Mycobacterium shigaense: MSG_03166
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Entry
MSG_03166 CDS
T05717
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mshg
Mycobacterium shigaense
Pathway
mshg00010
Glycolysis / Gluconeogenesis
mshg00020
Citrate cycle (TCA cycle)
mshg00620
Pyruvate metabolism
mshg00785
Lipoic acid metabolism
mshg01100
Metabolic pathways
mshg01110
Biosynthesis of secondary metabolites
mshg01120
Microbial metabolism in diverse environments
mshg01200
Carbon metabolism
mshg01210
2-Oxocarboxylic acid metabolism
Module
mshg_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mshg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MSG_03166 (aceE)
00020 Citrate cycle (TCA cycle)
MSG_03166 (aceE)
00620 Pyruvate metabolism
MSG_03166 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MSG_03166 (aceE)
Enzymes [BR:
mshg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MSG_03166 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
BAX93304
UniProt:
A0A1Z4EK22
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Position
3351332..3354121
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AA seq
929 aa
AA seq
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MTTEFARHDLAKTPSNGSEPDRVRVIREGVASYLPDIDPEETSEWLESFDELLERSGPSR
ARYLMLRLLERAGEQRIAIPALTSTDYVNTIPTELEPWFPGDEDVERRFRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGNSHPGGGDQVFIQGHASPGIYARAF
LEGRLTEDRMDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHY
LHDRGIKDTSDQHVWAFLGDGEMDEPESRGLIQVAANEGLDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVADMSDSEIWNLKRGGHDYRKVYAAYRAAVDHRGQPTVILAKT
IKGYSLGAHFQGRNATHQMKKLALQDLKDFRDAIRIPITDAQLEEDPYLPPYYHPGPDAP
EIRYMLDRRRTLGGFVPERRTKAKALKQPSRDIYAPLKKGSGHQEVATTMAIVRTFKEVL
RDKEIGPRIVPIIPDEARTFGMDSWFPSLKIYNRLGQLYTAVDADLMLAYKESEIGQILH
EGINEAGSTASFTAAGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAADQMARGFVLGA
TAGRTTLTGEGLQHADGHSLLLAATNPAVIAYDPAFAFEIAYIVESGLARMFGQDPENVY
FYITVYNEPYVQPPEPENFDPEGVLRGIYRYHAATEQRSNKAQLLASGVAMPSALKAAEL
LAAEWDVAADVWSVTSWGELNRDGVAVQREQLRHPDQPAGTPYVAKALSGVTGPVVAVSD
WMRAVPEQIRPWVPNTYVTLGTDGFGFSDTRPAARRFFNTDAESQVVAVLEALARDGEID
PSVPLAAARQYKIDDVLAAPKQTSDPGVA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
gtgacgaccgagttcgcacgccatgatctggcgaaaaccccaagcaacggaagcgaaccc
gaccgggttcgggtgattcgcgaaggtgtggcgtcatacctccccgacatcgaccccgaa
gagacctcggagtggttggagtccttcgacgagttgctcgagcgctcggggccgtcgcgg
gcccgatatctgatgctgcggttgctggaacgggccggcgagcagcgcatcgcgatcccg
gcgctgacgtccaccgactatgtgaacaccatcccgaccgagctcgagccgtggttcccc
ggcgacgaggatgtcgagcggcgcttccgcgcctggatccgatggaacgccgcgatcatg
gtgcatcgcgcccagcgcccgggagtcggcgtgggcggccacatttcgacgtatgcctcg
tcggcggcgctgtacgaggtcggcttcaatcacttcttccgcggcaattcgcatcccggc
ggcggcgaccaggtgttcatccagggccacgcctcccccggcatttacgcgcgcgccttc
ctggaaggccgcctgaccgaggaccggatggacggcttccgccaggagcacagccacccc
ggcggcggattgccgtcctatccgcacccccggctgatgcccgacttctgggagttcccc
acggtgtcgatggggctcggcccgatgaacgccatctatcaggcccgtttcaaccactac
ctgcacgaccgcggcatcaaggacacctccgatcagcacgtgtgggcgtttctcggcgac
ggcgagatggacgagccggaaagccgcggcctgatccaggtggccgccaacgaggggctg
gacaacctgaccttcgtcatcaactgcaacctgcagcgcctcgacggcccggtgcgcggc
aacggcaagatcatccaggagctggagtcgttcttccggggcgccggctggaacgtcatc
aaggtggtgtggggtcgcgagtgggacgcgctgctgcacgccgaccgcgacggtgcactg
gtcaacctgatgaacaccacgcccgacggcgactaccagacctacaaggccaacgacggc
gcgtacgtgcgcgaccacttcttcggccgcgacccgcggaccaaggcgctcgttgccgac
atgagcgattcggagatctggaacctcaagcgcggcgggcacgactaccgcaaggtgtac
gccgcgtaccgggccgcggtcgaccaccggggccagcccacggtgatcctggccaagacc
atcaaggggtactcgctgggcgcgcacttccagggacgcaacgccacgcaccagatgaaa
aagcttgcgctgcaagatctcaaggacttccgcgacgccatccggatcccgatcaccgac
gcccagctggaagaggacccctacctgccgccctactaccaccccggtcccgacgccccc
gagatccggtacatgctggaccgccgccgcacgctgggcggctttgtgcccgagcgccgg
accaaggccaaggccctcaagcagcccagccgcgacatctatgccccgctgaagaagggg
tcgggtcatcaggaggtcgccaccacgatggcgatcgtgcgcaccttcaaggaagtgttg
cgggacaaggagatcggcccacgcatcgtgccgatcattcccgacgaggcccgcaccttc
ggcatggactcctggttcccgtcgctgaagatctacaaccggctcggccagctgtacacc
gccgtggacgccgatttgatgttggcgtacaaggaaagtgagatcggccagatcctgcac
gagggcatcaacgaggccggttcgacggcgtcgttcaccgcggccggcacgtcatacgcc
acgcacaacgagccgatgatcccgatctacatcttctattcgatgttcgggttccagcgc
accggcgacggcttgtgggccgcggccgaccagatggcgcgcggcttcgtgctgggcgcc
acggcggggcgcaccaccctgaccggtgagggcctgcagcacgccgacgggcactcgctg
ctgctggccgccaccaatccggcggtaatcgcctacgatccggcgttcgccttcgagatc
gcctacatcgtcgagagcgggctagcccggatgttcgggcaggacccggagaacgtgtac
ttctacatcaccgtctacaacgagccctacgtgcagccgccggagccggagaacttcgat
cccgagggcgtgctgcgcggcatctatcgctaccacgcggccaccgagcagcgctccaac
aaggcccagctcctggcctccggggtggcgatgccctcggcactcaaagccgccgagctg
ctggccgccgagtgggacgtcgccgccgacgtgtggtcggtaaccagctggggcgagctg
aaccgcgacggcgtggccgtccagcgcgagcagctgcgccaccccgaccagcccgcgggc
actccctacgtggccaaggcgctgtccggggtcaccgggccggtcgtcgccgtctcggac
tggatgcgcgcggtacccgagcagatccggccgtgggttcccaacacctacgtgaccctg
ggcaccgacggcttcggcttctccgacacccgccccgccgcgcgccggttcttcaacacc
gacgccgagtcgcaggtggtggcggtgctcgaggcgctggcccgcgacggcgagatcgac
ccgtcggtcccgctggcggcggcccgccagtacaagatcgacgacgtgctggccgccccg
aagcagacctcggaccccggagtcgcgtga
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