KEGG   Muntiacus reevesi (Reeves' muntjac): 136152846
Entry
136152846         CDS       T10466                                 
Symbol
FGFR3
Name
(RefSeq) fibroblast growth factor receptor 3 isoform X1
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree01521  EGFR tyrosine kinase inhibitor resistance
mree04010  MAPK signaling pathway
mree04014  Ras signaling pathway
mree04015  Rap1 signaling pathway
mree04020  Calcium signaling pathway
mree04144  Endocytosis
mree04151  PI3K-Akt signaling pathway
mree04550  Signaling pathways regulating pluripotency of stem cells
mree04810  Regulation of actin cytoskeleton
mree05200  Pathways in cancer
mree05206  MicroRNAs in cancer
mree05219  Bladder cancer
mree05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mree00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    136152846 (FGFR3)
   04014 Ras signaling pathway
    136152846 (FGFR3)
   04015 Rap1 signaling pathway
    136152846 (FGFR3)
   04020 Calcium signaling pathway
    136152846 (FGFR3)
   04151 PI3K-Akt signaling pathway
    136152846 (FGFR3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    136152846 (FGFR3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    136152846 (FGFR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    136152846 (FGFR3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136152846 (FGFR3)
   05206 MicroRNAs in cancer
    136152846 (FGFR3)
   05230 Central carbon metabolism in cancer
    136152846 (FGFR3)
  09162 Cancer: specific types
   05219 Bladder cancer
    136152846 (FGFR3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    136152846 (FGFR3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mree01001]
    136152846 (FGFR3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:mree04090]
    136152846 (FGFR3)
Enzymes [BR:mree01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     136152846 (FGFR3)
Protein kinases [BR:mree01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   136152846 (FGFR3)
CD molecules [BR:mree04090]
 Proteins
  136152846 (FGFR3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set FGFR3_TM C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 136152846
NCBI-ProteinID: XP_065770374
LinkDB
Position
22:926958..943569
AA seq 804 aa
MSAPARVLAFCVAVAVMTGAVLGSPGVEPRVARRAAEVPGPEPSPQERAFGSGDTVELSC
RLPAGAPTEPTIWVKDGVGLAPSDRVLVGPQRLQVLNASHEDAGAYSCRQRLSQRVLCLF
NVRVTDAPSSGDDEDEDDEAEDTAGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTP
SITWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGRIQQTYTLD
VLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTP
YVTVLKTAGANTTDKELEVLSLRNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELV
EAGEAGSVFAGVLSYGLGFLLFILAVAAVTLYRLRSPPKKGLGSPAVHKVSRFPLKRQVT
VSLESSSSMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGC
FGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLL
GACTQGGPLYVLVEYAAKGNLREYLRARRPPGTDYSFDTCRLPEEQLTFKDLVSCAYQVA
RGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMA
PEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHD
LYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSVPFEQYSPGGQDTPSSGS
SGDDSVFAHDLLPAAPPGSGGSRT
NT seq 2415 nt   +upstreamnt  +downstreamnt
atgagcgctccggctcgcgtcctcgcgttttgcgtggcagtggcggtcatgaccggcgcc
gtcctcggttccccgggcgtggagccccgcgtcgcgcggagagcggcagaggtcccaggc
cccgagcccagcccgcaggagcgggcctttggcagtggggacaccgtggagctgagctgc
cgcttgccggcgggggcacccacggagcccaccatctgggtgaaggacggtgtgggcctg
gcgccctcggaccgcgtcctggtggggccgcagcggctacaggtgctcaacgcctcccac
gaggatgccggggcctacagctgccgccagcgcctctcccagcgggtgctgtgcctcttc
aacgtgcgcgtgacagacgccccgtcctcgggggacgacgaagatgaggacgacgaggcc
gaggacacagcgggggccccttactggacgcggcccgagcggatggacaagaagctgctg
gcggtgccggccgccaacactgttcgcttccgctgcccggctgccggcaaccccacgccg
tccatcacctggctgaagaacggcaaggagttccggggcgagcaccgcatcgggggcatc
aagctgcggcaccagcagtggagcctggtcatggagagcgtggtgccctcggaccgcggc
aactacacgtgcgtcgtggagaacaagttcggcagaatccagcagacctacaccctggac
gtgctggagcgctctccgcaccgccccatcctacaggcggggctgcccgccaaccagacc
gccgtgctgggcagcgacgtggagttccactgcaaggtctacagtgacgcccagccccac
atccagtggctgaagcacgtggaggtgaacggcagcaaggtggggcccgacggcacgccc
tacgtcaccgtgctcaagacggcgggcgctaacaccaccgacaaggagctagaggttcta
tccttgcgcaatgtcacctttgaggacgcgggggagtacacgtgtctggcgggcaattct
atcgggttttcccatcactctgcgtggctggtggtgctgccagccgaggaggagctggtg
gaggccggtgaggctggcagtgtgtttgcgggcgtcctcagctacgggctgggcttcctc
ctcttcatcctagccgtggccgccgtgacgctctaccgcctgaggagcccacccaagaag
ggcctgggctcgcccgcagtgcacaaggtctcccgcttcccgctcaagcgacaggtaaca
gtgtccttggagtccagttcgtctatgagctccaacacgccgctggtgcgcatcgcccgg
ctgtcctcgggcgagggccccaccctggccaacgtctctgagctcgagctgcccgccgac
cccaagtgggagctgtcccgggcccggctgaccctgggcaagcctctcggggagggctgc
ttcggccaggtggtcatggcagaggccattggcatcgacaaggaccgagctgccaagccc
gtcacggtggcggtgaagatgctgaaagatgacgccacggataaggacttatcggacctg
gtgtccgagatggagatgatgaagatgatcggaaaacacaagaacattatcaacctgctg
ggcgcctgcacgcagggcgggcccctgtacgtgctggtggagtacgcggccaagggcaac
ctgcgggaatacctaagggcgcggcggcccccgggcactgactactccttcgacacctgc
cggctgcccgaggagcagctcaccttcaaagacctggtgtcctgcgcctaccaggtggcg
cggggcatggagtacctggcctcgcagaagtgcatccatagggacctggcggcccgcaac
gtgctggtgaccgaggacaacgtgatgaaaatcgccgacttcggcctggcccgtgacgtg
cacaacctcgactactacaagaagaccaccaacggccgcctgcccgtgaagtggatggca
cccgaggccttgtttgaccgcgtctacacccaccaaagtgacgtctggtccttcggggtc
ctgctctgggagattttcacgctggggggctcgccgtaccccggcatccccgtggaggag
ctcttcaagctgctgaaggaaggccaccgcatggacaagccggccaactgcacgcatgat
ctgtacatgatcatgcgtgagtgctggcacgccgcgccctcgcagaggcccactttcaag
cagctggtggaggacctggaccgcgtgctcaccgtgacgtccaccgacgagtacctggac
ctgtcagtgcccttcgagcagtactcgccaggcggccaggacacccccagctccggctcc
tcgggagacgactccgtgttcgctcacgacctgctgcccgcggccccacccggcagcggg
ggctcgcggacgtga

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