KEGG   Mycobacterium ostraviense: LTS72_08835
Entry
LTS72_08835       CDS       T07946                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mot  Mycobacterium ostraviense
Pathway
mot00270  Cysteine and methionine metabolism
mot00450  Selenocompound metabolism
mot00670  One carbon pool by folate
mot01100  Metabolic pathways
mot01110  Biosynthesis of secondary metabolites
mot01230  Biosynthesis of amino acids
mot04980  Cobalamin transport and metabolism
mot04981  Folate transport and metabolism
Module
mot_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:mot00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    LTS72_08835 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    LTS72_08835 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    LTS72_08835 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    LTS72_08835 (metH)
   04980 Cobalamin transport and metabolism
    LTS72_08835 (metH)
Enzymes [BR:mot01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     LTS72_08835 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding V_ATPase_I_N
Other DBs
NCBI-ProteinID: UGT93361
LinkDB
Position
1952562..1956149
AA seq 1195 aa
MTAANKPSYDTDLLDVLVRRVVVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVL
ESIHRNYFEVGADAVETNTFGCNLSNLGDYDIADKIRDLSEKGTAIARRVADEMGTAERR
RYVLGSMGPGTKLPTLGHTEYAVIRDAYTEAALGMLDGGADAILVETCQDLLQLKAAVLG
SRRAMKQAGRHIPVIAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSE
HLRYLSRHARIPVSVMPNAGLPVLGAKGAEYPLRPDELAEALSGFIAEFGLSLVGGCCGT
TPAHIREVAAAVADVTRPERQVSYEPSVSSLYSAVPFAQDASVLVIGERTNANGSKGFRE
AMIAEDYQRCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALASRLATSSTLPIMLDST
ETPVLQAGLEHLGGRCAINSVNYEDGDGLESRFHKTMELVAEHGAAVVALTIDEEGQART
AEKKVEIAERLIDDITGNWGVDESSILIDTLTFTIATGQEESRKDGIETIEAIRELKRRH
PKVQTTLGLSNISFGLNPAARQVLNSVFLHECQDAGLDSAIVHASKILPMNRIPDEQRKV
ALDLVYDRRRDGYDPLQELMRLFEGVSAASSKESRAAELAKLPLFERLAQRIVDGERNGL
EADLEEAMTQKPPLEIINENLLAGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHM
EKSEDDTGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILEVAEDKS
ADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEIYEGEVH
YARDAFEGLKLMDTIMSAKRGEAPDDDSPEAVKAREKEAERKARHERSKRIAAQRKAAEK
PVEVPDRSDVAADVEVPAPPFWGSRIVKGLAVADYTGMLDERALFLGQWGLRGTRGGPNS
EGPSYEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGDDVVVLTEPAPDAE
ERYRFRFPRQQRGRFLCIADFVRSRELARQRGEVDVLPFQLVTMGKPIADFANELFAANS
YRDYLEVHGIGVQLTEALAEYWHRRIREELRYSADRTMAAEDPDAVEDYFKLGYRGARFA
FGYGACPDLEDRAKMMELLEPDRIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV
NT seq 3588 nt   +upstreamnt  +downstreamnt
gtgactgccgcgaacaaacccagctacgacactgatctgcttgacgttttggtgcggcgt
gtagtggtgggcgacggcgcgatgggcacccagctgcaggccgccgatctcaccctcgac
gacttccgcggcctggagggctgcaacgagatcctcaacgaaacccgtcctgacgtgctg
gaaagcatccaccgcaactatttcgaagtgggcgcggacgcggtagagaccaacaccttc
ggctgtaacctgtccaacctcggtgactacgacatcgcggacaagatccgcgacctgtcc
gagaagggcaccgcgatcgcccgccgggtggccgacgagatgggcaccgccgagcgcaga
cgctatgtactcgggtcgatgggaccgggcaccaagctgccgaccctgggacacaccgag
tacgccgtcattcgcgacgcctacaccgaggccgccctgggaatgctggacggcggggcc
gacgcgatcctggtggagacctgccaggacctgctgcagctgaaggcggcggtgctcggc
