgccgtactaccaccccggcgaggacgcaccg
gagatccgctacctgctcgaccgccgccgcgccctgggcggtttcgtcccgcagcgccgc
acccgggcccgcgcgctgaccctgccgggccccgaggcgtacgcggcggtcaagaaaggg
tcggggacccaagaggtcgccaccaccatggcgaccgtgcgggtgttcaaagagttgttg
cgcgacaaggaaataggcacccgactggtcccgatcatccccgacgaggcccgcaccttc
gggatggactcctggttcccgtcgttgaagatctacaaccgcaacgggcagctctacacc
tcggtcgacgccgagttgatgctggcctacaaggaaagcgaagtcggccagatcctgcac
gagggcatcaacgaggccggctcgacggcgtcgttcaccgcggtcggcacgtcgtacgcc
acccacgacgagccgatgatcccgatctacatcttctactcgatgttcggcttccagcgc
accggcgacagcctctgggccgccgccgatcagatggcgcgcggtttcatcctcggcgcc
accgccggacgcaccacgctgaccggtgagggcctgcagcacgccgacgggcactcgctg
ctgctggcggccaccaacccggcggtggtctcctacgatcccgcgttcgccttcgaggtc
gcccacatcatcgaaagcggcctgcaacgcatgttcggggagaacccggagaacgtgtat
ttctacgtcaccctctacaacgagccctatattcagcccgccgagcccgacggcttcgac
gctgaagacgtcgccggcctgctgcgcgggatctaccgctaccagaaggccgcggagccg
aagtcccatgccgcccagatcctcgcctccggggtgtcgatgcccgaggcgctgcgcgcc
gccgagctgctggccgccgactgggatgtggccgccgacgtgtggtcggtgaccagctgg
ggtgagctcaaccgcgacggcgtggcactcgagcgcgagcgcctgcgtcaccccgagcgc
ccggccggcgagccgtacgtgacgcgggcgctcgccgacgccgccggcccggtcgtcgcg
gtgtcggactggatgcgcgcggtacccgagcagatccggccctgggtgccgggcaccttc
gtcacgctgggcaccgacggcttcggcttctccgacacccggaccgccgcgcggcgctac
ttcaacaccgacgcggagtcggtggccgtggcggtactggccgccttggcccgcgacggt
gccatcgacgcgtcgatcccggcgaccgccgccgaccggtaccagatcgacgatgtgatg
gccgccccggagcagacgtcggactcgggcgtggcttag
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