Mycobacterium ostraviense: LTS72_08835
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Entry
LTS72_08835 CDS
T07946
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
mot
Mycobacterium ostraviense
Pathway
mot00270
Cysteine and methionine metabolism
mot00450
Selenocompound metabolism
mot00670
One carbon pool by folate
mot01100
Metabolic pathways
mot01110
Biosynthesis of secondary metabolites
mot01230
Biosynthesis of amino acids
mot04980
Cobalamin transport and metabolism
mot04981
Folate transport and metabolism
Module
mot_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
mot00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
LTS72_08835 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
LTS72_08835 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
LTS72_08835 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
LTS72_08835 (metH)
04980 Cobalamin transport and metabolism
LTS72_08835 (metH)
Enzymes [BR:
mot01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
LTS72_08835 (metH)
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
V_ATPase_I_N
Motif
Other DBs
NCBI-ProteinID:
UGT93361
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All DBs
Position
1952562..1956149
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AA seq
1195 aa
AA seq
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MTAANKPSYDTDLLDVLVRRVVVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVL
ESIHRNYFEVGADAVETNTFGCNLSNLGDYDIADKIRDLSEKGTAIARRVADEMGTAERR
RYVLGSMGPGTKLPTLGHTEYAVIRDAYTEAALGMLDGGADAILVETCQDLLQLKAAVLG
SRRAMKQAGRHIPVIAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSE
HLRYLSRHARIPVSVMPNAGLPVLGAKGAEYPLRPDELAEALSGFIAEFGLSLVGGCCGT
TPAHIREVAAAVADVTRPERQVSYEPSVSSLYSAVPFAQDASVLVIGERTNANGSKGFRE
AMIAEDYQRCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALASRLATSSTLPIMLDST
ETPVLQAGLEHLGGRCAINSVNYEDGDGLESRFHKTMELVAEHGAAVVALTIDEEGQART
AEKKVEIAERLIDDITGNWGVDESSILIDTLTFTIATGQEESRKDGIETIEAIRELKRRH
PKVQTTLGLSNISFGLNPAARQVLNSVFLHECQDAGLDSAIVHASKILPMNRIPDEQRKV
ALDLVYDRRRDGYDPLQELMRLFEGVSAASSKESRAAELAKLPLFERLAQRIVDGERNGL
EADLEEAMTQKPPLEIINENLLAGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHM
EKSEDDTGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILEVAEDKS
ADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEIYEGEVH
YARDAFEGLKLMDTIMSAKRGEAPDDDSPEAVKAREKEAERKARHERSKRIAAQRKAAEK
PVEVPDRSDVAADVEVPAPPFWGSRIVKGLAVADYTGMLDERALFLGQWGLRGTRGGPNS
EGPSYEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGDDVVVLTEPAPDAE
ERYRFRFPRQQRGRFLCIADFVRSRELARQRGEVDVLPFQLVTMGKPIADFANELFAANS
YRDYLEVHGIGVQLTEALAEYWHRRIREELRYSADRTMAAEDPDAVEDYFKLGYRGARFA
FGYGACPDLEDRAKMMELLEPDRIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV
NT seq
3588 nt
NT seq
+upstream
nt +downstream
nt
gtgactgccgcgaacaaacccagctacgacactgatctgcttgacgttttggtgcggcgt
gtagtggtgggcgacggcgcgatgggcacccagctgcaggccgccgatctcaccctcgac
gacttccgcggcctggagggctgcaacgagatcctcaacgaaacccgtcctgacgtgctg
gaaagcatccaccgcaactatttcgaagtgggcgcggacgcggtagagaccaacaccttc
ggctgtaacctgtccaacctcggtgactacgacatcgcggacaagatccgcgacctgtcc
gagaagggcaccgcgatcgcccgccgggtggccgacgagatgggcaccgccgagcgcaga
cgctatgtactcgggtcgatgggaccgggcaccaagctgccgaccctgggacacaccgag
tacgccgtcattcgcgacgcctacaccgaggccgccctgggaatgctggacggcggggcc
