Mustela nigripes (black-footed ferret): 132003498
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Entry
132003498 CDS
T09425
Symbol
FASN
Name
(RefSeq) fatty acid synthase
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00061
Fatty acid biosynthesis
mnp01100
Metabolic pathways
mnp01212
Fatty acid metabolism
mnp04152
AMPK signaling pathway
mnp04910
Insulin signaling pathway
mnp04936
Alcoholic liver disease
Module
mnp_M00082
Fatty acid biosynthesis, initiation
mnp_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
132003498 (FASN)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
132003498 (FASN)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
132003498 (FASN)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
132003498 (FASN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
mnp01004
]
132003498 (FASN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mnp04147
]
132003498 (FASN)
Enzymes [BR:
mnp01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
132003498 (FASN)
Lipid biosynthesis proteins [BR:
mnp01004
]
Fatty acid synthase
Animal type
132003498 (FASN)
Exosome [BR:
mnp04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
132003498 (FASN)
Exosomal proteins of breast milk
132003498 (FASN)
Exosomal proteins of colorectal cancer cells
132003498 (FASN)
Exosomal proteins of bladder cancer cells
132003498 (FASN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
Thioesterase
KR
Ketoacyl-synt_C
KAsynt_C_assoc
FAS_pseudo-KR
ADH_zinc_N_2
ADH_zinc_N
PKS_DH_N
Methyltransf_12
PP-binding
Methyltransf_23
adh_short
Methyltransf_11
Methyltransf_25
DUF7080
PS-DH
Thiolase_N
Methyltransf_31
Motif
Other DBs
NCBI-GeneID:
132003498
NCBI-ProteinID:
XP_059234986
LinkDB
All DBs
Position
16:855061..872700
Genome browser
AA seq
2518 aa
AA seq
DB search
MEEVVIAGMSGKLPESDNLQEFWTNLIGGIDMVTDDDRRWKAGLYGLPRRSGKLKDLSKF
DASFFGVHPKQAHTMDPQLRLLLEATYEAILDGGINPASLRGTHTGVWVGVSGSEASEAL
SRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLMALQNAYQAIHSGQC
PSAIVGGINILLKPNTSVQFMKLGMLSPEGVCRSFDESGSGYCRAEAVVVMLLTKKSLAR
RVYATILNAGTNTDGCKEQGVTFPSGEAQEQLIRSLYEPAGLAPESLEYIEAHGTGTKVG
DPQELNGIDRALCTTRRDPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFC
SPNPEIPALREGRLQVVDRPLPVRGGIVAINSFGFGGSNVHVVLRPNSRPPSPSTPHVTL
PRLLRASGRTAEAVRCLLEQGHQHHRDPAFVSMLNDIAGSPPAAMPFRGFTMLGVQDGGL
EVQEVPQLPPGPRPVWFICSGMGTQWHGMGSSLMRLHGFRESILRSDEVVKPLGLQVSEL
LLSKDETTFDDLVHAFVSLTAIQIALIDLLTSMGVRPDGIIGHSLGEVACGYADGCLTRE
