Mustela nigripes (black-footed ferret): 132011164
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Entry
132011164 CDS
T09425
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04062
Chemokine signaling pathway
mnp04151
PI3K-Akt signaling pathway
mnp04217
Necroptosis
mnp04550
Signaling pathways regulating pluripotency of stem cells
mnp04630
JAK-STAT signaling pathway
mnp04658
Th1 and Th2 cell differentiation
mnp04659
Th17 cell differentiation
mnp05161
Hepatitis B
mnp05162
Measles
mnp05166
Human T-cell leukemia virus 1 infection
mnp05169
Epstein-Barr virus infection
mnp05200
Pathways in cancer
mnp05203
Viral carcinogenesis
mnp05223
Non-small cell lung cancer
mnp05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
132011164 (JAK3)
04151 PI3K-Akt signaling pathway
132011164 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
132011164 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
132011164 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
132011164 (JAK3)
04659 Th17 cell differentiation
132011164 (JAK3)
04062 Chemokine signaling pathway
132011164 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132011164 (JAK3)
05203 Viral carcinogenesis
132011164 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
132011164 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
132011164 (JAK3)
05161 Hepatitis B
132011164 (JAK3)
05162 Measles
132011164 (JAK3)
05169 Epstein-Barr virus infection
132011164 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
132011164 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mnp01001
]
132011164 (JAK3)
Enzymes [BR:
mnp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
132011164 (JAK3)
Protein kinases [BR:
mnp01001
]
Non-receptor tyrosine kinases
JAK family [OT]
132011164 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
FERM_C_FAK1
SH2
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
132011164
NCBI-ProteinID:
XP_059245377
LinkDB
All DBs
Position
2:complement(13718686..13736347)
Genome browser
AA seq
1127 aa
AA seq
DB search
MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSYGDHSAEELCVWAAKA
SGILPVYHSLFALATEDLSCWFPPSHIFSVEDSSTQVLVYRLRFYFPNWFGLEKCHRFGL
RKDLASAVLDLPVLEHLFAQHRNDLVSGRLSVGLSLKEQGECLSLAVLDLARMAREQVQQ
PEEMLKTVSYKVCLPPDLRDLIQGLSFVTRKRIRRTVRRALRRVTACQADRHSLMAKYIM
DLERLDPARAVETFPVNLPGAAGGEDAKGLLRVAGDSGIAWSSGGQEALQPFCDFPEIVD
ISIKQAPCVGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLISDSRHFFC
KEVAPPRLLEEVAEQCHGPITLDFAINKLKTQGSRPGSYVLRRSPQDFDCFLLTVCVQTP
LGPDYKGCLIRCDPTGTFSLAGLGRPHSSLRELLAACWNGGLHVDGVALSLTFCCTPKPK
EKSNLIVVRRGCSPPTSSPLQTQSQGQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR
HEVVEGEARKTEVLLKVMNAKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSIMVQ
EFAHLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA
DGNLPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLLEPRTLGLEADKWGFGATVWEVFS
GIPIPISTLDPAKKLQFYKEQQQLPAPKWMELAMLIQQCMVYEAGQRPSFRAIIRDLNSL
ITSDYELLSDPTPGALTPRDGLWNGAQLYAYQDPTIFEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPDQQKDFQREIQTLKALHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLDANRLLLYASQICKVSQVGPLLVALECGPHARLQGMEYL
GSRRYVHRDLAARNILVESETHVKIADFGLAKLLPLDKDYYVVHKPGQSPIFWYAPESLS
DNIFSRQSDVWSFGVILYELFTYGNKSCSPSAEFLRMMGMMGCDRDVPALCCLLELLAEG
QRLPAPAACPGEVHELMKLCWASSPKDRPTFSALGPQLDALWSASRG
NT seq
3384 nt
NT seq
+upstream
nt +downstream
nt
atggcgcctccaagtgaggagacacccctgatccctcaacgttcctgcagcctctcatct
