Mycobacterium noviomagense: MNVI_43550
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Entry
MNVI_43550 CDS
T06809
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
mnv
Mycobacterium noviomagense
Pathway
mnv00270
Cysteine and methionine metabolism
mnv00450
Selenocompound metabolism
mnv00670
One carbon pool by folate
mnv01100
Metabolic pathways
mnv01110
Biosynthesis of secondary metabolites
mnv01230
Biosynthesis of amino acids
mnv04980
Cobalamin transport and metabolism
mnv04981
Folate transport and metabolism
Module
mnv_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
mnv00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
MNVI_43550 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
MNVI_43550 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
MNVI_43550 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
MNVI_43550 (metH)
04980 Cobalamin transport and metabolism
MNVI_43550 (metH)
Enzymes [BR:
mnv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
MNVI_43550 (metH)
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BBY09037
UniProt:
A0A7I7PK76
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All DBs
Position
complement(4550618..4554208)
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AA seq
1196 aa
AA seq
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MLVRVTFSNDHAYDTDLLDTLAQRVMVGDGAMGTQLQAAELTLDDFRGLEGCNEILNETR
PDVIETIHRNYFEAGAEAVETNTFGCNLSNLGDYDIADKIRDLAHRGTAIARRVADELST
QQRKRYVLGSMGPGTKLPTLGHTEYALIRDAYTEAALGMLEGGADAVLVETCQDLLQLKA
AVLGARRAMTQAGRHIPVITHVTVETTGTMLLGSEIGAALTAIEPLGVDMVGLNCATGPA
EMSEHLRYLSRHARIPVSVMPNAGLPVLGANGAEYPLQPDELAEALAGFIAEFGVALVGG
CCGTTPDHIRQVAEAVRTVTPAQRQITYEPAVSSLYTSVPFKQEASVLVIGERTNANGSK
AFREAMIAEDYQKCLDIAKEQTRDGAHLLDLCVDYVGRDGAADMTALASRLATASTLPIM
LDSTETAVLRAGLEHLGGRCAINSVNYEDGDGPDSRFHKTMELVAEHGAAVVALTIDEEG
QARTADKKVAIAGRLIDDITRNWGVDESSILIDCLTFTIATGQEESRRDGIETIEAIREL
KKRHPNVQTTLGLSNISFGLNPAARQVLNSVFLHECQEAGLDSAIVHASKILPINRIPED
QRTVALDLVYDRRRDGYDPLQELMGMFEGVSAASSKESRAAELAKLPLFERLAQRIVDGE
RNGLEADLDEAMTQKAPLAIINEDLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYL
EPHMEKSEDDQGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNLGIKQPIGNILEVA
EDKSADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEVYE
GEVHYARDAFEGLKLMDTIMSAKRGEAPDTDSPEAIAAREKEAERKARHERSKRIAAQRK
AAETPIEVPERSDVAADVEVPTPPFWGSRIVKGLAVADYSALLDERALFLGQWGLRGARG
GKGPSYEELVETEGRPRLRYWLDRLSTDGVLAHAAVVYGYFPAVSERDDVIILTEPTPDA
PERFRFTFPRQQRDRFLCIADFVRPRSLATERGQVDVLPFQLVTMGDPIADFANKLFASN
SYRDYLEVHGIGVQLTEALAEYWHRRIREELRFSGDRAMSSEDPESVEDYFKLGYRGARF
SFGYGACPDLEDRVKTMALLQPDRIGVSLSEEMQLHPEQSTDAFILHHPEAKYFNV
NT seq
3591 nt
NT seq
+upstream
nt +downstream
nt
atgcttgtccgggtgactttctccaacgatcacgcctacgacaccgacttactcgacacc
ttggcgcagcgcgtcatggtgggcgacggcgccatgggcacccagctgcaggccgcggag
ctgacgctcgacgacttccgcggcctggagggctgcaacgagatcctcaacgagactcgc
cccgacgtgatcgagaccatccaccgcaactacttcgaggccggcgccgaggcggtggag
accaacaccttcggctgcaacctgtccaacctcggcgactacgacatcgccgacaagatc
cgcgacctcgcacaccgcggcaccgcgatcgcgcggcgggtggccgacgagctttccacg
cagcagcgcaaacgctacgtgctgggctcgatgggaccgggcaccaagctgcccaccctc
ggccacaccgaatacgcgctgatccgcgacgcctacaccgaggcggcgctgggcatgctc
gagggcggcgcggacgccgtcctggtggagacctgccaggacctgctgcagctcaaggcg
