Mustela nigripes (black-footed ferret): 132014328
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Entry
132014328 CDS
T09425
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp01522
Endocrine resistance
mnp04012
ErbB signaling pathway
mnp04062
Chemokine signaling pathway
mnp04148
Efferocytosis
mnp04151
PI3K-Akt signaling pathway
mnp04360
Axon guidance
mnp04370
VEGF signaling pathway
mnp04510
Focal adhesion
mnp04670
Leukocyte transendothelial migration
mnp04810
Regulation of actin cytoskeleton
mnp04935
Growth hormone synthesis, secretion and action
mnp05100
Bacterial invasion of epithelial cells
mnp05135
Yersinia infection
mnp05146
Amoebiasis
mnp05163
Human cytomegalovirus infection
mnp05165
Human papillomavirus infection
mnp05170
Human immunodeficiency virus 1 infection
mnp05200
Pathways in cancer
mnp05202
Transcriptional misregulation in cancer
mnp05205
Proteoglycans in cancer
mnp05208
Chemical carcinogenesis - reactive oxygen species
mnp05222
Small cell lung cancer
mnp05417
Lipid and atherosclerosis
mnp05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
132014328 (PTK2)
04370 VEGF signaling pathway
132014328 (PTK2)
04151 PI3K-Akt signaling pathway
132014328 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
132014328 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
132014328 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
132014328 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
132014328 (PTK2)
04062 Chemokine signaling pathway
132014328 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
132014328 (PTK2)
09158 Development and regeneration
04360 Axon guidance
132014328 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132014328 (PTK2)
05202 Transcriptional misregulation in cancer
132014328 (PTK2)
05205 Proteoglycans in cancer
132014328 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
132014328 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
132014328 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
132014328 (PTK2)
05163 Human cytomegalovirus infection
132014328 (PTK2)
05165 Human papillomavirus infection
132014328 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
132014328 (PTK2)
05100 Bacterial invasion of epithelial cells
132014328 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
132014328 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
132014328 (PTK2)
05418 Fluid shear stress and atherosclerosis
132014328 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
132014328 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mnp01001
]
132014328 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
mnp01009
]
132014328 (PTK2)
Enzymes [BR:
mnp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
132014328 (PTK2)
Protein kinases [BR:
mnp01001
]
Non-receptor tyrosine kinases
FAK family
132014328 (PTK2)
Protein phosphatases and associated proteins [BR:
mnp01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
132014328 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
GIT1_C
ABC1
Motif
Other DBs
NCBI-GeneID:
132014328
NCBI-ProteinID:
XP_059251200
LinkDB
All DBs
Position
3:complement(194721726..194968907)
Genome browser
AA seq
1136 aa
AA seq
DB search
MWLELAGRVALRPAGAVCMEKSGCSPFPVCWAKEYDRYIASSKIMAAAYLDPNLNHTPNS
CTKTHLGAGAERSPGAMERVLKVFHYFENSSEPATWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMSEVADRVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKP
ANSEKQGVRTHAVSVSGVSPRQHKVKKARRFLPLVFCSHEPSTDEISGDETDDYAEIIDE
EDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKTC
KNSTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKY
SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTY
YKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE
NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQQEERMRMESR
RQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGVTAM
AGSIYPGQASLLDQTDSWNHRAQEISMWQPSVEDSAALDLRGIGHVLPTHLMEERLIRQQ
QEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPTGNQHIYQPVGKPDPAAPPKKP
PRPGAPGHLGSLASLSSPGDSYNEGVKLQPQEISPPPTANLDRSNDRVYENVTGLVKAVI
EMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETLPVLPASTHREIEMAQKLLNSDLGE
LINKMKLAQQCVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLRMLGPTRPH
NT seq
3411 nt
NT seq
+upstream
nt +downstream
nt
atgtggctggaactggcgggccgagtggccctgagaccagcaggtgccgtctgtatggag
aagagcggctgtagtccattcccagtttgttgggctaaagagtatgacagatacatagca
tctagcaaaataatggcagctgcttaccttgacccaaacttgaatcatacaccgaattcg
tgtaccaagactcacctgggcgccggcgcggagcggtcccccggggcaatggagcgggtg
ttgaaagtctttcattactttgaaaacagcagcgaaccagctacttgggccagtattatc
aggcacggggatgcgactgacgtccggggcatcattcagaagatagtggacagtcacaaa
gtaaagcacgtggcctgctatggatttcgcctcagtcacctgcggtcagaggaggttcac
tggctccatttggatatgggtgtctccaatgtgagggagaagtatgaacttgcacaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagacaagccaactctgaatttcttctaccaacaggtcaagagcgactacatg
tcagaggtggctgaccgtgtggaccaggacattgctctgaagctgggctgtctggaaatc
cggcgctcgtactgggagatgcgaggcaacgcgctggagaagaagtccaactacgaagtg
ttggaaaaagatgttggtttgaagcgattttttcctaggagtttactggattctgtcaag
gccaaaacgctacggaagctgatccaacagacgtttagacagtttgccaaccttaacaga
gaagaaagtattctgaaattctttgagatcctctccccggtgtatagattcgataaagaa
tgcttcaagtgtgctctgggttcaagctggattatctcagtggaactggcaattggccct
gaagaaggcatcagttacctcacagacaagggctgcaatcccacacatctggccgacttc
aatcaagtgcagaccattcagtactcgaacagtgaagacaaggacaggaaagggatgctg
cagctgaaaatcgccggcgcgcccgagcctctgacagtgacagcgccgtccctaaccatc
gccgagaatatggcggacttgatagatgggtactgccggctggtgaacggggccacacag
tcttttatcatcagaccccagaaagaaggcgaacgggctttgccatcgataccaaagccg
gccaacagcgagaagcaaggcgtgcggacacacgcggtctctgtgtcaggagtcagtccc
cgccagcataaagttaagaaagctaggcgctttctccctttggtcttctgttcccatgag
ccttctaccgatgaaattagtggggacgaaacggatgattatgctgagatcatagacgaa
gaagacacctacaccatgccctcgaaaagctatggaatagatgaagccagggattatgag
attcagagagaaagaatcgagcttggacggtgcatcggggaaggccagtttggagacgtc
catcaaggcgtctacatgagcccagagaacccagcgctggcggttgcaattaaaacatgt
aaaaactctacttcggacagcgtgagagagaaattccttcaagaagccttgacgatgcgg
cagttcgaccaccctcacattgtgaagctgatcggcgtcatcacggagaaccccgtctgg
ataatcatggagctgtgcacgcttggagagctgaggtcatttctgcaagtaaggaagtac
agtttggatctggcgtctctgatcctctatgcctatcaacttagtacagctctcgcgtat
ctggagagcaaaagatttgtgcacagggacattgctgctcggaacgttctggtgtcctca
aatgattgtgtaaaactaggagactttggattatcccgatacatggaagacagtacttac
tacaaagcttccaaaggaaaattgccaattaagtggatggctccagagtccatcaatttt
cgacgttttacctcagctagtgatgtgtggatgtttggtgtgtgtatgtgggagatactg
atgcacggcgtgaagccctttcaaggagtgaagaacaacgacgtgatcggtcggattgag
aatggggagaggctgccgatgccgccaaactgccctccgaccctctacagccttatgacg
aaatgctgggcctatgaccccagcaggcggccgcggttcactgagctcaaagctcagctc
agcacaatcctggaggaggagaaggtccagcaggaagagcgaatgaggatggagtccaga
agacaggtcaccgtgtcctgggactccggagggtccgacgaagcgccgcccaagcccagc
agacccggttaccccagtccaaggtccagcgaaggattttaccccagtcctcagcacatg
gtacagaccaatcattatcaggtctctggctatcctggatcccatggggtcacggccatg
gctggcagcatctacccgggccaggcatctctcttggaccagacggactcctggaatcac
agagcgcaggagatatcaatgtggcagcccagcgtggaggactcggcggcgctggacctg
cgcgggatcgggcacgtgttgccgacccacctgatggaggagcggctgatccggcagcag
caggagatggaggaagatcagcgctggctggaaaaggaggagaggtttctgaaacccgac
gtccggctctctcgaggcagtattgacagggaggacggaagcctccagggcccgactgga
aaccagcacatctatcagcctgtggggaaaccagatcctgcagctccgccaaagaaaccg
ccacggcctggggcccccggtcacctgggcagccttgccagcctcagcagccccggggac
agttacaacgagggtgtcaagcttcagccccaggaaatcagccccccgcccactgccaat
ctggaccggtccaacgacagggtgtacgagaatgtgacgggcctggtgaaggctgtcatc
gaaatgtccagcaagatccagccagccccaccagaggagtacgttcccatggtgaaggaa
gtcggcctggccctgcggacattactggccaccgtggacgagacccttccggtcctgcca
gccagcactcaccgagagatcgagatggcccagaagctgttgaactccgacctgggcgag
ctcatcaacaagatgaaactggctcagcagtgcgtcatgaccagcctccaacaggagtat
aagaagcagatgctgaccgctgcgcacgccctggccgtggacgccaaaaacttgctggac
gtcattgaccaagcgagactgcggatgctcgggcccacgaggccgcactga
DBGET
integrated database retrieval system
