Mustela nigripes (black-footed ferret): 132023261
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Entry
132023261 CDS
T09425
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00061
Fatty acid biosynthesis
mnp00620
Pyruvate metabolism
mnp00640
Propanoate metabolism
mnp01100
Metabolic pathways
mnp04152
AMPK signaling pathway
mnp04910
Insulin signaling pathway
mnp04920
Adipocytokine signaling pathway
mnp04922
Glucagon signaling pathway
mnp04931
Insulin resistance
mnp04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
132023261 (ACACB)
00640 Propanoate metabolism
132023261 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
132023261 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
132023261 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
132023261 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
132023261 (ACACB)
04922 Glucagon signaling pathway
132023261 (ACACB)
04920 Adipocytokine signaling pathway
132023261 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
132023261 (ACACB)
04931 Insulin resistance
132023261 (ACACB)
Enzymes [BR:
mnp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
132023261 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
132023261 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
132023261 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
Motif
Other DBs
NCBI-GeneID:
132023261
NCBI-ProteinID:
XP_059264617
LinkDB
All DBs
Position
8:17414669..17540488
Genome browser
AA seq
2456 aa
AA seq
DB search
MILLLFLSCLIFSCLTFSWLKIWGKMTDSMPVTKSKSEGSCIPSQEPFPASYSSGEPLQK
NSDCSPLPETPNQAKPASHKGPKDACRPRTSRPLPHQNSPGNPHTSDNTPAALQANGMGT
EGLKTLDTSGLPSSAKPQGQRARPFSKEDEKQEHIKRQLMTNFILGSFDDNSSDEDPGAG
LFRESSRKGSRASLGTMSLEAASTVGESENPIPAMRPSMSGLHLVKRGRELKKLDLHRDF
TVASPAEFVTRFGGNRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPE
DLKANAEYIKMADQYVPVPGGPNNNNYANVELVVDIAKRIPVQAVWAGWGHASESPKLPE
LLCKHEIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLMVEWAEGDLQQGKRI
TVPEDVYNQGCVKDIDEGLEVAEKIGFPLMIKASEGGGGKGIRKAESAEDFPVLFRQVQT
EIPGSPIFLMKLAEHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAIPA
VFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPA
AQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFDTPANPPLARGHVIAARITSENPDEGF
KPSSGTVQELNFRSNRNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALK
ELSIRGDFRTTVEYLINLLETERYQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNV
ADSMFRTCMTDFLHSLERGQVLPAASLLNIVDVELIYGGVKYILKVARQSLTMFILIMND
CHIEIDAHRLSDGGLLLSYNGNSYTTYMKEEFDSYRITIGNKTCVFEKENDPTVLRAPSA
GKLIQYTVEDGGHVEAGSSYADMEVMKMIMTLNVQESGRIKYIERPGATLEAGCVVARLD
LDDPSKVHPAKPFTGKLPSQQTLPIMGEKLHQVFHNVLENLTNVMSGYCLPEPIFSTKLK
EWVQKLMMTLRHPSLPLLELQEIMTSVSGRIPTPVEKSVRRVMAQYASNITSVLCQFPSQ
QIATILDCHAATLQRKAEREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRRYLRVEH
HFQQAHYDKCVINLREQLKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEEL
TSILIELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN
LKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVE
