Mycolicibacterium phocaicum: MPHO_24110
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Entry
MPHO_24110 CDS
T07283
Symbol
kgd
Name
(GenBank) multifunctional 2-oxoglutarate metabolism enzyme
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mphu
Mycolicibacterium phocaicum
Pathway
mphu00020
Citrate cycle (TCA cycle)
mphu00630
Glyoxylate and dicarboxylate metabolism
mphu00785
Lipoic acid metabolism
mphu01100
Metabolic pathways
mphu01110
Biosynthesis of secondary metabolites
mphu01120
Microbial metabolism in diverse environments
mphu01200
Carbon metabolism
mphu01210
2-Oxocarboxylic acid metabolism
Module
mphu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mphu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mphu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
MPHO_24110 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
MPHO_24110 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MPHO_24110 (kgd)
Enzymes [BR:
mphu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
MPHO_24110 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
MPHO_24110 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
MPHO_24110 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
MPHO_24110 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
DEC-1_N
Motif
Other DBs
NCBI-ProteinID:
BBZ55419
UniProt:
A0A7I7ZNX3
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All DBs
Position
2511506..2515180
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AA seq
1224 aa
AA seq
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MSTSPSPFGQNEWLVEEMYRKFREDPSSVDPSWHDFLRDYNPEPITDTTDSVAAAAPAPA
AAPAPAAAPAPTAAPAKAAPAKAAAGPAPAEDAETQTLRGAAAAVVKNMNASLDVPTATS
VRAIPAKLMIDNRVVINNHLKRTRGGKISFTHLLGYAIVQAVKQFPNMNRYFAEVDGKPT
AVTPAHTNLGLAIDLQNKDGSRQLVVAAIKRCETMQFGQFIAAYEDIVRRARDGKLTAED
FSGVTISLTNPGTIGTVHSVPRLMRGQGAIIGAGAMEYPAEFQGASEERIAELGVGKLIT
LTSTYDHRIIQGAESGDFLRTVHHLLLDDAFFDEIFRELGIPYEPVRWRIDNPDSIAHKN
ARIIELIAAYRNRGHLMADIDPLRLDKTRFRSHPDLDVNTHGLTLWDLDREFKVDGFAGK
QFMKLRDVLSVLRDAYCRHVGVEYTHILEPEQQKWLQERVEVKHDKLAVGEQKYILSKLN
AAEAFETFLHTKYVGQKRFSLEGAEAVIPMMDAAIDQAAEHGLDEVVIGMPHRGRLNVLA
NIVGKPYAKIFSEFEGNLNPALAHGSGDVKYHLGATGHYLQMFGDNEIDVSLVANPSHLE
AVDPVLEGLVRAKQDLLVGDEHDDSDAHGRFSIMPMMLHGDAAFAGQGVVAETLNLALLK
GYRTGGTIHIIVNNQIGFTTAPTDSRSSEYCTDVAKMIGAPIFHVNGDDPEACAWVARIA
VDFREAFKKDVVIDMLCYRRRGHNEGDDPSMTQPYMYDVIDTKRGVRKTYTEALIGRGDI
SIKEAEDALRDYQGQLERVFNEVRELEKHEIEPSESVESDQTIPQRLLTAVDKSLLARIG
DAHLAVPEGFNVHPRVKPVLEKRREMAYEGKVDWAFAELLALGSMVAEGRLIRFSGQDTQ
RGTFTQRHAVLIDRVTGEEFTPLQLLATNTDGTPTGGKLLIYNSALSEFAAVGFEYGYSV
GNPDAMVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDHTSGR
IERFLQVCAEGSMTVAMPSTPANYFHLLRRHGLDGIHRPLIVFTPKSMLRNKAAVSDIKD
FTEIKFRSVLEEPTYEDGVGDRSKVTRVLLTSGKLYYELVARKAKDKRDDIAILRIEQLY
PLPKRRLNATLDQYPNVQQYFWVQEEPANQGAWPTFGLSLPELLPEKLTGIKRISRRAMS
APSSGSSKVHAIEQQAIIDEAFAP
NT seq
3675 nt
NT seq
+upstream
nt +downstream
nt
gtgagcacatcaccttcaccattcggtcagaacgagtggctggtcgaagagatgtatcgc
aaattccgtgaggacccgtcctcggtggacccgagttggcacgacttcctgcgtgactac
aaccccgaacccataacggacacaacggattccgtggccgccgcagccccggcccccgcc
gcggcgcccgcccctgccgcggcgcctgcccccaccgccgcgccggccaaggccgccccc
gccaaggccgccgccggacccgcgcccgccgaggacgccgagacgcagacgctgcgcggc
gccgcggccgccgtcgtcaagaacatgaacgcgtcactggacgtgccgaccgccacgagt
gtgcgcgccatccccgcgaagctgatgatcgacaaccgcgtcgtcatcaataaccacctc
aagcgcacccgcggcggcaagatcagcttcacccacctgctgggctacgcgatcgtccag
