KEGG   Mycobacterium avium subsp. paratuberculosis K-10: MAP_1859c
Entry
MAP_1859c         CDS       T00156                                 
Symbol
metH
Name
(GenBank) MetH
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mpa  Mycobacterium avium subsp. paratuberculosis K-10
Pathway
mpa00270  Cysteine and methionine metabolism
mpa00450  Selenocompound metabolism
mpa00670  One carbon pool by folate
mpa01100  Metabolic pathways
mpa01110  Biosynthesis of secondary metabolites
mpa01230  Biosynthesis of amino acids
mpa04980  Cobalamin transport and metabolism
mpa04981  Folate transport and metabolism
Module
mpa_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:mpa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    MAP_1859c (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    MAP_1859c (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    MAP_1859c (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    MAP_1859c (metH)
   04980 Cobalamin transport and metabolism
    MAP_1859c (metH)
Enzymes [BR:mpa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     MAP_1859c (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding CdhD
Other DBs
NCBI-ProteinID: AAS04176
UniProt: Q73YU6
LinkDB
Position
complement(2037740..2041528)
AA seq 1262 aa
MEGVHVTAPVTTPASDSFAPNIRPDCTDELTAALRQRIMVIDGAMGTAIQRDRPDEAGYR
GERFKDWPSDLVGNNDLLNLTQPQIIEGIHREYLEAGADILETNTFNANAISLSDYGMEE
LSYELNYAGAALARKAADEFSTPDKPRYVAGALGPTSRTASISPDVNDPGARNVTYDELV
AAYLEAANGLVDGGVDLLIVETIFDTLNAKAAVFALETLFEQRGRRWPVIISGTITDASG
RTLSGQVTEAFWNSIRHAKPIAVGLNCALGAPEMRPYIAEVSRIADTFVSCYPNAGLPNA
FGEYDESPERQASYIADFTEAGLVNLVGGCCGTAPPHIAEIAKVVEGKPPREVPQIPVAT
RLSGLEPLNITDDSLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDI
NMDEGMIDGVAAMDRFTRLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIVNSISLK
EGEEKFVREARLCRKYGAAVVVMAFDEQGQADNLERRKQICARAYRVLTEEVGFPPEDII
FDPNCFALATGIEEHATYGIDFIEACAWIKENLPGVHLSGGISNVSFSFRGNNPVREAIH
SVFLFHAIKAGLDMGIVNAGALVPYDSIDPELRDRIEDVVLNRREDAAERLLEIAERFNK
SADASEDSAAAEWRGLPVRERITHALVKGIDAHVDEDTEELRAEIAAAGGRPIEVIEGPL
MDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPFIEAEKEESGVSGSKDTNGTIVM
ATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPAQKILDAAKEHDADIIGLSGLITPSL
DEMSNFAAEMEREGLQIPLLIGGATTSRAHTAVKISPRRSGPVVWVKDASRSVPVAAALL
DDKQRPALLEATEKDYASLRERHAQKNERPMVTLEKARANRTPIDWDGYTPPVPAIGAGI
REFQDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYDDAQEMLDTLIEE
KWLTPNAVIGFFPANAIGPGFEDIELYTDDTRTEVLTTLHNLRQQGEHRDGIPNRSLGDF
IAPKETGHRDYIGAFAVTAGLGSQEKIAEFKAALDDYSAILLESIADRLAEAFAERMHQR
VRKEFWGYQPDEQLDNDALIDEKYRGIRPAPGYPACPEHTEKVTLWKLMDVKERTGIELT
ESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYAKRKGWTLAEAERWLAPNLGYNP
ED
NT seq 3789 nt   +upstreamnt  +downstreamnt
atggaaggagtgcacgtgaccgcccccgtgaccaccccggcgtcggacagcttcgcgccg
aacatccgccccgactgcaccgacgaactgacggcggcgctgcgccagcggatcatggtg
atcgacggcgccatgggcaccgcgatccagcgggaccgccccgacgaggccggctaccgc
ggcgagcggttcaaggactggccgagcgatctggtcggcaacaacgacctgctcaacctg
acgcagccgcagatcatcgagggcattcaccgcgagtacctcgaggcgggcgccgacatc
ctcgagaccaacaccttcaacgcgaacgcgatctcgctgtccgactacggcatggaggag
ctgagctacgaactgaactacgccggcgccgccctggcccgtaaggccgccgacgagttc
agcaccccggacaagccccgctacgtcgccggggcgctggggccgacgtcgcggaccgcg
tcgatctcgccggacgtcaacgatcccggggcccgcaacgtcacctacgacgagctggtc
gccgcctacctcgaggcggccaacggcctggtcgacggcggtgtcgacctcctgatcgtc
