KEGG   Muntiacus reevesi (Reeves' muntjac): 136152603
Entry
136152603         CDS       T10466                                 
Symbol
PIK3R3
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree01521  EGFR tyrosine kinase inhibitor resistance
mree01522  Endocrine resistance
mree01524  Platinum drug resistance
mree04012  ErbB signaling pathway
mree04014  Ras signaling pathway
mree04015  Rap1 signaling pathway
mree04024  cAMP signaling pathway
mree04062  Chemokine signaling pathway
mree04066  HIF-1 signaling pathway
mree04068  FoxO signaling pathway
mree04070  Phosphatidylinositol signaling system
mree04071  Sphingolipid signaling pathway
mree04072  Phospholipase D signaling pathway
mree04081  Hormone signaling
mree04140  Autophagy - animal
mree04145  Phagocytosis
mree04150  mTOR signaling pathway
mree04151  PI3K-Akt signaling pathway
mree04152  AMPK signaling pathway
mree04210  Apoptosis
mree04211  Longevity regulating pathway
mree04213  Longevity regulating pathway - multiple species
mree04218  Cellular senescence
mree04360  Axon guidance
mree04370  VEGF signaling pathway
mree04380  Osteoclast differentiation
mree04510  Focal adhesion
mree04517  IgSF CAM signaling
mree04518  Integrin signaling
mree04550  Signaling pathways regulating pluripotency of stem cells
mree04611  Platelet activation
mree04613  Neutrophil extracellular trap formation
mree04620  Toll-like receptor signaling pathway
mree04625  C-type lectin receptor signaling pathway
mree04630  JAK-STAT signaling pathway
mree04650  Natural killer cell mediated cytotoxicity
mree04660  T cell receptor signaling pathway
mree04662  B cell receptor signaling pathway
mree04664  Fc epsilon RI signaling pathway
mree04666  Fc gamma R-mediated phagosome formation
mree04668  TNF signaling pathway
mree04670  Leukocyte transendothelial migration
mree04722  Neurotrophin signaling pathway
mree04725  Cholinergic synapse
mree04750  Inflammatory mediator regulation of TRP channels
mree04810  Regulation of actin cytoskeleton
mree04910  Insulin signaling pathway
mree04914  Progesterone-mediated oocyte maturation
mree04915  Estrogen signaling pathway
mree04917  Prolactin signaling pathway
mree04919  Thyroid hormone signaling pathway
mree04923  Regulation of lipolysis in adipocytes
mree04926  Relaxin signaling pathway
mree04929  GnRH secretion
mree04930  Type II diabetes mellitus
mree04931  Insulin resistance
mree04932  Non-alcoholic fatty liver disease
mree04933  AGE-RAGE signaling pathway in diabetic complications
mree04935  Growth hormone synthesis, secretion and action
mree04960  Aldosterone-regulated sodium reabsorption
mree04973  Carbohydrate digestion and absorption
mree05010  Alzheimer disease
mree05017  Spinocerebellar ataxia
mree05020  Prion disease
mree05100  Bacterial invasion of epithelial cells
mree05135  Yersinia infection
mree05142  Chagas disease
mree05146  Amoebiasis
mree05160  Hepatitis C
mree05161  Hepatitis B
mree05162  Measles
mree05163  Human cytomegalovirus infection
mree05164  Influenza A
mree05165  Human papillomavirus infection
mree05166  Human T-cell leukemia virus 1 infection
mree05167  Kaposi sarcoma-associated herpesvirus infection
mree05168  Herpes simplex virus 1 infection
mree05169  Epstein-Barr virus infection
mree05170  Human immunodeficiency virus 1 infection
mree05171  Coronavirus disease
mree05200  Pathways in cancer
mree05203  Viral carcinogenesis
mree05205  Proteoglycans in cancer
mree05206  MicroRNAs in cancer
mree05207  Chemical carcinogenesis - receptor activation
mree05208  Chemical carcinogenesis - reactive oxygen species
mree05210  Colorectal cancer
mree05211  Renal cell carcinoma
mree05212  Pancreatic cancer
mree05213  Endometrial cancer
mree05214  Glioma
mree05215  Prostate cancer
mree05218  Melanoma
mree05220  Chronic myeloid leukemia
mree05221  Acute myeloid leukemia
mree05222  Small cell lung cancer
mree05223  Non-small cell lung cancer
mree05224  Breast cancer
mree05225  Hepatocellular carcinoma
mree05226  Gastric cancer
mree05230  Central carbon metabolism in cancer
mree05231  Choline metabolism in cancer
mree05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mree05415  Diabetic cardiomyopathy
mree05417  Lipid and atherosclerosis
mree05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mree00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    136152603 (PIK3R3)
   04014 Ras signaling pathway
    136152603 (PIK3R3)
   04015 Rap1 signaling pathway
    136152603 (PIK3R3)
   04370 VEGF signaling pathway
