KEGG   Mycobacterium sp. JS623: Mycsm_03790
Entry
Mycsm_03790       CDS       T02423                                 
Name
(GenBank) methionine synthase (B12-dependent)
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
msa  Mycobacterium sp. JS623
Pathway
msa00270  Cysteine and methionine metabolism
msa00450  Selenocompound metabolism
msa00670  One carbon pool by folate
msa01100  Metabolic pathways
msa01110  Biosynthesis of secondary metabolites
msa01230  Biosynthesis of amino acids
msa04980  Cobalamin transport and metabolism
msa04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:msa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Mycsm_03790
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Mycsm_03790
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Mycsm_03790
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Mycsm_03790
   04980 Cobalamin transport and metabolism
    Mycsm_03790
Enzymes [BR:msa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Mycsm_03790
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding CdhD
Other DBs
NCBI-ProteinID: AGB24062
UniProt: L0J0C8
LinkDB
Position
complement(3703863..3707609)
AA seq 1248 aa
MSSESNNFVPNIRPDCTGELTAALRQRIMVIDGAMGTAIQRDRPDEAGYRGERFKDWPSD
LVGNNDLLTLTQPHIIEGIHREYLEAGADILETNTFNANAVSLSDYGMAELGYELNYAGA
VLARKACDEFSTPSKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLVSAYLDAARGL
VDGGADLLIVETIFDTLNAKAAVFAIETLFEDRGRRWPVIISGTITDASGRTLSGQVTEA
FWNSIRHAKPLAVGLNCALGAPEMRPYLAEMSRIADTFVSCYPNAGLPNAFGEYDESPKR
QAGYVADFAEAALVNLVGGCCGTTPAHIAEIAKVVDGKPPREVPKIEVATRLAGLEPLNI
TDDSLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMDEGMIDGV
AAMDRFTKLIASEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIVNSISMKEGEEKFIREA
RLCRKYGAAVVVMAFDEQGQADNLERRIQICGRAYRILTEEVGFPPEDIIFDPNCFALAT
GIEEHATYGIDFIEACSWIKENLPGVHISGGISNVSFSFRGNNPVREAIHSVFLFHAIKA
GLDMGIVNAGALVPYDSIDPELRDRIEDVVLNRREDAAERLLEIAERFNSSEKGEDPAAA
EWRGLPVRERITHALVKGIDAHVDADTEELRAEIAAAGGRPIEVIEGPLMDGMNVVGDLF
GSGKMFLPQVVKSARVMKKAVAYLLPFIEAEKVESGAAAGKDTNGTIIMATVKGDVHDIG
KNIVGVVLQCNNFEVIDLGVMVPAQKILDAAAEHGADIIGLSGLITPSLDEMVNFAAEME
RQGLEIPLLIGGATTSRAHTAVKVAPRRSGPVVWVKDASRSVPVAAALLDDKQRPALLEA
TEKDYASLRERHAHKNERPMLTLQMARANRTPIEWDGYQPPAPAQGLGVRDFHDYDLSEL
REYIDWQPFFNAWEMKGRFPDILNNPASGEAARKLYDDAQEMLDTLIKEKWLTANGVIGF
FPANAVGDDIEVYTDESRTEVLTTLHNLRQQGEHREGIPNRSLGDFVAPKDTGLADYVGA
FAVTSGLGSREKIAEFKAALDDYSAILLESIADRLAEAFAERMHERVRKEFWGYQPDEQL
DNEALIGEKYVGIRPAPGYPACPEHTEKVTLWKLMDVRERTGIELTESMAMWPGAAVSGW
YFSHPQSQYFVVGRLAQDQVADYARRKGWTLVEAERWLAPNLGYNPED
NT seq 3747 nt   +upstreamnt  +downstreamnt
gtgagctctgagtcgaacaacttcgtgccgaacatccgtcccgactgcaccggcgaactg
acggctgctttgcgccagcggatcatggtgatcgacggtgccatgggcacggcaatccag
cgggaccggccggacgaggccggttatcgcggcgagcggttcaaggactggccgagcgat
cttgtgggcaacaacgacctgctcaccctgacgcagccccacatcatcgagggcatccac
cgcgagtacctcgaggccggcgccgacatcctggagaccaacacgttcaacgcgaacgcg
gtctcgctgtccgactacggcatggccgagctgggctatgagctgaactacgccggcgcg
gtccttgcccgcaaggcctgcgacgagttcagcaccccgtccaagccgcgctacgtcgcc
ggcgccctcgggccgacgacgcggaccgcgtcgatctcgccggacgtcaacgatcccggc
gcccgcaacgtctcctacgaccagctcgtctccgcgtacctcgacgccgccagaggcctg
gtcgacggtggcgccgacctcctgatcgtcgagaccatcttcgacacactgaacgccaaa
gccgcggtgttcgccatcgagacgctgttcgaggaccgcggacgccgctggccggtgatc
