Mustela putorius furo (domestic ferret): 101682422 Help Entry 101682422         CDS       T07239                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism mpuf  Mustela putorius furo (domestic ferret) Pathway mpuf04064   NF-kappa B signaling pathway mpuf04380   Osteoclast differentiation mpuf04650   Natural killer cell mediated cytotoxicity mpuf04658   Th1 and Th2 cell differentiation mpuf04659   Th17 cell differentiation mpuf04660   T cell receptor signaling pathway mpuf05135   Yersinia infection mpuf05166   Human T-cell leukemia virus 1 infection mpuf05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mpuf05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:mpuf00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     101682422 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     101682422 (LCK)    04660 T cell receptor signaling pathway     101682422 (LCK)    04658 Th1 and Th2 cell differentiation     101682422 (LCK)    04659 Th17 cell differentiation     101682422 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     101682422 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     101682422 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101682422 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     101682422 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     101682422 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mpuf01001]     101682422 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:mpuf03036]     101682422 (LCK) Enzymes [BR:mpuf01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      101682422 (LCK) Protein kinases [BR:mpuf01001]  Non-receptor tyrosine kinases   SRC family    101682422 (LCK) Chromosome and associated proteins [BR:mpuf03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     101682422 (LCK) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 SH2_1 ABC1 Haspin_kinase SH3_16 SH3_3 Motif Other DBs NCBI-GeneID:  101682422 NCBI-ProteinID:  XP_004740975 Ensembl:  ENSMPUG00000015261 UniProt:  M3YUZ1 LinkDB All DBs Position Unknown AA seq 509 aa AA seqDB search MGCSCSSNSEEDWMENIDVCENCHYPIVPLDGKATLPIRNGSEVRDPLVIYEGSNPPASP LQDNLVIALHSYEPSHDGDLGFEKGEQLRILERNGEWWKAQSLTTGQEGFIPFNFVAKAN SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH YKIRNLDQGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTPPGIKLTINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSDTLSCKIADFGLARLIVDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMMLCWKER PEDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtagctgcagctcaaactctgaagaagactggatggaaaacatcgatgtatgt gagaactgccattaccccatagtcccactggatggcaaggccacgctgcccatccgcaat ggctctgaggtgcgggatccactggtcatctatgaaggctccaaccccccagcctcacca ttgcaagacaacctggttatcgctctgcacagctacgagccctctcacgatggagacttg ggcttcgagaagggtgaacagctccgtatcctggagcggaacggcgaatggtggaaggca cagtccctgaccaccggccaggaaggtttcattcccttcaacttcgtggccaaagcgaac agcctggagcccgaaccctggttcttcaagaacctgagccgcaaggacgctgagcggcag ctcctggcgcccgggaacacgcacggctccttcctgatccgggagagcgagagcaccgcc ggatcgttttcactgtccgtgcgggacttcgaccagaaccagggagaggtggtgaaacat tacaaaatccgtaacctggaccaaggcggcttctacatctcgccccgcatcacttttcct ggcctgcacgagctggtccgccattacaccaatgcttcggacgggctgtgcacgcggttg agtcgcccctgccagacccagaagccccagaagccttggtgggaggacgagtgggaggtt cccagggagacgctgaagctggtggagcggctgggggctggccagttcggggaagtgtgg atggggtactacaacgggcacacaaaggtggcagtcaagagcctgaagcagggaagcatg tcccccgacgccttcctggccgaggccaacctcatgaagcagctgcaacaccagagactg gtccggctctacgcggtggtcacccaggagcccatctacatcatcacggaatacatggag aacgggagcctggtagatttcctcaagacccccccaggcatcaagctgaccatcaacaaa ctcctggacatggcagcccaaattgcagagggcatggcattcattgaagagcggaattat atccaccgtgacctgagggctgccaacatcctcgtttctgacaccctgagctgcaagatt gcagactttggcctagcacgcctcattgtggacaatgagtacacagccagggagggagcc aagtttcccattaagtggacagcaccggaagccattaactatgggacattcaccatcaag tcggatgtgtggtcttttgggatcctgctgacggagattgtcacccatggccgcattcct tacccagggatgaccaatcctgaggtgattcagaacctagagcgaggctaccgtatggtg cgacctgacaactgtcccgaggagctgtaccacctcatgatgctttgctggaaggagcgc ccagaggaccggcccacctttgactacctgcgcagtgtgctggaggacttcttcacggcc acagagggccagtaccagcctcagccctga

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