Mustela nigripes (black-footed ferret): 132021375
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Entry
132021375 CDS
T09425
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04137
Mitophagy - animal
mnp04140
Autophagy - animal
mnp04141
Protein processing in endoplasmic reticulum
mnp04210
Apoptosis
mnp04932
Non-alcoholic fatty liver disease
mnp05010
Alzheimer disease
mnp05012
Parkinson disease
mnp05014
Amyotrophic lateral sclerosis
mnp05020
Prion disease
mnp05022
Pathways of neurodegeneration - multiple diseases
mnp05160
Hepatitis C
mnp05162
Measles
mnp05168
Herpes simplex virus 1 infection
mnp05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
132021375 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
132021375 (EIF2AK3)
04137 Mitophagy - animal
132021375 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
132021375 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
132021375 (EIF2AK3)
05162 Measles
132021375 (EIF2AK3)
05168 Herpes simplex virus 1 infection
132021375 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
132021375 (EIF2AK3)
05012 Parkinson disease
132021375 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
132021375 (EIF2AK3)
05020 Prion disease
132021375 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
132021375 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
132021375 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
132021375 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mnp01001
]
132021375 (EIF2AK3)
Enzymes [BR:
mnp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
132021375 (EIF2AK3)
Protein kinases [BR:
mnp01001
]
Serine/threonine kinases: Other
PEK family [OT]
132021375 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
ABC1
Kdo
DUF7670
Motif
Other DBs
NCBI-GeneID:
132021375
NCBI-ProteinID:
XP_059261625
LinkDB
All DBs
Position
7:38778756..38844749
Genome browser
AA seq
1109 aa
AA seq
DB search
MERATRPGTLARALLLLLLLLLLGLAAGAVAAGRASDLPATKAETAFGLGAAAAPTSAAR
VPAAGAVTTAEVTVEDAEAVPAAAVEQEPRDPEPDDEAELRPRGRSLVIISTLDGRIAAL
DPENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTV
ESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDNDDMEQEDILLLQ
RSQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTLKPSGNKEGSKIISDVE
DQEAAMMDTVIKVSVADWKVMAFNKKGGHLEWEYQFCTPIASAWLVKDGKVIPISLFDDT
SYASNNEVLEDEEDIVEAARGATENSVYLGMFRGQLYLQSSVRISEKFPTSPKALESVNN
EYAIMPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNG
YYLPYYKRERSKRSTQITVRFLDNPNYSKNIRKKDPVLLLHWWKEIVGTILFCIIATTFI
VRRLFHPHPHRQRKESETQCQTESKYDSVNGEAKDSSWNDIKNSGYVSRYLTDFEPVQCL
GRGGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLDHPGIVRYFNAWL
EAPPEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRMDPFSTKEHIEIIAPSSQRR
SFSVGISCGQTSSSESQFSPLEFLGTDHGDSSESADAACNLRDSCLTDCDTGDGTLDGHD
EGHSFELCPSGTSPYERSGERTSSSIVFEDSGCDNASSKEELRTKRLHLSNHCTNKLTAL
QPSSSQSSSEPAFSVSPPRPTTLSLDLTKNTAEKLQPSSPKVYLYIQMQLCRKENLKDWL
NSRCTLEERERSVCLLIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTVDNVVKVGDFGLVT
EMDQDEEEQMVLTPMPAYARHTGQVGTKLYMSPEQIHGNNYSHKVDIFSLGLILFELLYP
FGTQMERVRILTDVRNLKFPPLFTQKYPREYVMVQDMLSPSPMERPEATTIIENAVFEDL
ELPGKTVLRQRSRSMSSSGTKHSRQSSSS
NT seq
3330 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccacccgcccggggacgctcgcgcgggcgctgttgctgctgctgctgctg
ctgctgctgggactggctgcgggcgccgtggccgcggggcgcgcctccgacctacccgcg
acgaaggcagagacggcgttcggcctgggggcagcggccgctcccacttctgcagcgcgg
