Mustela nigripes (black-footed ferret): 132013450 Help Entry 132013450         CDS       T09425                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism mnp  Mustela nigripes (black-footed ferret) Pathway mnp01524   Platinum drug resistance mnp04115   p53 signaling pathway mnp04210   Apoptosis mnp04215   Apoptosis - multiple species mnp04217   Necroptosis mnp04620   Toll-like receptor signaling pathway mnp04621   NOD-like receptor signaling pathway mnp04622   RIG-I-like receptor signaling pathway mnp04623   Cytosolic DNA-sensing pathway mnp04625   C-type lectin receptor signaling pathway mnp04657   IL-17 signaling pathway mnp04668   TNF signaling pathway mnp04932   Non-alcoholic fatty liver disease mnp04936   Alcoholic liver disease mnp05010   Alzheimer disease mnp05016   Huntington disease mnp05022   Pathways of neurodegeneration - multiple diseases mnp05132   Salmonella infection mnp05134   Legionellosis mnp05142   Chagas disease mnp05145   Toxoplasmosis mnp05152   Tuberculosis mnp05160   Hepatitis C mnp05161   Hepatitis B mnp05162   Measles mnp05163   Human cytomegalovirus infection mnp05164   Influenza A mnp05165   Human papillomavirus infection mnp05167   Kaposi sarcoma-associated herpesvirus infection mnp05168   Herpes simplex virus 1 infection mnp05169   Epstein-Barr virus infection mnp05170   Human immunodeficiency virus 1 infection mnp05200   Pathways in cancer mnp05203   Viral carcinogenesis mnp05416   Viral myocarditis mnp05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mnp00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     132013450 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     132013450 (CASP8)    04215 Apoptosis - multiple species     132013450 (CASP8)    04217 Necroptosis     132013450 (CASP8)    04115 p53 signaling pathway     132013450 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     132013450 (CASP8)    04621 NOD-like receptor signaling pathway     132013450 (CASP8)    04622 RIG-I-like receptor signaling pathway     132013450 (CASP8)    04623 Cytosolic DNA-sensing pathway     132013450 (CASP8)    04625 C-type lectin receptor signaling pathway     132013450 (CASP8)    04657 IL-17 signaling pathway     132013450 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     132013450 (CASP8)    05203 Viral carcinogenesis     132013450 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     132013450 (CASP8)    05161 Hepatitis B     132013450 (CASP8)    05160 Hepatitis C     132013450 (CASP8)    05164 Influenza A     132013450 (CASP8)    05162 Measles     132013450 (CASP8)    05168 Herpes simplex virus 1 infection     132013450 (CASP8)    05163 Human cytomegalovirus infection     132013450 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     132013450 (CASP8)    05169 Epstein-Barr virus infection     132013450 (CASP8)    05165 Human papillomavirus infection     132013450 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     132013450 (CASP8)    05134 Legionellosis     132013450 (CASP8)    05152 Tuberculosis     132013450 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     132013450 (CASP8)    05142 Chagas disease     132013450 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     132013450 (CASP8)    05016 Huntington disease     132013450 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     132013450 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     132013450 (CASP8)    05416 Viral myocarditis     132013450 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     132013450 (CASP8)    04932 Non-alcoholic fatty liver disease     132013450 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     132013450 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:mnp01002]     132013450 (CASP8) Enzymes [BR:mnp01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      132013450 (CASP8) Peptidases and inhibitors [BR:mnp01002]  Cysteine peptidases   Family C14: caspase family    132013450 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN COG3_C Motif Other DBs NCBI-GeneID:  132013450 NCBI-ProteinID:  XP_059249180 LinkDB All DBs Position 3:12889200..12912929 Genome browser AA seq 484 aa AA seqDB search MNFSKCLYNIGEQLDSDELASLKFLSMDYIPQKKQEPIKDPLMLFQRLQEKRLLEENNLS FLKELLFRINRLDLLVTYLDTSKQEMEQELQIPGRAQISAYRVMLFQISEDVSKLELKSF KFFLSQEIPRCRVNDDSNLFDIFIEMEKRVILGERNLDTLKRICDLINRSLLKKITDYEE LSQERTMIPQRSLDEISNDMSQLLVGEKSLRIPPMSDSPREQNCGSETSDKVYQMESKPR GYCLIFNNYDFSIARKEVPKLHSIKDRNGTDLDADALHQTFSELHFEIVPFRDSTAKEIC DVLKSYQSMDHTTRDCFICCILSHGDKGIIYGCDGQGVPICELTSYFTGSKCPSLAGKPK IFFIQACQGDNYQKGIAVETDSEQNEACYESDSCQKRYIPDDADFLLGMATVNDCVSYRN PMEGTWYIQTLCQSLRERCPRGEDILSILTEVNFEVSSKDDRRNMGKQMPQPTFTLRKKL IFPL NT seq 1455 nt NT seq  +upstreamnt  +downstreamnt atgaatttcagtaaatgcctctataatattggagaacagctggacagtgatgagctggct tccctcaaattcctgagcatggactacatcccccagaagaagcaggagcccatcaaggat cccctgatgttattccagagactccaggaaaagagactgttggaggaaaacaacctgtcc ttcttgaaggagcttcttttccgaatcaacagactggacctgctggtcacctacctggac accagcaagcaggagatggagcaagagcttcagatcccgggcagagcccagatctctgct tacagggtcatgctttttcagatttcagaagatgtaagcaaactggaattgaagtccttt aagttttttttgagccaggagatccctagatgtagagtgaacgatgattcgaacttgttt gatattttcatagagatggagaagagggtcatcctcggggaaagaaatttggacaccctg aaaagaatctgtgacctaataaacaggagcctgctgaagaaaatcacggattatgaagaa ttaagccaagagcgaacaatgatcccgcaaagaagtctagatgaaatttcaaatgatatg tctcagttgcttgtaggagagaaatcgctgaggataccgccaatgtcagactctccaagg gaacagaactgtggatcagagacatcggacaaagtttaccaaatggaaagcaaacctcga ggatattgtttgatctttaacaattatgactttagcatagcacggaaggaagtgcccaaa cttcacagcattaaggataggaatggaacagacttggatgcagatgctttgcatcagacc tttagtgagcttcattttgagatcgtgcctttcagagactctacggctaaggaaatctgt gacgttctcaaatcctaccaaagcatggaccacactaccagggactgcttcatctgctgc atcctctcccatggagacaagggcatcatctacggctgtgatggacagggagtccccatc tgtgagctcacctcttacttcactggttctaagtgcccttcccttgcagggaagcccaag atcttttttattcaggcttgtcaaggggataactaccagaaggggatcgctgttgagacc gactctgaacagaatgaagcgtgttatgaatcagactcctgtcagaagagatatatccca gacgatgctgactttctgctggggatggccactgtgaatgattgtgtttcctaccgaaac cccatggagggaacgtggtatatccagacactttgccagagcctgagagaaagatgtcct aggggagaagatattctcagcatccttactgaagtgaattttgaagtgagcagtaaggat gacaggagaaacatgggcaaacagatgccacagccgaccttcacgctgcggaaaaagctc atttttcccttgtga

DBGET integrated database retrieval system