Mycolicibacterium pallens: K0O64_22545
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Entry
K0O64_22545 CDS
T07675
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mpae
Mycolicibacterium pallens
Pathway
mpae00020
Citrate cycle (TCA cycle)
mpae00630
Glyoxylate and dicarboxylate metabolism
mpae00785
Lipoic acid metabolism
mpae01100
Metabolic pathways
mpae01110
Biosynthesis of secondary metabolites
mpae01120
Microbial metabolism in diverse environments
mpae01200
Carbon metabolism
mpae01210
2-Oxocarboxylic acid metabolism
Module
mpae_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mpae_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mpae00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
K0O64_22545
00630 Glyoxylate and dicarboxylate metabolism
K0O64_22545
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
K0O64_22545
Enzymes [BR:
mpae01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
K0O64_22545
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
K0O64_22545
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
K0O64_22545
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
K0O64_22545
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Vert_IL3-reg_TF
Motif
Other DBs
NCBI-ProteinID:
QYL15822
UniProt:
A0ABX8VE81
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All DBs
Position
4642702..4646451
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AA seq
1249 aa
AA seq
DB search
MSSTSSPFGQNEWLVEEMYRKFREDPSSVDSSWHEFLVDYNPEPTSDSTAGGNGQPAAKT
AAPVSPPEPAPAPPPAKSAPAKSAPAGNGASSSAAPVKDTAKPPAKEPAPKAAAASSSSS
DGGDETQVLRGAAAAVVRNMNTSLEIPTATSVRAIPAKLMIDNRIVVNNHLKRTRGGKVS
FTHLLGYAIVQAVKKFPNMNRHYAEIDGKPNAVTPAHTNLGLAIDLQGKDGKRSLVVAAI
KNCETMRFGQFIAAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMSGQGA
IVGAGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHELLLSD
DFFDEIFFELGIPYEPVRWRTDNPDSIVDKNARVIELIAAYRNRGHLMADIDPLRLDKTR
FRSHPDLDVNTHGLTLWDLDRVFKVDGFAGKEFKKLRDVLGLLRDAYCRHIGVEYTHILE
PEQQKWLQERIEVKHEGPTVAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAETVIP
MMDAAIDQAAEHALDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDV
KYHLGASGNYIQMFGDNDIEVSLTANPSHLEAVDPVMEGIVRAKQDLLDKGDGDDGFTVM
PLMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHIIVNNQIGFTTSPQDSRSSEYCTDV
AKMVGAPIFHVNGDDPEACVWVARLAVDFRQKFKKDVIIDMLCYRRRGHNEGDDPSMTQP
YMYDVIDTKRGVRKTYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRDLEKHEVEPS
ESVEEDQMIPRGMTTAVDKSLLARIGDAHLAFPENFNVHPRVKPVLEKRREMAYEGKVDW
AFAELLALGTFLAEGKLIRLSGQDTRRGTFTQRHSVIIDRKTGAEFTPLDLLTVNPDGTP
TGGKLMVYDSALSEYAAVGFEYGYSVGNQDALVMWEAQFGDFVNGAQSIIDEFISSGEAK
WGQLSDVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIALPSTPANYFHLLRRHGLD
GVHRPLIVFTPKSMLRNKAAVSDIRDFTEQKFRSIMEEPTYTDGDGDRNKVTRILLTSGK
IYYELAARKDKDKREDVAIVRVEQLAPLPKRRLSNTLDSYPNAKEFFWVQEEPANQGAWP
TFGLTLPELLPEKLTGIKRISRRAMSAPSSGSSKVHVVEQQEIIDEAFG
NT seq
3750 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagtactagttcaccattcggacagaacgaatggctggtcgaggagatgtaccgc
aagttccgcgaggacccctcctcggtcgactcgagttggcatgagttccttgtcgactac
aacccggagccgacgagcgactcgaccgccggtggtaacggccaaccggccgcgaagacc
gccgctccggtgtcaccaccggaacccgcaccggcccccccgccggccaagtccgctccc
gccaagtccgctcccgcgggcaatggcgcgtcgagctcggccgctccggtcaaagacacc
gccaagcctccggccaaggagccggcacccaaggccgcagcagcgtcgtcgtcgtcgtcc
gatggcggcgacgagacgcaggtgttgcgcggcgcggcagcagccgtcgtccgcaacatg
aacacctcgctggagatcccgaccgcgaccagtgtgcgggccatcccggcgaagctgatg
