Mycolicibacterium phlei: MPHLCCUG_03388
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Entry
MPHLCCUG_03388 CDS
T04305
Symbol
aceE_1
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mphl
Mycolicibacterium phlei
Pathway
mphl00010
Glycolysis / Gluconeogenesis
mphl00020
Citrate cycle (TCA cycle)
mphl00620
Pyruvate metabolism
mphl00785
Lipoic acid metabolism
mphl01100
Metabolic pathways
mphl01110
Biosynthesis of secondary metabolites
mphl01120
Microbial metabolism in diverse environments
mphl01200
Carbon metabolism
mphl01210
2-Oxocarboxylic acid metabolism
Module
mphl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mphl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MPHLCCUG_03388 (aceE_1)
00020 Citrate cycle (TCA cycle)
MPHLCCUG_03388 (aceE_1)
00620 Pyruvate metabolism
MPHLCCUG_03388 (aceE_1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MPHLCCUG_03388 (aceE_1)
Enzymes [BR:
mphl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MPHLCCUG_03388 (aceE_1)
BRITE hierarchy
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AMO62191
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All DBs
Position
3437845..3440727
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AA seq
960 aa
AA seq
DB search
MDKDEIRRFTRAGRKHLHRPGEPEKPHNKERKLTTEFARQDLAQNSTTAAEHDRVRVIRE
GVASYLPDIDPEETSEWLESFDALLARSGPARARYLMLRMLERAGEQRVAIPSLTSTDYV
NTIPTEKEPWFPGDEEVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVG
FNHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHPGGGLPSYP
HPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTSDQHVWAFLGDGEMDEPES
RGLAHVAALEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVIWGREW
DALLHADRDGALVNLMNSTPDGDYQTYKANDGAYVREHFFGRDPRTKALVQNMTDEQIWN
LKRGGHDYRKVYAAYKAAVEHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALEDLK
FFRDAQRIPISDKQLEENPYLPPYYHPGPEAPEIRYMVERRRALGGFLPERRTKSKVLAL
PSREVYKPLKKGSGKQEVATTMAIVRTFKELLRDKNIGHRIVPIIPDEARTFGMDSWFPS
LKIYNRNGQLYTSVDADLMLAYKESEAGQILHEGINEAGSTASFTAVGTSYATHNEPMIP
VYIFYSMFGFQRTGDGFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSHLLASTNPA
VVAYDPAFAYEIAYIVESGLHRMYGENAENVFFYITVYNEPYVQPAEPEGIDVDGLLRGI
YRYQAAEPKANAAQILASGVAMPEALRAAELLAAEWDVAADVWSVTSWTELNRDGVAIEK
QRLRHPDQPAGTPYVTQALADAPGPVIAVSDWMRAVPEQIRPWVPGTYITLGTDGFGFSD
TRPAARRYFNTDAESIVVAVLEGLARDGNIDASVAVEAAKRYEIDDVMAAPEQTSDSGVA
NT seq
2883 nt
NT seq
+upstream
nt +downstream
nt
ttggacaaggatgaaatccgccgtttcacccgtgcgggcagaaaacatctgcaccggccc
ggggagcccgaaaaaccgcataacaaggagcggaagttgacgaccgagttcgcgcgccag
gacctggcccaaaactccaccaccgcagccgaacacgaccgagtgcgagtcatccgcgaa
ggggtcgcgtcgtacctgcccgacatcgaccccgaagagaccagcgaatggttggagtcg
ttcgacgcgctgctggcgcgatcggggcccgcccgggcccgctacctgatgctccggatg