gagacgatcttcgacacgctgaacgccaaggccgcggtgttcgccctcgagacgctgttc
gaacagcgcgggcgccgctggccggtcatcatctcgggcaccatcaccgatgcctccggc
cgaacgctgtccgggcaggtcaccgaggcgttctggaactcgatccggcacgccaagccg
atcgcggtcgggctcaactgcgccctgggcgcgccggagatgcggccctacatcgccgag
gtgtcgcgcatcgcggacaccttcgtctcctgctacccgaacgccggcctgcccaacgcc
ttcggcgagtacgacgagtccccggagcgtcaggcctcctacatcgccgacttcaccgag
gccggcctggtcaacctggtcggcggctgctgcggaaccgcgccgccgcacatcgccgag
atcgccaaggtcgtcgagggtaagccgccgcgcgaggtgccgcagattccggtggccacc
cggctctcgggccttgagccgctcaacatcaccgacgactcgctgttcgtgaacatcggc
gagcgcaccaacatcaccggctcggcccggttccgcaacctgatcaaggccgaggactac
gacaccgcgctgtcggtcgccctgcagcaggtggaggtcggtgcccaggtcatcgacatc
aacatggacgagggcatgatcgacggcgtcgccgcgatggaccggttcaccaggctgatc
gccgccgagccggacatcagccgggtcccggtgatgatcgactcctccaagtgggaggtc
atcgaggccggcctgaagaacgtgcagggcaagccgatcgtcaactcgatctctttgaag
gagggcgaggagaagttcgtccgcgaggcgcggctgtgccgcaagtacggcgccgcggtc
gtcgtgatggccttcgacgaacagggtcaggccgacaacctggagcgccgcaaacagatc
tgcgcacgcgcctaccgcgtgctgaccgaagaggtcggcttcccgcccgaggacatcatc
ttcgacccgaactgcttcgcgctggcgaccggcatcgaggagcacgcgacctacggcatc
gacttcatcgaggcctgcgcctggatcaaggagaacctgccgggggtgcacctctccggc
ggcatctcgaacgtgtcgttctcgttccggggaaacaaccccgtccgcgaggcgatccac
tcggtgttcctgttccacgccatcaaggccggcctggacatgggcatcgtcaacgccggg
gcgctggtgccctacgactcgatcgaccccgagctgcgggaccgcatcgaggacgtcgtg
ctgaaccgccgcgaggacgcggccgaacggctgctggagatcgccgagcggttcaacaag
tccgcagatgcttcggaggattcggcggcggccgagtggcgcggcctgccggtccgcgag
cggatcacgcacgccttggtgaagggcatcgacgcccacgtcgacgaggacaccgaggag
ttgcgggccgagattgccgccgcgggagggcggccgatcgaggtgatcgagggcccgttg
atggacggcatgaacgtcgtcggtgacctgttcggctcgggcaagatgtttttgccccag
gtggtcaagtcggcccgggtgatgaagaaggccgtcgcctacctgctgccgttcatcgag
gcggagaaggaagagtccggcgtgtccggttccaaggacaccaacggcaccatcgtgatg
gcgaccgtcaagggcgacgtccacgacatcggcaagaacatcgtcggggttgtcttgcag
tgcaacaacttcgaggtgatcgacctcggtgtgatggtgccggcccagaagatcctcgat
gctgcgaaggagcacgacgccgacatcatcgggctgtccggcctgatcaccccgtcgctg
gacgagatgtccaacttcgccgccgagatggaacgcgagggcctgcagatcccgctgctg
atcggcggcgcgaccacctcgcgcgcccacacggccgtgaagatctcgccgcgccgttcc
ggcccggtggtctgggtcaaggacgcctcccgctcggtgccggtcgccgccgcgctgctg
gacgacaagcagcgtccggcgctgctggaggccaccgagaaggactacgcgtcgctgcgg
gaacggcacgcccagaagaacgagcggccgatggtgacgctggagaaggcccgcgccaac
cggacgccgatcgactgggacggctacacgccgccggtgcccgcgatcggtgcgggaata
cgggaatttcaggactacgacctcgccgagctgcgcgagtacatcgactggcagccgttc
ttcaacgcctgggagatgaagggccgcttccccgacatcctcaacaacccggccaccggc
gaggcggcccgcaagctctacgacgatgcccaggagatgctcgacaccctgatcgaggag
aagtggctgacgcccaacgcggtgatcgggttcttcccggcgaacgcgatcggcccgggt
ttcgaagacatcgagctgtacaccgacgacacccgcaccgaggtgctgaccacgctgcac
aacctgcgccagcagggtgagcaccgcgacggaatcccgaaccggtcgctgggcgacttc
atcgcccccaaagaaacggggcaccgggactacatcggcgccttcgcggtgaccgcgggg
ctgggcagccaggagaagatcgcggagttcaaggcggccctggacgactacagcgcgatc
ctgctggagtcgatcgccgaccggctggcggaggcgttcgccgaacggatgcaccagcgg
gtccgcaaggagttctggggctaccagcccgacgagcaactggacaacgacgcactcatc
gacgagaagtaccggggaatccggcccgcgccgggctacccggcctgcccggagcacacc
gagaaggtgacgttgtggaagttgatggacgtcaaggagcgcaccggcatcgagctgacg
gagtcgatggccatgtggcccggcgccgccgtcagcggttggtatttctcgcatccgcag
tcgcagtacttcgtggtcgggcggttggcccaggaccaggtcgccgactacgcgaagcgc
aagggctggacgctggccgaggccgagcgctggctggcccccaacctcggctacaacccc
gaggactga

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