Mycobacterium noviomagense: MNVI_45110
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Entry
MNVI_45110 CDS
T06809
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mnv
Mycobacterium noviomagense
Pathway
mnv00010
Glycolysis / Gluconeogenesis
mnv00020
Citrate cycle (TCA cycle)
mnv00620
Pyruvate metabolism
mnv00785
Lipoic acid metabolism
mnv01100
Metabolic pathways
mnv01110
Biosynthesis of secondary metabolites
mnv01120
Microbial metabolism in diverse environments
mnv01200
Carbon metabolism
mnv01210
2-Oxocarboxylic acid metabolism
Module
mnv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mnv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MNVI_45110 (aceE)
00020 Citrate cycle (TCA cycle)
MNVI_45110 (aceE)
00620 Pyruvate metabolism
MNVI_45110 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MNVI_45110 (aceE)
Enzymes [BR:
mnv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MNVI_45110 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
BBY09193
UniProt:
A0A7I7PKM4
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Position
4704672..4707473
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AA seq
933 aa
AA seq
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MTTEFVRHDLAKNSSNTSEHDRVRVIREGVASYLPDIDPEETSEWLESFDELLARSGPAR
ARYLLLRMLERAGEQRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIM
VHRAQRPGVSVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAF
LEGRLSADQLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGIGPMNAIYQARFNHY
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVAALEALDNLAFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVIWGREWDALLHADRDGALVNLMNVTPDGDYQTYKANDG
GYVREHFFGRDPRTKDLVKNLSDQEIWNLKRGGHDYRKVYAAYRAAVEHKGQPTVILAKT
IKGYALGKHFEGRNATHQMKKLTLEDLKEFRDTQRIPVSDAQLEEDPYLPPYYHPGPEAP
EIRYMLDRRRALGGFVPERRTKSKALTLPGRDTYKSLKKGSGTQEVATTMATVRTFREVL
RDSGKDGVGHRIVPIIPDEARTFGMDSWFPNLKIYNRNGQLYTSVDADLMLAYKESQAGQ
ILHEGINEAGAVASFTAAGTSYSTHNEPMIPVYIFYSMFGFQRTGDGLWAAGDQMARGFL
LGATAGRTTLTGEGLQHADGHSLLLASTNPAVVSYDPAFAYEVAYIIESGLARMYGENPE
NVFFYITVYNEPYVQPPEPENFDPEGLLRGIYRYRSASEQRANTAQILASGVAMPSALKA
ADMLAAEWDVAADVWSVTSWSELNREGVAIETEKLRHPERPARVPYVTQALTESSGPVIA
VSDWMRAVPEQIRPWVPRRYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAREG
EIDPSVAVAAARQYEIADVRAAPAQTSDPGPGA
NT seq
2802 nt
NT seq
+upstream
nt +downstream
nt
ttgactaccgagttcgtgcgccacgatctggccaaaaactcaagcaacacaagcgaacac
gaccgtgtacgggtgatccgcgaaggggtcgcgtcctacctgccggacatcgaccccgag
gaaacatcggagtggctggagtccttcgacgagttgctggcccgctcggggccggcgcgg
gcacgctatctgcttttgcggatgctggaacgcgccggcgagcaacgggtggcgatcccg
gcgctgacgtcgaccgactacgtcaacaccatccccaccgaactggaaccgtggttcccc
