Mustela nigripes (black-footed ferret): 132026555
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Entry
132026555 CDS
T09425
Name
(RefSeq) insulin receptor substrate 2-like isoform X1
KO
K17445
insulin receptor substrate 3
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04022
cGMP-PKG signaling pathway
mnp04068
FoxO signaling pathway
mnp04081
Hormone signaling
mnp04140
Autophagy - animal
mnp04152
AMPK signaling pathway
mnp04211
Longevity regulating pathway
mnp04213
Longevity regulating pathway - multiple species
mnp04910
Insulin signaling pathway
mnp04920
Adipocytokine signaling pathway
mnp04923
Regulation of lipolysis in adipocytes
mnp04930
Type II diabetes mellitus
mnp04935
Growth hormone synthesis, secretion and action
mnp05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
132026555
04022 cGMP-PKG signaling pathway
132026555
04152 AMPK signaling pathway
132026555
09133 Signaling molecules and interaction
04081 Hormone signaling
132026555
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
132026555
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
132026555
04923 Regulation of lipolysis in adipocytes
132026555
04920 Adipocytokine signaling pathway
132026555
04935 Growth hormone synthesis, secretion and action
132026555
09149 Aging
04211 Longevity regulating pathway
132026555
04213 Longevity regulating pathway - multiple species
132026555
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
132026555
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
132026555
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Motif
Pfam:
IRS
Motif
Other DBs
NCBI-GeneID:
132026555
NCBI-ProteinID:
XP_059270537
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Position
11:7229124..7232298
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AA seq
513 aa
AA seq
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MKPGGGGPTAAPESDLADRPLVLPRPWACPADVRLCGHLRKQKSQRRRFFVLRADPPRLE
CYESEKKFRAGRAPPKLSVSLAGACTISKRVDARQRHLIVLYTRDHSLGVAAACEAEQQA
WYLALLEARAAAGPSLHEDPGAWILAPFQDVWPVTLRPKGLGRTQGLGSGRYRLCLGSGV
LSLLRKPKGRGSGDTQASPPPPALRLSLLSVRRCGHADSFFFLELGRSAPTGPGELWLQA
PDALVAQSIHETVLAAMKRLGEGGATGRAEPLPRDPPTGAYRPSASQSSPTLASTAQSSG
GSPRGGLGERNRKTLQMLAKAASHPKDLELGGGYVAMGAGSNYEPMGGGEAGGYMVMAPP
GLAASAHATPHDQLQVCQGTEYVPMSRFLPGSLFSSSLPGSSELGAGESGPSFQGPRRSL
GECWGPAGAHPSLQPPSELAGEYVCIKYVAPDYLGMGTATQEPPNGRLNYADLDLIPSLE
VRGDSRNPQHSYARIEFQNLREAPVRCGQLRPV
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgaagcccggaggcggtggccccacggcggccccggagtccgacctggcggacaggccg
ctggttctgccgcggccctgggcctgtccggctgacgtacggctctgcggccacctgcgg
aagcagaagtcgcagcgccgccgcttcttcgtgctccgcgccgacccgccgcgcctcgag
tgctacgagagcgagaagaagttccgcgcgggccgagcgccgcccaagctcagcgtgagc
ctggcgggcgcgtgcaccatcagcaagcgcgtggacgcgcgccagcgccacctgatcgtc
ctctacacgcgcgaccacagcctgggcgtggcggcggcctgcgaggcggagcagcaggcg
tggtacctcgccctgctggaggcgcgcgcggccgcgggtcccagcctccacgaggacccc
ggcgcctggattctcgctccgtttcaggacgtctggcccgtgacgctgcggcccaaggga
ctggggcgaacacaaggcctgggcagcggccgctaccgcctgtgcctgggttcgggggtg
ctgagcctgctgcggaagcccaaaggcagaggctctggggacacccaggcttcgcctccg
ccgcccgccctgcgcctgtccctgctcagtgtgcgccgctgcggccacgcagactccttc
ttcttcctggagctcggccgctcggcgcccacgggtcccggggagctgtggctacaggcg
cccgacgccctggtggcccaaagcattcatgagactgtactggccgccatgaagcgactc
ggggagggcggtgccactggcagggctgagccactgccaagggatcccccgaccggcgct
tacagaccctctgcctcccaatcttctccgaccctggcctcgacagcccagtcaagtggc
gggagccctcgcggaggcctcggggagagaaacaggaaaaccctccagatgctggcaaag
gcagcctcgcaccccaaggacttggagctgggagggggctacgtagccatgggagccggg
agcaactatgagcccatggggggtggcgaagcaggtggctacatggtgatggcaccccct
ggccttgcggcctctgcccacgcaactccccacgaccaactccaagtttgccagggcact
gaatacgttcccatgagccgctttctgccagggtccttgttctccagctccctgcccggc
tcctctgagctcggagctggggagtctggaccttcctttcaaggaccccgtcgcagcctg
ggggaatgttggggaccagcaggggcgcatccctccttgcagccgccctcagagctagca
ggggagtacgtgtgcatcaagtatgtggcccctgactacttaggaatgggcactgccaca
caagaaccccccaacggccgcctcaattacgctgacctggacctgatcccttcactggag
gttcgaggcgacagcaggaacccacaacacagctatgcccgcatcgagttccagaacctc
agggaggctccggtgagatgtgggcagctccgccctgtctag
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