Mycolicibacterium rufum: MJO55_15935
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Entry
MJO55_15935 CDS
T08167
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
mrf
Mycolicibacterium rufum
Pathway
mrf00270
Cysteine and methionine metabolism
mrf00450
Selenocompound metabolism
mrf00670
One carbon pool by folate
mrf01100
Metabolic pathways
mrf01110
Biosynthesis of secondary metabolites
mrf01230
Biosynthesis of amino acids
mrf04980
Cobalamin transport and metabolism
mrf04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
mrf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
MJO55_15935 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
MJO55_15935 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
MJO55_15935 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
MJO55_15935 (metH)
04980 Cobalamin transport and metabolism
MJO55_15935 (metH)
Enzymes [BR:
mrf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
MJO55_15935 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
CdhD
Motif
Other DBs
NCBI-ProteinID:
ULP34821
LinkDB
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Position
5410162..5413926
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AA seq
1254 aa
AA seq
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MEGTHVDTPETDSFAPNIRPDCTDALAAALRERILVIDGAMGTAIQRDRPDEAGYRGERF
ADWPSDLVGNNDLLTLTQPHIIAAIHREYLEAGADILETNTFNANAVSLSDYGMEEFAYE
LNYAGAALARAACDEFSTPDKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLVAAYA
DAARGLIDGGADLLIVETIFDTLNAKAAIFAIESLFEDRGRRWPVIVSGTITDASGRTLS
GQVTEAFWNSIRHAKPLAVGLNCALGAPEMRPYLAEMSRIADTFVSCYPNAGLPNAFGEY
DESPKRQAGYVADFAEAGLVNMVGGCCGTTPAHIAEIAKVVEGKAPREVPEIPLATRLSG
LEPLNITSDSLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMDE
GMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKFEVIEAGLKNVQGKPIVNSISMKEGEE
KFVREARLCRKYGAAVVVMAFDEQGQADNLERRKEICGRAYRILTEEVGFPAEDIVFDPN
CFALATGIEEHATYGIDFIDACAWIKENLPAVHISGGISNVSFSFRGNNPVREAIHSVFL
FHAIKAGLDMGIVNAGALVPYDSIDPELKERIEDVVLNRREDAAERLLEIAERFNKSEKT
EDPAAAEWRSLPVRERITHALVKGIDAHVDDDTEELRAEIASAGGRPIEVIEGPLMDGMN
VVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPYIEAEKAENGTSAAKDTNGTIIMATVKG
DVHDIGKNIVGVVLQCNNFEVIDLGVMVPAQKILDAAKEHDADIIGLSGLITPSLDEMVN
FAVEMERQGLEIPLLIGGATTSRAHTAVKISPRRSGPVVWVKDASRSVPVAAALLDDKQR
PALLEATEKDYASLRERHAQKNERPMLTLEKARANRTPIVWDDYTPPVPAQGLGVREFSD
YDLAELREYIDWQPFFNAWELKGRFPDILNNPASGETARKLYDDAQEMLDTLIKEKWLTA
NGVIGFFPANAVGDDIEVYTDESRTEVLTTLRNLRQQGEHREGIPNRSLGDFVAPKDTGL
ADYVGAFAVTAGLGSAEKIIEFKAAHDDYNAILLESLADRLAEAFAERMHQRVRTEFWGY
QPEEHLDNDALIGEKYVGIRPAPGYPACPEHTEKSTLWELMDVTTRTGIELTESMAMWPG
AAVSGWYFSHPQSQYFVVGRLAQDQVADYAKRKGWTLAEAERWLAPNLGYNPED
NT seq
3765 nt
NT seq
+upstream
nt +downstream
nt
atggaaggaacgcacgtggacactcctgagacggactccttcgcgccgaacatccgtccc
gactgcaccgacgcgctggcggccgcgctgcgcgagcggatcctggtgatcgacggcgcc
atgggaacggcgatccagcgcgaccgccccgacgaggccggctaccgcggcgagcggttc
gccgactggcccagcgacctggtcggcaacaacgacctgctcaccctgacgcagccgcac
atcatcgccgcgatccaccgcgagtacctggaggccggcgccgacatcctggagaccaac
acgttcaacgcgaacgcggtctcgctgtccgactacggcatggaggagttcgcctacgaa
ctcaactacgcgggcgcggccctggcccgggcggcctgcgacgagttcagcacccccgac
aagccgcgctacgtcgccggggccctcgggccgacgacgcgcaccgcgtcgatctccccg
gacgtcaacgaccccggcgcccgcaacgtctcctacgaccagctggtcgccgcctacgcc
gacgccgcccgcggcctcatcgacggcggcgccgacctgctgatcgtcgagaccatcttc