    136152603 (PIK3R3)
   04630 JAK-STAT signaling pathway
    136152603 (PIK3R3)
   04668 TNF signaling pathway
    136152603 (PIK3R3)
   04066 HIF-1 signaling pathway
    136152603 (PIK3R3)
   04068 FoxO signaling pathway
    136152603 (PIK3R3)
   04070 Phosphatidylinositol signaling system
    136152603 (PIK3R3)
   04072 Phospholipase D signaling pathway
    136152603 (PIK3R3)
   04071 Sphingolipid signaling pathway
    136152603 (PIK3R3)
   04024 cAMP signaling pathway
    136152603 (PIK3R3)
   04151 PI3K-Akt signaling pathway
    136152603 (PIK3R3)
   04152 AMPK signaling pathway
    136152603 (PIK3R3)
   04150 mTOR signaling pathway
    136152603 (PIK3R3)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    136152603 (PIK3R3)
   04517 IgSF CAM signaling
    136152603 (PIK3R3)
   04518 Integrin signaling
    136152603 (PIK3R3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    136152603 (PIK3R3)
   04140 Autophagy - animal
    136152603 (PIK3R3)
  09143 Cell growth and death
   04210 Apoptosis
    136152603 (PIK3R3)
   04218 Cellular senescence
    136152603 (PIK3R3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    136152603 (PIK3R3)
   04550 Signaling pathways regulating pluripotency of stem cells
    136152603 (PIK3R3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    136152603 (PIK3R3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    136152603 (PIK3R3)
   04613 Neutrophil extracellular trap formation
    136152603 (PIK3R3)
   04620 Toll-like receptor signaling pathway
    136152603 (PIK3R3)
   04625 C-type lectin receptor signaling pathway
    136152603 (PIK3R3)
   04650 Natural killer cell mediated cytotoxicity
    136152603 (PIK3R3)
   04660 T cell receptor signaling pathway
    136152603 (PIK3R3)
   04662 B cell receptor signaling pathway
    136152603 (PIK3R3)
   04664 Fc epsilon RI signaling pathway
    136152603 (PIK3R3)
   04666 Fc gamma R-mediated phagosome formation
    136152603 (PIK3R3)
   04670 Leukocyte transendothelial migration
    136152603 (PIK3R3)
   04062 Chemokine signaling pathway
    136152603 (PIK3R3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    136152603 (PIK3R3)
   04923 Regulation of lipolysis in adipocytes
    136152603 (PIK3R3)
   04929 GnRH secretion
    136152603 (PIK3R3)
   04915 Estrogen signaling pathway
    136152603 (PIK3R3)
   04914 Progesterone-mediated oocyte maturation
    136152603 (PIK3R3)
   04917 Prolactin signaling pathway
    136152603 (PIK3R3)
   04926 Relaxin signaling pathway
    136152603 (PIK3R3)
   04935 Growth hormone synthesis, secretion and action
    136152603 (PIK3R3)
   04919 Thyroid hormone signaling pathway
    136152603 (PIK3R3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    136152603 (PIK3R3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    136152603 (PIK3R3)
  09156 Nervous system
   04725 Cholinergic synapse
    136152603 (PIK3R3)
   04722 Neurotrophin signaling pathway
    136152603 (PIK3R3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    136152603 (PIK3R3)
  09158 Development and regeneration
   04360 Axon guidance
    136152603 (PIK3R3)
   04380 Osteoclast differentiation
    136152603 (PIK3R3)
  09149 Aging
   04211 Longevity regulating pathway
    136152603 (PIK3R3)
   04213 Longevity regulating pathway - multiple species
    136152603 (PIK3R3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136152603 (PIK3R3)
   05206 MicroRNAs in cancer
    136152603 (PIK3R3)
   05205 Proteoglycans in cancer
    136152603 (PIK3R3)
   05207 Chemical carcinogenesis - receptor activation
    136152603 (PIK3R3)
   05208 Chemical carcinogenesis - reactive oxygen species
    136152603 (PIK3R3)
   05203 Viral carcinogenesis
    136152603 (PIK3R3)
   05230 Central carbon metabolism in cancer
    136152603 (PIK3R3)
   05231 Choline metabolism in cancer
    136152603 (PIK3R3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    136152603 (PIK3R3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    136152603 (PIK3R3)
   05212 Pancreatic cancer
    136152603 (PIK3R3)
   05225 Hepatocellular carcinoma
    136152603 (PIK3R3)
   05226 Gastric cancer
    136152603 (PIK3R3)
   05214 Glioma
    136152603 (PIK3R3)
   05221 Acute myeloid leukemia
    136152603 (PIK3R3)
   05220 Chronic myeloid leukemia
    136152603 (PIK3R3)
   05218 Melanoma
    136152603 (PIK3R3)
   05211 Renal cell carcinoma
    136152603 (PIK3R3)
   05215 Prostate cancer
    136152603 (PIK3R3)
   05213 Endometrial cancer
    136152603 (PIK3R3)
