Mycobacterium tuberculosis H37Ra: MRA_0106 Help Entry MRA_0106          CDS       T00540                                  Symbol nrp2 Name (GenBank) putative peptide synthetase   KO K28320   isonitrile lipopeptide synthase [EC:2.3.1.329] Organism mra  Mycobacterium tuberculosis H37Ra Brite KEGG Orthology (KO) [BR:mra00001]  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:mra01008]     MRA_0106 (nrp2) Enzymes [BR:mra01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.329  isonitrile lipopeptide synthase      MRA_0106 (nrp2) Polyketide biosynthesis proteins [BR:mra01008]  Nonribosomal peptide synthetase (NRPS)   Nonlinear NRPS    Isonitrile lipopeptide synthase     MRA_0106 (nrp2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AMP-binding Condensation NAD_binding_4 PP-binding AMP-binding_C Epimerase 3Beta_HSD GH3 Polysacc_synt_2 Motif Other DBs NCBI-ProteinID:  ABQ71825 UniProt:  A5TYH5 LinkDB All DBs Position 111665..118897 Genome browser AA seq 2410 aa AA seqDB search MRHTVHTDPNGYVTGLDVHTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLR EAHRRETAKVEESRGRLSAVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNA FDAILTLSEAQRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNS VAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIR EPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAE RIAAALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFL GRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVR TNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSG TTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAI RCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTV FLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRK DAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRI RLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIW SRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTP DAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEAL GAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAA RHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAP DWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVA DQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR SDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPT RALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAG IGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRA VLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPG ECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSR LAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFAS LPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVS VLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISA PLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRF VACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVG QAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTV NGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAA MRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASD LTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVR AESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETV DLIVDSAAMVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTE DADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQ LNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGS SLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRR HSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINY VTNLQLLGLL NT seq 7233 nt NT seq  +upstreamnt  +downstreamnt gtgcggcatacggtgcacaccgacccgaacgggtatgtgaccggtctggacgttcacacc caccacatcctgctggacggcggcgcgaccgggacgatcgaagctgacctggcgcgttac ctgaccaccgacccggcgggcgaaacccccagtgtcggtgcgggtctagccaagctcagg