Mycobacterium sp. JS623: Mycsm_04837
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Entry
Mycsm_04837 CDS
T02423
Name
(GenBank) 2-oxoglutarate dehydrogenase E1 component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
msa
Mycobacterium sp. JS623
Pathway
msa00020
Citrate cycle (TCA cycle)
msa00630
Glyoxylate and dicarboxylate metabolism
msa00785
Lipoic acid metabolism
msa01100
Metabolic pathways
msa01110
Biosynthesis of secondary metabolites
msa01120
Microbial metabolism in diverse environments
msa01200
Carbon metabolism
msa01210
2-Oxocarboxylic acid metabolism
Module
msa_M00009
Citrate cycle (TCA cycle, Krebs cycle)
msa_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
msa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
Mycsm_04837
00630 Glyoxylate and dicarboxylate metabolism
Mycsm_04837
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Mycsm_04837
Enzymes [BR:
msa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
Mycsm_04837
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
Mycsm_04837
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
Mycsm_04837
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
Mycsm_04837
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AGB25056
UniProt:
L0J465
LinkDB
All DBs
Position
4786544..4790284
Genome browser
AA seq
1246 aa
AA seq
DB search
MNSPSPFGQNEWLVEEMYRKFREDPSSVDPSWHEFLVDYSPEPTTETHPTIGNGQPAQAP
VAPPEPAPAPAPKTETSNGAAAAPAKVPEAAKAPEPAKAAEPAKAAARPAAPALTPAEGD
ETQVLRGAAAAVVKNMSASLEVPTATSVRAIPAKLMIDNRIVINNHLKRTRGGKISFTHL
IGYALVQAVKKFPNMNRHFAEVDGKPNAVTPEHVNLGLAIDLQGKDGNRQLVVAAIKGCE
TMQFGQFIAGYEDIVRRARDGKLTAEDFSGVTISLTNPGTIGTVHSVPRLMRGQGAILGV
GAMEYPAEFQGASEERISELGVGKLVTFTSTYDHRIIQGAESGDFLRTIHELLLSDDFFD
EIFRELGIPYEPVRWRTDNPDPIVDKNARVIELIAAYRNRGHLMADIDPLRLDKTRFRSH
PDLDVQNHGLTLWDLDREFKVDGFAGKEYKKLRDVLGLLRDAYCRHVGVEYTHILEPEQQ
KWLQERIEVKHDKPTVAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAETVIPMMDA
AIDQAAEHALDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKYHL
GATGNYIQMFGDNDIQVSLVANPSHLEAVDPVLEGLVRAKQDLLDKGDAPDGFSVVPMML
HGDAAFAGQGVVAETLNLALLRGYRTGGTIHIIVNNQIGFTTSPNDSRSSEYCTDVAKMI
GAPIFHVNGDDPEACVWVARLAMDFRQQFKKDVVIDMLCYRRRGHNEGDDPSMTQPYMYD
VIDTKRGSRKTYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRDLEKHPIAPSASVE
SDQMVPAGMTTAVDKSLLARIGDAHLAFPDDFNVHPRVMPVLEKRREMAYEGKVDWAFAE
LLALGTFLAEGKTIRLSGQDTRRGTFTQRHSVIIDRKTGREFTPLQLLTTNTDGTPTGGK
FMVYDSALSEFAAVGFEYGYSVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQL
SDVVLLLPHGHEGQGPDHTSARIERFLLLWAEGSMTIAMPSTPANYFHLLRRHGLDGIHR
PLIVATPKSMLRNKAAVSDLKDFTEGKFRSVIEEPTYDEGIGDRNKVKRMLLTSGKIYYE
LVARKNKDNREDVAIVRIEQLAPLPRRRLSETLDRYPNIEQYFWVQEEPANQGAWPTFGL
TLPEVCSDRLSGIKRISRRAMSAPSSGSSKVHAVEQQEIIDEAFAE
NT seq
3741 nt
NT seq
+upstream
nt +downstream
nt
gtgaactcaccatcaccattcggacagaacgagtggttggtcgaggagatgtatcgcaaa
tttcgcgaggatccctcgtcggtagacccgagttggcatgaattcttagtcgactactcc
cccgagccaactaccgaaacgcatcccaccatcggcaatgggcagccggcgcaggctccg
gtcgcgccgccggagccagcgcccgcacctgcgcccaagaccgagacaagcaacggcgcc
gccgctgcgcccgccaaggtgccggaagcggcgaaggcgccggaacccgcgaaggctgcg
gaaccggcgaaagctgcggccaggccggctgcccccgcattgaccccggccgaaggcgat
gagacgcaggtgctgcgcggtgccgccgcggcggtcgtgaagaacatgtcggcatccctt
gaggtgccgaccgcgaccagcgtgcgggccatccctgccaagctgatgatcgacaaccga
atcgtcatcaacaaccacctcaagcgcacccgcggcggcaagatctccttcacgcacctg
atcgggtacgcgttggtgcaggccgtcaagaagttcccgaacatgaaccgccacttcgcc
