Mycolicibacterium smegmatis MC2 155: LJ00_24970
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Entry
LJ00_24970 CDS
T03433
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
msb
Mycolicibacterium smegmatis MC2 155
Pathway
msb00020
Citrate cycle (TCA cycle)
msb00630
Glyoxylate and dicarboxylate metabolism
msb00785
Lipoic acid metabolism
msb01100
Metabolic pathways
msb01110
Biosynthesis of secondary metabolites
msb01120
Microbial metabolism in diverse environments
msb01200
Carbon metabolism
msb01210
2-Oxocarboxylic acid metabolism
Module
msb_M00009
Citrate cycle (TCA cycle, Krebs cycle)
msb_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
msb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
LJ00_24970 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
LJ00_24970 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LJ00_24970 (kgd)
Enzymes [BR:
msb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
LJ00_24970 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
LJ00_24970 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
LJ00_24970 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
LJ00_24970 (kgd)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AIU10087
UniProt:
A0R2B1
Structure
PDB
PDBj
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All DBs
Position
5148026..5151709
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AA seq
1227 aa
AA seq
DB search
MSSSPSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYSPEPTTDSASNGRTTTAAPV
TPPTPAPAPAPEPKAAPKPAAKTEAKPAKPAKSATPAKGDESQILRGAAAAVVKNMNASL
EVPTATSVRAIPAKLMIDNRVVINNHLKRTRGGKISFTHLLGYAIVQAVKKFPNMNRHFA
VVDGKPTAITPAHTNLGLAIDLQGKDGNRSLVVAAIKRCETMRFGQFIAAYEDIVRRARD
GKLTAEDFSGVTISLTNPGTLGTVHSVPRLMQGQGAIIGAGAMEYPAEFQGASEERIADL
GIGKLITLTSTYDHRIIQGAESGDFLRTIHQLLLDDDFFDEIFRELGIPYEPVRWRTDNP
DSIEDKNARVIELIAAYRNRGHLMADIDPLRLDNTRFRSHPDLDVNSHGLTLWDLDREFK
VDGFAGVQRKKLRDILSVLRDAYCRHVGVEYTHILEPEQQRWIQERVETKHDKPTVAEQK
YILSKLNAAEAFETFLQTKYVGQKRFSLEGAETVIPMMDAVIDQCAEHGLDEVVIAMPHR
GRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKYHLGATGTYIQMFGDNDIEVSLT
ANPSHLEAVDPVLEGLVRAKQDLLDTGEEGSDNRFSVVPLMLHGDAAFAGQGVVAETLNL
ALLRGYRTGGTIHIVVNNQIGFTTAPTDSRSSEYCTDVAKMIGAPIFHVNGDDPEACAWV
ARLAVDFRQAFKKDVVIDMLCYRRRGHNEGDDPSMTQPYMYDVIDTKRGSRKAYTEALIG
RGDISMKEAEDALRDYQGQLERVFNEVRELEKHEIEPSESVEADQQIPSKLATAVDKAML
QRIGDAHLALPEGFTVHPRVRPVLEKRREMAYEGRIDWAFAELLALGSLIAEGKLVRLSG
QDTQRGTFTQRHAVIVDRKTGEEFTPLQLLATNPDGTPTGGKFLVYNSALSEFAAVGFEY
GYSVGNPDAMVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDH
TSGRIERFLQLWAEGSMTIAMPSTPANYFHLLRRHGKDGIQRPLIVFTPKSMLRNKAAVS
DIRDFTESKFRSVLEEPMYTDGEGDRNKVTRLLLTSGKIYYELAARKAKENREDVAIVRI
EQLAPLPRRRLAETLDRYPNVKEKFWVQEEPANQGAWPSFGLTLPEILPDHFTGLKRISR
RAMSAPSSGSSKVHAVEQQEILDTAFG
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagttcaccttcaccattcggacagaacgagtggctggtcgaggagatgtatcgc
aaattccgcgatgacccctcctcggtggatcccagttggcatgaatttctggtcgattac
tcccccgagcccaccaccgacagtgcctccaacgggcgcaccaccaccgcggctcccgtg
acgccgccgactccggcgcctgcgcccgcgcccgagcccaaggccgcgcccaagcccgcc
gcgaagaccgaggccaagcccgccaagccggcgaagtcggccaccccggccaagggcgac
gaatcgcagatcctgcgcggcgccgcggcagcggtggtcaagaacatgaacgcctcgctg
gaggtgccgaccgcgacgagcgtgcgcgccatcccggcgaagctgatgatcgacaaccgc
gtcgtcatcaacaaccacctcaagcgcacgcgcggcggcaagatcagcttcacccacctg
ctgggctacgcgatcgtgcaggcggtcaagaagttcccgaacatgaaccgccacttcgcg