FQFMLPSSHPNRMAAPISITNPDLLRHSTELFMDSGFSPPCQRMGAMVAFRRFEDFVRNF
DEVIFCFANVPQEAPLLSKACTSLYCEEDSKNLREEPIHILNVAIQHADHLEDEELVPIF
RTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAYQLEL
SRMRSFDLTAVPCANHKMHLYLGAAKVKEGAEVTDYRFFIRAIIRHSDLITKEASFEYLQ
NEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRL
WKLRVLQAEVKINIRQTTAGNAVPIRLFITNESGYYLDISLYKEVTDPRSGNIMFHSFGD
KQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGTPDKYPKDI
LTYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMRFKTPEYPEGRDVIVISNDITFRIGSF
GMGEDLLYLRASEMARAEGIPRIYLAANSGAGIGLAEEIKHIFQVAWVDPGDPNKGFKYL
YLTPQDYTTVSSLNSVHCKHIEEDGESRYVITDIIGKDSGVGVENLRGSGMIAGESSLAY
EEIVTISLVTCRAVGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGG
VQIMHYNGVSHTTVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREVGYYPTKAP
YDPRWLLAGKPHPTLKGSWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETR
TVEVVIPADPANLDSEAKIIQQVGQVWLPDSAYKTAQAIKDFNREKLPLIIFANWRGFSG
GMKDMYDQMLKFGAYIVDSLRQYKQPILSYIPPNAELRGGSWVVMDSSINPLCIELYADK
ESRANILEPEGTVEIKYRKKDLIKTMRRIDPTYKKLVEQLGTPGLSDKDRKDLEGQLKAR
EQLLLPIYHQVAVQFASLHDKPICMLEKGALADILEWKTSRTFLYWRLRRLLLEDQIRQE
ILQASPELSHVHIQSMLRRWFVETEGAVKAYMWDNNQMVVRWLEQHWQAGDSLHSTIREN
IKCLKRDSVLKAIRGLVQDNPEVAADCIVYMSQHVSPAERAQVIHLLSTMDSPAST
NT seq
7371 nt
NT seq
+upstream
nt +downstream
nt
atgatattgcttctttttctatcttgtttgattttctcctgcttgaccttttcctggtta
aaaatctgggggaaaatgacagactctatgccagtcaccaagagtaaatcagaagggagc
tgtatcccaagccaggagccctttccagcatcatacagctcaggggagccactgcagaaa
aacagtgactgcagccctctgccagagactcctaaccaggccaagccagcctcccacaaa
ggtcctaaagatgcctgtcggccgagaacttccaggccactcccacaccagaattcccca
ggaaacccccatacttcggataacacccctgcagcactccaagccaatgggatgggaacc
gaaggcctgaagaccctggataccagtggcctgccatcttcagccaagccccaaggccag
cgagccagacccttctccaaagaagacgagaagcaagagcacatcaagaggcagctgatg
accaacttcatcctgggctcctttgatgacaactcctctgatgaggaccctggcgctggc
ttgttccgagagtcttcccggaagggcagccgggccagcctggggaccatgtccctggag
gccgcttcgactgtaggcgaatccgagaaccccattcccgctatgagacctagcatgtct
ggactccacctggtgaagaggggccgagaactgaagaagctggacctgcacagagacttt
actgtggcctccccggctgagtttgtcacacgctttggggggaaccgggtcattgagaag
gtgctcatcgccaacaatggcatcgccgccgtgaagtgcatgcgctccatccgcaggtgg
gcctatgagatgtttcggaacgagcgggccatccggtttgtagtcatggtgaccccagag
gacctgaaggccaatgcagagtatatcaagatggcagatcagtatgtccctgtcccggga
gggcccaacaacaacaattatgccaatgtggagttggttgtggacattgccaagaggatc
cccgtgcaggcggtgtgggctggctggggccatgcttctgaaagccccaaactgccggag
ctcctgtgcaagcacgagattgctttcttaggccctccgagtgaggccatgtgggccttg
ggagataagatcgcctccaccattgtggcccagacactgcagatcccaacactgccctgg
agcggaagcggtctgatggtggaatgggcagaaggtgatctgcagcaggggaaaagaatc
actgtcccagaagatgtttacaaccagggttgtgtgaaagatatagatgagggcttagag
gtggcagaaaaaattggttttcccttgatgatcaaagcatccgaaggcggtggagggaaa
ggaatccggaaggcagagagtgctgaggacttcccagtccttttcagacaagtgcagact
gagatccccggctcccccatcttcctcatgaagctggccgagcatgcccgacatctggag
gtccagatccttgctgaccagtatgggaacgccgtgtccctgtttgggcgtgactgctcc
atccagcggcggcatcagaagatcattgaggaggcgccggccaccattgccataccggct
