KEGG   ORTHOLOGY: K17445
Entry
K17445                      KO                                     
Symbol
IRS3
Name
insulin receptor substrate 3
Pathway
map04022  cGMP-PKG signaling pathway
map04068  FoxO signaling pathway
map04081  Hormone signaling
map04140  Autophagy - animal
map04152  AMPK signaling pathway
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04910  Insulin signaling pathway
map04920  Adipocytokine signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04930  Type II diabetes mellitus
map04935  Growth hormone synthesis, secretion and action
map05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K17445  IRS3; insulin receptor substrate 3
   04022 cGMP-PKG signaling pathway
    K17445  IRS3; insulin receptor substrate 3
   04152 AMPK signaling pathway
    K17445  IRS3; insulin receptor substrate 3
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    K17445  IRS3; insulin receptor substrate 3
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K17445  IRS3; insulin receptor substrate 3
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K17445  IRS3; insulin receptor substrate 3
   04923 Regulation of lipolysis in adipocytes
    K17445  IRS3; insulin receptor substrate 3
   04920 Adipocytokine signaling pathway
    K17445  IRS3; insulin receptor substrate 3
   04935 Growth hormone synthesis, secretion and action
    K17445  IRS3; insulin receptor substrate 3
  09149 Aging
   04211 Longevity regulating pathway
    K17445  IRS3; insulin receptor substrate 3
   04213 Longevity regulating pathway - multiple species
    K17445  IRS3; insulin receptor substrate 3
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K17445  IRS3; insulin receptor substrate 3
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K17445  IRS3; insulin receptor substrate 3
Genes
PANU: 101021880
MMUR: 105868385
LCAT: 123631629
PCOQ: 105806007
MMU: 16369(Irs3)
MCAL: 110293997
RNO: 84021(Irs3)
MCOC: 116068604
ANU: 117698147
ASYL: 127672611
MUN: 110556773
CGE: 100751390
MAUA: 101835091
PROB: 127237201
PLEU: 114686777
MORG: 121446140
MFOT: 126493980
AAMP: 119824895
NGI: 103733517
CCAN: 109698062
DORD: 106002856
DSP: 122113664
PLOP: 125367642
NCAR: 124970787
MMMA: 107146610
ITI: 101975126
OCU: 100339305
OPI: 101525112
TUP: 106735628
AML: 100467269
UMR: 103670034
UAH: 113267858
UAR: 123777346
ELK: 111146232
LLV: 125090697
MPUF: 101671264
MNP: 132026555
MLK: 131820117
NVS: 122896052
ORO: 101378833
EJU: 114214389
ZCA: 113932642
MLX: 117999416
NSU: 110571849
LWW: 102749360
FCA: 101100432
PYU: 121017634
PCOO: 112859926
PBG: 122471292
PVIV: 125154378
LRUF: 124519412
LGF: 123589726
AJU: 106987435
PTG: 102952104
PPAD: 109251297
PUC: 125928238
PLEZ: 122210266
HHV: 120223687
BTA: 107131843(IRS3)
BOM: 138985564
BIU: 109578427
BBUB: 102404040
BBIS: 104987149
OAS: 101121655
BTAX: 128043668
CSUM: 138075648
ODA: 120879389
CCAD: 122432714
MREE: 136158593
OVR: 110126493
MBEZ: 129545680
SSC: 100515824
CFR: 116657470
CBAI: 105078567
CDK: 105105271
VPC: 102538912
BACU: 103005013
BMUS: 118881371
OOR: 101279800
LALB: 132504817
DLE: 111181964
PCAD: 102982336
PSIU: 116740211
NASI: 112399963
ECB: 100069009
EPZ: 103555632
EAI: 106839324
HAI: 109374927
RFQ: 117024512
MJV: 108409367
TOD: 119242334
SARA: 101548071
SFUM: 130036538
SETR: 126029954
LAV: 100660353
TMU: 101362072
MDO: 103100498
GAS: 123246324
OAA: 114808089
HRO: HELRODRAFT_171842
 » show all
Reference
PMID:9348224
  Authors
Sciacchitano S, Taylor SI
  Title
Cloning, tissue expression, and chromosomal localization of the mouse IRS-3 gene.
  Journal
Endocrinology 138:4931-40 (1997)
DOI:10.1210/endo.138.11.5518
  Sequence
[mmu:16369]
Reference
PMID:11724774
  Authors
Kabuta T, Hakuno F, Asano T, Takahashi S
  Title
Insulin receptor substrate-3 functions as transcriptional activator in the nucleus.
  Journal
J Biol Chem 277:6846-51 (2002)
DOI:10.1074/jbc.M107058200
  Sequence
[rno:84021]
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