gaggcgcaccgtcgtgagacggccaaggtggaagaatcgcgggggcgcctgtcggctgtc gtgcagcgtgaactcgccgacgaagcataccacggcgggcacgggcacagcgttagcgac gctcccgggaccgcggccaagggcgtcctgcacgaatcggcaacgatctgcggcaacgcg tttgatgccatcctgaccctttcggaagcgcagcgggtcccgcttaatgtgctggtggct gcggcggccgtcgcggtggacgcgagccttcggcagaacaccgaaaccctcttggtgcac acggtggacaaccggttcggagattctgatctgaatgtcgcgacctgtttggtcaattcg gttgcccagaccgtccggtttcccccatttgcgtcggtgtccgatgtcgttcgaacgctt gaccgcggctatgtcaaggcggtaagacgccggtggcttcgtgaggagcattaccgccga atgtatttggcgatcaaccggacatctcacgtggaggcgttgacgctaaatttcattcgc gagccatgcgcacctggcctgcgcccgttcttgtcggaggtcccgattgccacggatatc ggtccggtcgagggcatgacggtggcgtctgttctggacgaagaacagcgcacactgaac ctagccatctggaaccgagccgatctgcccgcgtgcaagacacaccccaaggtcgcggaa cggatagcggcagcgttggaatcgatggcggcgatgtgggatcggccgatcgccatgatc gtcaacgactggttcgggatcggcccggacgggactcgctgccaaggcgattggccagcc cgtcagccgtcgacgcccgcgtggtttctcgattccgcaaggggcgtccaccaatttctc ggcaggcgccgcttcgtctacccgtgggtcgcgtggttggtgcaacgcggcgccgcaccg ggtgatgttctggtgttcaccgacgacgacaccgacaagaccattgacctgctcatcgcg tgtcaccttgcgggttgcgggtacagcgtctgcgacaccgctgacgaaatttccgtgcgg accaatgcgattaccgagcacggcgatggcatcttggtgacagtggtcgacgtggccgcc acccagctggcggttgtcggccatgacgagctgcggaaggtcgttgacgagcgcgtcaca caggtgacacacgacgcactgctggccaccaagaccgcctacatcatgccgacctcggga actaccggacaacccaagctggtgcgaatctcacacggctcgctcgcggttttctgtgat gcgatcagccgcgcctacggttggggagcccacgacaccgttctgcagtgcgctccgttg acatcggacatcagcgtcgaggagattttcggtggcgcggcctgtggcgcgcgactggtg cgatccgcggctatgaaaaccggcgacctggcggcgctggttgacgatctcgtcgcccgc gagacgacaatcgtcgacctgccgaccgccgtctggcagctgttgtgcgccgacggcgac gccattgacgcgatcggccgctcgcgcctgcggcagatcgtaatcggcggtgaagccatc cgctgtagcgccgtggacaagtggcttgaatcggctgcttcacaagggatctcgctgctc tcgagctatggtccaacagaagccacggtcgtcgccaccttcttgccgatcgtttgcgac cagaccaccatggacggcgcactgctcaggctcggccggccgatcctaccgaacacggtg ttcctcgcgttcggtgaagtcgtcattgtcggggatttagtcgccgacggctacctcggg atcgacggcgacggcttcggcaccgtgacggccgcagacggttcccgacgccgtgccttt gccactggcgaccgggtgaccgtcgacgccgaaggatttccggtcttctccggacgcaaa gacgccgtcgtcaagatctccggcaagcgtgtcgatatcgctgaggtaaccaggcgcatc gccgaagaccccgcggtgtcagatgtcgccgtcgagttgcacagcggaagcctcggagtg tggttcaagagccaacggacccgcgagggcgaacaagacgctgccgcggcgacccggatc aggctcgtcctcgtgagtctgggagtgtcgtcgtttttcgttgtcggcgtgccgaatatc ccgaggaagcccaacgggaagatcgacagcgacaacctgccgaggctgcctcagtggtca gctgctgggctaaacaccgccgagacgggtcagcgagcggccggcctctcgcagatctgg agccggcagctcggccgggcaatcgggccggactcgtcgctgcttggtgagggcatcggc tcgttggatctcatcagaatactgcccgagacgcgtaggtatctggggtggcgcctctcg ctgctggatctgatcggtgccgataccgccgccaatctggccgattacgcgccaacgccc gacgcgccgacgggcgaagatcggtttaggccgctggtggccgcgcaacggcccgcggcg attccgttgtcgtttgcccagcggcgactatggtttctcgaccagttacagcgacccgct ccggtctacaacatggcggtggcgttgcggctgcgcgggtatctcgataccgaggcgttg ggcgcggcggtcgccgatgtcgtgggccgccacgaaagcctacggacggtgtttccggcg gtcgacggggtccctcggcagctggtcatcgaagcgcggcgggcagatcttggctgcgac atcgtcgatgccaccgcatggccggctgaccggctgcaacgggccatcgaggaggcggcg cgccacagcttcgatttggcaaccgagatacctttgcggacgtggcttttccggatcgcc gacgacgaacatgtgctggtggcggttgcacaccatatcgccgccgacggctggtcggtg gctccgctgacggccgatctgagtgcggcatatgccagccgttgtgcgggtcgggcaccg gactgggcgccattgccagtgcagtatgtcgattacacgctgtggcagcgggaaatcctc ggtgatctcgacgacagcgacagcccgatcgccgcgcagctggcctactgggaaaatgcg ttggccggtatgccggaacggctgcggctgcccaccgctcggccctatccaccggttgcc gatcagcgcggcgccagtttggtggtggattggccggcgtcggtgcaacagcaggtgcgt cggatcgcccgccagcacaacgcgaccagcttcatggtggtagctgccgggcttgccgtg ctgctgtcgaaactcagcggaagccccgatgtggcggtcggatttcccatcgccggccgc agcgatcctgcgctggataacttggtgggcttttttgtcaacaccttggtgttgcgggtc aacctggccggtgatcccagcttcgccgaactgctggggcaggtgcgagcgcgcagcctg