gtcttcgagttcatggagcagtgtgccgtccgcttggccaagactgtgggctacgtgagc
gcggggacggtagaatatctctacagccaagatggcagtttccacttcttggagctgaat
ccccgcctgcaagtggagcacccctgcacagagatgatcgcggatgtcaacctgccggct
gcccagctgcagattgccatgggggtgccattgcaccggctgaaggatatccggcttctg
tatggagagtcgccatggggcgtgacgcccatttcatttgacactcctgccaaccctccg
ctcgcccgaggccatgtcatcgcggccagaatcaccagtgagaaccctgatgaggggttt
aagccaagctctggaacggttcaggaactgaatttccggagcaacagaaacgtctggggt
tatttcagcgtggcggctgctggcggcttacacgaatttgctgactcccagttcgggcac
tgcttctcctggggagagaaccgggaagaggccatttcgaacatggtggtggctttgaag
gaactgtccatccgaggcgacttcaggaccaccgtggagtatctcattaacctgctggag
actgagcgctaccagaacaacgacatcgacactggctggttggattacctcattgctgag
aaagtgcaggctgagaaaccagatatcatgctcggtgtggtgtgcggggccttgaacgtg
gccgactcgatgttcagaacttgcatgacggatttcttacactcgctggaaaggggccag
gtccttcctgcagcttctctgctgaacattgtggatgtggaattaatttatggaggtgtt
aagtacatcctcaaggtggcccggcaatctctgaccatgttcatcctcatcatgaacgac
tgtcatatcgagatcgatgcccaccggctaagcgatggggggctcctgctgtcctataat
ggtaacagctataccacctacatgaaagaagagtttgacagttaccgtattaccatcggc
aacaagacttgcgtgtttgagaaggagaacgatcccacggtcctgagggccccttcagct
gggaaactaatacagtacacggtggaggacgggggccatgttgaggcagggagcagctat
gccgacatggaggtaatgaagatgatcatgaccctgaatgtgcaggagagtggccggatc
aaatacattgagcgcccaggggccacgctggaagcaggctgtgtggtggccaggctggac
ctcgacgacccttccaaagtgcacccggccaagccattcacaggaaagctcccttcccag
caaactctacccatcatgggagagaaactgcaccaggttttccacaatgtcctggaaaac
ctgaccaacgtcatgagtggctactgtctgccggagcctatttttagcacaaagctgaag
gagtgggtgcagaagctcatgatgaccctccggcacccatcactgccgctcttggaactg
caggaaatcatgaccagcgtgtctggccgcatccccactcccgtggagaagtctgttcgc
agggtgatggctcagtacgccagcaacatcacctcagtgctgtgccagttccctagccag
cagatagccaccatcctagactgccatgcagccaccctgcagcggaaggctgaacgggag
gtattcttcatgaacactcagagcatcgtgcagctggtccagaggtaccgcagtgggacc
cgaggctacatgaaagcagtggtgttggaccttctgcggagatatttacgggtggagcac
catttccaacaagctcactatgacaagtgtgtgatcaacctcagggagcagctgaagcca
gacatgtcccaggtgctggactgcatcttttcccacgcacaggtggccaagaagaaccag
ctggtgatcatgttgatcgatgagctctgtggtccagacccttccctgtcggaagagctg
acctccatcctcatcgagctcactcagctgagcaagagcgagcattgcaaagtggccctc
agagccagacaggtcctgatcgcctcccacctcccgtcctacgagctgaggcacaaccag
gtggagtccattttcctgtctgccatcgacatgtatggccaccagttctgcccagaaaac
ctcaagaaactaatactctctgaaacgaccatatttgatgtcctgcccactttcttctac
catgctaataaagtcgtctgcatggcatccttggaggtttatgtgcgacggggctacatt
gcctatgagttaaacagtttgcagcaccgggagctcccagatggcacctgcgtggtggag
ttccagttcatgttgccctcctcccacccaaacaggatggccgcgcccatcagcatcacc
aaccccgatctgctgaggcacagcaccgagctcttcatggacagcggcttctccccaccg
tgccagcggatgggggccatggtcgccttcaggagatttgaggactttgtaaggaatttt
gatgaagtcatcttctgctttgccaatgtgccccaggaagcccccctcctcagcaaggcc
tgcacttccctgtactgtgaggaagacagcaagaacctcagagaagagccaatccacatc
ctcaacgtggccatccagcacgcggaccacctggaagatgaggagctggtgccgattttc
cggacgttcgtacagtccaagaaaaacatccttgtggattatggactccgaagaatcaca
ttcctgattgcccaagagaaagaatttcccaagtttttcacgtttagagcaagagatgag
tttgcagaagatcgcatttaccgtcacctggagcctgccctggcctaccagctggaactc