ETILTAYWRGQCIKEASIPPGAMAAVGLSWEECKQRCPPGIVPACHNSEDTVTISGPQAE
MVAFLEQLKEEGVFAKEVRTGGMAFHSYFMEAIAPTLLQALKKVIREPRPRSARWLSTSI
PEAQWQGSLARTSSAEYSVNNLVSPVLFQEALYHVPEHAVVLEIAPHALLQAVLKRGLKS
SCTIVPLMKKDQTDNLEFFLRSVGRLHLLGIDANPNGLYPPMEVPVPRGTPLISPHIKWD
HSQTWDVPAAGDFPSGSSGSSAATVYSIDTSPESPDHYLVDHCIDGRVLFPATGYLCLVW
KTLARSLSQNMDDLPVVFEGVTLHQATILPKTGTVALEVRLLEASRTFEVSENGNLIVSG
KVYQWEDPDPKLFDSQDGPDPTDPTAAFCLSQGDVYKELRLCGYDYGPHFQGVLEANLEG
NAGQLLWKDNWVTFLDAMLQLSILGAAQRSLRLPTRIISLHIDPATHRRKVYSLKGQAQV
ADVVVSSCLNSTVAGGAHISGLHASVAPRRQQEQLAPVLEKFCFTPHVEGGLLAGDTALQ
EELQLCRGLAQALQTKVAQQGLKMVVPGLDGAQVPREPPQQGLPQLLAAACQLQLNGSLQ
MELSQLLAQQRPLLHNDPLLCGLLDAPALKACVDTSLENLTSLRMRVVEVLAGDGCLYSR
IPLLLSTQPMLQLDYTATDRHPQALEAAQAKLQEYNLTQEQWDPAGPVPSSLGPADLLVC
NCAVATLHDPATALSNMAAALKEGGFLLLHTLLRGHPLGETVAFLTCPEPQRGQQSLLSQ
DEWEGLFAQAPLRLVALKRSFYGSALFLCRRPAPQGSPIFLPVEDTSFRWVDSLKSVLAD
NTSRPVWLTAVSCPTSGVVGMVNCLRREPGGQRVRCILVSNLSSTSPTPKMDPGSSELQK
VLQGDLVMNVYRDGAWGAFRHFPLEHGLPEEQTEHAFVNVLTRGDLSSIRWVCSPLRHTQ
PTDPSVHLCTVNYASLNFRDIMLATGKLSPDAIPGKWSSRDCMLGMEFSGRDASGKRVMG
LVPAEGLATSVLLSEDFLWDVPSSWTLEEAASVPVVYTTAYYSLIVRGRMQRGETVLIHS
GSGGVGQAAIAIALSLGCRIFTTVGSAEKRAYLQARFPQLSETSFANSRDTSFEQHVLRH
TAGKGVDLVLNSLAEEKLQASVRCLAVHGRFLEIGKFDLSNNHQLGMAVFLKNVTFHGIL
LDSLLDDGSSGWREVATLLRAGIRDGVVRPLKCTTFPKHRVEDAFRFMAQGKHIGKVVVQ
VLKEEPEAGPQVPRPTLMTAVSKTFCPAHKSYIITGGLGGFGLELAHWLVLRGAQKLVLT
SRSGIRTGYQAKQVREWRRQGVQVLVSTSNASSLDGARSLIAEATQLGPVGGVFNLAVVL
RDAVLENQTPEFFQDVNKPKYSGTVNLDRVTRAACPELDYFVAFSSVSCGRGNAGQTNYG
FANSTMERVCERRRHDGLPGLAVQWGAIGDVGLILESMGSNDTVISGTLPQRMSSCLGVL
DFFLSQPYPVLSSFVLAEKKAATQGDSSAQQDLMKAVAHILGIRDLATINLDSTLADLGL
DSLMGVEVRQMLEREHDLLLSMRDIRQLSLRKLQELSSKGGPAKELENAMPKNSSLAHQQ
AQPNLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSVTVFHSLAARLSIPTYGLQCT
RAAPLDSIQSLAAYYIECIRQVQAEGPYRIAGYSYGACVAFEMCSQLQAAQPGPAPAHNS
LFLFDGSHSYVLAYTQSYRAKMTLGCEAEAEAEAMCFFVQQFVDMEHDRVLEALLPLRGL
EERVAATVDLIVRSHAGLDRRQLSFAAHSFYHKLRAAEQYAPRATYHGNVTLLRAKTSSL
YGEGLGADYNLSQVCDGKVSVHVVEGDHRTLLEGSGLESILSIIHSTLAEPRVSVREG
NT seq
7557 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggtggtgatcgctggtatgtccgggaagctgcccgagtcggacaacttgcag
gagttctggaccaatctcatcggcggcatagacatggtgacagacgatgacaggaggtgg
aaggctgggctctacggcctgcccaggcggtccggcaagctgaaggacctgtccaagttc
gacgcctccttcttcggggtgcacccaaagcaggctcacacgatggacccccagctgcgc
ttgctgctggaggccacctacgaggccatcctggatggaggcatcaacccagcgtcactc
cgagggacacacaccggtgtctgggtgggcgtgagcggctccgaggcctcggaggccctc
agccgagaccccgagactctcctgggctacagcatggtgggctgccagcgggccatgatg
