KEGG   Moritella sp. 36: HWV03_09180
Entry
HWV03_09180       CDS       T08847                                 
Symbol
dfrA
Name
(GenBank) trimethoprim-resistant dihydrofolate reductase DfrA
  KO
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
moq  Moritella sp. 36
Pathway
moq00670  One carbon pool by folate
moq00790  Folate biosynthesis
moq01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:moq00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    HWV03_09180 (dfrA)
   00670 One carbon pool by folate
    HWV03_09180 (dfrA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:moq01504]
    HWV03_09180 (dfrA)
Enzymes [BR:moq01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     HWV03_09180 (dfrA)
Antimicrobial resistance genes [BR:moq01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    HWV03_09180 (dfrA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: QUM88954
LinkDB
Position
2036674..2037171
AA seq 165 aa
MKLSLMAAKSLNGIIGNGPDIPWRAKGEQLLFKAMTYNQWLLVGRKTFESMGSLPNRKYA
VISRSDFVSEDENVMVFSSIEGALKELEDITDHVIVSGGGEIYRSLISKVDTLHISTIDI
ETEGDIVFPEIPGSFSLAFEQKFESNINYCYQIWQKSEEAVVPSV
NT seq 498 nt   +upstreamnt  +downstreamnt
atgaagttatcattaatggctgcaaagtctctgaatggcatcattggcaatggtcctgat
attccatggagagctaaaggtgagcaacttttattcaaagccatgacatataatcaatgg
cttttagttggacgcaaaacttttgagtctatggggtcgctaccaaatcgtaagtacgcc
gtgatatcacgatctgatttcgtttcagaggatgaaaatgtaatggttttctcttcaatt
gagggggctttaaaagagttagaagatattaccgatcacgttattgtttcgggtggcggc
gagatttatagaagtttgatttctaaagttgatactttgcatatatcaacaattgatatt
gaaactgaaggggatattgtttttcctgaaatccctggttcatttagtttagcgtttgag
caaaaatttgaatcgaatattaactattgctatcaaatttggcaaaagagtgaagaagcc
gttgtaccgagtgtttaa

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