KEGG   Muntiacus reevesi (Reeves' muntjac): 136164999
Entry
136164999         CDS       T10466                                 
Symbol
CASP8
Name
(RefSeq) caspase-8
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree01524  Platinum drug resistance
mree04115  p53 signaling pathway
mree04210  Apoptosis
mree04215  Apoptosis - multiple species
mree04217  Necroptosis
mree04620  Toll-like receptor signaling pathway
mree04621  NOD-like receptor signaling pathway
mree04622  RIG-I-like receptor signaling pathway
mree04623  Cytosolic DNA-sensing pathway
mree04625  C-type lectin receptor signaling pathway
mree04657  IL-17 signaling pathway
mree04668  TNF signaling pathway
mree04932  Non-alcoholic fatty liver disease
mree04936  Alcoholic liver disease
mree05010  Alzheimer disease
mree05016  Huntington disease
mree05022  Pathways of neurodegeneration - multiple diseases
mree05132  Salmonella infection
mree05134  Legionellosis
mree05142  Chagas disease
mree05145  Toxoplasmosis
mree05152  Tuberculosis
mree05160  Hepatitis C
mree05161  Hepatitis B
mree05162  Measles
mree05163  Human cytomegalovirus infection
mree05164  Influenza A
mree05165  Human papillomavirus infection
mree05167  Kaposi sarcoma-associated herpesvirus infection
mree05168  Herpes simplex virus 1 infection
mree05169  Epstein-Barr virus infection
mree05170  Human immunodeficiency virus 1 infection
mree05200  Pathways in cancer
mree05203  Viral carcinogenesis
mree05416  Viral myocarditis
mree05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mree00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    136164999 (CASP8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    136164999 (CASP8)
   04215 Apoptosis - multiple species
    136164999 (CASP8)
   04217 Necroptosis
    136164999 (CASP8)
   04115 p53 signaling pathway
    136164999 (CASP8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    136164999 (CASP8)
   04621 NOD-like receptor signaling pathway
    136164999 (CASP8)
   04622 RIG-I-like receptor signaling pathway
    136164999 (CASP8)
   04623 Cytosolic DNA-sensing pathway
    136164999 (CASP8)
   04625 C-type lectin receptor signaling pathway
    136164999 (CASP8)
   04657 IL-17 signaling pathway
    136164999 (CASP8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136164999 (CASP8)
   05203 Viral carcinogenesis
    136164999 (CASP8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    136164999 (CASP8)
   05161 Hepatitis B
    136164999 (CASP8)
   05160 Hepatitis C
    136164999 (CASP8)
   05164 Influenza A
    136164999 (CASP8)
   05162 Measles
    136164999 (CASP8)
   05168 Herpes simplex virus 1 infection
    136164999 (CASP8)
   05163 Human cytomegalovirus infection
    136164999 (CASP8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136164999 (CASP8)
   05169 Epstein-Barr virus infection
    136164999 (CASP8)
   05165 Human papillomavirus infection
    136164999 (CASP8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    136164999 (CASP8)
   05134 Legionellosis
    136164999 (CASP8)
   05152 Tuberculosis
    136164999 (CASP8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    136164999 (CASP8)
