Mustela putorius furo (domestic ferret): 101677072 Help Entry 101677072         CDS       T07239                                  Symbol INSR Name (RefSeq) insulin receptor isoform X2   KO K04527   insulin receptor [EC:2.7.10.1] Organism mpuf  Mustela putorius furo (domestic ferret) Pathway mpuf04010   MAPK signaling pathway mpuf04014   Ras signaling pathway mpuf04015   Rap1 signaling pathway mpuf04022   cGMP-PKG signaling pathway mpuf04066   HIF-1 signaling pathway mpuf04068   FoxO signaling pathway mpuf04072   Phospholipase D signaling pathway mpuf04081   Hormone signaling mpuf04150   mTOR signaling pathway mpuf04151   PI3K-Akt signaling pathway mpuf04152   AMPK signaling pathway mpuf04211   Longevity regulating pathway mpuf04213   Longevity regulating pathway - multiple species mpuf04520   Adherens junction mpuf04910   Insulin signaling pathway mpuf04913   Ovarian steroidogenesis mpuf04923   Regulation of lipolysis in adipocytes mpuf04930   Type II diabetes mellitus mpuf04931   Insulin resistance mpuf04932   Non-alcoholic fatty liver disease mpuf04960   Aldosterone-regulated sodium reabsorption mpuf05010   Alzheimer disease mpuf05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:mpuf00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     101677072 (INSR)    04015 Rap1 signaling pathway     101677072 (INSR)    04066 HIF-1 signaling pathway     101677072 (INSR)    04068 FoxO signaling pathway     101677072 (INSR)    04072 Phospholipase D signaling pathway     101677072 (INSR)    04022 cGMP-PKG signaling pathway     101677072 (INSR)    04151 PI3K-Akt signaling pathway     101677072 (INSR)    04152 AMPK signaling pathway     101677072 (INSR)    04150 mTOR signaling pathway     101677072 (INSR)   09133 Signaling molecules and interaction    04081 Hormone signaling     101677072 (INSR)  09150 Organismal Systems   09152 Endocrine system    04923 Regulation of lipolysis in adipocytes     101677072 (INSR)    04913 Ovarian steroidogenesis     101677072 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     101677072 (INSR)   09149 Aging    04211 Longevity regulating pathway     101677072 (INSR)    04213 Longevity regulating pathway - multiple species     101677072 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     101677072 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     101677072 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101677072 (INSR)    04932 Non-alcoholic fatty liver disease     101677072 (INSR)    04931 Insulin resistance     101677072 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mpuf01001]     101677072 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:mpuf04090]     101677072 (INSR) Enzymes [BR:mpuf01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      101677072 (INSR) Protein kinases [BR:mpuf01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    101677072 (INSR) CD molecules [BR:mpuf04090]  Proteins   101677072 (INSR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  101677072 NCBI-ProteinID:  XP_004771790 Ensembl:  ENSMPUG00000008446 LinkDB All DBs Position Unknown AA seq 1363 aa AA seqDB search MACLLTCLAFGLFLLLVCPGMDIRNNLTRLHELANCSVIEGHLQILLMFKTRPEDFRDLS FPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYSLM NITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTSCP ATVINGQFVERCWTHSHCQKVCPTICKSHGCTSEGLCCHSECLGNCSEPDDPTKCVACRN FYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQGCHQYVIHNNKCIPECPS GYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGCTVVNGSLIINIRGGNNL AAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQ LWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCEN ELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWT VVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQT DATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELYELDYCLKG LKLPSRTWSPPFEAEGSPKHNQSEHEESAGECCSCPKTDSQILKELEESSFRKTFEDYLH NVVFVPRKSSSSPGAEDTRPSRKRRALRDVANVTAAVPTAAGFPNTSTSTPTSPEERKPF EKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYVSARTMPEAKADDIVGPVT HEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRLRGLPP GNYSVRVRATSLAGNGSWTEATYFYVTDYYVPSNIAKIIIGPLIFVFLFSVVIGSIYLFL RKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYE GNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPT LVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRD LAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDM WSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKM RPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMESVPLDRASHSQREE AGGRDGGSSLGLKRNYEEHIPYTHMNGGKKNGRILTLPRSNPS NT seq 4092 nt NT seq  +upstreamnt  +downstreamnt atggcgtgtttgctcacctgtcttgcttttggcttgtttttacttctagtgtgtcccggc atggatatccggaacaacctcacgaggttgcatgagctggccaactgctcggtcattgaa ggacatttgcagatactgttgatgttcaaaacaaggcccgaggatttccgagacctcagt ttccccaaactcatcatgatcactgattacttgctgctcttccgggtctatgggctggag agcctgaaggacctgttccccaacctcacggtcatccggggctcgcgcctcttcttcaac tacgcactggtcatcttcgagatggttcacctgaaggaactcggcctctatagcttgatg aacattacccggggctccgtccgcatcgagaaaaataacgagctgtgctacctggccacc atcgactggtcgcgcatcctggattctgtggaggataattatattgtgctgaacaaagac gacaacgaggagtgtggggacatttgtccgggcacggcgaagggcaagaccagctgccct gccactgtcatcaacgggcagtttgtcgagcggtgttggacacacagccactgccagaaa gtctgtcccaccatctgcaagtcgcacggctgcacctcggagggcctctgctgccacagc gagtgcttaggcaattgctccgagcccgacgaccccaccaagtgcgtggcctgtcgcaac ttctacctggacggcaggtgcgtggagacctgcccgcccccgtactatcacttccaggac tggcgctgcgtgaacttcagcttttgccaggacctgcacaacaaatgcaagaactcccgg aggcagggctgccaccagtacgtcattcacaacaacaagtgcatccccgagtgcccctct ggttacacgatgaattccagcaacctgatgtgcactccatgcctgggcccctgtcccaag gtctgccacatcctggaaggcgagaagaccattgactcggtgacatctgcccaggagctt cgaggctgcacggtggtcaacggaagcctcatcatcaacatccgagggggcaacaacctg gcagctgagctggaggccaacctcggactcattgaggaaatttctgggtatctgaaaatc cggagatcctacgctcttgtgtcactttcctttttccggaagttacggctgattcgagga gagaccttggaaatcgggaactactctttctacgccttggacaaccagaacctaaggcag ctttgggattggagcaaacacaacctcaccatcactcaggggaaactcttcttccactat aatcccaaactctgcttgtcagaaattcacaagatggaggaagtttcgggaaccaagggg cgccaggagaggaacgacattgccctgaagaccaacggggaccaggcgtcttgtgagaac gaactccttaaattctcttacattcggacatcgtacgacaagatcttgctaaaatgggag ccatactggccccctgacttccgagaccttttggggttcatgcttttctacaaagaggcc ccttaccagaatgtgaccgagttcgacgggcaggacgcatgtggctccaacagctggacc gtggtggacattgacccccctctgcggtccaatgaccccaagtcgcagaaccacccaggg tggctgatgcggggtctcaagccctggacccagtacgccatttttgtcaagaccttggtt accttttctgatgaacgccgcacgtacggggccaagagtgacatcatctatgtgcagacg gatgccactaacccttccgtccccctggatccaatctccgtttcgaattcctcgtcccag attatcctcaagtggaaacctccctcggaccccaacggcaacatcacacactacctggtt ttctgggagaggcaggcggaagacagtgagctgtacgagctggactattgcctcaaaggg ttgaagctgccgtcccggacctggtctccgccgttcgaggctgagggctccccgaagcac aaccagagtgaacacgaggagtccgccggcgagtgctgctcctgccccaagacagactcc cagatcctcaaggagctggaggagtcctcttttaggaagacctttgaggattacctgcac aatgtggtgttcgtccccagaaaatcctcgtcaagccctggtgctgaggacactaggccg tcgcggaaacgcagggccctcagggacgtggccaacgtgacagcggccgtgcccacagct gccggtttccccaacacctcgactagcacgcccacgagcccggaggagcgcaagcctttt gagaaggtggtaaacaaggagtccctggtcatctctgggctgcgtcatttcaccggctac cgtatcgagctgcaggcttgcaaccaggacgcccccgaggagaggtgcagcgtggcggcc tatgtcagcgccaggaccatgcccgaagccaaggcagacgacatcgtcggccccgtgacc cacgaaatcttcgagaacaatgtcgttcacttgatgtggcaggagccgaaggaacccaac ggtctgattgtgctgtatgaagtcagttaccgacgctatggagatgaggagctgcacctc tgtgtctcccgcagacacttcgctctggagcgcggctgcaggctgcgcgggctgccgcca gggaattacagcgtgcgagtccgggccacctccctggcaggcaacggatcctggacagaa gccacctatttctacgtgacagactattatgtcccatcgaatattgcaaaaatcatcatc ggccccctcatctttgtctttctcttcagtgttgtgattggaagtatttacctgttcctg cggaagaggcagccggatgggccgctgggaccgctgtatgcatcttcaaaccctgagtac ctcagtgccagtgatgtgttcccatgttctgtgtatgtgccggacgagtgggaggtgcct cgggagaagatcactctcctgcgggagctggggcagggctccttcggcatggtgtacgag ggcaacgccagggacatcgtcaagggcgaggcggagacccgcgtggcggtgaagacggtc aacgagtcggccagtctgcgggagaggatcgagtttctcaacgaggcctccgtcatgaag ggcttcacctgtcatcacgtggtccgcctcctgggggtggtgtccaaaggccagccgacg ctggtggtgatggagctgatggcccacggagacctcaagagctacctccgctccctgcgg ccggaggctgagaataaccccggccgccctccccctaccctgcaagagatgattcagatg gcagcggagatcgccgacgggatggcctacctgaatgccaagaagttcgtgcaccgggat cttgcagcccggaactgcatggtggcccacgatttcaccgtcaaaattggagactttggg atgaccagagacatctatgaaacggattactaccggaaaggaggcaagggtctgctccct gtgcggtggatggcaccggaatccctgaaggacggggtctttaccacttcttctgacatg tggtcctttggcgtggtcctctgggaaatcaccagcttggcagaacagccttaccaaggc ctgtcaaatgaacaggtgttgaaatttgtcatggatggagggtatctggaccaacccgac aattgtccagagagagtcaccgacctgatgcgtatgtgctggcagttcaatcccaagatg cggcccactttcctggagatcgtcgacctgctcaaggacgacctgcaccccagctttccg gaagtttccttcttccacagcgaggagaacaaggcgcctgagagcgaggagctggagatg gagtttgaggacatggagagcgtccccctggatcgggcctcccactctcagagggaggag gccgggggccgggatggagggtcctccttgggcctaaagaggaactatgaggagcacatc ccctatacccacatgaatgggggcaagaaaaacggacggattctgactctgccgaggtcg aatccttcctaa

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