gacgcgatcctggtggagacctgccaggacctgctgcagctgaaggcggcggtgctcggc
tcgcggcgggcgatgaagcaggccggccgccacattccggtgatcgcccacgtcaccgtg
gaaaccaccggcaccatgctgctgggcagtgagatcggcgcggcgctgaccgcggtcgag
cccctcggtgtggacatgatcggcttgaactgcgcgacgggccccgccgagatgagcgag
cacctgcgctacctgtcccggcacgcccgcatcccggtgtcggtgatgcccaacgccggc
ctgccggtgctgggcgccaagggcgccgagtacccgctgcggcccgacgagctggccgag
gcgctgtccggattcatcgccgagttcgggttgtcgctggtcggcggttgctgcggcacc
acgccggcccacatccgcgaggtggccgccgcggtcgccgacgtcacgcgccccgaacgc
caggtgagctacgagccgtcggtgtcgtcgctgtacagcgcggttccgttcgcgcaggac
gcctcggtgctggtgatcggcgaacgcaccaacgccaacggctccaagggttttcgtgag
gcgatgatcgccgaggactaccagaggtgcctggacatcgccaaggaccagacccgcgac
ggcgcacacctgctggacctgtgtgtcgactacgtcggccgcgacggcgtggccgacatg
aaggccctggcgagccggctggccacgtcgtcgaccctgccgatcatgctggattccacc
gaaaccccggtgctgcaagccggtttggaacacctcggtggccgttgcgcgatcaactcg
gtcaactacgaagacggtgacggactcgagtcgcgcttccacaagaccatggaactcgtc
gccgaacacggcgccgccgtcgtcgcactgaccatcgacgaagagggccaggcccgcacc
gccgagaagaaggtcgagatcgccgagcggctgatcgacgacatcaccggtaactggggc
gtcgacgagtcgtcgattctgatcgacacgctgaccttcaccatcgccaccgggcaggag
gagtcccgcaaagacggcatcgaaaccatcgaggccatccgggaattgaagagacgccac
cctaaggtgcagaccacgctcgggctgtccaacatctcgtttggcctcaatcccgctgcg
cgccaagtgctcaactcggtgttcctgcacgaatgccaggacgccgggctggattcggcg
atcgtgcacgcctcgaagatcctgccgatgaaccggatccccgacgagcaacgcaaggtg
gcgctggatctggtctatgaccgccgccgcgacggctacgacccgctgcaggagctgatg
cgcctcttcgagggggtgtcggcggcgtcgtcgaaggaatcgcgtgccgccgaactcgcc
aagctgccgctgttcgagcggttggcgcaacgcatcgtcgacggcgaacgcaacggccta
gaagccgatctcgaggaggcgatgacgcagaagccgccactggagatcatcaacgagaac
ctgctggccggcatgaagacggtcggtgagctgttcggctcgggccagatgcagctgccg
ttcgtgttgcagtccgccgaggtgatgaagaccgccgtggcgtatctggagccgcacatg
gagaaatccgaggacgacacgggtaagggccggatcgtgctggccaccgtcaagggcgac
gtccacgacatcggcaagaacctggtcgacatcatcttgagcaacaacggctacgaggtg
gtcaacatcggcatcaagcagcccatcgccaccattctcgaggtcgccgaggacaagagc
gccgacgtggtgggaatgtcgggcctgctggtgaaatcgactgtggtgatgaaggaaaac
ctcgaggagatgaatacccggggggtcgccgaaaaattcccggtgttgctcggcggcgcg
gcgttgacccgcagctatgtcgaaaacgatctcgccgagatttatgaaggcgaagtgcac
tatgcgcgtgacgctttcgagggcctcaagctcatggacaccatcatgagtgctaagcgg
ggggaggcgccggacgacgacagccccgaagcggtcaaggcccgcgagaaggaagccgag
cgcaaggcccgtcatgagcgctccaaacgcattgcggcgcaacgtaaagccgctgaaaag
ccggtcgaggttcccgaccgttccgacgtcgcggctgatgtcgaggtgcccgccccgccg
ttctggggttcgcggatcgtcaagggcctggccgtcgccgactacacgggtatgctcgac
gagcgcgcattgttcttgggccagtggggattacgcggaacacgtggtggtcccaatagt
gaaggcccgtcgtacgaagacctcgtcgagaccgaagggcggccgcggctgcgctactgg
ctggatcggttgtccaccgacggcatcctggcgcacgccgccgtggtctacggttacttc
ccggccgtgtccgagggcgacgatgtcgtggtgctcaccgagccagcgcccgacgccgag
gaacggtaccgcttccggttcccacgccagcagcgcggccggttcttgtgcatcgccgat
ttcgtccggtcgcgggagctggctcggcagcggggtgaggtggatgtgctgcctttccag
ctggtgaccatgggtaagccgatcgccgacttcgccaacgagttgttcgcggccaactcc
taccgcgactatctcgaagtgcacggtatcggtgtgcagctcaccgaagcactggccgag
tactggcaccggcgtatccgagaggagctcaggtattcggccgaccgcactatggccgcc
gaggaccccgacgccgtcgaggactacttcaagctgggttaccggggtgcccggttcgcc
ttcggttacggggcatgcccggacctcgaggaccgcgccaaaatgatggagctgctggag
cccgaccgcatcggagtgacgttgtccgaggagttgcagctgcatcccgagcagtcgacc
gacgcgttcgtcctgcaccatcccgaggccaagtacttcaacgtatga
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