tcagaggcaggtgccctgcacgtgctgctgcctcctcggggccctggacccccacagcgc
ctatccttctcctatggagaccattcagctgaagagctgtgtgtttgggctgctaaggcc
agtggcatcctgcctgtgtaccactccctctttgccctggccacggaggacctgtcctgc
tggttccccccaagccatatcttctccgtggaggactcaagcacccaagtcctggtctac
aggctccgcttttacttccccaactggtttgggctagagaagtgccaccgcttcgggctg
cgcaaggacttggccagcgccgtccttgacctaccagtcctggagcacctcttcgctcag
catcgaaatgacctggtgagcggccgcctctccgtgggcctcagtctcaaggagcagggg
gaatgtctcagcctggcggtgctggacctggcccggatggcccgcgagcaggttcagcaa
cctgaggagatgctgaagactgtcagctataaggtctgcctgccccccgacctgcgcgac
ctgattcagggcctgagcttcgtgacgcggaagcgcatccggaggacggtgcgccgggcc
ctgcgccgtgtgaccgcctgccaggctgacaggcattcgctcatggccaagtacatcatg
gacctggagaggctcgacccggccagggcggtcgagaccttccccgtgaacctccccggg
gctgctggtggtgaggatgcgaaggggctgctccgagtggctggtgacagcggcatcgcc
tggagttcgggaggacaggaggccctccagcccttctgcgactttccagaaattgtggac
atcagcatcaagcaggctccgtgtgttggcccggccggggagcaccgcctggtcaccgtc
accaggacggacaaccagatcctggaggccgagttcccggggctgcccgccgcgttgtcc
tttgtggcgcttgtcgatggctacttccggctgatctccgactccaggcacttcttctgc
aaggaggttgcgccgccacggctgctggaagaagtggccgagcagtgccacggccccatc
accctggattttgccatcaacaaactcaagacccagggctcacgtcccggctcctacgtt
ctccgccgcagtccccaggattttgactgcttcctcctcactgtctgtgttcagaccccc
ctgggtcctgattacaagggctgcctcatccgctgtgaccccacaggaaccttctccctg
gctggcctcggccgtccccacagcagtcttcgagagctcttggcagcctgctggaatggt
gggctgcacgtggatggggttgcgctaagcctcactttctgctgcacccccaaacccaaa
gaaaagtccaacctcattgtggtacggaggggttgtagcccacccacatcatcccctctt
cagacccaatcccaaggccagctgagtcagatgacgtttcacaagatccctgctgacagc
ctggagtggcatgagaacctgggtcatggatcgttcaccaagatttaccggggttgtcgc
catgaggtcgtggagggggaggcccggaagacagaggtgctgctcaaagtgatgaatgcc
aagcataaaaactgcatggagtcatttctggaagctgcgagtctgatgagccaagtgtca
taccagcacctcgtgttgctccatggcgtgtgcatggctggagacagtatcatggtgcag
gaatttgcacacctgggagcgctggacacctacctgcgcaagtctggccacctggtgcca
gccagctggaagctgcaggtgatcaaacagctggcctatgccctcaactatctggaggac
aaaggcctcccccatggcaatgtctcagcccggaaggtgctccttgctcgcgaaggggct
gatgggaacctgcccttcatcaagcttagtgaccctggggtcagccctgctgtgctaagc
ctggagatgctcacagacaggatcccatgggtggcccctgagtgtctcctggagccccgg
acacttggcttggaagctgacaagtggggttttggtgccacagtctgggaggtgttcagc
gggatcccgatacccatcagcaccctggatcctgccaagaagcttcagttttataaagaa
cagcagcagctccctgcccccaagtggatggagctcgccatgctgatccaacagtgcatg
gtctacgaggcaggccagaggccctccttccgtgccattatccgcgacctgaacagcctc
atcacttcagattatgagctcctctcagaccccacacctggtgccttgacgccccgtgat
gggctatggaatggcgcccagctctacgcctaccaagaccctactattttcgaggagaga
cacctcaagtacatctcacagctgggcaagggcaactttggcagcgtggaactgtgccgc
tatgacccgctgggcgacaacacaggcgccctagtggcagtgaagcagctgcaacacagc
gggccagaccagcagaaggacttccagagggagatccagaccctcaaagccctccacagt
gacttcattgtcaagtaccgcggtgtcagctatggcccaggccgccagagcctgcggctg
gtgatggagtacctgcccagcggctgcctgagggacttcctacagcggcaccgcgcgcgc
ctcgatgccaaccgcctgctcctctacgcctcacagatctgcaaggtaagccaggttggg
cccctgctggttgcgctggagtgtggccctcacgctcgcctgcagggcatggagtacctg
ggctcccgccgctatgtgcaccgcgaccttgccgcgcgtaacatcctggtggagagcgag
acgcacgtcaagatcgccgacttcggcctcgccaagctgctgccgctcgacaaagactac
tacgtggtccacaagcccggccagagccccatcttctggtacgccccagagtctctctct
gacaacatcttctcgcgccagtcggacgtctggagcttcggggtcatcctgtacgagctt
ttcacctacgggaacaagagctgcagcccctcagccgagttcctgcggatgatggggatg
atgggatgtgatagagacgtcccggccctctgctgcctcctggaacttctggctgagggc
cagaggctgccggcgcctgctgcctgccctggtgaggttcatgagctcatgaagctgtgc
tgggcctctagcccgaaagaccgaccaacattcagtgccttgggccctcagctggacgca
ctatggagtgcgagccgggggtag
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