gtcgtcgacggcaagcccaccgcgatcacgcccgcccacaccaacctgggcctcgcgatc
gacctgcagggcaaggacggcaaccgctcgctcgttgtcgcggcgatcaagcgttgcgag
acaatgcgattcggccagttcatcgccgcatacgaggacatcgtacgtcgcgcgcgtgac
ggcaagctcaccgccgaggacttctcgggcgtcaccatctctctcaccaatcccggcact
ctgggcaccgtccactcggtgcccagactcatgcagggacagggtgcgatcatcggcgcg
ggcgccatggagtaccccgccgagttccagggcgccagcgaggagcgcatcgccgacctg
ggcatcggcaagctgatcacactgacgtcgacctacgaccaccgcatcatccagggtgcg
gagtccggcgacttcctgcgcaccatccaccagctgctgctcgacgacgacttcttcgac
gagatcttccgcgagctgggcatcccgtacgagcccgtgcgctggcgcaccgacaacccc
gactcgatcgaggacaagaacgcgcgcgtcatcgagctcatcgcggcgtaccgcaaccgc
ggtcacctgatggccgacatcgatccgctgcgcctggacaacacccggttccgcagccac
ccggacctcgacgtcaacagccacggcctgaccctgtgggacctcgaccgcgagttcaag
gtcgacgggttcgccggtgtgcagcgcaagaagctgcgcgacatcctctcggtgctgcgc
gacgcgtactgccgccacgtcggtgtcgagtacacccacatcctcgagcccgagcagcag
cgctggatccaggaacgcgtcgagaccaagcacgacaagccgacggtcgccgagcagaag
tacatcctgtccaagctcaacgccgccgaggccttcgagaccttcctgcagaccaaatac
gttgggcagaagcgcttctcgctcgaaggcgccgagaccgtcatcccgatgatggacgcc
gtgatcgaccagtgcgccgagcacggtctcgacgaggtggtcatcgcgatgccgcaccgc
ggccgcctcaacgtgctcgccaacatcgtcggcaagccctacagccagatcttcagcgag
ttcgagggcaacctcaacccgtcacaggcgcacggctccggcgacgtgaagtaccacctg
ggcgccaccggcacctacatccagatgttcggcgacaacgacatcgaggtgtcgctgacc
gccaaccccagccacctcgaagccgtcgacccggtgctcgaaggtctggtgcgcgccaag
caggacctgctcgacacgggcgaggagggctccgacaaccgcttctccgtcgtgccgttg
atgctgcacggcgacgcggccttcgcgggccagggcgtggtggccgagacgctcaacctc
gcgctgctgcgcggctaccgcacgggcggcacgatccacatcgtcgtcaacaaccagatc
gggttcaccacggcgcccacggattcgcgctccagcgagtactgcaccgacgtggccaag
atgatcggcgcgccgatcttccacgtcaacggcgacgatcccgaggcgtgcgcctgggtg
gcgcgcctggccgtcgacttccggcaggcgttcaagaaggacgtcgtcatcgacatgctg
tgctaccgccgccgcggccacaacgagggcgacgacccgtcgatgacgcagccctacatg
tacgacgtcatcgacaccaagcgcggctcccgcaaggcctacaccgaggccctgatcggc
cgcggtgacatctcgatgaaagaggccgaggacgccctgcgcgactaccagggccagctc
gagcgggtgttcaacgaggtccgcgagctcgaaaaacacgagatcgagcccagtgagtcc
gtcgaggccgaccagcagatcccgagcaagctcgccacggccgtcgacaaggcgatgctg
cagcgcatcggcgatgcgcacctcgcgctgcccgagggcttcacggtgcacccgcgtgtg
cggccggtgctggagaagcgccgcgagatggcctacgagggccgcatcgactgggcgttc
gccgagctgctcgcgctcggctcgctcatcgccgagggcaagctcgtgcggctttcgggt
caggacacgcagcgcggcacgttcacacagcgccacgcggtgatcgtcgaccgcaagacc
ggcgaggagttcacgccgctgcagctgttggccaccaaccccgacggcacacccaccggc
ggcaagttcctggtgtacaactccgcgctgagcgagttcgccgcggtgggcttcgagtac
ggctactcggtgggcaaccccgacgccatggtgctgtgggaggcgcagttcggcgacttc
gtcaacggcgcgcagtcgatcatcgacgagttcatcagctcgggcgaggccaagtggggt
cagctgtccgatgtcgtgctgctgctgccgcacggccacgagggccagggccccgaccac
acctcgggacgcatcgagcgcttcctgcagctgtgggccgagggttcgatgaccattgcc
atgccgtcgacgccggcgaactacttccacctgctgcgcaggcacggcaaggacggcatc
cagcgtccgctgatcgtgttcacgcccaagtcgatgctgcgcaacaaggccgccgtcagc
gacatccgcgacttcaccgagagcaagttccgctcggtgctcgaggagccgatgtacacc
gacggtgaaggcgaccgcaacaaggtcacgcgcctgctgctgaccagcggcaagatctac
tacgagctcgccgcgcgcaaggccaaggagaaccgcgaggacgtcgcgatcgtgcgtatc
gagcagctcgcgccgctgccgcggcgcaggctcgccgagacgctcgaccggtacccgaac
gtcaaggagaagttctgggtgcaggaggagccggccaaccagggcgcatggccgtccttc
gggttgacgctccccgagatcctcccggaccacttcacgggcctcaagcgcatctcgcgg
cgcgccatgtcggcgccgtcgtcgggttcgtcgaaggtgcacgccgtcgagcagcaggag
atcctcgacacagcgttcggctga
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