Muntiacus reevesi (Reeves' muntjac): 136173790
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Entry
136173790 CDS
T10466
Symbol
BACE2
Name
(RefSeq) beta-secretase 2 isoform X1
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
mree Muntiacus reevesi (Reeves' muntjac)
Pathway
mree05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
mree00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
136173790 (BACE2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mree01002
]
136173790 (BACE2)
Enzymes [BR:
mree01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
136173790 (BACE2)
Peptidases and inhibitors [BR:
mree01002
]
Aspartic peptidases
Family A1: pepsin family
136173790 (BACE2)
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Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
136173790
NCBI-ProteinID:
XP_065799788
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Position
8:21162719..21268346
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AA seq
514 aa
AA seq
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MGALARALLLPLLAQWLLRAAPALASAPFTLPLRVASTTSRGAVPTPGPGPPAEPRADGL
ALALEPAGSAANFLAMVDNLQGDSGRGYYLEMQIGTPPQKLQILVDTGSSNFAVAGAPHP
YIDSYFDSERSSTYRPKGFDVTVKYTQGSWTGFVGEDVVTIPKGFNSSFLVNIATIFESE
NFFLPGIRWNGILGLAYATLAKPSSSLETFFDSLVAQAKIPNVFSMQMCGAGLPVAGSGT
NGGSLVLGGIEPTLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEAVARTSLIPEFSEGFWTGSQLACWTNSETPWSYFPKISIYLRD
ENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVVFDRARK
RVGFAASPCAEIAGAPVSEISGPFSTEDIASNCVPALPLNEPILWIVSYTLMSVCGVILL
VLITLLLLPVRCRHHPRDPEVVNDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgctggcccgggcgctgctgctgccgctgctggctcagtggctcctgcgagcg
gccccggcgctggcctccgcgcccttcacgctgcctctccgggtggcctcgaccaccagc
cggggggctgtgcctaccccgggacccggaccccccgctgagccccgcgcggacggcctg
gcgctcgccctggaacccgctgggagtgcggccaacttcttggccatggtggataacctg
cagggggactccggccgcggctactacctggagatgcagatcgggacccccccgcagaag
ctgcagatactcgttgacaccggaagcagcaactttgccgtggctggggccccacatccc
tatatcgactcttactttgactcagagaggtccagcacgtaccgccccaagggttttgat
gtcactgtgaagtacacgcaggggagctggaccggcttcgttggggaggatgtggttacc
atccccaaaggcttcaacagttcttttcttgtcaacatcgccaccatatttgagtcggag
aatttctttctgcctgggattagatggaatggaatacttggactggcttatgctacgctg
gccaagccttcaagttctctggagaccttctttgattccctcgtggcacaagcaaaaatc
cccaacgtgttctccatgcagatgtgtggagccggactgccagtagctggatctggtacc
aacggaggtagtcttgtcctaggtggaattgaaccaactttgtacaaaggagacatctgg
tacacccctattaaggaagagtggtattatcagatagaaattctaaaattggaaattgga
ggccagagccttaatctggactgcagagagtacaatgcggacaaggccatcgtggacagt
ggcaccacgctgctgcgcctgccccagaaggtgtttgacgccgtggtggaggctgtggcc
cgcacatctctgattccagaattctctgaaggtttctggactggttcccagctggcatgc
tggacgaattctgaaacaccttggtcttatttcccgaaaatctccatctacctgagagac
gagaactccagcagatcattccgtataactatcctgcctcagctttacattcagcccatg
atgggggctggcctgaattatgaatgttaccggttcggcatctcgccttccaccaacgca
ctggtgattggtgctaccgtcatggagggcttctacgtggtctttgacagagctcggaag
agagtgggctttgcggccagcccctgtgcagagatcgcaggtgctccggtgtctgagatt
tccgggcctttctcaacagaggacatagccagcaactgcgtccctgccctgccgttgaac
gagcccattttgtggatcgtctcctatactctcatgagcgtgtgtggagtcatccttctt
gttttaatcaccctgctgctacttccggtccggtgtaggcatcacccccgagatcccgag
gtggtcaacgatgagtcctcgctcgtccggcatcgctggaaatga
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