Mustela nigripes (black-footed ferret): 132007037 Help Entry 132007037         CDS       T09425                                  Symbol IRS4 Name (RefSeq) insulin receptor substrate 4   KO K17446   insulin receptor substrate 4 Organism mnp  Mustela nigripes (black-footed ferret) Pathway mnp04022   cGMP-PKG signaling pathway mnp04068   FoxO signaling pathway mnp04081   Hormone signaling mnp04140   Autophagy - animal mnp04152   AMPK signaling pathway mnp04211   Longevity regulating pathway mnp04213   Longevity regulating pathway - multiple species mnp04910   Insulin signaling pathway mnp04920   Adipocytokine signaling pathway mnp04923   Regulation of lipolysis in adipocytes mnp04930   Type II diabetes mellitus mnp04935   Growth hormone synthesis, secretion and action mnp05010   Alzheimer disease Brite KEGG Orthology (KO) [BR:mnp00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     132007037 (IRS4)    04022 cGMP-PKG signaling pathway     132007037 (IRS4)    04152 AMPK signaling pathway     132007037 (IRS4)   09133 Signaling molecules and interaction    04081 Hormone signaling     132007037 (IRS4)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     132007037 (IRS4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     132007037 (IRS4)    04923 Regulation of lipolysis in adipocytes     132007037 (IRS4)    04920 Adipocytokine signaling pathway     132007037 (IRS4)    04935 Growth hormone synthesis, secretion and action     132007037 (IRS4)   09149 Aging    04211 Longevity regulating pathway     132007037 (IRS4)    04213 Longevity regulating pathway - multiple species     132007037 (IRS4)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     132007037 (IRS4)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     132007037 (IRS4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH_11 PH PH_8 Motif Other DBs NCBI-GeneID:  132007037 NCBI-ProteinID:  XP_059241179 LinkDB All DBs Position X:38807127..38810909 Genome browser AA seq 1260 aa AA seqDB search MASGSFARDQATRRLRAAAAATAAALSAVGTTPLLSSGIPTALIGTGSSCPGAMWLSTAT SSRSDSESDEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH SVRAAAAAAAAAASGAAVPALIPPRRVITLYQCFSVSQRADAKYRHLIALFTQDEYFAMV AENESEQESWYLLLSRLILESKRRRCRTPGALPDGEPARPAAAAAAAEPPFYKDVWQVIV KPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRS TVIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYTISIGAHLLNLLSARR HLDTLPREPGGWLRRSRVEQFYHFRAIGDREDEMPLTRRYLTPSEPVPTSRRARLHLPRA RRSRRAISVPPSYFRRLPSSPVRVLYPAEVPNHRAGLSPEASGSGNSGEEDSPQGQEAQE GNGGDYMPMNRWGSGNGQGSGSGQGSSGQGSSSQGSGGSQCSGGGPGSSGGQGSGSQGAG GNQRSGDGQSTAGGQGSGSGQGASGGGHGSSGGRGPGDGHGSGGGKSHGGGKGSGSGKIS EGNGERGKSLKKRSYFGKLTQSKQHMPPPPPPPPPAGATGSKGKSGGRFRLYFCADRGTP KERKEAKELKDLETLEGAAQGPHRARAFDEDEDDPYVPMRPGVAAPPPSSSDYMPMAPQN FAPSKMHHSRSPFEDSRGYMMMFPRVSSPPAPSPAKEADPEKEDESKDNDSESDYMFMAP GAGAIPKKPPNPQGGSSSKNWSSYVSLPSPFQGSPLGQSDHSEYVPMLPGKFPGKGLDKE ASSSGGPKDAVSKPSAEGSFSKRGDGASLTKPSDDGPPKNKAKRPNSLSFITKGNKIKPK SQKPTREQRGADSSHDYVNIDFTKRESNVPAPFIHGLPGSWGIIAGPRRSAFSNYVNVEF GLPFPNQAHRLSNLLRAIPGANPLYLEGARWPLVPLPPNSAGGSANEEEGDYIEVIFNPA MTPAVPFGDRAIRYDPKTGRIYVVDPFSECCMDISLSPGRCFEPPPVARLLQEEQQQPER RRPQSRSQSFFGSARAAVSAFSTDSLERDLSSPLAAAAAASAAAPALALSQAFAAASALV VAPGVGAAARGLEAAAGFNSASARWFQPVAGAAAAAEAVRGAPNVAGGSNLRAPNPFADL AGGENGAAAAAPRPPPRRPVPRPPGREDPDEDDDDDDDIYVRMDFARPDNKKFDSPRRGG NT seq 3783 nt NT seq  +upstreamnt  +downstreamnt atggcgagtggctccttcgctcgcgaccaagcgacgaggagactgagggctgctgcagcg gcaacagcggcggctctctctgcggtggggaccaccccacttctttcctcgggcatccct accgcactcattgggaccgggtcgtcttgtccgggagccatgtggctctccacggccacc agctcccggtcagactcggagtctgatgaggaggacctccccgtcggggacgaagtctgc aaacgcggctaccttcggaagcagaagcacggccacaggcgctacttcgtgctcaaactc