ctggaacgggccggcgagcagcgggtcgccatcccctcgctgacgtcgacggactacgtc
aacaccatccccaccgagaaggaaccctggttccccggtgacgaggaggtcgagcgccgc
taccgcgcctggatccgctggaacgcggcgatcatggtgcaccgcgcgcagcgacccgga
gtcggtgtgggcggccatatttcgacttatgcctcgtcggcggcgctgtacgaggtcggg
ttcaaccacttcttccgcggcaagtcccaccccggcggcggcgaccaggtgttcatccag
ggccacgcctcccccggcatctacgcccgcgcgttcctggagggccggctcaccgccgaa
cagctcgacgggttccgccaggagcacagccacccgggcggcgggctgccgtcctacccg
cacccgcggctgatgcccgacttctgggagttcccgacggtgtcgatgggcctgggcccg
atgaacgcgatctaccaggcccggttcaaccactacctgcacgaccgcggcatcaaggac
acctccgaccagcacgtgtgggcgttcctcggcgacggtgagatggacgagccggagagc
cgcgggctggcgcacgtcgccgcgctggagggcctggacaacctgaccttcgtcgtcaac
tgcaacctgcagcgcctcgacggcccggtgcgcggcaacggcaagatcatccaggagctg
gagtcgttcttccgcggcgccggctggaacgtcatcaaggtgatctggggccgcgagtgg
gacgcgctgctgcacgccgaccgcgacggcgcgctggtcaacctgatgaactccacaccc
gacggcgactaccagacctacaaggccaacgacggcgcctacgtgcgcgagcacttcttc
ggccgcgacccgcgcaccaaggcgctggtccagaacatgaccgacgagcagatctggaac
ctcaagcgcggcggccacgactaccgcaaggtctacgccgcctacaaggccgccgtcgaa
cacaagggccagcccacggtgatcctggccaagacgatcaagggctactcgctgggtgcg
cacttccagggccgcaacgccacccaccagatgaagaagctcgcgctggaggacctcaag
ttcttccgcgacgcgcagcggatcccgatcagcgacaagcagctcgaggagaacccgtac
ctgccgccgtactaccacccgggcccggaggcgccggagatccggtacatggtcgagcgt
cggcgcgcgctgggcggcttccttccggagcggcgcaccaagtccaaggtgctggccctg
ccgagccgcgaggtctacaagccgctgaagaagggttccggcaagcaggaggtggccacc
acgatggccatcgtccgcacgttcaaggaactgttgcgcgacaagaacatcggccaccgg
atcgtgccgatcatccccgacgaggcccgcacgttcggcatggactcgtggttcccgtcg
ctgaagatctacaaccgcaacggccagctgtacacctcggtcgacgccgatctgatgttg
gcgtacaaggagtccgaggccggccagatcctgcacgagggcatcaacgaggccgggtcg
acggcgtcgttcaccgcggtcggcacctcgtacgccacccacaacgagccgatgatcccg
gtctacatcttctattcgatgttcgggttccagcgcaccggcgacgggttctgggcggcg
gccgaccagatggcgcgcggcttcgtgctgggtgcgacggccgggcgcaccacgctgacc
ggtgagggtctgcagcacgccgacgggcactcccatctgttggcgtcgacgaatcccgct
gtggtggcctacgatccggcgttcgcctacgagatcgcctacatcgtcgagagcggtctg
caccgcatgtacggcgagaacgccgagaacgtcttcttctacatcacggtgtacaacgag
ccgtacgtgcagccggccgagcccgagggcatcgacgtcgacggtctgttgcgcggcatc
taccgctaccaggcggccgaaccgaaggccaacgccgcgcagatcctggcctcaggcgtg
gcgatgcccgaggcgctgcgggccgccgagctgctggccgccgagtgggatgtggccgcc
gacgtgtggtcggtgaccagctggaccgagctcaaccgcgacggtgtggcgatcgagaag
cagcggctgcgccaccccgaccagccggcgggcaccccgtacgtcactcaggcgctcgcc
gacgcacccggcccggtgatcgcggtgtcggactggatgcgcgcggtccccgagcagatc
cgtccgtgggtgccgggcacctacatcacgctgggcaccgacgggttcgggttctccgac
acccggcccgcggcgcgccggtacttcaataccgacgccgagtcgatcgtggtcgcggtg
ctggagggtctggcccgcgacggcaacatcgacgcgtcggtggcggtcgaggcggccaag
cgctacgagatcgacgacgtgatggcggcccccgagcagacgtcggattcgggcgtcgcc
tag
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