gtgccggcggccggggccgtgactacggccgaagtgacggtggaggacgcggaagctgtg
ccggcggccgcggtggagcaggagccgcgggaccccgaacccgacgacgaggccgagcta
cgaccgcgcggcagatcattagtgattatcagcactttagatgggcgaattgctgccttg
gatcctgagaatcatggtaaaaaacagtgggatttggacgtgggatccggttccttggtt
tcatccagcctcagcaaaccagaggtatttgggaataagatgatcattccttctctggat
ggagacctcttccaatgggaccgggaccgtgagagcatggaaacagttccttttacagtt
gaatcacttcttgaatcttcttataaatttggagatgatgttgttttggttggaggaaag
tctctcacgacatatggactcagcgcatacagtggaaaggtgaggtacatctgttcagct
ttgggttgtcgccaatgggataatgatgatatggaacaagaagacatccttcttctgcaa
cgctcccagaaaactgtcagagctgtcggacctcgcagtggcaacgagaagtggaatttc
agtgttggccactttgaacttcggtatattccagacatggaaactagagccggatttatt
gaaagtaccctaaagcccagtgggaacaaagaagggtctaaaattatttcagatgtggaa
gaccaggaagccgccatgatggacacagtgataaaggtctcagttgctgactggaaggtt
atggcatttaacaagaagggaggacatctggaatgggaataccagttttgtactcccatt
gcatctgcttggttggttaaggatggaaaagtcattcccatcagtctttttgatgataca
agttatgcatctaacaatgaagttttagaagatgaagaagacattgtagaagctgctcga
ggagccacagaaaacagcgtttacctgggaatgttccgaggtcagttgtatctgcagtca
tcagtcagaatttcagaaaagtttcctacaagtcccaaggccttggaatctgtcaataat
gagtatgcaattatgcctttgccaacaatcaagtggaaacccttaattcattctccttcc
agaactcctgtcttggtagggtctgatgaatttgacaaatgtcttagtaacgataagttt
tctcatgaagagtacagtaatggcgcactttcaatcttgcagtacccatatgataatggt
tattatctaccatattacaagagggagaggagcaaacggagcacacagatcacagtccga
ttcctcgataacccaaattacagcaagaacattcgcaaaaaggatcctgtcctcctctta
cactggtggaaagaaatagttggaactattctgttttgtatcatagcaacaacttttatt
gtgcgtagacttttccatcctcatcctcacagacaaaggaaggaatctgaaactcagtgc
caaactgaaagtaaatatgattctgtcaatggagaagctaaggacagtagctggaatgac
ataaaaaattctggatatgtatcacgctatctaacagattttgaaccagttcagtgcttg
ggtcgtggtggatttggagtcgtctttgaagccagaaacaaagtagatgactgcaattat
gctatcaagagaatccgcctccccaacagggagttggctcgggaaaaggtaatgcgggaa
gttaaagccttagccaagcttgaccatccagggattgttaggtatttcaatgcttggttg
gaagccccaccagaaaagtggcaagaaaaaatggatgaaatttggctgaaagatgaaagc
acagactggccactcagctctcctagtccaatggatgccccatcagttaagatacgccga
atggatcctttctctacaaaggaacatattgaaatcatagctccttcttcacaaaggagg
tctttttcagtagggatttcctgtggccagacgagttcttccgagagccagttctctccg
ctggaatttttaggaacggaccacggggacagcagtgagtccgcggatgccgcgtgcaac
ctccgggacagctgccttacggactgcgacacgggagatggtactctggatggccatgac
gagggtcactccttcgaactgtgtccttctggaacttctccttatgaaaggtcaggggaa
agaacatcctcttctatagtatttgaagattctggctgtgataacgcgtccagtaaagaa
gaactcagaacgaagcgactgcatctgagcaaccactgcactaataaactaactgccctc
cagccttccagtagccagtcttcttctgaacctgcgttctctgtttctcctcccagaccc
accactttaagtttagatctcactaaaaacaccgcagaaaaactccagcccagttccccg
aaggtgtatctttacattcagatgcagctctgcagaaaggaaaacctcaaagactggctg
aacagccggtgcaccctagaggagagggaaagaagcgtgtgtctgctcatcttcctgcag
atcgcggaggcggtggagtttctgcacagtaaagggctcatgcacagggacctcaagcct
tccaatatattctttacagtggacaatgtggtcaaggttggagactttggattagtgacc
gaaatggaccaggacgaggaagagcagatggttctgaccccgatgccagcatatgccaga
cacacaggacaagtggggaccaagctgtatatgagcccagagcagattcatggaaacaac
tactctcataaagtggacatcttttctttaggcctcattctgtttgaattgctgtaccca
ttcggcactcagatggagagagtcaggatcttaactgatgtaagaaatctcaaatttcca
ccactgtttactcagaaatatcctcgtgagtatgtgatggttcaagacatgctctctcca
tcccccatggaacggccagaagctaccaccatcattgaaaatgctgtatttgaagacttg
gagcttccaggaaaaacagtactcagacagaggtctcgctccatgagttcatcaggaaca
aaacattcaagacagtccagcagctcctag
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integrated database retrieval system
