KEGG   MODULE: mrh_M00978
Entry
mrh_M00978        Pathway   Module                                 
Name
Ornithine-ammonia cycle
Definition
K01915 K01955+K01956 K00611 K01940 K01755 (K27542,K27545)
Diagram
mrh_M00978  Ornithine-ammonia cycle
mrh_M00978

Class
Pathway modules; Amino acid metabolism; Arginine and proline metabolism
Pathway
mrh00220  Arginine biosynthesis
mrh01100  Metabolic pathways
mrh01110  Biosynthesis of secondary metabolites
Organism
Mycolicibacterium rhodesiae [GN:mrh]
Gene
MycrhN_0716  N-dimethylarginine dimethylaminohydrolase [KO:K27545]
MycrhN_2083  glutamine synthetase, type III [KO:K01915]
MycrhN_2907  argininosuccinate lyase [KO:K01755]
MycrhN_2930  argininosuccinate lyase [KO:K01755]
MycrhN_4144  glutamine synthetase [KO:K01915]
MycrhN_4300  glutamine synthetase [KO:K01915]
MycrhN_4480  glutamine synthetase, type I [KO:K01915]
MycrhN_4485  glutamine synthetase, type I [KO:K01915]
MycrhN_4664  ornithine carbamoyltransferase [KO:K00611]
MycrhN_4666  argininosuccinate synthase [KO:K01940]
MycrhN_4667  argininosuccinate lyase [KO:K01755]
MycrhN_4889  glutamine synthetase [KO:K01915]
MycrhN_5375  carbamoyl-phosphate synthase, large subunit [KO:K01955]
MycrhN_5376  carbamoyl-phosphate synthase, small subunit [KO:K01956]
MycrhN_5700  glutamine synthetase [KO:K01915]
Reaction
R00253  
R00575  
R01398  
R01954  
R01086  
R13308  
Compound
C00014  Ammonia
C00064  L-Glutamine
C00169  Carbamoyl phosphate
C00327  L-Citrulline
C03406  N-(L-Arginino)succinate
C00062  L-Arginine
C00011  CO2
Reference
PMID:29632414
  Authors
Zhang H, Liu Y, Nie X, Liu L, Hua Q, Zhao GP, Yang C.
  Title
The cyanobacterial ornithine-ammonia cycle involves an arginine dihydrolase.
  Journal
Nat Chem Biol 14:575-581 (2018)
DOI:10.1038/s41589-018-0038-z
KO module
M00978
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