gaggtggacggcaagccgaatgcggtgacgcccgaacacgtcaacctcggtctcgcgatc
gacctgcagggcaaggacggcaaccggcaactagtcgttgcagccataaagggctgcgag
acaatgcaattcggtcagttcatcgccgggtacgaggacatcgtccggcgtgcccgcgac
ggcaagctgaccgccgaggacttctccggcgtgacgatctcgctgaccaacccgggcacc
atcggcaccgtgcactcggtgccgcggctgatgcgcggccagggcgcgatcctcggcgtc
ggcgcgatggagtatcccgcggagttccagggcgccagcgaggaacgcatctccgaactc
ggcgttggcaagctggtcacgttcacgtcgacctacgaccaccgcatcatccagggcgcc
gagtcgggcgacttcctgcgcacgatccacgaattgctgctgtccgacgactttttcgac
gaaatcttccgcgaactcggtatcccgtacgagccggtccggtggcgcaccgacaacccg
gacccgatcgtcgacaagaacgcccgcgtcatcgagctgatcgccgcctaccgcaaccgc
ggccacctgatggccgacatcgacccgctgcggctggacaagacccggttccgcagccac
cccgatctcgacgtgcagaaccacggcctgacgctgtgggatctggaccgcgagttcaag
gtcgacggcttcgcgggcaaggagtacaagaagctgcgcgacgtgctcggtctgctgcgc
gacgcgtactgccgccacgtcggtgtcgagtacacccacatcctcgagcccgagcagcag
aagtggctgcaggagcgcatcgaggtcaagcacgacaagccgaccgtcgcgcagcagaag
tacatcctctcgaagctgaatgccgccgaggcgttcgagacgttcctgcagaccaaatat
gtagggcagaaacgattctcgctcgagggcgccgagactgtcatcccgatgatggatgct
gccatcgatcaggccgccgagcatgcgctcgacgaggtcgtgatcggcatgccgcaccgc
ggcaggctcaacgtgctggccaacatcgtcggcaagccgtattcgcagatcttcagcgag
ttcgagggcaacctgaacccgtcgcaagcgcacggctccggtgacgtgaagtaccacctg
ggcgctaccggcaactacattcagatgttcggcgacaacgacattcaggtatcgctggtc
gccaacccgtcgcacctggaggccgtcgacccggttctcgagggtctggtccgcgcgaaa
caggacctgctcgacaagggggacgcgcccgacggcttctccgtcgtgccgatgatgctg
cacggcgatgccgcgttcgcgggccagggcgtggtggccgaaacgctgaacctggcgctg
ctgcgcggctaccgcaccggcgggaccatccacatcatcgtcaacaaccagatcggcttc
accacatcgccgaacgactcgcggtcctcggagtactgcaccgacgtcgcgaaaatgatt
ggcgcgccgatcttccacgtcaacggcgacgatcccgaggcgtgtgtctgggtggcgcgg
ctggccatggacttccgccagcagttcaagaaggacgtcgtcatcgacatgttgtgctac
cggcgccgcgggcacaacgagggcgatgacccgtcgatgacgcagccgtacatgtacgac
gtcatcgacaccaagcgcggctcccgcaagacctacaccgaggcactgatcggccgcggc
gacatctcgatgaaagaggccgaagacgcgctgcgcgactaccagggccagctggagcgg
gtgttcaacgaggtgcgcgacctcgagaagcatccgatcgccccgagcgcctcggtggag
tccgaccagatggtgcccgccgggatgaccaccgcggtggacaagtcgctgctggcccgc
atcggtgacgcgcatctggcgtttcccgacgatttcaacgtgcacccgcgtgtgatgccc
gtgctcgagaagcgcagggagatggcgtacgagggcaaggtcgactgggcgttcgcggag
ctacttgcgctcggcacgttcctggccgagggcaagacgattcggctgtccgggcaggac
acccgccgcggcacgttcacgcaacggcactcggtgatcatcgaccgcaagacgggtcgg
gagttcacaccgctgcagttgctgaccacgaacaccgacggcacgcccaccggcggcaag
ttcatggtgtacgactcggcgctgtcagagttcgccgccgtgggcttcgagtacggctac
tccgtcggcaatcccgacgcacttgtgttgtgggaggcgcagttcggcgacttcgtcaac
ggcgcgcagtcgatcatcgacgaattcatcagctccggcgaggccaagtggggccagctg
tccgacgtggtgctgctgctgcctcacggccacgagggccagggcccagaccacacgtcg
gcgcgcatcgagcggttcctgctgctgtgggctgagggctcgatgacgatcgcgatgccg
tcgacaccggcgaactacttccacctgctgcgccgccacggtctggacggcattcaccgg
ccgctgatcgtggcgacgccaaagtccatgctgcgcaacaaggctgcggtcagcgacctc
aaagacttcaccgagggcaagttccggtcagtcatcgaggaacccacctacgacgagggc
atcggcgaccgcaacaaggtcaagcggatgctgcttactagcggcaagatctactacgag
ctggtcgcgcggaagaacaaggacaaccgcgaggacgtcgcgatcgtccgcatcgagcag
ctcgctccattgcctcggcgacgcctgtccgagacgctggaccgttatccgaacatcgag
cagtacttctgggtgcaggaggagccggcgaaccagggcgcgtggccgacgttcgggctc
acgctgcccgaggtgtgctcggatcggctctccggcatcaaacggatttcgcgacgcgcg
atgtctgcgccatcgtcgggctcgtcgaaggtgcacgccgtcgagcagcaggagatcatc
gacgaggctttcgcggagtaa
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integrated database retrieval system