gcggtcaagcagttcccgaacatgaaccggtacttcgcggaggtcgacggcaagccgacg
gccgtcacgccggcgcacaccaacctcggtctggccatcgacctgcagaacaaggacggc
tcgcgccaactcgtcgtcgcggccatcaagcgttgcgagacaatgcaattcggccagttc
atcgccgcctacgaggacatcgtccggcgggcccgcgacggcaagctgaccgccgaggac
ttcagcggcgtcaccatctcgctgaccaaccccggcaccatcggcaccgtacactcggtg
ccgcgcctgatgcgcggtcagggcgcgatcatcggcgccggtgccatggagtacccggcc
gagttccaaggcgcgagtgaagagcgcatcgccgagctcggcgtcggcaagctcatcacg
ctgacctcgacctacgaccaccgcatcatccagggcgccgagtccggcgacttcctgcgc
accgtgcaccacctgctgctcgacgacgccttcttcgacgagatcttccgcgagctgggc
atcccctatgagccggtgcgctggcggatcgacaacccggactcgatcgcccacaagaac
gcccgcatcatcgagctgatcgcggcctaccgcaaccgcggtcacctgatggccgacatc
gacccgctgcgcctggacaagacgcgcttccgcagccaccccgacctcgacgtcaacacc
cacggcctgacgctgtgggatctggaccgcgagttcaaggtcgacggcttcgccggcaag
cagttcatgaagctgcgcgacgtgctgtcggtgctgcgtgacgcctactgccgccacgtc
ggtgtcgagtacacccacatcctcgaacccgagcagcagaagtggctgcaggagcgcgtc
gaggtcaagcacgacaagctggccgtcggcgaacagaagtacatcctgtccaagctcaac
gccgccgaggccttcgagaccttcctgcacaccaaatacgttgggcagaagcgcttctca
ctggaaggcgcggaggccgtcatcccgatgatggacgccgccatcgaccaggccgccgag
cacggactcgacgaagtggtcatcggcatgccgcaccgcggtcgcctcaacgtgctggcc
aacatcgtcggcaagccgtacgcgaagatcttcagcgagttcgagggcaacctgaacccg
gcgctggcgcacggctccggcgacgtgaagtaccacctcggtgccaccggccactacctg
cagatgttcggcgacaacgagatcgacgtgtcgctggtggccaaccccagccacctcgaa
gccgtcgaccccgtgctcgagggtctggtccgcgccaagcaggacctgctggtcggcgac
gagcatgacgacagcgacgcgcacggccgcttctcgatcatgccgatgatgctgcacggc
gacgccgcgttcgccggtcagggcgtggtcgccgagacgctcaacctcgcgctgctcaag
ggctaccgcaccggcggcaccatccacatcatcgtgaacaaccagatcgggttcaccacg
gcgccaacggattcgcgctccagcgagtactgcaccgacgtggccaagatgatcggcgcc
ccgatcttccacgtcaacggcgacgaccccgaggcctgcgcctgggtggcgcggatcgcg
gtcgacttccgtgaggcgttcaagaaggacgtcgtcatcgacatgctgtgctaccgccgc
cgcggccacaacgaaggcgatgacccgtcgatgacgcagccgtacatgtacgacgtcatc
gacaccaagcgcggcgtccgcaagacctacaccgaagccctcatcggccgtggtgacatc
tccatcaaagaggccgaggacgccctgcgcgactaccagggccagctggagcgggtcttc
aacgaggtccgtgagctcgagaagcacgagatcgagcccagcgaatcggtggagtccgac
cagaccatcccgcagcgcctgctgaccgcggtcgacaagtcgctgctcgcccgcatcggc
gacgcgcacctggcggtacccgagggcttcaacgtgcacccgcgcgtcaagcccgtgctc
gagaagcgccgcgagatggcctacgaaggcaaggtcgactgggcgttcgccgagctgctg
gccctgggctcgatggtcgccgagggccggttgatccggttctccgggcaggacacccag
cgcggtaccttcacgcaacggcacgcagtcctcatcgaccgcgtcaccggtgaggagttc
accccgctgcagctgctggccaccaacaccgacggcacgcccaccggcggcaagctgctg
atctacaactcggcgctgtccgagttcgcggcggtcggcttcgagtacggctactcggtg
ggcaatcccgacgccatggtgctgtgggaagcccagttcggagacttcgtcaacggcgcg
cagtcgatcatcgacgagttcatcagctccggcgaggccaagtggggccagctctccgac
gtcgtgctgctgctgccgcacggtcacgagggccagggcccggaccacacgtcgggccgc
atcgagcggttcctgcaagtgtgcgccgaaggttcgatgacggtcgccatgccgtcgacc
ccggccaactacttccacctgctgcgccgacacggcctcgacggcatccaccggccactg
atcgtcttcaccccgaagtccatgctgcgcaacaaggcggcggtcagcgacatcaaggac
ttcaccgagatcaagttccgctcggtgctcgaggagccgacctacgaagacggcgtcggc
gaccggtcgaaggtcacccgggtcctactcaccagcggcaagctgtactacgagctggtg
gcccgcaaggccaaggacaagcgcgacgacatcgcgatcctccgcatcgagcagctgtac
ccgctgcccaagcgccggctcaacgccacgttggaccagtacccgaacgtgcagcagtac
ttctgggtacaggaagagccggccaaccagggtgcctggccgacgttcggcctgagcctg
cccgagctgctgccggagaagctgaccggcatcaagcgcatctcgcgccgggccatgagc
gcgccgtcgtcgggttcgtcgaaggtgcacgccatcgagcagcaggccatcatcgacgag
gcgttcgcgccctaa
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