Methylobacterium nodulans: Mnod_7191
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Entry
Mnod_7191 CDS
T00839
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mno
Methylobacterium nodulans
Pathway
mno00010
Glycolysis / Gluconeogenesis
mno00020
Citrate cycle (TCA cycle)
mno00620
Pyruvate metabolism
mno00785
Lipoic acid metabolism
mno01100
Metabolic pathways
mno01110
Biosynthesis of secondary metabolites
mno01120
Microbial metabolism in diverse environments
mno01200
Carbon metabolism
mno01210
2-Oxocarboxylic acid metabolism
Module
mno_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mno00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Mnod_7191
00020 Citrate cycle (TCA cycle)
Mnod_7191
00620 Pyruvate metabolism
Mnod_7191
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Mnod_7191
Enzymes [BR:
mno01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Mnod_7191
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Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
ACL61931
UniProt:
B8IKE6
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All DBs
Position
7276567..7279236
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AA seq
889 aa
AA seq
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MERSRDLDTRDPDPIETREWLDSLDGVLEVEGPDRAHFLIEQVIEEARKKGAPVPYSANT
AYLNTIPVEAQPRHPGDRAIEHRIRSAIRWNAIALILRANKESSELGGHIASFQSAATLY
DTGFMHFWRAASETHGGDLIYIQGHSSPGIYARAYLEGRLTEEQLLNFRQEVGGQGLSSY
PHPWLMPDFWQFPTVSMGLGPLMAIYQARYLRYLHHRGLADTDGRKVWAFMGDGEMDEPE
SLGAISLASREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEANFRGAGWNVIKVLWGSG
WDQLLARDTSGMLARLMAECVDGEYQDFKSKNGAYIREHFFGRYPETKALVADWSDEDIW
RLTRGGHDPSKVYAAYDAAVKHKGQPTVILAKTVKGYGMGEAGEGQNITHQQKKMGEAVL
KQFRDRFQIDLSDEQIGGIPFIRFPEGSPEHRYLMARRQALGGPLPARRQKSQSLAVPPL
SAFEAQLKETAGREISTTMAFVRVLNTLLRDKEIGKRIVPIVPDESRTFGMEGMFRQFGI
FSQVGQLYRPEDANQLMYYKEDKTGQMLQEGINEAGAMSSWIAAATAYSHSDAPTIPFYI
YYSMFGFQRVGDLAWAAGDLRARGFLIGGTAGRTTLNGEGLQHEDGHSHLISATIPNCIS
YDPTFSYEVAVIVQDGLRRMYAEQEDVFYYITLMNENYAHPGMPEGAEAGILKGMYLFRE
GQGSGPRVQLLGSGTILREVIAGAELLQQDFGIAADIWSCPSFTELRREAMAVERWNLLH
PTETPKKSYVETCLSGRSGPVIAATDYMRLFADQIRPFVPGRYRVLGTDGFGRSDYRVRL
RDFFEVDRRWVAVAALKSLAEDGKVPAAKVAEAIAKYGIDPAKPAPWTV
NT seq
2670 nt
NT seq
+upstream
nt +downstream
nt
gtggaacgcagccgcgatctcgacacgcgcgatcccgatccgatcgaaacccgcgaatgg
ctcgactccctcgacggcgtgctggaggtggagggtcccgaccgggcgcatttcctcatc
gagcaggtcattgaggaggcccgcaagaagggcgcgccggtcccctattccgccaacacc
gcctatctcaacaccatccccgtcgaggcccagccccgccacccgggcgaccgggcgatc
gagcaccgcatccgctccgccatccgctggaacgccatcgcgctcatcctgcgggccaac
aaggaatcctccgagctcggcggccacatcgccagcttccagtcggccgccaccctctac
gacaccggcttcatgcatttctggcgcgccgccagcgagacccacggcggcgacctgatc
tacatccagggccattcctcgccgggcatctatgcccgcgcctatctggaggggcggctc
accgaggagcagctgctcaacttccgccaggaggtcgggggccagggtctctcctcctat
ccgcatccctggctgatgccggacttctggcagttccccaccgtctcgatggggctcggg
cccctgatggcgatctatcaggcccgctacctgcgctacctgcaccaccggggcctcgcc
gacaccgacggccgcaaggtctgggccttcatgggcgacggcgagatggacgagcccgag
tccctcggcgccatctccctcgcctcgcgggaaaaactcgacaacctgatcttcgtggtg
aactgcaacctgcagcgcctcgacgggccggtgcgcggcaacggcaagatcatccaggag
ctcgaggccaatttccgcggcgcgggctggaacgtcatcaaggtgctgtggggctcgggc
tgggaccagcttctggcccgcgacacctccggcatgctggcccgcctgatggcggagtgc
gtcgacggcgagtaccaggacttcaagtccaagaacggcgcctatatccgcgagcacttc
ttcggccgctaccctgagaccaaggcgctggtcgccgactggagcgacgaggacatctgg
cggctgacccgcggcggccacgatccgagcaaggtctatgcggcctacgacgcggccgtg
aagcacaagggccagcccaccgtcatccttgccaagaccgtgaagggctacggcatgggc
gaggcgggcgagggccagaacatcacccaccagcagaagaagatgggcgaggcggtcctc
aagcagttccgcgaccgcttccagatcgacctctcggacgagcagatcggcggcatcccg
ttcatccgcttccccgaaggcagccccgagcaccgctacctgatggcccgccgccaggcg
ctcggcggcccgctgccggcccggcggcagaaatcgcagagcctcgctgtcccgccgctc
tcggccttcgaggcgcagctcaaggagacggcgggccgcgagatctccaccaccatggcc
ttcgtgcgggtgctcaacacgctcctgcgcgacaaggagatcggcaagcgcatcgtgccg
atcgtgcccgacgagagtcgcaccttcggcatggagggcatgttccgccagttcggcatc
ttcagccaggtcggccagctctaccggcccgaggacgccaaccagctgatgtactacaag
gaggacaagaccggtcagatgctccaggagggcatcaacgaggccggcgccatgtcgtcc
tggatcgcggcggcgaccgcctattcgcattccgacgcgccgacgatcccgttctacatc
tactactcgatgttcgggttccagcgggtcggcgacctcgcctgggcggcgggcgacctc
agggcgcggggcttcctgatcggcggcacggccgggcgcaccacgctcaacggcgagggt
ctgcagcacgaggacggccacagccacctgatctcggccaccatccccaactgcatctcc
tacgacccgaccttctcgtacgaggtcgcggtgatcgtgcaggacggcctgcggcggatg
tatgccgagcaggaggacgtcttctactacatcaccctgatgaacgagaactacgcccat
ccgggcatgccggagggggcggaagcgggcatcctcaaagggatgtacctgttccgcgaa
gggcagggttcggggccgcgggtgcagctcctcggctcgggcaccatcctgcgcgaggtg
atcgccggggcggagctgctgcagcaggatttcgggatcgcggcggatatctggtcctgc
ccgagcttcaccgagctgaggcgcgaggcgatggccgtggagcgctggaacctgctgcac
ccgaccgagacgccgaagaagtcctatgtcgagacctgcctgtcgggccgctccggcccg
gtgatcgcggccaccgactacatgcggctcttcgccgaccagatccgtcccttcgtgccc
ggccgctaccgggtgctgggcacggacgggttcggccgctccgactaccgggtgcgcctg
cgcgacttcttcgaggtcgaccggcgctgggtggcggtggcggcgctgaagagcctcgcc
gaggacggcaaggtgccggcggccaaggtggcggaggcgatcgccaagtacggcatcgat
ccggccaagcccgccccctggacggtgtga
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