   05224 Breast cancer
    136152603 (PIK3R3)
   05222 Small cell lung cancer
    136152603 (PIK3R3)
   05223 Non-small cell lung cancer
    136152603 (PIK3R3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    136152603 (PIK3R3)
   05170 Human immunodeficiency virus 1 infection
    136152603 (PIK3R3)
   05161 Hepatitis B
    136152603 (PIK3R3)
   05160 Hepatitis C
    136152603 (PIK3R3)
   05171 Coronavirus disease
    136152603 (PIK3R3)
   05164 Influenza A
    136152603 (PIK3R3)
   05162 Measles
    136152603 (PIK3R3)
   05168 Herpes simplex virus 1 infection
    136152603 (PIK3R3)
   05163 Human cytomegalovirus infection
    136152603 (PIK3R3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136152603 (PIK3R3)
   05169 Epstein-Barr virus infection
    136152603 (PIK3R3)
   05165 Human papillomavirus infection
    136152603 (PIK3R3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    136152603 (PIK3R3)
   05100 Bacterial invasion of epithelial cells
    136152603 (PIK3R3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    136152603 (PIK3R3)
   05142 Chagas disease
    136152603 (PIK3R3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    136152603 (PIK3R3)
   05017 Spinocerebellar ataxia
    136152603 (PIK3R3)
   05020 Prion disease
    136152603 (PIK3R3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136152603 (PIK3R3)
   05418 Fluid shear stress and atherosclerosis
    136152603 (PIK3R3)
   05415 Diabetic cardiomyopathy
    136152603 (PIK3R3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    136152603 (PIK3R3)
   04932 Non-alcoholic fatty liver disease
    136152603 (PIK3R3)
   04931 Insulin resistance
    136152603 (PIK3R3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    136152603 (PIK3R3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    136152603 (PIK3R3)
   01524 Platinum drug resistance
    136152603 (PIK3R3)
   01522 Endocrine resistance
    136152603 (PIK3R3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mree04131]
    136152603 (PIK3R3)
Membrane trafficking [BR:mree04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    136152603 (PIK3R3)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 SH2_1 DicA_C ODF2_C Exonuc_VII_L
Other DBs
NCBI-GeneID: 136152603
NCBI-ProteinID: XP_065769937
LinkDB
Position
1:158774006..158871983
AA seq 484 aa
MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPVEETFEYRIFYIKESSRTHQKGFTL
PPKPPKPMTSAITNGIKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQ
GDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELISHYHHESLAQYNPKLDVKLM
YPVSRYQQDQLVKEDNIDAVGKKLQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIE
AFNETIKIFEEQCHTQEQHSKEYIERFRKEGNEKEIERIMMNYDKLKSRLGEIHDSKMRL
EQDLKKQALDNREIDKKMNSIKPDLIQLRKIRDQHLVWLNHKGVRQKRLNAWLGIKNEDA
DETYFINEEDENLPHYDEKTWFVEDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVA
DGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMP
SLCR
NT seq 1455 nt   +upstreamnt  +downstreamnt
atgtacaatacggtgtggagtatggaccgcgatgacgcagactggagggaggtgatgatg
ccctattcgacagaactgatattttatattgaaatggatcctccagtggaagaaacattt
gaatatagaatattttacattaaggaatcttcaagaacacatcagaaaggatttactctt
ccaccaaagccacctaagccaatgacttcagccattacaaatggaataaaggacagttct
gtttctcttcaggatgcagaatggtactggggggatatttcaagggaggaggtaaatgac
aaattacgggacatgccagatggtaccttcttggtcagagatgcctcaaccaaaatgcag
ggagattacactttgaccttgcggaagggaggcaataataagctaataaagatctatcat
cgagatggtaaatatggcttttctgatcctctgacatttaattctgtggtggagctcatt
agccactatcatcatgaatctcttgcccagtacaatcccaaacttgatgtgaaactgatg
tacccagtgtccagataccaacaggatcagttggtaaaagaagataatattgatgccgtc
ggtaaaaaactgcaggagtatcactctcagtatcaggaaaagagtaaagaatatgacaga
ctatatgaagaatataccagaacatcccaggaaatacagatgaagaggactgcaattgaa
gcttttaatgaaacaattaaaatatttgaagagcagtgtcatacacaagaacagcatagc
aaagaatatattgagcgatttcgaaaagaagggaatgaaaaggaaattgaacgaattatg
atgaattatgacaagttgaaatcacgtctgggtgagattcatgatagcaaaatgcgtctt
gaacaggatttgaagaaacaagctttggataaccgagaaatagataaaaaaatgaatagt
atcaaacctgacctgatccagctgcgcaagatccgagatcagcaccttgtgtggctcaat
cacaaaggagtgagacagaagcgcctgaatgcctggctggggatcaagaatgaggatgct
gatgagacctattttatcaatgaggaagatgaaaacctgccccattatgatgagaaaacc
tggtttgttgaggatatcaaccgagtacaagctgaggacttgctttatgggaaacctgac
ggtgcattcttaatccgtgagagtagcaagaaaggatgttatgcttgctctgtggtcgcc
gatggagaggtgaagcactgcgtgatctacagcactgctcggggctacggcttcgcagag
ccctacaacctgtacagctccctgaaggagctggtgctgcactaccagcagacgtccctg
gtgcagcacaacgactctctcaacgtcaggctcgcctaccctgtccacgcacagatgccc
tcgctctgcagataa

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