gagacagccgacgccccggctcggctggaatactatgaaaacgccaggaagttccggcac agtgtccgcgccgcggcagcggcggcggcggcggctgcctccggagccgcggtccccgcg ctcatcccgccgcggcgcgtgatcaccctgtaccagtgcttctccgtgagccagcgagcc gacgccaaataccgacacctcatcgccctcttcacccaggatgagtacttcgccatggtg gccgagaacgagtcggagcaggagagctggtacttgctgctcagccgcctcatcctcgag agcaaacgccgccgctgccgcacgccgggcgcgctgccggatggggagccagcccggccg gcggctgcagcggcggcggccgagccacctttctacaaggatgtgtggcaggtaatagtc aaacccagggggctggggcacagaaaagagctgagcggcgtgttccggctctgtcttacc gacgaagaggtggtgttcgtgaggctgaacaccgaagtggccagcgtggttgtccagctc ttgagcatccgtcgctgcgggcactcggagcagtatttcttcttggaagtcggcaggtcc acggtcatcggccccggggagctctggatgcaggtcgatgactgtgtggtagcccaaaac atgcacgagctgtttctggagaagatgagagccctgtgtgcagatgagtaccgagcccgc tgccgcagctacaccatcagcatcggcgcccacctgttaaacctgctgtccgctaggagg cacctggacacgctgccgcgcgagcccggcggctggctgagaaggtcccgcgttgaacag ttttaccacttcagggccatcggtgacagggaagacgagatgcccctcaccaggcgctac ctgacacccagcgaacccgtgcccacctccaggcgagcaaggctgcacctgcctagagcg cgcaggtccaggagagcgatttcagtgcctcccagctattttcgccgcctcccatccagc ccggtacgtgtcctgtatcctgcagaagtcccgaaccacagagctggcctgtctcctgaa gcctctggatctggcaactctggggaagaagacagtccccaaggccaagaggctcaggaa ggaaacggaggtgactacatgcccatgaacagatggggctcgggcaacggccagggttcc ggaagtggccagggctcgagtggccaaggctccagtagccagggttcaggaggaagccag tgctctggcggggggccgggctccagtggtggccagggctcagggagccagggtgcagga ggaaaccagcggtcaggagatggccagagcactgcaggtgggcaaggctcgggcagtggc cagggagccagcggcggtggacatggctccagcggtgggcggggacccggagatggccat ggctcaggcgggggtaagagccacggagggggtaaaggttcaggaagtgggaaaatctcg gagggcaatggtgagcgtggaaaatctctgaagaaaaggtcctactttggcaaattaact caaagcaagcagcacatgccaccccctccccctccacctccaccggctggagcaactggt agcaaagggaagtctgggggaaggttccgactttacttttgcgctgacaggggaacccca aaagaacgcaaagaggccaaggagctcaaagacttagagacactggaaggtgcagctcag gggccccacagagccagagcttttgacgaagatgaggatgacccttatgtgccaatgagg ccgggggtggctgcccctcccccaagctccagtgactatatgccaatggctcctcaaaac ttcgctccttcaaaaatgcaccactctcgatcaccttttgaagattcaagagggtacatg atgatgtttcccagagtgagctcaccacctgccccaagtcccgcgaaagaggcagatcct gaaaaggaggatgagtcaaaggacaatgacagtgagagtgactatatgtttatggctcct ggagccggtgcaattccaaaaaaacccccaaatcctcagggtggctcttcctctaaaaac tggagctcttacgtttccctgccaagcccttttcagggctccccattgggacagagtgat cacagtgagtatgtaccaatgttacctggaaagttcccagggaagggcctagacaaggaa gcctcatccagcgggggccccaaagatgcagtttcaaagccttcagctgaggggtcattc tcaaagcgtggagatggggcgtcactgacaaagccttcagatgacggcccccccaagaac aaggctaaaagacctaacagcctctctttcatcacaaaaggaaataaaatcaagccaaaa tcacaaaagcccactcgtgaacagagaggagctgacagctctcatgactacgtcaacatt gacttcactaagagagagagcaatgtgccagccccctttattcacggactgccaggttcg tggggcatcattgctggccccagacggtcagccttttctaactatgtgaatgttgagttc ggactgccatttccaaaccaagcacacaggctctcgaatcttttaagagccattccaggt gccaaccccctttatctggaaggtgctaggtggccacttgtgcctcttcctcccaactct gcaggtggcagtgcgaacgaggaagagggtgactacattgaagtgattttcaatccagca atgacaccagccgtgccttttggtgacagggccattcgctatgatcccaaaacaggtcgc atctatgtggtcgacccattttcagagtgctgtatggacatttcgctctcccccggccgc tgtttcgagccaccacctgtagccaggctgctgcaggaagaacaacagcagccggagcga agacgcccgcaaagccgttcgcaaagtttctttgggtcggccagggccgcggtctcagct ttctcaaccgacagcctcgagagagacctctcgagccccttggccgcggccgctgctgct tcggcagctgcgcccgccttagccttgagccaggcgtttgccgccgcctctgccctcgtc gtggccccgggcgtcggggcagccgccaggggcttggaggccgccgcaggctttaactcc gcctccgcccgctggttccaacctgttgctggcgccgcggccgccgccgaagcggtcagg ggggccccaaacgtggccggtggctcgaacctgagagcccccaacccatttgcagaccta gctggcggtgagaacggggccgcagcggccgccccacgaccgccgccgcgccgcccggtg ccgagacccccggggcgagaggatcctgacgaagacgacgacgatgacgacgacatctac gtgagaatggactttgccagacctgacaacaagaagttcgactctccccgcagaggtggg taa

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