ggcgacgaggacgtcgagcgccgctaccgcgcctggatccggtggaacgcggccatcatg
gtgcaccgcgcccagcgccccggcgtctcggtgggcggccacatctcgacctacgcctcc
tcggcggcgttgtacgaggtcggcttcaaccacttcttccgcggcaagtcccacccgggc
ggcggcgaccaggttttcatccagggccacgcctcccccggcatctacgcgcgcgccttc
ttggaaggacgactgtccgcagatcagctcgacggcttccgtcaggagcacagccatccc
ggcggcgggctgccgtcgtacccgcatccgcggctgatgcccgacttctgggaattcccc
accgtgtcgatgggtatcggcccgatgaacgctatctaccaggcccggttcaaccactac
ctgcacgaccgcggcatcaaagacacctccgatcagcacgtgtggtgcttcttgggtgac
ggcgagatggacgaacccgaaagccgcgggctcgcgcatgtcgccgcgctggaagccttg
gacaacctggccttcgtgatcaactgcaacctgcagcgcctcgacggcccggtgcgcggc
aacggcaagatcatccaggagctcgagtcgttcttccggggtgcgggctggaacgtcatc
aaggtgatctggggccgggagtgggacgcgttgctgcacgccgaccgcgacggcgcgctg
gtcaatctgatgaacgtcacgcccgacggcgactaccagacctataaggccaacgacggc
ggttatgtgcgcgagcatttcttcggccgcgatccgcgcaccaaggatctggtgaaaaac
ctttcggatcaagagatttggaacctcaagcgcggcggtcacgactaccggaaggtgtat
gcggcttaccgcgctgcggtggagcacaagggccagccgaccgtcatcttggccaagacc
atcaagggctacgcgctgggcaagcatttcgagggccgaaacgccacgcatcagatgaaa
aagctgacgctggaagaccttaaagagttccgcgacacccagcgcatcccggtgtcggac
gctcagctcgaagaggatccctacctgccgccgtactaccacccgggcccggaagccccg
gagattcgctacatgctcgaccggcgccgcgcgctcggcgggttcgtgcccgagcgtcgc
accaaatccaaggcgttgacgctgccgggccgcgacacctacaagtcgctgaaaaaggga
tcgggcacccaggaggtcgccaccaccatggcgacggtgcgcacgttccgggaagtgttg
cgcgacagcggaaaagatggagttggtcaccgcatagtcccgatcattcctgacgaggcg
cgcacgttcgggatggactcgtggtttccgaacctcaagatctacaaccgcaacggccag
ctgtacacctcggtcgacgccgatttgatgttggcgtacaaggaaagccaagccggtcag
atcctgcacgagggcatcaacgaagccggggcggtggccagcttcaccgcggcgggcacg
tcgtactcgacgcacaacgagccgatgatcccggtctacatcttctattcgatgttcggt
tttcagcgcaccggcgacggcctgtgggcagcgggcgatcagatggcgcgcggattcctg
ctgggcgccaccgccggacgcaccacgctcaccggcgaaggcctgcagcacgccgacggc
cactcgctgttgctggccagcaccaacccggcggtggtctcctacgatccggccttcgcc
tacgaggtcgcgtacatcatcgaaagcggcctggctcgcatgtacggcgagaacccggaa
aacgtcttcttctacatcaccgtctacaacgagccgtatgtccagccgcccgagccggag
aacttcgaccccgaaggtctgctgcgcggcatctaccggtaccggtcggccagcgagcag
cgcgccaacaccgcccagatcctggcgtccggggtcgctatgccgtcggcgctgaaagcc
gccgacatgttggccgccgagtgggatgtcgccgccgacgtgtggtcggtgaccagttgg
agcgagttgaaccgcgaaggggtggccatcgagaccgagaagctgcgccacccggagcgt
ccggcgcgggtgccctatgtgacgcaggcgctgaccgaatccagcgggccggtgatcgcc
gtgtcggactggatgcgggcggttcctgagcagatccggccctgggtgccgcggcgctac
gtcacgttgggcaccgacgggttcggtttctccgatacccggcccgccgcccggcgctac
ttcaacaccgacgcggagtcccaagttgtggcggtgctggaggcgctggcccgagagggc
gagatcgacccgtcggtggccgtcgcggcggcacggcaatacgagatcgccgacgtgcgg
gccgcgccggcgcagacgtctgacccgggccccggcgcctag
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