Mustela nigripes (black-footed ferret): 132021852
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Entry
132021852 CDS
T09425
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04120
Ubiquitin mediated proteolysis
mnp04144
Endocytosis
mnp04330
Notch signaling pathway
mnp04668
TNF signaling pathway
mnp04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
132021852 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
132021852 (ITCH)
04668 TNF signaling pathway
132021852 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
132021852 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
132021852 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mnp04131
]
132021852 (ITCH)
04121 Ubiquitin system [BR:
mnp04121
]
132021852 (ITCH)
Enzymes [BR:
mnp01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
132021852 (ITCH)
Membrane trafficking [BR:
mnp04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
132021852 (ITCH)
Ubiquitin system [BR:
mnp04121
]
Ubiquitin ligases (E3)
HECT type E3
132021852 (ITCH)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
CEP164_N
Motif
Other DBs
NCBI-GeneID:
132021852
NCBI-ProteinID:
XP_059262811
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All DBs
Position
7:116639316..116768909
Genome browser
AA seq
880 aa
AA seq
DB search
MYCWILLASILICRPIGGMSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPY
VEVTVDGQSKKTEKCNNTNSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDI
FETLKSNNMKLEEVVVTLQLVGDKEPTETIGDLSVCLDGLQLDSEVVTNGETTCSESASQ
SDDGSRPKDETRTNTNGSDEPEDAGAGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPT
PRRPASVNGSPSATSESDGSSTGSLPTTNINSNTSEGATSGLIIPLTISGGSGPRPLNPV
PQAPLPPGWEQRVDQHGRVYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRT
TTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPG
WEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRT
TTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQ
QIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQ
INPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPE
FYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAE
WRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYT
RTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKEN
WLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2643 nt
NT seq
+upstream
nt +downstream
nt
atgtactgttggatcctattggctagtattttgatttgccgtcctattggtggtatgtct
ggcagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaacttcagatc
actgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagtccttat
gtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacgaacagt
cccaaatggaagcaaccccttacagttatcgtcacccctgtgagtaaattacattttcgt
gtatggagtcaccagacactgaaatctgatgttttgttgggaactgctgcattagatatc
tttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgactttacagctt
gtaggtgacaaagagccgacagagacaataggagacttgtcagtttgtcttgatgggctg
cagttagattctgaagttgttaccaatggtgaaactacatgttcagaaagtgcttcacag
agtgatgatggctccagacccaaggatgaaacaagaacaaacacaaatggatcagatgag
cctgaggatgcaggggctggtgaaaataggaaggtcaatgggaataattctccatcactc
tcaaatggtggttttaaaccttctaggcctccaagaccttcacgaccacctccacctacc
ccacgtagaccagcatctgtcaatggttccccatctgccacttctgaaagtgatggatcc
agtacaggctctctgccaacaacaaatataaattcaaatacatctgaaggagcaacatct
ggattaataattcctctgactatatctggaggctcaggccctcggccattaaatcctgta
cctcaggctcccctaccacctggttgggagcagagagtggaccagcatgggcgagtttac
tatgtagatcatattgaaaaaagaacaacatgggatagaccagaacctctacctcctggc
tgggaacgtcgggttgacaacatgggacgaatttactatgttgaccatttcacaagaaca
acaacgtggcagaggccaacattggaatccgtccggaactatgaacagtggcagctccaa
cgtagtcagctgcaaggagcaatgcagcagtttaaccagagatttatttatgggaatcaa
gatttgtttactacatcacaaaataaagaatttgatccccttggtcccctgccacctgga
tgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacactcgtatc
acacagtgggaagatcccagaagtcaaggtcaattaaatgaaaagcccttgcctgaaggc
tgggaaatgagattcacagtcgatggaattccgtattttgtggaccacaatagaagaaca
accacctatattgatccccgcactggaaaatctgccctagacaatggaccacagatagcc
tatgtacgggatttcaaggcaaaagttcagtatttccggttctggtgtcagcaactggcc
atgccacagcacataaagattacagtgacaagaaagaccttgtttgaagattcctttcag
cagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgatttttccagga
gaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtcacacgaa
gtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgcttgcag
attaatcctgcttcttacatcaatccagatcacctgaaatactttcgttttattggcagg
tttattgccatggctctcttccatgggaaattcatagacacaggtttttctttgccattc
tataaacgtatattgaacaaaccagttggactcaaggatttagaatctattgatccagaa
ttttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttggaaatg
tacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaacctaat
ggtggcaatattcttgtgacagaagaaaataaagaggaatatatcagaatggtagctgaa
tggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggctttaatgaa
attcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtccttttatgt
ggaatgcaagaaattgacttgaatgactggcaaagacatgccatctaccgccattacact
aggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataatgagaag
agaatgagacttctgcagtttgttactggaacctgccgattgccagttggaggatttgct
gacctcatggggagtaatggaccacaaaaattctgcattgaaaaagttgggaaagaaaat
tggttacccagaagtcatacgtgttttaatcgcctggacctgccaccctacaagagctat
gagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttggacaagag
taa
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