gccaaccgtctctctttcttctttgattttaaagggcccagcattgctctggacacggcg
tgctcgtctagcctcatggctctgcagaacgcgtaccaggccatccacagcgggcagtgc
cccagtgccatcgtgggcggcatcaacatcctgctcaagcccaacacgtccgtgcagttc
atgaagctgggcatgctgagccccgagggcgtctgcaggtccttcgatgagtctgggagc
ggctattgccgcgcagaggcagtggtggtcatgctgctgaccaagaagtccctggcccgg
cgtgtgtacgccaccatcctgaatgccggcaccaacaccgacggctgcaaggagcaaggt
gtgaccttcccctctggggaggcgcaggagcagctcatccgctccctgtacgagccagcc
gggctggccccagagtccctggagtacattgaagcccatggcacgggcaccaaggtgggt
gacccccaggagctgaacggcattgaccgagccctttgcaccacccgccgggacccgctg
ctgatcgggtccacaaagtcgaacatggggcacccagagcccgcctcagggctggcggca
ctggccaaggtgctgctgtccctggaacacgggctctgggcccccaacctccacttctgc
agcccgaaccctgagatccccgccctccgggaagggcggttgcaggtggtggaccggccc
ctgcctgtccgcggcggcatcgtggccatcaactccttcggctttggaggctccaacgtg
cacgtcgtcctcagacccaactcacggccgccctcgccatccaccccgcacgtcaccctg
ccccgtctgctgcgggccagcgggcgcactgcggaggccgtgcgttgcctgctggagcag
ggtcaccagcaccaccgggacccggccttcgtgagcatgctcaacgacatcgcaggcagc
ccccccgccgccatgcccttccggggcttcacgatgctgggggtgcaggacggcggcctg
gaggtgcaggaggtgccgcagctgccccccggcccgcgtccggtctggttcatctgctcc
gggatgggcacgcagtggcacggaatggggtcgagcctcatgcgcctgcacggcttccgg
gagtccatcctgcgttccgacgaggtggtgaagcccctgggtctgcaggtgtctgagctg
ctcctgagcaaggacgagaccacctttgacgacctcgtccacgccttcgtcagtctcacc
gccatccagatcgctctcatagacctgctgacctcaatgggcgtgcggccggacggcatc
attgggcactcgctgggggaggtggcctgcggctacgccgacggctgtctcactcgggag
gagaccatcctcaccgcctactggcggggccagtgcatcaaggaggccagcattcctccg
ggagccatggcggccgtgggcctgtcctgggaggagtgtaagcagcgctgcccccccggc
atcgtgcccgcctgccacaactccgaagacacggtgaccatctccggaccacaggccgag
atggtcgccttcttggagcagctgaaggaggagggtgtgtttgccaaggaggtgcggacg
ggcggcatggccttccactcctacttcatggaggccatcgcccccacgctgctgcaggcg
ctcaagaaggtgatccgggagcctaggccccgctcagcgcgctggctcagcacctccatc
cccgaggcccagtggcagggcagcctggcccgcacgtcctccgcggagtacagcgtcaac
aacctcgtgagcccggtgctgttccaggaggcgctctaccacgtgcccgagcacgccgtg
gtgctggagatcgccccgcacgcgctgctgcaggccgtcctgaagagaggcctcaagtct
agctgcaccatcgtccccttgatgaagaaggaccagacggacaacctggagttcttcctc
aggagcgtgggcaggctgcacctgctgggcattgatgccaaccccaacggcctgtatcca
cccatggaggtcccggtgccccgggggacccccctcatctccccccacatcaagtgggac
cacagtcagacctgggacgtgcctgcagccggggacttccccagcggctccagcggctcc
tccgcggccaccgtctacagcattgacaccagtcctgagtcccccgaccactacctggtg
gaccactgcatcgacggccgagtactcttccctgccaccggctacctgtgcctggtgtgg
aagacgctggcgcgctccctgagccaaaacatggatgacctgcctgtggtgtttgaggga
gtgacgttgcaccaagccaccatcctgcccaagaccgggaccgtggctctggaagtgcgg