tcgcggcgggcgatgaagcaggccggccgccacattccggtgatcgcccacgtcaccgtg
gaaaccaccggcaccatgctgctgggcagtgagatcggcgcggcgctgaccgcggtcgag
cccctcggtgtggacatgatcggcttgaactgcgcgacgggccccgccgagatgagcgag
cacctgcgctacctgtcccggcacgcccgcatcccggtgtcggtgatgcccaacgccggc
ctgccggtgctgggcgccaagggcgccgagtacccgctgcggcccgacgagctggccgag
gcgctgtccggattcatcgccgagttcgggttgtcgctggtcggcggttgctgcggcacc
acgccggcccacatccgcgaggtggccgccgcggtcgccgacgtcacgcgccccgaacgc
caggtgagctacgagccgtcggtgtcgtcgctgtacagcgcggttccgttcgcgcaggac
gcctcggtgctggtgatcggcgaacgcaccaacgccaacggctccaagggttttcgtgag
gcgatgatcgccgaggactaccagaggtgcctggacatcgccaaggaccagacccgcgac
ggcgcacacctgctggacctgtgtgtcgactacgtcggccgcgacggcgtggccgacatg
aaggccctggcgagccggctggccacgtcgtcgaccctgccgatcatgctggattccacc
gaaaccccggtgctgcaagccggtttggaacacctcggtggccgttgcgcgatcaactcg
gtcaactacgaagacggtgacggactcgagtcgcgcttccacaagaccatggaactcgtc
gccgaacacggcgccgccgtcgtcgcactgaccatcgacgaagagggccaggcccgcacc
gccgagaagaaggtcgagatcgccgagcggctgatcgacgacatcaccggtaactggggc
gtcgacgagtcgtcgattctgatcgacacgctgaccttcaccatcgccaccgggcaggag
gagtcccgcaaagacggcatcgaaaccatcgaggccatccgggaattgaagagacgccac
cctaaggtgcagaccacgctcgggctgtccaacatctcgtttggcctcaatcccgctgcg
cgccaagtgctcaactcggtgttcctgcacgaatgccaggacgccgggctggattcggcg
atcgtgcacgcctcgaagatcctgccgatgaaccggatccccgacgagcaacgcaaggtg
gcgctggatctggtctatgaccgccgccgcgacggctacgacccgctgcaggagctgatg
cgcctcttcgagggggtgtcggcggcgtcgtcgaaggaatcgcgtgccgccgaactcgcc
aagctgccgctgttcgagcggttggcgcaacgcatcgtcgacggcgaacgcaacggccta
gaagccgatctcgaggaggcgatgacgcagaagccgccactggagatcatcaacgagaac
ctgctggccggcatgaagacggtcggtgagctgttcggctcgggccagatgcagctgccg
ttcgtgttgcagtccgccgaggtgatgaagaccgccgtggcgtatctggagccgcacatg
gagaaatccgaggacgacacgggtaagggccggatcgtgctggccaccgtcaagggcgac
gtccacgacatcggcaagaacctggtcgacatcatcttgagcaacaacggctacgaggtg
gtcaacatcggcatcaagcagcccatcgccaccattctcgaggtcgccgaggacaagagc
gccgacgtggtgggaatgtcgggcctgctggtgaaatcgactgtggtgatgaaggaaaac
ctcgaggagatgaatacccggggggtcgccgaaaaattcccggtgttgctcggcggcgcg
gcgttgacccgcagctatgtcgaaaacgatctcgccgagatttatgaaggcgaagtgcac
tatgcgcgtgacgctttcgagggcctcaagctcatggacaccatcatgagtgctaagcgg
ggggaggcgccggacgacgacagccccgaagcggtcaaggcccgcgagaaggaagccgag
cgcaaggcccgtcatgagcgctccaaacgcattgcggcgcaacgtaaagccgctgaaaag
ccggtcgaggttcccgaccgttccgacgtcgcggctgatgtcgaggtgcccgccccgccg
ttctggggttcgcggatcgtcaagggcctggccgtcgccgactacacgggtatgctcgac
gagcgcgcattgttcttgggccagtggggattacgcggaacacgtggtggtcccaatagt
gaaggcccgtcgtacgaagacctcgtcgagaccgaagggcggccgcggctgcgctactgg
ctggatcggttgtccaccgacggcatcctggcgcacgccgccgtggtctacggttacttc
ccggccgtgtccgagggcgacgatgtcgtggtgctcaccgagccagcgcccgacgccgag
gaacggtaccgcttccggttcccacgccagcagcgcggccggttcttgtgcatcgccgat
ttcgtccggtcgcgggagctggctcggcagcggggtgaggtggatgtgctgcctttccag
ctggtgaccatgggtaagccgatcgccgacttcgccaacgagttgttcgcggccaactcc
taccgcgactatctcgaagtgcacggtatcggtgtgcagctcaccgaagcactggccgag
tactggcaccggcgtatccgagaggagctcaggtattcggccgaccgcactatggccgcc
gaggaccccgacgccgtcgaggactacttcaagctgggttaccggggtgcccggttcgcc
ttcggttacggggcatgcccggacctcgaggaccgcgccaaaatgatggagctgctggag
cccgaccgcatcggagtgacgttgtccgaggagttgcagctgcatcccgagcagtcgacc
gacgcgttcgtcctgcaccatcccgaggccaagtacttcaacgtatga

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