Muntiacus reevesi (Reeves' muntjac): 136148989
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Entry
136148989 CDS
T10466
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
mree Muntiacus reevesi (Reeves' muntjac)
Pathway
mree01524
Platinum drug resistance
mree03440
Homologous recombination
mree03460
Fanconi anemia pathway
mree04120
Ubiquitin mediated proteolysis
mree04151
PI3K-Akt signaling pathway
mree05206
MicroRNAs in cancer
mree05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
mree00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
136148989 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
136148989 (BRCA1)
03460 Fanconi anemia pathway
136148989 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
136148989 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
136148989 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
136148989 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
136148989 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mree01009
]
136148989 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
mree04121
]
136148989 (BRCA1)
03036 Chromosome and associated proteins [BR:
mree03036
]
136148989 (BRCA1)
03400 DNA repair and recombination proteins [BR:
mree03400
]
136148989 (BRCA1)
Enzymes [BR:
mree01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
136148989 (BRCA1)
Protein phosphatases and associated proteins [BR:
mree01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
136148989 (BRCA1)
Ubiquitin system [BR:
mree04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
136148989 (BRCA1)
Multi subunit type E3
BRCC complex
136148989 (BRCA1)
Chromosome and associated proteins [BR:
mree03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
136148989 (BRCA1)
DNA repair and recombination proteins [BR:
mree03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
136148989 (BRCA1)
BRCA1-A complex
136148989 (BRCA1)
BRCA1-B complex
136148989 (BRCA1)
BRCA1-C complex
136148989 (BRCA1)
BRCA complex
136148989 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
136148989 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_2
zf-C3HC4_3
zf-RING_5
RING_XB3-XBAT31
BRCT_2
zf-RING_6
zf-Nse
zf-ANAPC11
zf-RING_10
zf-rbx1
Prok-RING_4
RTT107_BRCT_5
zf-RING_4
Baculo_IE-1
Motif
Other DBs
NCBI-GeneID:
136148989
NCBI-ProteinID:
XP_065764839
LinkDB
All DBs
Position
18:19337696..19405883
Genome browser
AA seq
758 aa
AA seq
DB search
MDLSVDHVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLKIVHAFELDTGLQFANSYNFSRKENKSPEHLKE
EVSIIQSMGYRNRAKRLWQSEPENPTLQETGLTVELSNLGIVRSLRTKQQIQSQNKSVYI
ELGSDSSEDTVNKASYFSVGDHELLEITPQGTKAETNLNPAKKAACEFSEKDITDTEHHQ
FSIKDLITTQKHTTETHPEKYQGEAASNHVSETSLSEDSVGLSSQSDILTTQQRDTMQDN
LLKLQQEMAELEAVLEQHGSQPSHSSASLTADSRGPEHLLNPEQNTSERAILTSEKSRDY
SRSQNPESLSADKFPVSLDSSTNKNKEPGMEGSSPSKFQLSDNRWYVHSHSRSLQDRNCP
SQKESINVADMEEQQLAKCEAQDLMGSYLPQDEEGTPYLKSGISLFSHDLESDPSEDRAP
EPAHVHSMPPSASAPKLSQFRVEESTKNPAATHITNTTGCNLREESVSKEKPEVISSTER
SNKRLSLVASGLTPKELMLVQKFARKHHVTLTNLITEETTHVIMKTDPEFVCERTLKYFL
GIAGGKWVVSYFWVTQSIKERKMLDEHDFEVRGDVVNGRNHQGPKRARESQDKKIFKGLE
ICCYGPFTNMPTDQLEWMVQLCGASVVKEPSSFTPGQGTHPVVVVQPDAWTEDAGFRVIG
QMCEAPVVTREWVLDSVALYHCQELDTYLVPQVAQSCC
NT seq
2277 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctgtggatcatgttgaggaagtacaaaatgtccttaatgctatgcagaaa
atcttagagtgtccaatatgtctggagttgatcaaagaacctgtctctacaaagtgtgac
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacaa
tgtcctttgtgtaagaatgatataaccaaaagaagcctacaagaaagtacaagatttagt
caacttgttgaagagctgttgaagattgttcatgcttttgagctagacacaggattgcag
tttgcaaacagctataacttttcgagaaaggaaaataagtctcctgagcatctgaaggag
gaagtttctatcatccaaagtatgggctaccggaatcgggccaaaagactttggcagagt
gaacctgaaaatcctaccttgcaggaaaccggtcttactgtcgaactctctaaccttgga
attgtgagatctctgaggacaaagcagcagatacaatctcagaataagtccgtctacatt
gaattgggatctgattcttctgaagacacagttaataaggccagttatttcagtgtggga
gaccacgaattgttagaaatcacccctcaaggaaccaaggcagagaccaatttgaatcct
gcaaaaaaggctgcttgtgagttttctgagaaggacataacagatactgaacatcatcag
ttcagtattaaagatctgatcaccacccagaagcatacaactgagacacatccagaaaag
tatcagggtgaagcagcatccaaccatgtgagtgaaacaagcctctctgaagactctgtg
gggctgtcttctcagagtgatatcttaaccactcagcagagggataccatgcaagataac
ctactaaagctccagcaggaaatggccgagctggaagctgtgttagagcagcacgggagc
cagccttcccacagctctgcttccctcacagctgattctcgtggcccagagcacctgcta
aatccagagcaaaacacatcagaaagagcaatattaacttcagagaaaagtagagactat
tctagaagccagaatcctgaaagcctctctgctgacaagtttccagtatctctggatagt
tctaccaataaaaataaagaaccaggaatggaagggtcttccccttctaaattccagttg
tcggataataggtggtatgtgcacagccactcaaggagtcttcaggacagaaactgccca
tctcaaaaagagtccattaatgttgctgacatggaggagcaacagctggctaagtgtgag
gcccaagatttaatggggtcttatttgccacaagatgaagaaggaaccccttacctgaaa
tctggaatcagcctcttctctcatgacctcgagtctgatccctctgaagacagagcccca
gagccagctcatgttcacagcatgccaccctctgcctctgcaccgaaattatcccaattt
cgagtagaagaatctaccaagaatccagctgctactcacattactaatactacagggtgt
aacctgagggaagaaagtgtgagcaaagagaagccagaagtgatatcttcaacagaaaga
agcaacaaaagactttctttggtggcatcaggcttgaccccaaaagaactcatgcttgtg
cagaagtttgccagaaaacatcacgtcactttaactaatctaattactgaagagactact
catgtcattatgaaaacagatcctgagtttgtgtgtgaacggacactgaaatattttctg
ggaattgcaggaggaaaatgggtagttagctatttttgggtcacccagtctattaaagaa
agaaagatgctggatgagcatgattttgaagtcagaggagatgttgtcaatggaagaaac
catcaaggcccaaagcgagcaagagaatcccaagacaagaagatcttcaagggcctagag
atctgttgctatggaccttttaccaatatgcccacagatcaactagagtggatggtgcag
ctgtgtggggcttctgtggtgaaggagccctcgtcattcaccccaggccagggtactcac
ccagttgtggtcgtgcaaccagatgcctggacagaggatgctggcttccgtgtgatcggg
cagatgtgtgaagcacctgtggtaacccgagagtgggtactggacagtgtggccctctac
cattgccaggagctggacacctacctggtcccccaggtcgcccagagctgctgctga
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