Microtus oregoni (creeping vole): 121445850
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Entry
121445850 CDS
T08307
Symbol
Ptpn11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg04014
Ras signaling pathway
morg04072
Phospholipase D signaling pathway
morg04148
Efferocytosis
morg04360
Axon guidance
morg04625
C-type lectin receptor signaling pathway
morg04630
JAK-STAT signaling pathway
morg04650
Natural killer cell mediated cytotoxicity
morg04660
T cell receptor signaling pathway
morg04670
Leukocyte transendothelial migration
morg04722
Neurotrophin signaling pathway
morg04920
Adipocytokine signaling pathway
morg04931
Insulin resistance
morg05168
Herpes simplex virus 1 infection
morg05205
Proteoglycans in cancer
morg05208
Chemical carcinogenesis - reactive oxygen species
morg05211
Renal cell carcinoma
morg05220
Chronic myeloid leukemia
morg05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
121445850 (Ptpn11)
04630 JAK-STAT signaling pathway
121445850 (Ptpn11)
04072 Phospholipase D signaling pathway
121445850 (Ptpn11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
121445850 (Ptpn11)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
121445850 (Ptpn11)
04660 T cell receptor signaling pathway
121445850 (Ptpn11)
04670 Leukocyte transendothelial migration
121445850 (Ptpn11)
09156 Nervous system
04722 Neurotrophin signaling pathway
121445850 (Ptpn11)
09158 Development and regeneration
04360 Axon guidance
121445850 (Ptpn11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
121445850 (Ptpn11)
05208 Chemical carcinogenesis - reactive oxygen species
121445850 (Ptpn11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
121445850 (Ptpn11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
121445850 (Ptpn11)
05211 Renal cell carcinoma
121445850 (Ptpn11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
121445850 (Ptpn11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
morg01009
]
121445850 (Ptpn11)
Enzymes [BR:
morg01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
121445850 (Ptpn11)
Protein phosphatases and associated proteins [BR:
morg01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
121445850 (Ptpn11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
Y_phosphatase3
PTPlike_phytase
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
121445850
NCBI-ProteinID:
XP_041503941
LinkDB
All DBs
Position
Unknown
AA seq
597 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW
QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI
DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK
RKGHEYTNIKYSLVDQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQRSFR
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcaccccaacatcactggtgtggaggcagagaatctcctg
ctgaccagaggagtcgatggcagttttttggcaaggcccagtaagagtaaccctggagac
ttcactctgtccgttagacgaaatggagccgttacccatatcaagattcagaacactgga
gactactatgacctctatggtggggagaagtttgccacattggctgaactggtccagtat
tacatggagcatcatgggcagctgaaagagaagaatggagatgttattgagctcaagtac
ccactgaactgtgcagacccaacctctgaaaggtggttccatggtcacttgtctggaaaa
gaagcagagaaactgctaacggagaagggtaagcatggcagctttcttgtccgagagagc
cagagccaccctggagactttgttctctccgtccgcaccggtgatgacaaaggggagagc
aatgatggcaagtccaaagtgacccacgtcatgatccgatgtcaggaattgaaatacgac
gttggtggaggagagcgctttgactctttgacagacttggtggagcattataagaagaat
cccatggtggagactctgggtaccgtcctgcagctcaagcagcccctcaatacaactcgt
attaatgctgctgaaatcgaaagccgtgttcgagagctaagcaagctagctgagaccaca
gataaagtcaaacagggcttttgggaagaatttgagacgctacaacaacaggaatgcaaa
cttctctacagtcgaaaagaaggacagagacaagaaaataaaaacaaaaatagatacaaa
aacatcctgccctttgatcacaccagggttgtcctgcatgatggggatcctaatgagccc
gtttctgattacatcaatgcgaatatcatcatgcctgaatttgaaaccaagtgcaacaat
tcaaaacccaaaaagagctacattgctactcaaggctgcctgcagaacacagtgaatgat
ttctggaggatggtgttccaggagaactctcgcgtcattgtcatgaccacaaaggaggtg
gagagagggaagagcaaatgtgtcaagtactggcctgatgagtatgcactcaaagaatat
ggggtcatgcgtgttagaaatgtcaaagaaagtgccgctcatgactacaccttaagagaa
ctcaagctctccaaggttggacaagctctactccagggaaatacagagagaaccgtctgg
cagtaccactttcggacctggccggaccatggtgtgcccagtgaccctggaggtgtgctg
gacttcctggaagaggtccaccacaagcaggagagcatcatggatgcaggccctgttgtg
gttcattgcagtgctggaatcggccggacaggaacattcattgtgattgacatccttatt
gacatcattagagagaaaggtgtggactgtgacattgatgttcctaaaaccattcaaatg
gtgcggtcccagaggtcagggatggtccagacagaagcacagtaccggttcatctatatg
gccgtccaacattacattgagacgcttcagcgcaggattgaggaggagcagaaaagcaaa
aggaaaggacatgaatataccaatattaagtattctctggtggatcagacgagtggcgat
cagagtcccctgccaccttgcaccccaacaccaccctgtgcagaaatgagggaggacagc
gctcgagtctatgagaatgtgggcctcatgcaacagcagaggagcttcagatga
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