gacacgctgaacgccaaggccgcgatcttcgcgatcgagtcgctgttcgaggaccgcgga
cgccgctggccggtcatcgtctcgggcaccatcaccgacgcctccgggcggacgctgtcg
ggtcaggtcaccgaggcgttctggaactcgatccggcacgccaagccgctcgcggtcggc
ctcaactgcgcgctgggcgcaccggagatgcggccctacctggccgagatgtcccgcatc
gccgacaccttcgtgtcgtgctacccgaatgccgggctgcccaacgcattcggcgagtac
gacgagtcgccgaagcgtcaggccgggtacgtcgccgacttcgccgaggccggcctggtc
aacatggtcggcggctgctgtggcaccacgccggcgcacatcgccgagatcgcgaaggtc
gtcgagggcaaggcgccgcgcgaggtgccggagatccccttggccacccgcctgtcgggc
ctggagccgctgaacatcacctccgactcgctgttcgtgaacatcggtgagcgcaccaac
atcaccggatcggcgcggttccgcaacctcatcaaggccgaggactacgacaccgcgctg
tcggtggcgttgcagcaggtcgaggtcggggcacaggtcatcgacatcaacatggacgag
gggatgatcgacggcgtcgccgcgatggaccgcttcactaagctgatcgccgccgagccg
gacatcagccgtgtcccggtgatgatcgactcctccaagttcgaggtcatcgaggccggc
ctgaagaacgtgcagggcaagccgatcgtcaactccatctcgatgaaggagggcgaggag
aagttcgtccgcgaggcgcggctgtgccgcaagtacggcgccgccgtcgtcgtgatggcc
ttcgacgagcaggggcaggccgacaacctggagcggcgcaaggagatctgcggacgcgcc
taccggatcctcaccgaggaggtcggcttcccggccgaggacatcgtcttcgacccgaac
tgcttcgcgctggccacgggcatcgaggagcacgccacctacggcatcgacttcatcgac
gcgtgcgcgtggatcaaggagaacctgcccgcggtgcacatctccggcggcatctccaac
gtgtcgttctcgttccgcggcaacaaccccgtccgcgaggcgatccactcggtgttcctg
ttccacgccatcaaggccggcctggacatgggcatcgtcaacgccggcgcgctggtgccc
tacgactcgatcgaccccgagctcaaggagcgcatcgaggacgtcgtgctgaaccgacgc
gaggatgcggccgaacgcctgctggagatcgccgaacggttcaacaagtccgagaagacg
gaggatccggccgcagcggagtggcggtccctgccggtccgtgagcggatcacccacgcg
ctggtcaagggcatcgacgcgcacgtcgacgacgacaccgaggaactgcgcgccgagatc
gcctcggccggtggccggcccatcgaggtcatcgagggaccgctgatggacggcatgaac
gtcgtcggcgacctgttcggctcgggcaagatgttcctgccccaggtcgtgaagtcggcc
cgggtgatgaagaaggccgtcgcctacctgctgccctacatcgaggcggagaaggccgag
aacgggacgagtgcggccaaggacaccaacggcacgatcatcatggcgaccgtcaagggc
gacgtgcacgacatcggcaagaacatcgtcggagtcgtgttgcagtgcaacaacttcgag
gtcatcgacctcggggtgatggtgcccgcccagaagatcctggacgcggccaaggagcac
gacgccgacatcatcgggttgtccggactgatcacgccgtcgctggacgagatggtcaac
ttcgccgtagagatggagcgccagggcctcgagatccccctgctgatcggtggcgcgacg
acgtcacgcgcacacacggccgtgaagatctcaccgcgccgcagcggtccggtggtgtgg
gtcaaggacgcgtcgcgttcggtcccggtggccgccgcactcctcgacgacaagcagcgg
ccggccctgctcgaggccaccgagaaggactacgcgtcgctgcgcgaacggcacgcgcag
aagaacgagcggccgatgctgacgctggagaaggcgcgcgcgaaccgcacgccgatcgtg
tgggacgactacacgccgccggtgcccgcgcaaggtcttggcgtgcgcgagttctccgac
tacgacctcgccgaactgcgcgagtacatcgactggcagccgttcttcaacgcctgggag
ctcaagggccggttccccgacatcctgaacaacccggcgtcgggggagaccgcccgcaag
ctgtacgacgacgcgcaggaaatgctcgacaccctgatcaaggagaagtggctcaccgcc
aacggggtgatcggcttcttcccggcgaacgcggtcggcgacgacatcgaggtctacacc
gacgagagccgcaccgaggtgctcacgacgctgcgcaacctgcgccagcagggcgagcac
cgcgagggcatcccgaaccgcagcctgggcgacttcgtcgcccccaaggacacgggtctg
gccgactacgtcggcgcgttcgccgtcaccgcgggactgggcagcgcggagaagatcatc
gagttcaaggcggcccacgacgactacaacgcgatcctgctggagtcactggccgaccgg
ctggccgaggcgttcgccgaacgcatgcatcagcgggtccgcacggagttctggggctac
cagcccgaggagcatctcgacaacgacgcgctgatcggcgagaagtacgtcggcatccgt
ccggcgcccggctacccggcctgccccgagcacaccgagaagtcgacgctgtgggagctg
atggacgtcacgacacgcaccggcatcgagctcaccgagtcgatggcgatgtggcccggg
gccgccgtgagcgggtggtacttctcgcatccgcagtcgcagtacttcgtcgtcggccgg
ctggcccaggaccaggtcgccgactacgccaagcgcaagggctggacgctggccgaggcg
gagcgctggctcgccccgaacctgggctacaacccggaggactga
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