atcgacaaccgcatcgtcgtcaacaaccacctcaagcgcactcgcggcggcaaggtgtcc
ttcacccacctgctcggctacgcgatcgtgcaggcggtcaagaagttcccgaacatgaac
cggcactacgccgagatcgacggcaagcccaacgccgtcacgcccgcgcacaccaatctg
ggcctcgcgatcgacctgcaaggcaaggacggtaagcgctcgctggtggtcgccgcgatc
aagaactgcgagaccatgcggttcggccagttcatcgccgcctacgaggacatcgtgcgg
cgcgcccgcgacggcaagctcaccgccgaggatttcgccggtgtgacgatctcgctgacc
aaccccggcaccatcggcaccgtgcactcggtgccccggttgatgtccggccagggtgcg
atcgtcggcgccggcgcgatggagtacccggcggagttccagggcgcgagcgaggagcgc
atcgccgaactgggcatcggcaagctcatcacgctgacgtcgacctacgaccaccgcatc
attcagggtgcggagtccggcgacttcctgcggaccatccacgaactgctgctgtcggac
gatttcttcgacgagatcttcttcgagctgggcatcccttacgagccggtccgctggcgc
accgacaaccccgattcgatcgtcgacaagaacgctcgcgtcatcgaactcattgcggcc
taccgcaaccgcgggcatctgatggccgacatcgacccgctgcgcttggacaagacccgc
ttccgcagccaccccgacctcgacgtcaacacccacggcttgacgctgtgggatctcgac
cgggtgttcaaggtcgacgggttcgcgggcaaggagttcaagaagctgcgcgacgtgctc
gggctgctgcgcgacgcctactgccgccacatcggtgtggagtacacccacatcttggag
cccgagcagcagaagtggctgcaggagcgcatcgaggtcaagcacgaaggtccgacggtc
gcccagcagaagtacatcctgtcgaagctgaacgccgctgaggccttcgagaccttcctg
cagacgaaatacgttgggcagaagcgcttctcgctggagggtgcggaaaccgtcatcccg
atgatggacgccgcgatcgaccaggccgccgagcacgccctcgacgaggtcgtgatcggc
atgccgcaccgcggccggctcaacgtgctggccaacatcgtcggcaagccctactcgcag
atcttcagcgagttcgagggcaacctgaacccgtcgcaggcgcacggttccggtgacgtc
aagtaccacctcggcgccagcggcaactacatccagatgttcggcgacaacgacatcgag
gtctcgctgaccgccaacccgtcgcacctggaagccgtggacccggtgatggaaggcatc
gttcgggccaagcaggacctgctcgacaagggcgacggcgacgacggcttcaccgtcatg
ccgctgatgctgcacggcgatgcggccttcgccggtcagggcgtggtggccgagaccctc
aaccttgcgctgctgcgcggctaccgcactggcggcacgatccacatcatcgtcaacaac
cagatcggcttcactacctcgccgcaggactcacgcagctcggagtactgcaccgacgtc
gcaaagatggtgggagcgcccatcttccacgtcaacggtgacgatccggaggcctgcgtc
tgggtggcgcggctggcggtggacttcaggcagaagttcaagaaggacgtcatcatcgac
atgctgtgctaccgccgccgcgggcacaacgagggtgacgacccgtcgatgacccagccg
tacatgtacgacgtcatcgacaccaagcgcggtgtccgcaagacctacaccgaagccctg
atcggccgcggcgacatctcgatgaaagaggccgaggacgcgctgcgcgactaccagggt
cagctggagcgagtgttcaacgaggtccgcgatctcgagaaacacgaggtcgaaccgagc
gaatcggtcgaagaagaccagatgatcccgcgcggcatgaccaccgcggtggacaagtcg
ctgctggcccgtatcggtgacgcgcatctggcgttcccggagaacttcaacgtgcacccc
cgcgtcaagccggtgctggagaagcgccgcgagatggcgtacgagggcaaggtcgactgg
gcgttcgccgaattgctcgcgctcggaacatttttggccgaaggcaagctgatccgcttg
tcgggtcaggacactcggcgcggcacgttcacccagcggcactcggtgatcatcgaccgc
aagaccggcgcggagttcaccccgctggacctgctgaccgtcaacccggacggcacaccg
accggcggcaagctgatggtgtacgactcggcgctgtcggagtacgcggcggtcggcttc
gaatacggctattccgtgggcaatcaggacgcactcgtcatgtgggaggcgcagttcggc
gatttcgtcaacggtgcgcagtcgatcatcgacgagttcatcagttccggcgaggccaag
tggggtcagctctccgatgtggtgctgctgctcccccacggccatgagggccaaggcccc
gaccacacctcgggtcgcatcgagcggttcctccagctgtgggccgagggttcgatgacg
atcgcgctgccgtcgaccccggcgaactacttccatctgttgcgccggcacggcctcgac
ggagtgcaccgtccgctgatcgtgttcacgccgaagtcgatgctgcgcaacaaggctgcc
gtcagcgacatccgggacttcaccgagcagaagttccggtcgatcatggaggagccgacc
tacaccgacggcgacggcgaccgcaacaaggtcacccgaatcctgttgaccagcggcaag
atctactacgagctggcggcgcgcaaggacaaggacaagcgcgaggacgtcgcgatcgtc
cgcgtcgagcagctggcgccgctgcccaagcggcgactgagcaacaccttggattcctac
ccgaatgccaaggagttcttctgggttcaagaggagccggccaaccagggtgcgtggccg
acgttcggcttgacgctgccggagttgttgccggagaagctgaccgggatcaagcggatc
tcgcggcgcgcgatgtcggcgccgtcgtccggctcgtcgaaggtgcacgtcgtcgagcag
caggagatcatcgacgaggcgttcggctag
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