gcggtgctgggggcacggcgggcgatgacgcaggccgggcggcacatcccggtgatcacc
cacgtcaccgtagagaccaccggcaccatgttgctgggcagcgagatcggggcggcgctg
accgcgatcgagccgctcggtgtcgacatggtcggcctgaactgcgccaccgggcctgcc
gagatgagcgagcacctgcgctacctgtcgcggcacgcccgcatcccggtgtcggtgatg
cccaacgcgggcctgcctgtgctgggcgccaacggcgccgaatacccgctgcagcccgac
gagctggccgaggccctggccggattcatcgccgagttcggagtcgcgctggtcggcggc
tgctgcggcacaaccccagaccacatccgccaggtcgccgaggccgtgcgcaccgtcacc
cccgctcagcggcagatcacctacgagccggcggtgtcctcgctgtacacctcggtcccg
ttcaagcaagaggcgtcggtgctggtcatcggggaacgcacaaacgccaacggctccaag
gctttccgtgaggcgatgatcgccgaggattaccagaagtgtctggacatcgccaaggag
cagacccgcgacggggcacatctgctggacctgtgcgtcgactacgtgggccgcgatggg
gcggccgacatgaccgcgctggccagccggctggccaccgcgtcgacgctgccgatcatg
ctggactccaccgaaaccgccgtgctgcgagcgggtttggagcacctaggcgggcgctgt
gctatcaactcggtcaattacgaagacggcgacggccctgactcccggttccacaagacc
atggaactggtcgccgagcacggcgcagcggtggtcgcgctgaccatcgacgaagagggc
caggcccgcaccgccgacaagaaggtggcgatcgccggacggctgatcgacgacatcacc
cgcaactggggtgtcgatgagtcctccatcctcatcgactgcctgaccttcaccatcgcc
accggacaggaggagtcgcgccgcgacggcatcgagaccatcgaggcgatccgcgaactg
aagaaacgccacccgaacgtgcaaaccacgctcgggttgtccaacatctcgttcgggctc
aatcccgctgcgcgccaagtgctcaactcggtgttcctgcacgaatgccaggaagcgggg
ctggattcggcgatcgtgcacgcgtcgaagatcctgccgatcaaccggattccggaagac
cagcgcacggtggcgctggatctggtctacgaccgccgccgcgacggctatgacccactg
caagagctgatgggcatgttcgagggcgtgtcggcggcgtcgtcgaaagaatcccgcgcc
gccgagttggccaagctgccgttgttcgagcgattggcgcagcggatcgtcgacggcgag
cgcaacggcctggaagccgatctcgacgaggcgatgacccagaaggcgccgctggccatc
atcaacgaggacctgctggccggcatgaaaaccgttggggagctgttcggttcgggtcag
atgcagctgccgttcgtgctgcagtcggccgaggtgatgaaagccgcggtggcctatctt
gaaccgcacatggagaagtccgaggacgaccaaggcaagggccggatcgtgctggcgacc
gtcaagggcgacgtgcacgacatcggcaagaacctcgtcgacatcatcttgagcaacaac
ggctacgaagtcgtcaacctcggcatcaagcagccgatcggcaacatcctcgaagtcgcg
gaagacaagagcgccgatgttgtcggcatgtcggggttgctggtgaaatccactgtggtg
atgaaggaaaacctcgaggagatgaacacccggggggtcgccgagaagttcccggtgctg
ctcggcggcgcggcgttgacccgcagctacgtggaaaacgacctcgccgaggtctatgag
ggcgaagtgcattacgcccgcgatgcgttcgagggcctgaagttgatggacaccatcatg
agcgccaagcggggggaggcgcccgacaccgacagcccggaggcaatcgcggcccgcgaa
aaggaagccgaacgcaaggcccgccacgagcgctcgaaacgcattgcggcacaacgcaaa
gcagctgagacgccgatcgaggtacccgagcgctccgacgtcgcagccgacgtcgaggtg
ccgacgccgccgttctgggggtcgcggatcgtcaagggcctggctgttgccgactacagc
gcgttgctcgacgagcgtgctttgttcctgggccagtggggcctgcgcggtgcacgcggc
ggcaaaggcccgtcctatgaagagctggtggagaccgaagggcggccgcggttgcgctac
tggctggaccggctgtcgactgacggggtgctggcgcacgccgcggtggtgtacggctac
ttcccggcggtctccgagcgcgacgacgtcatcatcctcactgaaccgacaccggatgcg
ccggagcggttccggttcaccttcccgcgccagcaacgcgaccggttcctctgtatcgcg
gacttcgtcaggccacggtcactggccaccgaacgtggccaggttgacgtcctgcccttc
cagctggtgacgatgggcgatccgatcgccgacttcgccaataagctgttcgcctccaac
tcctaccgcgactacctcgaggtgcacggcatcggcgtgcagctcaccgaggcgctggcc
gagtactggcaccgacggatccgcgaggagctgcgcttctccggcgatcgggcgatgtcc
agcgaggacccggaatctgtggaggactacttcaagctgggctaccgtggcgcccggttc
tcgttcggctatggcgcctgccctgacctggaggaccgggtcaagaccatggcgctgctg
cagccagaccgcatcggggtgagcctgtcggaggagatgcagctgcatcccgagcagtcc
accgatgcgttcatcctgcatcaccccgaggccaagtacttcaacgtctga
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