Mustela putorius furo (domestic ferret): 101678102 Help Entry 101678102         CDS       T07239                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism mpuf  Mustela putorius furo (domestic ferret) Pathway mpuf01524   Platinum drug resistance mpuf04115   p53 signaling pathway mpuf04210   Apoptosis mpuf04215   Apoptosis - multiple species mpuf04217   Necroptosis mpuf04620   Toll-like receptor signaling pathway mpuf04621   NOD-like receptor signaling pathway mpuf04622   RIG-I-like receptor signaling pathway mpuf04623   Cytosolic DNA-sensing pathway mpuf04625   C-type lectin receptor signaling pathway mpuf04657   IL-17 signaling pathway mpuf04668   TNF signaling pathway mpuf04932   Non-alcoholic fatty liver disease mpuf04936   Alcoholic liver disease mpuf05010   Alzheimer disease mpuf05016   Huntington disease mpuf05022   Pathways of neurodegeneration - multiple diseases mpuf05132   Salmonella infection mpuf05134   Legionellosis mpuf05142   Chagas disease mpuf05145   Toxoplasmosis mpuf05152   Tuberculosis mpuf05160   Hepatitis C mpuf05161   Hepatitis B mpuf05162   Measles mpuf05163   Human cytomegalovirus infection mpuf05164   Influenza A mpuf05165   Human papillomavirus infection mpuf05167   Kaposi sarcoma-associated herpesvirus infection mpuf05168   Herpes simplex virus 1 infection mpuf05169   Epstein-Barr virus infection mpuf05170   Human immunodeficiency virus 1 infection mpuf05200   Pathways in cancer mpuf05203   Viral carcinogenesis mpuf05416   Viral myocarditis mpuf05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mpuf00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     101678102 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     101678102 (CASP8)    04215 Apoptosis - multiple species     101678102 (CASP8)    04217 Necroptosis     101678102 (CASP8)    04115 p53 signaling pathway     101678102 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     101678102 (CASP8)    04621 NOD-like receptor signaling pathway     101678102 (CASP8)    04622 RIG-I-like receptor signaling pathway     101678102 (CASP8)    04623 Cytosolic DNA-sensing pathway     101678102 (CASP8)    04625 C-type lectin receptor signaling pathway     101678102 (CASP8)    04657 IL-17 signaling pathway     101678102 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101678102 (CASP8)    05203 Viral carcinogenesis     101678102 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101678102 (CASP8)    05161 Hepatitis B     101678102 (CASP8)    05160 Hepatitis C     101678102 (CASP8)    05164 Influenza A     101678102 (CASP8)    05162 Measles     101678102 (CASP8)    05168 Herpes simplex virus 1 infection     101678102 (CASP8)    05163 Human cytomegalovirus infection     101678102 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     101678102 (CASP8)    05169 Epstein-Barr virus infection     101678102 (CASP8)    05165 Human papillomavirus infection     101678102 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     101678102 (CASP8)    05134 Legionellosis     101678102 (CASP8)    05152 Tuberculosis     101678102 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101678102 (CASP8)    05142 Chagas disease     101678102 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     101678102 (CASP8)    05016 Huntington disease     101678102 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     101678102 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     101678102 (CASP8)    05416 Viral myocarditis     101678102 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     101678102 (CASP8)    04932 Non-alcoholic fatty liver disease     101678102 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     101678102 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:mpuf01002]     101678102 (CASP8) Enzymes [BR:mpuf01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      101678102 (CASP8) Peptidases and inhibitors [BR:mpuf01002]  Cysteine peptidases   Family C14: caspase family    101678102 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN COG3_C Motif Other DBs NCBI-GeneID:  101678102 NCBI-ProteinID:  XP_004764222 Ensembl:  ENSMPUG00000000240 UniProt:  A0A8U0T0N7 M3XMD7 LinkDB All DBs Position Unknown AA seq 484 aa AA seqDB search MNFSKCLYNIGEQLDSDELASLKFLSMDYIPQKKQEPIKDPLMLFQRLQEKRLLEENNLS FLKELLFRINRLDLLVTYLDTSKQEMEQELQIPGRAQISAYRVMLFQISEDVSKLELKSF KFFLSQEIPRCRVNDDSNLFDIFIEMEKRVILGERNLDTLKRICDLINRSLLKKITDYEE LSQERTMIPQRSLDEISNDMSQLLVGEKSLRIPPMSDSPREQNCGSETSDKVYQMESKPR GYCLIFNNYDFSIARKEVPKLHSIKDRNGTDLDADALHQTFSELHFEIVPFRDSTAKEIC DVLKSYQSMDHTTRDCFICCILSHGDKGIIYGCDGQGVPICELTSYFTGSKCPSLAGKPK IFFIQACQGDNYQKGIAVETDSEQNEACYESDSCQKRYIPDDADFLLGMATVNDCVSYRN PMEGTWYIQTLCQSLRERCPRGEDILSILTEVNFEVSSKDDRRNMGKQMPQPTFTLRKKL IFPL NT seq 1455 nt NT seq  +upstreamnt  +downstreamnt atgaatttcagtaaatgcctctataatattggagaacagctggacagtgatgagctggct tccctcaaattcctgagcatggactacatcccccagaagaagcaggagcccatcaaggat cccctgatgttattccagagactccaggaaaagagactgttggaggaaaacaacctgtcc ttcttgaaggagcttcttttccgaatcaacagactggacctgctggtcacctacctggac accagcaagcaggagatggagcaagagcttcagatcccgggcagagcccagatctctgct tacagggtcatgctttttcagatttcagaagatgtaagcaaactggaattgaagtccttt aagttttttttgagccaggagatccctagatgtagagtgaacgatgattcgaacttgttt gatattttcatagagatggagaagagggtcatcctcggggaaagaaatttggacaccctg aaaagaatctgtgacctaataaacaggagcctgctgaagaaaatcacggattatgaagaa ttaagccaagagcgaacaatgatcccgcaaagaagtctagatgaaatttcaaatgatatg tctcagttgcttgtaggagagaaatcgctgaggataccgccaatgtcagactctccaagg gaacagaactgtggatcagagacatcggacaaagtttaccaaatggaaagcaaacctcga ggatattgtttgatctttaacaattatgactttagcatagcacggaaggaagtgcccaaa cttcacagcattaaggataggaatggaacagacttggatgcagatgctttgcatcagacc tttagtgagcttcattttgagatcgtgcctttcagagactctacggctaaggaaatctgt gacgttctcaaatcctaccaaagcatggaccacactaccagggactgcttcatctgctgc atcctctcccatggagacaagggcatcatctacggctgtgatggacagggagtccccatc tgtgagctcacctcttacttcactggttctaagtgcccttcccttgcagggaagcccaag atcttttttattcaggcttgtcaaggggataactaccagaaggggatcgctgttgagacc gactctgaacagaatgaagcgtgttatgaatcagactcctgtcagaagagatatatccca gacgatgctgactttctgctggggatggccactgtgaatgattgtgtttcctaccgaaac cccatggagggaacgtggtatatccagacactttgccagagcctgagagaaagatgtcct aggggagaagacattctcagcatccttactgaagtgaattttgaagtgagcagtaaggat gacaggagaaacatgggcaaacagatgccacagccgaccttcacgctgcggaaaaagctc attttccccttgtga

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