ctgctggaggcttcccgcaccttcgaggtgtctgagaacggcaacctgatcgtgagcggg
aaggtgtaccagtgggaggaccccgaccccaagctcttcgacagccaggatggcccggat
cccacggaccccacggctgcgttctgcctgtcccagggggacgtgtataaggagctgcgg
ctgtgcggctatgactatggcccccatttccagggtgtcctggaggccaacctcgaaggc
aacgcaggccagctgctgtggaaggacaactgggtgacctttctggacgccatgctgcag
ctctccatcctgggggcggcccagcgcagcctgcgcctgcccacccgcatcatctccctg
cacatcgaccctgccacgcaccggcggaaggtgtactcgctcaagggccaggcccaagtg
gccgacgtggtggtgagcagctgcctgaatagcacggtggccgggggcgcccacatctcg
ggcctgcatgcgtccgtggccccgcggcggcagcaggaacagctggcccccgtcctggag
aagttctgcttcaccccacacgtggagggggggctcctggccggagacacggccctgcag
gaggagctgcagctgtgcagggggctggcacaggccctgcagaccaaggtggcccagcag
gggctgaagatggtggtgccgggactggacggggctcaggtcccccgggagcccccgcag
cagggcctgccgcagctgctggccgccgcctgtcagctccagctcaacgggagcttgcag
atggagctgagccagctcctggcccagcagaggcccctgctgcacaacgacccgctgctc
tgcggcctgctcgacgccccggcgctcaaggcctgcgtggacacctccctggagaacctg
accagcctccgcatgcgcgtcgtcgaggtgctggctggcgacggctgcctctactcccgc
atcccactgctgctcagcacccagcccatgctccagctggactacacggccacggaccgc
cacccgcaggccctggaggccgcccaggccaagctgcaggagtacaacctgacccaggag
cagtgggaccctgcgggccccgtccccagcagcctgggcccggctgacctgctggtgtgc
aactgtgccgtggccacactccatgacccagccacggccctcagcaacatggcggctgct
ctcaaggagggtggcttcctgctgctgcacaccctgctcagaggacaccccctgggggag
accgtcgccttcctcacctgcccggagccccagcgaggccagcagagcctcctgagccag
gatgagtgggaggggctgtttgcccaggcgcccctgcgtctggtggccctgaagaggtcc
ttctacggctccgcgctcttcctgtgccgccggccggcccctcagggcagccccatcttc
ctgcccgtggaggacaccagcttccgctgggtggactccctgaagagcgtcctggcagac
aacacctcccgacccgtgtggctgacggccgtcagctgccccacctcgggcgtcgtgggc
atggtgaactgtctccgccgggagcccggcgggcagcgggttcgatgcatcctggtgtcc
aacctcagcagcacgtcccccacccccaagatggacccaggctcctcggagctgcagaag
gtgttacagggggacctcgtgatgaatgtctaccgcgacggggcctggggggccttccgc
cacttcccactggagcacggcctgccggaggagcagaccgagcacgcctttgtcaacgtt
ctcacccggggggatctctcctccatccgctgggtctgctcgcccctgcgccacacccag
cccactgaccccagtgtgcatctctgcaccgtcaactacgcctccctcaacttccgagac
atcatgctggctacgggcaagctgtcccccgacgccatcccagggaaatggtcctcccgg
gactgtatgctgggcatggagttctctggccgggacgccagtggcaagcgcgtgatgggg
ctcgtgccggctgaaggcctggccacctccgtcctgctgtcggaggacttcctgtgggat
gtgccgtccagctggaccctagaggaggccgcgtctgtgcccgtggtgtacaccaccgcc
tactactcgctgatcgtgcggggacgcatgcagcgcggggagacagtcctcatccactcg
ggctccggcggcgtgggccaggccgccatcgccatcgccctgagcctgggctgccgcatc
ttcaccaccgtggggtccgccgagaagcgggcgtatctccaggccaggttcccccagctc
agcgagaccagctttgccaactcccgggacacgtccttcgaacagcacgtgctacggcac
