Methylobacterium radiotolerans: Mrad2831_5613
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Entry
Mrad2831_5613 CDS
T00674
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mrd
Methylobacterium radiotolerans
Pathway
mrd00010
Glycolysis / Gluconeogenesis
mrd00020
Citrate cycle (TCA cycle)
mrd00620
Pyruvate metabolism
mrd00785
Lipoic acid metabolism
mrd01100
Metabolic pathways
mrd01110
Biosynthesis of secondary metabolites
mrd01120
Microbial metabolism in diverse environments
mrd01200
Carbon metabolism
mrd01210
2-Oxocarboxylic acid metabolism
Module
mrd_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mrd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Mrad2831_5613
00020 Citrate cycle (TCA cycle)
Mrad2831_5613
00620 Pyruvate metabolism
Mrad2831_5613
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Mrad2831_5613
Enzymes [BR:
mrd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Mrad2831_5613
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ACB27558
UniProt:
B1M0N6
LinkDB
All DBs
Position
complement(5943940..5946615)
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AA seq
891 aa
AA seq
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MNAIPPKATIARSAEVDHDPAETQDWLAALESVFRTEGAARARFILDRLERRSKEIGILD
EALPYSPYRNTIALEKQPRYPGDLDIEERLTSIMRWNALAMVVRANMAYGELGGHVASYA
SAAELFEVGFNHFFKGGTDGDLVYFQPHSAPGVYARAFLEGRLSEEQLKHYRQEIAGDGL
CSYPHPWLMPDFWQVPTGSMGIGPIHAVYQARFMRYLGDRGLADTAGRHVWGVFGDGEMD
EPESIGGLALAARENLDNLTFVINCNLQRLDGPVRGNGQIIQELESLFRGAGWNVIKVLW
GSEWDGIFARDTNHALLRRFAETVDGKYQTLGAKDGAYNLAHFFGEDPEVRELVAHMSDA
DVDRLKRGGHDFRKLYAAFAAAKATKGRPTVILAKTKKGYGMGGAGESRMTAHQAKKLDV
DALRAFRDRFALPLSDAQVEGLAFYKPAEDGAEMRYLRERRETLGGVLPARRRTAPTVAV
PALSTYAGFALEAGGKEMSTTTAVVRLFGNLLKHKDLGPRIVPIVADEARTFGMANLFRQ
VGIYAPQGQLYEPEDAGSMLYYREARDGQLLEEGITEAGAISSWTAAATSYSVHGLSMLP
FYIYYSMFGFQRVGDLIWAAADQRARGFLIGATAGRTTLGGEGLQHQDGSSHMQAAAIPN
CRAYDPAFAYEMAVIVDRGARAMMEEGEDAFYYLTAMNENYAQPSMPQGAEAGILKGMYR
LSGPEAGSAAVRLLGSGAILPEVIAAAALLAQDFGVAAEVFSVTSFSELARDAREAERQA
MLNPEAEAPVSHVAALLPGPAPVVAASDYVRAYPQLIASYVGARFVALGTDGFGRSDTRN
ALRRFFEVDRQHVVVAALHALAEAGTVPRATVADAIRRYSIAADAPAPWTI
NT seq
2676 nt
NT seq
+upstream
nt +downstream
nt
atgaacgccataccgccgaaagccacgatcgcgcggtccgccgaggtggatcacgacccg
gccgagacccaggactggctcgccgcgctggaatccgtcttccgcaccgagggcgcggcc
cgggcccggttcatcctcgaccgcctggagcggcgctcgaaggagatcggcatcctcgac
gaggccctgccctactcgccctaccggaacacgatcgcgctggagaagcagccgcgctac
cccggcgacctcgacatcgaggagcgcctgacctcgatcatgcgctggaacgccctcgcc
