KEGG   Mustela putorius furo (domestic ferret): 101673063
Entry
101673063         CDS       T07239                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X1
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
mpuf  Mustela putorius furo (domestic ferret)
Pathway
mpuf01522  Endocrine resistance
mpuf04110  Cell cycle
mpuf04115  p53 signaling pathway
mpuf04151  PI3K-Akt signaling pathway
mpuf04218  Cellular senescence
mpuf04530  Tight junction
mpuf04660  T cell receptor signaling pathway
mpuf04933  AGE-RAGE signaling pathway in diabetic complications
mpuf04934  Cushing syndrome
mpuf05160  Hepatitis C
mpuf05162  Measles
mpuf05163  Human cytomegalovirus infection
mpuf05164  Influenza A
mpuf05165  Human papillomavirus infection
mpuf05166  Human T-cell leukemia virus 1 infection
mpuf05167  Kaposi sarcoma-associated herpesvirus infection
mpuf05169  Epstein-Barr virus infection
mpuf05200  Pathways in cancer
mpuf05203  Viral carcinogenesis
mpuf05212  Pancreatic cancer
mpuf05214  Glioma
mpuf05218  Melanoma
mpuf05219  Bladder cancer
mpuf05220  Chronic myeloid leukemia
mpuf05222  Small cell lung cancer
mpuf05223  Non-small cell lung cancer
mpuf05224  Breast cancer
mpuf05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:mpuf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    101673063 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    101673063 (CDK4)
   04115 p53 signaling pathway
    101673063 (CDK4)
   04218 Cellular senescence
    101673063 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    101673063 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    101673063 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101673063 (CDK4)
   05203 Viral carcinogenesis
    101673063 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    101673063 (CDK4)
   05225 Hepatocellular carcinoma
    101673063 (CDK4)
   05214 Glioma
    101673063 (CDK4)
   05220 Chronic myeloid leukemia
    101673063 (CDK4)
   05218 Melanoma
    101673063 (CDK4)
   05219 Bladder cancer
    101673063 (CDK4)
   05224 Breast cancer
    101673063 (CDK4)
   05222 Small cell lung cancer
    101673063 (CDK4)
   05223 Non-small cell lung cancer
    101673063 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101673063 (CDK4)
   05160 Hepatitis C
    101673063 (CDK4)
   05164 Influenza A
    101673063 (CDK4)
   05162 Measles
    101673063 (CDK4)
   05163 Human cytomegalovirus infection
    101673063 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101673063 (CDK4)
   05169 Epstein-Barr virus infection
    101673063 (CDK4)
   05165 Human papillomavirus infection
    101673063 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101673063 (CDK4)
   04934 Cushing syndrome
    101673063 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101673063 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mpuf01001]
    101673063 (CDK4)
Enzymes [BR:mpuf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     101673063 (CDK4)
Protein kinases [BR:mpuf01001]
 Serine/threonine kinases: CMGC group
  CDK family
   101673063 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 101673063
NCBI-ProteinID: XP_004773325
Ensembl: ENSMPUG00000002016
UniProt: A0A8U0NAV3
LinkDB
Position
Unknown
AA seq 303 aa
MATPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPEMEESGAQLMLEMLTFNPHKRISAFRALQHSYLQKPEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctactcctcgatatgagccagtggctgagattggtgttggtgcctatggaacggta
tacaaggcccgtgatccccacagtggacacttcgtggccctcaagagcgtgagagtccct
aatggaggaggtgctggagggggccttcccatcagcacagttcgtgaggtggccttactg
aggcggctggaggcttttgagcatcccaacgttgttcggctgatggatgtctgtgccacc
gcccgaactgatcgggagaccaaagtgaccctggtgtttgagcacgtggaccaagacctg
aggacatatctggacaaggcaccccccccgggcttgccagtggagaccatcaaggatctc
atgcgccagtttctaagaggcctagatttccttcatgccaactgcattgttcaccgagac
ctgaagccagagaacattctggtgaccagtggtgggacagtgaagctggctgactttggc
ctggccagaatctacagctaccagatggcacttacacctgtggttgttacactctggtac
cgtgctccagaagttcttctgcagtctacatatgcaacacctgtggacatgtggagcgtt
ggctgtatcttcgcagagatgtttcgtcgcaagcctctcttctgtggaaactctgaagct
gaccagttaggcaaaatctttgacctgatcgggctgcctccagaggatgactggccccga
gatgtatctctaccccgaggagccttttcccccagagggccccgtccggtgcagtcagtg
gtacctgagatggaggagtctggagcacagctaatgctggagatgctgacttttaaccca
cacaagcgaatctctgccttccgagccctgcagcactcttacctacaaaagccagaaggt
aacccagagtga

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