acggccgggaagggtgtcgacctggttctgaactctctggcggaggagaagctgcaggcc
agcgtgcgctgcctggccgtgcacggccgcttcctggagatcggcaaattcgacctttcc
aacaaccaccagctgggcatggctgtcttcctgaagaacgtgaccttccacggcatcctg
ctggactcgctcctggacgacgggagcagcggctggcgggaggtggcgaccctgctgcgg
gcgggcattcgggacggcgtggtgcggcccctcaagtgcaccacgttccccaagcaccgg
gtggaggacgccttccgcttcatggcccaggggaagcacatcggcaaagtggtggtgcag
gtgctcaaggaggagccagaggcagggccacaggtgcccaggcccacactgatgaccgcg
gtgtccaagaccttctgcccagcccacaagagctacatcatcacgggcggcctgggcggc
ttcggcctggagctggcccactggcttgtgctgcgcggcgcccagaagctcgtgctgacc
tctcgctccgggatccgcacaggctaccaggccaagcaagtccgcgagtggagacgccag
ggcgtgcaggtcctggtgtccaccagcaacgccagctctctcgacggggcccggagcctc
atcgcggaggccacgcagctggggcctgtgggcggcgtcttcaacctggctgtggtcctg
agagacgccgtgctagagaatcagactcctgagttcttccaggacgtcaacaagcccaag
tacagtggtaccgtgaacttggacagggtgacccgggcggcgtgccccgagctggactac
ttcgtggccttctcgtccgtgagctgcgggcgcggcaacgctggccagaccaactacggc
ttcgcgaactcgaccatggagcgtgtgtgcgagaggcgccgccacgacgggctcccaggc
ctcgccgtgcagtggggcgccatcggtgacgtgggcctcatcctggagtcgatgggctcc
aacgacacggtcatcagcgggacgctgcctcagcggatgagctcctgcttgggggtgctg
gatttcttcctgagccagccctaccccgtcctgagcagctttgtgctggctgagaagaag
gctgccacccagggagacagcagcgcccagcaggacctcatgaaggccgtggcccacatc
ctgggcatccgagacttggccaccatcaacttggacagcacgctggcagacctgggcctg
gactcgctcatgggcgtcgaggtgcggcagatgctggagcgtgagcacgacctgctgctg
tccatgcgggacatccggcagctctcgctccgcaagctgcaggagctttcttcaaagggc
ggcccggcgaaagagctggagaacgccatgcccaagaacagcagcctggcccatcagcag
gcccagccgaacctgagcaccctgctggtgaacccggagggccccaccttgacgcggctc
aactcggtgcagagctctgagcgaccgctgttcctggtgcaccccatcgagggctccgtc
accgtgttccacagcctggctgccaggctcagcatccccacctacggcctgcagtgcacc
cgagccgcgcccctggacagcatccagagtctggccgcctactacatcgagtgcatccgc
caggtgcaggccgaggggccctaccgcatcgccggctactcgtacggggcctgcgtggcc
ttcgagatgtgctcacagctgcaggctgcgcagcccggccctgcccccgcacacaacagc
ctcttcctgttcgacggctcgcactcctacgtgctggcctacacgcagagctaccgcgcc
aagatgaccctgggctgcgaggccgaggccgaggccgaggccatgtgcttctttgtgcag
cagttcgtggacatggagcacgacagggtgctcgaggcgctgctgcccctccggggcctg
gaggagcgcgtggcagccaccgtggacctgattgtgcgcagccatgccggcctggaccgc
cggcagctgagctttgccgcccactccttctaccacaagctgcgtgcggcggagcagtac
gcgccgcgggccacctaccacggcaacgtgacgctgctgcgcgccaagaccagcagcctg
tacggcgagggcctgggcgccgactacaacctgtcccaggtgtgcgacggcaaggtgtcc
gtgcacgtggtcgagggtgaccaccgcacgctgctggagggcagcggcctggagtccatc
ctcagcatcatccacagcaccctggccgagccccgcgtcagcgtgcgggagggctag
DBGET
integrated database retrieval system