atctcgggcaccatcaccgatgcgtccgggcggaccctatccggtcaggtgaccgaagcg
ttctggaattcgatcaggcatgccaagccgctcgcggtgggtctcaactgtgcgcttggc
gcgccggagatgagaccctacctcgccgagatgtcgcggatcgcagacactttcgtgtcc
tgctacccgaacgccggcctgcccaacgccttcggcgaatacgacgagtccccgaagcgt
caggccggctacgtcgccgattttgccgaggccgccctggtcaacctggtcggtggttgc
tgcggaacgacaccggcgcacatcgccgagatcgccaaggtcgtcgacggcaagccgcca
cgtgaggtgccgaagatcgaggtggccacccggctcgcgggcctggagccgctcaacatc
accgacgactccctgttcgtgaacatcggtgagcgcaccaacatcaccggctccgcccgg
ttccgcaacctgatcaaagccgaggactacgacaccgcgctgtcggtggccctgcagcag
gtcgaggtcggtgcacaggtcatcgacatcaacatggacgagggcatgatcgacggcgtc
gccgcgatggaccgcttcaccaagctgatcgcatccgagccggacatcagccgcgtcccg
gtgatgatcgactcctccaagtgggaggtcatcgaagcgggcctgaagaacgtgcagggc
aagccgatcgtcaactcgatctccatgaaggagggcgaggagaagttcatccgtgaggca
cggctgtgccgcaagtacggcgccgccgttgtcgtgatggccttcgacgaacagggtcag
gccgacaatctggagcgccgcatccagatctgtggacgcgcctaccggatcctgaccgaa
gaggtcggctttccgcccgaggacatcatcttcgacccgaactgctttgcgctcgcgacg
ggtatcgaggagcacgcgacgtacgggatcgacttcatcgaggcctgctcctggatcaag
gagaacctaccgggggtgcacatctccggcggtatctcgaacgtgtcgttctcgttccgc
ggcaacaaccccgtccgcgaggcgatccattcggtgttcctgttccacgccatcaaggcc
ggcctggacatgggcattgtcaacgcgggtgccctggtgccctacgactcgatcgacccc
gagctgcgggaccgcatcgaggacgtcgttctgaatcgtcgcgaggatgcggccgaaagg
ctcctggagatcgccgaacggttcaacagctcggagaagggcgaggacccggccgcagcc
gagtggcgcggtctgccggtccgcgagcggatcacgcacgccctggtcaagggcatcgac
gcccacgtcgacgccgacactgaggaattgcgggccgagatcgcggctgcgggtggtcgg
ccgatcgaggtgatcgagggcccgctgatggacggcatgaatgtcgtcggcgaccttttc
ggctcgggcaagatgttcctgccccaggtcgtgaagtcggccagggtgatgaagaaggcc
gtggcgtatctgctgccgttcatcgaggcggagaaagtggagtcgggcgctgctgcgggt
aaagacaccaacggcacgatcatcatggcgacggtgaagggcgacgtccatgacattggc
aaaaacatcgtcggggttgtcttgcagtgcaacaacttcgaagtgatcgacctcggtgtg
atggtgcccgcccagaagatcctggacgcggccgcggagcacggcgccgacatcatcggg
ctgtccgggctgatcaccccgtccctggacgagatggtcaacttcgccgccgagatggaa
cgccagggcctggagatcccgctgctgatcggcggcgcaaccacctcgcgcgctcacacg
gccgtgaaagtggcgccgcgtcgtagcggtccggtggtctgggtcaaggacgcttcccgc
tcggtcccggtcgctgcagcgctgctcgacgacaagcagcggcctgccctgctggaggcg
accgagaaggactacgcgtcgcttcgcgaacggcacgcccataagaacgagcggccgatg
ctgacgctccagatggcccgcgccaaccggacgccgatcgagtgggacggctaccagccg
ccggcgcctgcccagggcctcggcgtgcgggattttcatgactatgacctatcggagctg
cgcgagtacatcgactggcagccgttcttcaacgcctgggagatgaagggcagattcccg
gacatcctgaacaacccggcctcgggcgaggctgctcgcaagctgtatgacgacgcgcag
gagatgctcgacaccctgatcaaggagaagtggctgaccgccaacggggtcatcgggttc
ttcccggccaacgcggtcggcgacgacatcgaggtgtacaccgacgagagccgtaccgag
gtgttgaccacgttgcacaatctgcgccagcagggcgagcaccgcgagggcatcccgaac
cggtcgctgggcgacttcgtcgcgcccaaggacaccggtctggcggactacgtcggcgcc
ttcgcggtcacctccgggctcggcagccgggagaagatcgcggagttcaaggcggccctc
gacgactacagcgcgatcctgctggaatcgatcgccgaccggctggcggaggcgttcgcc
gaacggatgcacgaacgcgtccgcaaggagttctggggataccagcctgacgagcagctg
gacaacgaggcgctcatcggtgagaagtacgtgggaatccgcccggcccccggctacccc
gcctgcccggagcacaccgagaaggtgacgctctggaagctgatggacgtccgcgagcgc
acgggcatcgagctgaccgagtcgatggcgatgtggcccggtgctgccgtcagcggctgg
tacttctcgcacccgcagtcgcagtacttcgtggtcggccggttggcccaggatcaggtc
gccgactacgcgaggcgcaagggctggaccctggtcgaagcggaacgctggctcgccccc
aacctcggctacaacccggaggactga

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