agtcggatgcgcagcttcgatcttaccgcagtgccctgcgccaaccacaagatgcacctg
tacctgggcgccgccaaagtgaaagaaggggcagaagtgacagattacaggttcttcatc
cgcgccatcatcaggcactcggacctcattacaaaggaagcctcctttgagtacctgcag
aacgagggtgagcgtctgctcctggaggccatggatgagctggaggtggctttcaacaac
accaacgtgcgcactgactgcaaccatatcttcctgaacttcgtgcccaccgtcatcatg
gacccctccaagattgaggagtccgtgcgttccatggttatgcgctatggcagtcggctg
tggaaactccgtgtgctgcaggctgaggtcaagatcaacatccgccagaccaccgctggc
aatgctgttcccatccgcctgttcatcaccaatgagtcaggctactacctggacatcagc
ctctacaaagaagtcaccgaccccagatctggaaatatcatgtttcactcctttggtgac
aaacagggaccccagcacgggatgctgatcaacactccctatgtcaccaaggatctgctt
caggccaagcgattccaggcccagtccctgggcaccacctacgtctatgacttcccagag
atgttcaggcaggctctctttaaactgtggggcaccccagacaagtaccctaaggacatc
ctgacatacactgaactcgtgctggatccccagggccagctagtggagatgaaccgcctt
cctgggggaaatgaggtgggcatggtggccttcaaaatgaggttcaagactccggagtat
ccggaagggcgggacgtgatcgtcatcagcaatgacatcacgttccgaattgggtccttt
ggcatgggagaagacctcctgtacctgcgggcatcggagatggcccgggcagagggcatc
ccaagaatctacctcgcagccaacagtggggccggtatcggcctcgcagaggagatcaag
catatattccaggtggcttgggtggacccaggagaccccaacaaaggatttaagtacttg
tacctgaccccccaagactacaccacagtcagctccctgaattctgtccactgtaaacac
atcgaggaagacggagaatccaggtatgtcatcacggatatcatcgggaaggacagtggt
gtgggcgtagagaatctcaggggctccggcatgattgcgggggagtcttccctggcttat
gaagagatagtcaccatcagcttggtgacctgccgagctgtggggattggggcctacttg
gtgaggctgggccagcgagtcatccaggtggaaaactctcacatcatcctgacgggagcc
agcgcgctaaacaaggtcctgggccgagaggtgtacacctccaacaaccagctgggcggc
gtgcagatcatgcattacaacggcgtctcccacaccactgtgccggacgacttcgagggc
gtgtacaccatcctggagtggctgtcctatatgccaaaggataatcacagcccagtcccc
atcatcacacccactgaccccattgaccgagaagttgggtactacccgaccaaggctccg
tatgacccccggtggctgcttgcaggaaagcctcacccgactctgaagggatcctggcag
agtggattcttcgaccatggcagtttcaaggaaatcatggcaccttgggcccagactgtg
gtaacaggacgagcaaggctggggggtatccctgttggagtgatcgccgtggagacgcgg
accgtggaggtggtgattcctgcggaccctgccaacctggattcagaggcgaagataatc
cagcaggtgggccaggtgtggctcccagactcggcctacaagacagcccaggccatcaag
gattttaaccgagagaagttgcccctgataatctttgccaactggagggggttctccggt
ggcatgaaagacatgtacgaccagatgctaaagttcggagcctacatcgtggacagcctc
aggcagtataaacagcccatcctgtcctatatcccacccaacgcagagctccggggaggc
tcctgggtggtcatggactcctccatcaaccccctgtgcatagaattgtacgcagacaag
gaaagcagggcgaatattctggagccggagggaacggtggagattaagtacagaaagaaa
gatctgatcaagaccatgagaaggattgacccaacttacaagaagctcgtggaacagcta
ggaacaccagggctctcggacaaggaccgcaaggacctggagggccagctgaaggcccgg
gagcaactgctgctgcccatctatcaccaggtggcggtgcagttcgccagcctccacgac
aagcccatctgcatgctggagaagggtgccctcgctgacatcttggaatggaagacctca
cgcacctttctgtattggcgcctgcgccgcctcctgctggaggaccagatcaggcaggag
atcctgcaggccagccctgagctgagccacgtgcacatccagtccatgctgcggcgctgg
ttcgtggagaccgagggggccgtcaaggcctacatgtgggacaataaccagatggtggta
cggtggctggaacagcactggcaggcgggggacagcctgcactccaccatccgcgagaac
atcaagtgcctaaagcgtgactccgtcctcaaggccatcagaggcctggtacaggacaat
ccagaagtagccgcggactgtattgtgtacatgagccagcacgtcagcccagccgagcgg
gcacaagtcattcaccttttgtccaccatggacagcccagcctccacctga
DBGET
integrated database retrieval system
