Mycobacterium tuberculosis H37Ra: MRA_3436
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Entry
MRA_3436 CDS
T00540
Symbol
guaA
Name
(GenBank) bifunctional GMP synthase/glutamine amidotransferase protein
KO
K01951
GMP synthase (glutamine-hydrolysing) [EC:
6.3.5.2
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00230
Purine metabolism
mra00983
Drug metabolism - other enzymes
mra01100
Metabolic pathways
mra01232
Nucleotide metabolism
Module
mra_M00050
Guanine ribonucleotide biosynthesis, IMP => GDP,GTP
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MRA_3436 (guaA)
09111 Xenobiotics biodegradation and metabolism
00983 Drug metabolism - other enzymes
MRA_3436 (guaA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mra01002
]
MRA_3436 (guaA)
Enzymes [BR:
mra01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.2 GMP synthase (glutamine-hydrolysing)
MRA_3436 (guaA)
Peptidases and inhibitors [BR:
mra01002
]
Cysteine peptidases
Family C26: gamma-glutamyl hydrolase family
MRA_3436 (guaA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase
GMP_synt_C
NAD_synthase
Peptidase_C26
tRNA_Me_trans
Asn_synthase
QueC
ThiI
HHH_2
Arginosuc_synth
ATP_bind_3
Motif
Other DBs
NCBI-ProteinID:
ABQ75221
UniProt:
A5U871
LinkDB
All DBs
Position
complement(3821179..3822756)
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AA seq
525 aa
AA seq
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MVQPADIDVPETPARPVLVVDFGAQYAQLIARRVREARVFSEVIPHTASIEEIRARQPVA
LVLSGGPASVYADGAPKLDPALLDLGVPVLGICYGFQAMAQALGGIVAHTGTREYGRTEL
KVLGGKLHSDLPEVQPVWMSHGDAVTAAPDGFDVVASSAGAPVAAFEAFDRRLAGVQYHP
EVMHTPHGQQVLSRFLHDFAGLGAQWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAV
AAALVQRAIGDRLTCVFVDHGLLRAGERAQVQRDFVAATGANLVTVDAAETFLEALSGVS
APEGKRKIIGRQFIRAFEGAVRDVLDGKTAEFLVQGTLYPDVVESGGGSGTANIKSHHNV
GGLPDDLKFTLVEPLRLLFKDEVRAVGRELGLPEEIVARQPFPGPGLGIRIVGEVTAKRL
DTLRHADSIVREELTAAGLDNQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDA
MTADWTRVPYEVLERISTRITNEVAEVNRVVLDITSKPPATIEWE
NT seq
1578 nt
NT seq
+upstream
nt +downstream
nt
gtggtgcagcctgctgacatcgacgtgcctgagacaccggctcgaccggtgttggtggtc
gacttcggtgcccaatatgcccagttgattgcccgtcgggttcgagaagcacgggttttc
tccgaggtgattccgcacaccgcctcgatcgaggagatcagggcccgtcagccggtggcg
ctcgtgctttccggtggaccggccagtgtctacgccgacggcgctccgaaactcgatccg
gcgctactggacctcggtgtaccggttcttggcatctgctacgggtttcaggccatggcg
caggcgctcggggggatcgtcgcccacaccggcactcgcgaatacggtcggactgaactg
aaagtccttggtggcaaactgcattcggatcttcccgaggttcagccggtatggatgagt
cacggtgacgcggtcacggccgcgccggacggattcgacgtggtggctagcagcgccggt
gccccggtggccgccttcgaggccttcgaccggcgcctggccggggtgcagtatcacccg
gaggtgatgcacaccccacacgggcaacaggtgctcagccggtttttgcacgacttcgcc
gggctcggcgcccagtggacgcccgccaacatcgccaacgcgctgatcgagcaggtgcgc
acccagatcggcgacggccacgccatctgcgggctatccggcggcgtggattccgcggtg
gccgcggccctggtgcagcgggccatcggcgaccggttgacctgtgtcttcgtcgaccac
gggctgttgcgcgccggtgagcgggcgcaggtgcaacgcgatttcgtggccgccaccggc
gccaacctggtcaccgtcgacgcggccgagaccttcctcgaggcgctgtcgggcgtgagc
gcccccgagggcaaacgcaagatcatcggccgtcagttcatccgcgcgttcgagggcgcg
gtgcgggatgtgctggacggtaagactgctgagttcctggtgcagggcacgctgtatccg
gatgtggtggagtccggcgggggcagcggcaccgcgaacatcaagagccaccacaatgtc
ggcggcctgcccgacgacctgaagttcaccctcgttgagccgctgcggctgctgttcaaa
gacgaggtgcgcgcggtcgggcgggagttgggtctgccggaggagatcgtggcgcgccag
ccgtttccgggaccggggttgggtattcggatcgtcggggaggtcaccgccaagcggttg
gatacgctgcggcacgccgattcgatcgtgcgtgaggagctgaccgcggcgggcctggac
aaccagatctggcagtgtccggtggtgctgttggccgatgtccgctcggtgggtgtgcag
ggtgacggtcgcacctatggccacccgattgtgctgcgtccggtgtcgagtgaagacgcg
atgaccgccgactggacccgggtgccctacgaggtgctcgagcgcatctcgacccggatc
accaacgaggtcgccgaggtcaaccgcgtggtgctggacatcaccagcaagccgcccgcc
accatcgagtgggagtag
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