Mustela nigripes (black-footed ferret): 132025399
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Entry
132025399 CDS
T09425
Symbol
PSEN2
Name
(RefSeq) presenilin-2 isoform X1
KO
K04522
presenilin 2 [EC:3.4.23.-]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04330
Notch signaling pathway
mnp04722
Neurotrophin signaling pathway
mnp05010
Alzheimer disease
mnp05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
132025399 (PSEN2)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
132025399 (PSEN2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
132025399 (PSEN2)
05022 Pathways of neurodegeneration - multiple diseases
132025399 (PSEN2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mnp01002
]
132025399 (PSEN2)
Peptidases and inhibitors [BR:
mnp01002
]
Aspartic peptidases
Family A22: presenilin family
132025399 (PSEN2)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Presenilin
Homeodomain
Motif
Other DBs
NCBI-GeneID:
132025399
NCBI-ProteinID:
XP_059268579
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Position
10:complement(12081708..12106321)
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AA seq
491 aa
AA seq
DB search
MLTFMASDSEEEVCDERTSLMSAESPPPRCCQEARQGLEDRESAAQWFQNTRARHRRAHH
GGVPWPSPSGFPQRSQDSEEDLDEDADRYMCSGVPGQPSGLEEELTLKYGAKHVIMLFVP
VTLCMVVVVATIKSVRFYTEKNGQLPYGAGREQSLQPAISLSIYTPFTEDTPSVGQRLLN
SVLNTLIMISVIVAMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNV
AMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILG
AISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQL
PYDPEMEEDSYDSFGEPSYPEVFEPPLPGYPGDELEEEEERGVKLGLGDFIFYSVLVGKA
AATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPF
MDTLASHQLYI
NT seq
1476 nt
NT seq
+upstream
nt +downstream
nt
atgctcacgttcatggcctctgacagtgaggaagaagtgtgtgacgagaggacgtccctg
atgtcggctgagagccccccaccacgctgctgccaggaggcccggcagggcctggaggac
agagagagtgctgcccaatggttccaaaatacccgtgcccggcaccgcagagcccaccac
gggggcgtgccatggccctcaccgagcggttttccgcagagaagccaggatagcgaggag
gacctcgacgaggatgccgaccgctacatgtgcagtggggtccccgggcagccatcgggc
ctggaggaggagctgaccctcaaatatggggcaaagcacgtgatcatgctgtttgtgcct
gtgacgctttgcatggttgtagtggtggccaccatcaagtccgtgcgcttctacacggag
aagaacggccagctgccctatggagcaggcagggagcagagtctgcagcccgccatctcc
ctcagcatctacacaccattcaccgaggacacgccctctgtgggccagcgcctgctcaac
tctgtcctcaacaccctcatcatgatcagtgtcatcgtggccatgaccatcttcctggtc
gtgctctacaagtaccgctgctacaagttcatccatggctggttgatcatgtcctccctg
atgctgctgtttctcttcacctacatctacctcggggaagtgctcaagacctataacgtg
gccatggactaccccaccctgttcctgactgtctggaacttcggggcagtgggcatggtg
tgcatccactggaagggccccctcgtgctgcagcaggcctacctcatcatgatcagtgct
ctcatggccttggtgttcatcaagtacctcccggaatggtccgcctgggtcattctgggc
gccatctctgtgtacgatcttgtggctgtgctgtgccccaaggggccgctgaggatgctg
gtggagaccgcccaggagaggaacgagcccatatttcctgccctgatatactcctccgcc
atggtgtggacggtgggcatggccaagctggacccctcctcccagggagcccttcagctg
ccctacgaccctgagatggaagaagactcctatgacagctttggggagccctcgtacccc
gaggtctttgagccccccctgcctggttacccaggggacgagctggaggaagaggaggaa
aggggcgtgaagctcggcctgggggacttcatcttctacagcgtgctggtgggcaaggcg
gcagccacgggcagcggggactggaacaccacgctggcatgcttcgtggccatcctcatt
ggtttgtgtctgaccctcctgctgcttgctgtgttcaagaaggcgctgcccgccctcccc
atctccatcacgttcgggctcatcttctacttctccaccgacaacctggtgcgtccgttc
atggacaccttggcttctcatcagctctacatctga
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