KEGG   Muntiacus reevesi (Reeves' muntjac): 136149081
Entry
136149081         CDS       T10466                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree01521  EGFR tyrosine kinase inhibitor resistance
mree01522  Endocrine resistance
mree04010  MAPK signaling pathway
mree04012  ErbB signaling pathway
mree04014  Ras signaling pathway
mree04062  Chemokine signaling pathway
mree04068  FoxO signaling pathway
mree04072  Phospholipase D signaling pathway
mree04150  mTOR signaling pathway
mree04151  PI3K-Akt signaling pathway
mree04380  Osteoclast differentiation
mree04510  Focal adhesion
mree04517  IgSF CAM signaling
mree04540  Gap junction
mree04550  Signaling pathways regulating pluripotency of stem cells
mree04630  JAK-STAT signaling pathway
mree04650  Natural killer cell mediated cytotoxicity
mree04660  T cell receptor signaling pathway
mree04662  B cell receptor signaling pathway
mree04664  Fc epsilon RI signaling pathway
mree04714  Thermogenesis
mree04722  Neurotrophin signaling pathway
mree04910  Insulin signaling pathway
mree04912  GnRH signaling pathway
mree04915  Estrogen signaling pathway
mree04917  Prolactin signaling pathway
mree04926  Relaxin signaling pathway
mree04935  Growth hormone synthesis, secretion and action
mree05034  Alcoholism
mree05160  Hepatitis C
mree05161  Hepatitis B
mree05163  Human cytomegalovirus infection
mree05165  Human papillomavirus infection
mree05200  Pathways in cancer
mree05203  Viral carcinogenesis
mree05205  Proteoglycans in cancer
mree05206  MicroRNAs in cancer
mree05207  Chemical carcinogenesis - receptor activation
mree05208  Chemical carcinogenesis - reactive oxygen species
mree05210  Colorectal cancer
mree05211  Renal cell carcinoma
mree05213  Endometrial cancer
mree05214  Glioma
mree05215  Prostate cancer
mree05220  Chronic myeloid leukemia
mree05221  Acute myeloid leukemia
mree05223  Non-small cell lung cancer
mree05224  Breast cancer
mree05225  Hepatocellular carcinoma
mree05226  Gastric cancer
mree05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mree00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    136149081 (GRB2)
   04012 ErbB signaling pathway
    136149081 (GRB2)
   04014 Ras signaling pathway
    136149081 (GRB2)
   04630 JAK-STAT signaling pathway
    136149081 (GRB2)
   04068 FoxO signaling pathway
    136149081 (GRB2)
   04072 Phospholipase D signaling pathway
    136149081 (GRB2)
   04151 PI3K-Akt signaling pathway
    136149081 (GRB2)
   04150 mTOR signaling pathway
    136149081 (GRB2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    136149081 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    136149081 (GRB2)
   04540 Gap junction
    136149081 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    136149081 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    136149081 (GRB2)
   04660 T cell receptor signaling pathway
    136149081 (GRB2)
   04662 B cell receptor signaling pathway
    136149081 (GRB2)
   04664 Fc epsilon RI signaling pathway
    136149081 (GRB2)
   04062 Chemokine signaling pathway
    136149081 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    136149081 (GRB2)
   04912 GnRH signaling pathway
    136149081 (GRB2)
   04915 Estrogen signaling pathway
    136149081 (GRB2)
   04917 Prolactin signaling pathway
    136149081 (GRB2)
   04926 Relaxin signaling pathway
    136149081 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    136149081 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    136149081 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    136149081 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    136149081 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136149081 (GRB2)
   05206 MicroRNAs in cancer
    136149081 (GRB2)
   05205 Proteoglycans in cancer
    136149081 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    136149081 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    136149081 (GRB2)
   05203 Viral carcinogenesis
    136149081 (GRB2)
   05231 Choline metabolism in cancer
    136149081 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    136149081 (GRB2)
   05225 Hepatocellular carcinoma
    136149081 (GRB2)
   05226 Gastric cancer
    136149081 (GRB2)
   05214 Glioma
    136149081 (GRB2)
   05221 Acute myeloid leukemia
    136149081 (GRB2)
   05220 Chronic myeloid leukemia
    136149081 (GRB2)
   05211 Renal cell carcinoma
    136149081 (GRB2)
   05215 Prostate cancer
    136149081 (GRB2)
   05213 Endometrial cancer
    136149081 (GRB2)
   05224 Breast cancer
    136149081 (GRB2)
   05223 Non-small cell lung cancer
    136149081 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    136149081 (GRB2)
   05160 Hepatitis C
    136149081 (GRB2)
   05163 Human cytomegalovirus infection
    136149081 (GRB2)
   05165 Human papillomavirus infection
    136149081 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    136149081 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    136149081 (GRB2)
   01522 Endocrine resistance
    136149081 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mree04131]
    136149081 (GRB2)
Membrane trafficking [BR:mree04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    136149081 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 SH2_2 DUF5093 DUF7145 hSH3 SH3_4
Other DBs
NCBI-GeneID: 136149081
NCBI-ProteinID: XP_065765065
LinkDB
Position
18:complement(6878473..6944125)
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagccaccgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagag
ctcaatggcaaagacggcttcattcccaagaactacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgctcagcaaacagcggcatgac
ggggcctttcttatccgagagagcgagagtgctcctggggatttctccctctccgtcaag
tttggaaatgatgtacagcacttcaaggtgctccgagatggggctggcaagtatttcctc
tgggtggtcaagttcaactctttgaatgagctggtagattatcacagatctacatccgtc
tccagaaaccagcagatatttctccgggacatagagcaggtgccgcagcagccaacatac
gtccaagccctctttgactttgacccccaagaggatggagagctgggattccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcttgccacggg
cagaccggcatgttcccacgcaattacgtcacccccgtgaaccggaacgtctaa

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