KEGG T07239: 101676725

Mustela putorius furo (domestic ferret): 101676725

Entry

101676725         CDS       T07239

Symbol

DHFR

Name

(RefSeq) dihydrofolate reductase

K00287

dihydrofolate reductase [EC:1.5.1.3]

Organism

mpuf Mustela putorius furo (domestic ferret)

Pathway

mpuf00670

One carbon pool by folate

mpuf00790

Folate biosynthesis

mpuf01100

Metabolic pathways

mpuf01240

Biosynthesis of cofactors

mpuf01523

Antifolate resistance

mpuf04981

Folate transport and metabolism

Brite

KEGG Orthology (KO) [BR:mpuf00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    101676725 (DHFR)
   00670 One carbon pool by folate
    101676725 (DHFR)
09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    101676725 (DHFR)
09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    101676725 (DHFR)
Enzymes [BR:mpuf01000]
1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     101676725 (DHFR)

SSDB

Motif

Pfam:

DHFR_1

Other DBs

NCBI-GeneID:

101676725

NCBI-ProteinID:

XP_004759208

Ensembl:

ENSMPUG00000008704

LinkDB

Position

Unknown

AA seq 227 aa
MVRTLNCIAAVSQNMGIGKNGDLPWPPLRNEFKFFQRMTTTSSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINLVLSRDLKEPPQGAHFLAKSLDDALKLIEQPELANKVDMVWIVGGSS
VYKEAMNKPGHLRLFVTRIMQEFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKALSTNL
KYMRRTINVKETSDGPGSFSVHTLTFLLNLFILGIKKRTNQFVWYFK

NT seq 684 nt +upstreamnt +downstreamnt
atggttcgtacgctaaactgcatcgccgctgtttcccagaacatgggcatcggcaagaac
ggggacctgccctggcccccgctcaggaacgaattcaagtttttccaaagaatgaccaca
acctcctcagtagaaggtaaacagaacttggtgattatgggtagaaagacatggttctct
attcctgagaagaatcgacctttaaaggatagaattaatttagttctcagcagagacctc
aaggaacctccacagggagctcattttcttgccaaaagtttggatgatgccttaaaactt
attgagcaaccagaattagcaaataaagtggacatggtttggatagtgggaggcagttct
gtttataaggaagccatgaacaaaccaggccatcttagactatttgtgacaaggattatg
caggaatttgaaagtgacacattttttccagaaattgatttggagaaatataaacttctg
ccagaatacccaggagttctttctgatgtccaggaggaaaaggcattaagtacaaatttg
aagtatatgagaagaacgattaatgtgaaggagacctcagatggaccaggaagtttttct
gtccatacactgacatttctgttgaatctctttattcttggaataaaaaagagaacaaat
cagtttgtgtggtatttcaaataa

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