KEGG   Mustela nigripes (black-footed ferret): 132016218
Entry
132016218         CDS       T09425                                 
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
mnp  Mustela nigripes (black-footed ferret)
Pathway
mnp00562  Inositol phosphate metabolism
mnp01100  Metabolic pathways
mnp01521  EGFR tyrosine kinase inhibitor resistance
mnp04068  FoxO signaling pathway
mnp04070  Phosphatidylinositol signaling system
mnp04071  Sphingolipid signaling pathway
mnp04115  p53 signaling pathway
mnp04140  Autophagy - animal
mnp04150  mTOR signaling pathway
mnp04151  PI3K-Akt signaling pathway
mnp04218  Cellular senescence
mnp04510  Focal adhesion
mnp04931  Insulin resistance
mnp05165  Human papillomavirus infection
mnp05166  Human T-cell leukemia virus 1 infection
mnp05200  Pathways in cancer
mnp05206  MicroRNAs in cancer
mnp05208  Chemical carcinogenesis - reactive oxygen species
mnp05213  Endometrial cancer
mnp05214  Glioma
mnp05215  Prostate cancer
mnp05218  Melanoma
mnp05222  Small cell lung cancer
mnp05224  Breast cancer
mnp05225  Hepatocellular carcinoma
mnp05230  Central carbon metabolism in cancer
mnp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mnp05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mnp00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    132016218 (PTEN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    132016218 (PTEN)
   04070 Phosphatidylinositol signaling system
    132016218 (PTEN)
   04071 Sphingolipid signaling pathway
    132016218 (PTEN)
   04151 PI3K-Akt signaling pathway
    132016218 (PTEN)
   04150 mTOR signaling pathway
    132016218 (PTEN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    132016218 (PTEN)
  09143 Cell growth and death
   04115 p53 signaling pathway
    132016218 (PTEN)
   04218 Cellular senescence
    132016218 (PTEN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    132016218 (PTEN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    132016218 (PTEN)
   05206 MicroRNAs in cancer
    132016218 (PTEN)
   05208 Chemical carcinogenesis - reactive oxygen species
    132016218 (PTEN)
   05230 Central carbon metabolism in cancer
    132016218 (PTEN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    132016218 (PTEN)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    132016218 (PTEN)
   05214 Glioma
    132016218 (PTEN)
   05218 Melanoma
    132016218 (PTEN)
   05215 Prostate cancer
    132016218 (PTEN)
   05213 Endometrial cancer
    132016218 (PTEN)
   05224 Breast cancer
    132016218 (PTEN)
   05222 Small cell lung cancer
    132016218 (PTEN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    132016218 (PTEN)
   05165 Human papillomavirus infection
    132016218 (PTEN)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    132016218 (PTEN)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    132016218 (PTEN)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    132016218 (PTEN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mnp01009]
    132016218 (PTEN)
Enzymes [BR:mnp01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     132016218 (PTEN)
    3.1.3.48  protein-tyrosine-phosphatase
     132016218 (PTEN)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     132016218 (PTEN)
Protein phosphatases and associated proteins [BR:mnp01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    132016218 (PTEN)
SSDB
Other DBs
NCBI-GeneID: 132016218
NCBI-ProteinID: XP_059253390
LinkDB
Position
4:complement(118031203..118032354)
AA seq 378 aa
AAAGAAPSGSRPAGGGGSGGVSRLVLVLSSNRAASRSASRARDGGSRGPGREPAEARRRQ
RQRQRHLPLLERGGEAAAPAAAAAAPGRGPESPVTISRAGAAGELVSPLLLPPTRRRRRR
HVQGPGPAVNLPSAAAAPPPARAPEAAGGGSDRPEDSPSPSRPAAAAARPLAAEEKQAPS
LQPSSSRRSSHYPAAVQSQAAAERGASATAKSRAISILQKKPRHQQLLPSLSSFFFSHRL
PDMTAIIKEIVSRNKRRYQEDGFDLDLTCIHFCRCPSLPFCHSRLERGSRRRRKISMVWV
TVAANPARISRSCLFGVSLECIQPRVCSATWNSGPLASVKAPIAFSGLCAGSLPKGYCPL
TQNAVHCWWISELGNPVC
NT seq 1137 nt   +upstreamnt  +downstreamnt
gcagccgcgggggcagcgccctcggggagccggccggccggcggcggcggcagcggcggc
gtctctcgcctcgtcctcgttctctcttctaaccgtgcagcctctcgctcggcttctcgt
gcaagggacggtggaagccgcgggcccgggcgggagccggctgaggcgcggcggcggcag
cggcagcggcagcggcacctcccgctcctggagcgggggggagaagcggcggcgccggcc
gcggcggctgcagctccggggagggggccggagtcgcctgtcaccatttccagggctggg
gccgccggagagttggtctctcccctcttactgcctccaacacggcggcggcggcggcgg
cacgtccagggacccgggccggctgtaaacctcccctccgccgccgccgcaccccccccg
gcccgggctccggaggccgccggcggaggcagcgaccgtcccgaggattcgccgtctcct
tctcgtcccgcggccgccgcggccaggcctctggctgctgaggagaagcaggccccgtcg
ctgcaaccatccagcagccgccgcagcagccattacccggctgcggtccagagccaggcg
gcggcagagcgaggggcatccgctaccgccaagtccagagccatttccatcctgcagaag
aagccccgccaccagcagcttctgccatctctctcctcctttttcttcagccacaggctc
ccagacatgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagag
gatggattcgacttagacttgacctgtatccatttctgccgctgcccctctctgcctttc
tgtcactctcgcttagaacgtgggagcagacggaggcgaaaaatttccatggtttgggtg
accgtagcagctaaccctgctcgaatttctagatcgtgtctctttggtgtctctcttgaa
tgcatccagcctagggtgtgttcggctacatggaactctggcccgcttgcgagtgtcaag
gcaccgattgctttctcgggtctgtgtgcggggtctcttccgaagggctattgtccgcta
acacagaacgcggtacactgttggtggattagtgagctcggtaatccggtctgctaa

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