gccgcctacgaaaatcaagacgtacctttcgaggtgctcgttgatcgcctcaaacccact cgagccctgacccatcacccgctgatccaggtgatgttggcctggcaggacaatccggtt ggacagctgaatttgggtgatctgcaggccaccccgatgccgatcgacacccgcaccgcc cgcatggacttggtgttttcgttagcggaacgcttcagcgagggtagcgaacctgccggg atcggcggagcggtggaataccgcaccgatgtgtttgaagcccaagcaatcgacgtgctt atcgagcggttgcggaaggtgttggtggcggtggccgctgctccggaacggacggtgtcg tcgatcgatgcgctggatgggaccgagcgtgcccggttggatgagtggggtaaccgcgct gtgctgactgcgcccgcgcccacgccggtgtcgatcccgcagatgttggccgcccaggtg gcacgtatccccgaagcggaggcggtgtgttgcggggacgcgtcgatgacgtatcgggaa ctcgacgaggcgtccaaccggttagcgcatcggctggcaggttgtggggccggcccgggc gagtgtgtggcgctgctgttcgagcggtgcgcgccggcggtcgtggcgatggtggcagtg ctcaaaaccggggcggcgtatctgccgatcgatccggcgaatcctccgccgcgggtggcg ttcatgctcggcgacgcggtgcccgtggccgcggtcaccacggctgggctgcgctcccgg ttggcgggacacgacttgccgatcatcgatgtcgtcgatgctttagcggcatatccgggc acgcccccacccatgccggccgcagtgaacctcgcctacatcctgtacacctcgggcact accggcgagcccaaaggcgtggggatcacccatcgcaacgtcaccaggctgttcgcatca ctgccggcacgcttgtcggcggcgcaggtgtggtcgcagtgtcattcctatggcttcgac gcctcggcgtgggagatctggggcgcgttgctaggtggtgggcgactggtgatcgtgccc gagtcggtggcggcctcgccgaacgactttcatgggctgctcgtggccgaacacgtcagc gtgctgactcagactccggctgcggtggcaatgttgccgacgcagggtttggagtcggtg gcgttggtggtggccggtgaggcatgtccggcagcgctggtggatcggtgggcgcccggg cgggtgatgctaaatgcttatggcccaaccgagaccacgatctgtgcggcgataagtgcg ccgttgcgaccgggttcggggatgccgccgattggtgttccggtgtcgggggcggcgttg tttgtgctggatagctggttgcgcccggtaccggccggggtggccggagagttgtacatt gccggtgcgggcgtcggtgttgggtattggcgtcgggcggggctgaccgcgtcacggttt gtggcctgcccattcggcggttccggggcacgcatgtatcgcaccggggatctggtgtgt tggcgcgccgatggccagttggagttcctggggcgcaccgacgatcaggtcaagatccgc gggtatcgcatcgagctcggcgaggttgcgaccgcgctggccgagctggctggggtaggt caagcggttgtaatcgcccgtgaagaccgccctggggacaagcgcctagtcgggtatgcc accgaaattgcccccggggcagtggacccggccgggctgcgggcgcaactagcccagcga ttgcccggttacctggtgccagccgcggtggtagtgatcgatgcgcttccgttgacggtc aacggcaaacttgatcatcgtgcgttgccggcaccggaatacggtgataccaacggatat cgcgctccggccgggccggttgagaagaccgtggccggcatctttgcccgggtgcttggg cttgagcgggtcggcgtcgacgactcgttcttcgagctcggcggcgattcgctggcggca atgcgggttatcgccgcgatcaacaccaccctaaacgccgatctgccggtgcgcgcgttg ctgcacgcgtcgtcgacgagaggtttaagccagctgttggggcgagatgcccgaccgacc agcgatccgcgcttggtgtctgtgcacggcgacaaccccaccgaggtgcatgccagcgac ctcacgctggaccggttcatcgacgccgacacgctggccaccgccgtcaacctgccgggc ccgagccccgagctacggacggtcctgctgacgggcgcgacgggtttcctcggacggtat ctggtccttgaattgctgcggcggctggacgtcgacggcaggctgatctgtttggtgcgg gcggagtccgacgaggatgcgcggcgtcgtctggagaagaccttcgatagcggtgacccg gaattgctgcggcacttcaaggagcttgccgccgaccggctggaggtcgtcgcaggcgac aagagcgaacccgacctgggcctggaccaaccgatgtggcggcggctggccgaaaccgtg gatttgattgtcgattccgcggcgatggtcaacgcgtttccctaccacgaattgttcggg cccaacgtcgcgggcaccgccgagctgatccgaatcgcgcttaccaccaagctcaaaccc ttcacctacgtgtcaaccgccgacgtgggtgctgcgatcgagccgtcggcgttcaccgag gacgccgacatccgggtaatcagccccacccgcaccgtcgacggcggctgggctggcggc tacggcaccagcaagtgggccggtgaggtgctgctgcgcgaggccaacgacctgtgcgcg ctgccggtcgcggtgtttcgctgcgggatgatcctggccgacaccagctatgccggacag ctcaacatgtcggactgggtcacccggatggtgttgagcttgatggctaccggcatcgcg cctcgttcgttctacgaaccggactccgagggcaatcggcaacgcgcgcacttcgacggg ctgccagtcaccttcgttgccgaggcgatcgcggtgctgggcgcgcgggtggccggctca tcgttggcgggatttgcgacctatcacgtgatgaacccgcacgacgacggtatcgggctc gatgagtatgtggactggctgattgaggccggctacccgatacgccgcatcgatgacttt gcggagtggttgcagcggtttgaggccagcctgggcgctctgccggatcggcaacgccgg cactcggtgctgccgatgctgctggcgagcaattcccagcgattgcagccgcttaagccg accagggggtgctccgcgccgaccgaccgattccgtgccgcggtgcgagcggcgaaagtc ggctccgacaaggacaatccagacatcccgcacgtgtcggcgccgaccatcatcaactac gtcaccaacctacaactgctcggactgctgtag

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