atggtggtgcgcgccaatatggcctacggcgagctcggcggccacgtggcgagctacgcc
tcggcggcggagctgttcgaggtcgggttcaaccacttcttcaagggcggcacggacggc
gacctcgtctatttccagccgcactcggcgccgggcgtctacgcccgggccttcctcgag
ggccggctctccgaggagcagctgaagcactaccgccaggagatcgccggcgacgggctg
tgctcctacccgcatccctggctgatgccggatttctggcaggtccccaccggctcgatg
ggcatcgggccgatccacgcggtctaccaggcgcgattcatgcgctacctcggcgaccgg
ggcctcgccgacaccgccggccgccacgtctggggcgtgttcggcgacggcgagatggac
gagcccgagtcgatcggcggcctcgcgttggcggcacgcgagaatctcgacaacctgacc
ttcgtcatcaactgcaacctgcagcggctcgacgggccggtgcgcggcaacggccagatc
atccaggagctggagagcctgttccgcggcgccggctggaacgtcatcaaggtgctgtgg
ggctcggagtgggacgggatcttcgcccgcgacaccaaccacgccctgctgcgccgcttc
gccgagacggtggacggcaagtaccagacgctcggcgccaaggacggcgcctacaacctc
gcgcacttcttcggcgaggacccggaggtgcgcgagctcgtcgcccacatgtcggacgcc
gacgtcgaccggctgaagcgcggcggccacgacttccgcaagctctacgcggccttcgcg
gccgccaaggccaccaagggccggccgacggtgatcctggccaagaccaagaagggctac
ggcatgggcggcgcgggcgagtcgcgcatgaccgcccaccaggccaagaagctcgacgtc
gacgcgctgcgggcgttccgcgaccggttcgccctgccgctgtcggatgcccaggtggaa
ggtctcgccttctacaagccggccgaggacggcgccgagatgcgctacctgcgcgagcgc
cgggagacactcggcggcgtcctgccggctcgccgccgcaccgcgccgaccgtcgcggtt
ccggcgctctccacttacgcgggcttcgccctggaggccggcggcaaggagatgtcgacg
accacggcggtggtgcgcctgttcggcaacctcctgaagcacaaggatctcgggccgcgc
atcgtgccgatcgtcgccgacgaggcgcggaccttcggcatggccaacctgttccggcag
gtcgggatttacgcgccgcaggggcagctctacgagccggaggatgccggctccatgctc
tactaccgcgaggcccgggacgggcagctattggaggagggcatcaccgaggccggggcg
atctcgtcctggaccgcggcggccacgtcctacagcgtccacggcctgtcgatgctgccg
ttctacatctactactcgatgttcggcttccagcgggtcggcgacctgatctgggcggcg
gccgaccagcgggcccgcggcttcctgatcggcgccacggcgggccgcacgacgctcggc
ggcgagggcctgcagcatcaggacggatcgagccacatgcaggccgccgcgatcccgaac
tgccgggcctacgatccggccttcgcgtacgagatggcggtgatcgtcgaccggggggcc
cgggcgatgatggaggagggcgaggacgctttctactacctcaccgcgatgaacgagaac
tacgcccagccctccatgccgcagggagcggaggccgggatcctgaagggcatgtaccgc
ctgtcggggcctgaggcgggaagcgccgccgtgcgcctcctcggctccggagcgatcctg
ccggaggtgatcgcggcggcggcgctgctcgcgcaggatttcggcgtcgcggccgaggtg
ttcagcgtgacgagcttcagcgagctggcccgcgatgcccgcgaggccgagcggcaggcg
atgctcaacccggaggccgaggcgccggtcagccacgtggcggcgctgctgccgggcccg
gcgcccgtcgtcgcggcgagcgactacgtccgggcctacccgcagctgatcgcctcctat
gtcggcgcgcgattcgtcgccctcggcaccgacgggttcgggcggagcgacacccgcaac
gcgctccgccgcttcttcgaggtcgaccggcagcacgtcgtcgtcgccgccctgcacgcc
ctcgccgaggccggcacggtgccgcgtgcgacggtggcggacgcgatccgccgctacagc
atcgcggcggacgcgcccgcgccctggacgatctga
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