KEGG   Mustela putorius furo (domestic ferret): 101685370
Entry
101685370         CDS       T07239                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
mpuf  Mustela putorius furo (domestic ferret)
Pathway
mpuf01521  EGFR tyrosine kinase inhibitor resistance
mpuf01522  Endocrine resistance
mpuf04010  MAPK signaling pathway
mpuf04012  ErbB signaling pathway
mpuf04014  Ras signaling pathway
mpuf04062  Chemokine signaling pathway
mpuf04068  FoxO signaling pathway
mpuf04072  Phospholipase D signaling pathway
mpuf04150  mTOR signaling pathway
mpuf04151  PI3K-Akt signaling pathway
mpuf04380  Osteoclast differentiation
mpuf04510  Focal adhesion
mpuf04540  Gap junction
mpuf04550  Signaling pathways regulating pluripotency of stem cells
mpuf04630  JAK-STAT signaling pathway
mpuf04650  Natural killer cell mediated cytotoxicity
mpuf04660  T cell receptor signaling pathway
mpuf04662  B cell receptor signaling pathway
mpuf04664  Fc epsilon RI signaling pathway
mpuf04714  Thermogenesis
mpuf04722  Neurotrophin signaling pathway
mpuf04910  Insulin signaling pathway
mpuf04912  GnRH signaling pathway
mpuf04915  Estrogen signaling pathway
mpuf04917  Prolactin signaling pathway
mpuf04926  Relaxin signaling pathway
mpuf04935  Growth hormone synthesis, secretion and action
mpuf05034  Alcoholism
mpuf05160  Hepatitis C
mpuf05161  Hepatitis B
mpuf05163  Human cytomegalovirus infection
mpuf05165  Human papillomavirus infection
mpuf05200  Pathways in cancer
mpuf05203  Viral carcinogenesis
mpuf05205  Proteoglycans in cancer
mpuf05206  MicroRNAs in cancer
mpuf05207  Chemical carcinogenesis - receptor activation
mpuf05208  Chemical carcinogenesis - reactive oxygen species
mpuf05210  Colorectal cancer
mpuf05211  Renal cell carcinoma
mpuf05213  Endometrial cancer
mpuf05214  Glioma
mpuf05215  Prostate cancer
mpuf05220  Chronic myeloid leukemia
mpuf05221  Acute myeloid leukemia
mpuf05223  Non-small cell lung cancer
mpuf05224  Breast cancer
mpuf05225  Hepatocellular carcinoma
mpuf05226  Gastric cancer
mpuf05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mpuf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101685370 (GRB2)
   04012 ErbB signaling pathway
    101685370 (GRB2)
   04014 Ras signaling pathway
    101685370 (GRB2)
   04630 JAK-STAT signaling pathway
    101685370 (GRB2)
   04068 FoxO signaling pathway
    101685370 (GRB2)
   04072 Phospholipase D signaling pathway
    101685370 (GRB2)
   04151 PI3K-Akt signaling pathway
    101685370 (GRB2)
   04150 mTOR signaling pathway
    101685370 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101685370 (GRB2)
   04540 Gap junction
    101685370 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    101685370 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    101685370 (GRB2)
   04660 T cell receptor signaling pathway
    101685370 (GRB2)
   04662 B cell receptor signaling pathway
    101685370 (GRB2)
   04664 Fc epsilon RI signaling pathway
    101685370 (GRB2)
   04062 Chemokine signaling pathway
    101685370 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101685370 (GRB2)
   04912 GnRH signaling pathway
    101685370 (GRB2)
   04915 Estrogen signaling pathway
    101685370 (GRB2)
   04917 Prolactin signaling pathway
    101685370 (GRB2)
   04926 Relaxin signaling pathway
    101685370 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    101685370 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    101685370 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101685370 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    101685370 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101685370 (GRB2)
   05206 MicroRNAs in cancer
    101685370 (GRB2)
   05205 Proteoglycans in cancer
    101685370 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    101685370 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    101685370 (GRB2)
   05203 Viral carcinogenesis
    101685370 (GRB2)
   05231 Choline metabolism in cancer
    101685370 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101685370 (GRB2)
   05225 Hepatocellular carcinoma
    101685370 (GRB2)
   05226 Gastric cancer
    101685370 (GRB2)
   05214 Glioma
    101685370 (GRB2)
   05221 Acute myeloid leukemia
    101685370 (GRB2)
   05220 Chronic myeloid leukemia
    101685370 (GRB2)
   05211 Renal cell carcinoma
    101685370 (GRB2)
   05215 Prostate cancer
    101685370 (GRB2)
   05213 Endometrial cancer
    101685370 (GRB2)
   05224 Breast cancer
    101685370 (GRB2)
   05223 Non-small cell lung cancer
    101685370 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    101685370 (GRB2)
   05160 Hepatitis C
    101685370 (GRB2)
   05163 Human cytomegalovirus infection
    101685370 (GRB2)
   05165 Human papillomavirus infection
    101685370 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    101685370 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101685370 (GRB2)
   01522 Endocrine resistance
    101685370 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mpuf04131]
    101685370 (GRB2)
Membrane trafficking [BR:mpuf04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    101685370 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 DUF7145 SH2_2 DUF5093 hSH3 SH3_4 DUF7063
Other DBs
NCBI-GeneID: 101685370
NCBI-ProteinID: XP_004748991
Ensembl: ENSMPUG00000013882
UniProt: M3YR20
LinkDB
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgctgacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagaa
ctcaatgggaaagatggcttcatccccaagaattacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcatgac
ggggcctttctcatccgagagagtgagagtgccccaggggacttctccctctctgtcaag
tttggaaatgacgtgcagcacttcaaggtgctccgagatggagcaggaaagtatttcctc
tgggtggtgaaattcaattccctgaacgagctggtagattatcacagatcgacatctgtc
tccaggaaccagcagatattcctccgggacatagaacaggtgccacagcaaccgacgtac
gtccaggccctctttgactttgatccccaggaggatggagagctgggattccgccgggga
gactttatccacgtcatggataactcggaccccaactggtggaaaggggcctgccacggg
cagaccggcatgttcccccgcaattacgtcacccccgtgaaccggaacgtctaa

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