   05142 Chagas disease
    136164999 (CASP8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    136164999 (CASP8)
   05016 Huntington disease
    136164999 (CASP8)
   05022 Pathways of neurodegeneration - multiple diseases
    136164999 (CASP8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136164999 (CASP8)
   05416 Viral myocarditis
    136164999 (CASP8)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    136164999 (CASP8)
   04932 Non-alcoholic fatty liver disease
    136164999 (CASP8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    136164999 (CASP8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mree01002]
    136164999 (CASP8)
Enzymes [BR:mree01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     136164999 (CASP8)
Peptidases and inhibitors [BR:mree01002]
 Cysteine peptidases
  Family C14: caspase family
   136164999 (CASP8)
SSDB
Motif
Pfam: Peptidase_C14 DED PYRIN
Other DBs
NCBI-GeneID: 136164999
NCBI-ProteinID: XP_065786902
LinkDB
Position
3:complement(145970404..145993916)
AA seq 488 aa
MDLTQCLYKIGEELGSDDLAALKFLSRDHIPYRKQEPINDAWMLFQRLQERRMLEESNLS
FLKELLFRVNRLDLLRYYLDTSEEEMKRELHIPGRAQISAYRILLFQISEDVNKVELKEF
KFFLSQEIAKCKLDDDMTLLDIFVEMEKRTILGEENLDTLKRICEQVNKSLLKKIIDYEE
LRKDSERRMSLERDPDEFSNDTSQPLPEEGSSEMLAMSDSPGEQDSELQTSDTAYRMTSK
PRGYCLIINNYDFSIARRKVPELQKLKNRSGTHFDAEALDKTFRELHFEIVHYKDQTAKE
IHKILEFYQKKDHKNRDCFICCILSHGNQGIVYGTDGQEAPIYELTSYFTGLKCPSLVGK
PKIFFIQACQGDDYQRGIAVETDSEQMEVCLEVDSAPRRRYIPNEADFLLGMATVNKCVS
YRSIREGTWYIQSLCQNLRKRCPRGEDILTILTKVNFEVSNKDDKRNMGKQMPQPTFTLR
KKLFFPLN
NT seq 1467 nt   +upstreamnt  +downstreamnt
atggatctcacccaatgtctctataaaattggggaagagctgggcagtgacgacctggct
gccctcaagttcctaagccgggaccacatcccgtataggaagcaggaacccatcaacgat
gcctggatgctattccagaggctccaagaaaggagaatgttggaggaaagcaatctgtcc
ttcttgaaggagctgcttttccgagtgaatagactggatctgctgcgttactacttggac
accagcgaggaggagatgaagagggagcttcacatacccggcagggcccagatctctgcc
tacaggatcctgcttttccagatttcagaagatgtgaacaaagtggaattgaaggagttt
aagttttttttgagccaggagattgccaaatgtaagctggatgatgacatgactttgctt
gatattttcgtggagatggagaagaggaccatcctaggggaagaaaacttggacaccctg
aaaagaatctgtgagcaggtcaacaagagcctgctgaagaaaatcattgattatgaagaa
ttaagaaaagattcagagagaagaatgagccttgaaagagatccagatgaattttcaaat
gatacgtcacaaccgcttccagaggagggctcctctgagatgctggccatgtcagactct
ccaggagaacaggacagtgagttgcagacatccgacacagcttaccgaatgacaagcaaa
cctcgggggtactgtttgatcattaacaattatgattttagcatagcacggaggaaggtg
cccgaacttcagaaactaaagaataggagtggaacacacttcgacgcagaggctttggac
aagacctttagggaacttcattttgagatagtgcactacaaagaccaaacagcaaaggaa
atccataagattctggaattctaccagaagaaggaccacaaaaacagagactgcttcatc
tgctgcatcctctcccatggaaaccagggcatcgtctatggcaccgatgggcaagaagcc
cccatctatgagctgacctcttacttcactggcttaaaatgcccttcccttgttggcaaa
cccaaaatcttttttattcaggcttgtcaaggggatgactaccagagaggtatagctgtt
gagaccgactcagaacagatggaagtctgtttagaagtggattcagcacctcggaggaga
tatatcccaaatgaggctgactttctgctggggatggccactgtgaacaaatgtgtctcc
taccgaagcatcagggaggggacctggtatatccaatcgctttgccagaacctgagaaaa
agatgtcctaggggtgaagacattctcaccatcctaaccaaggtgaacttcgaagtaagc
aataaggatgacaagagaaatatgggcaaacagatgccacaacctactttcacactgcga
aaaaaactcttctttcctcttaattga

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